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Photo of  Alex B. Lentsch, PHD

Alex B. Lentsch, PHD

Department Chair

Senior Associate Dean for Faculty Affairs & Development; Jacob G. Schmidlap Professor and Chairman, Department of Environmental and Public Health Sciences; Professor of Surgery

Environmental & Public Health Sciences | College of Medicine

Education/Credentials
  • Doctoral Degree: University of Louisville (Physiology and Biophysics)
  • Bachelor's Degree: Northern Kentucky University (Biological Sciences)
Contact Information
Research Interests

Inflammation, Liver Injury, Trauma, Military Medicine

Peer Reviewed Publications

Zingg, S Whitney; Schuster, Rebecca; Joseph, Bernadin; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2022. Storage with ethanol attenuates the red blood cell storage lesion. Surgery, 172 6, 1829-1836

Pulliam, Kasiemobi E; Joseph, Bernadin; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2021. Improving packed red blood cell storage with a high-viscosity buffered storage solution. Surgery, ,

Pulliam, Kasiemobi E; Joseph, Bernadin; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2021. Washing packed red blood cells decreases red blood cell storage lesion formation. Surgery, 169 3, 666-670

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2021. Expired But Not Yet Dead: Examining the Red Blood Cell Storage Lesion in Extended-Storage Whole Blood. Shock (Augusta, Ga.), 55 4, 526-535

Beckmann, Nadine; Sutton, Jeffrey M; Hoehn, Richard S; Jernigan, Peter L; Friend, Lou Ann; Johanningman, Taylor A; Schuster, Rebecca M; Lentsch, Alex B; Caldwell, Charles C; Pritts, Timothy A 2020. IFN? and TNF? mediate CCL22/MDC production in alveolar macrophages after hemorrhage and resuscitation. American journal of physiology. Lung cellular and molecular physiology, 318 5, L864-L872

Jung, Andrew D; Friend, Lou Ann; Stevens-Topie, Sabre; Schuster, Rebecca; Lentsch, Alex B; Gavitt, Brian; Caldwell, Charles C; Pritts, Timothy A 2020. Direct Peritoneal Resuscitation Improves Survival in a Murine Model of Combined Hemorrhage and Burn Injury. Military medicine, 185 9-10, e1528-e1535

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2020. Save it-don't waste it! Maximizing utilization of erythrocytes from previously stored whole blood. The journal of trauma and acute care surgery, 89 4, 665-672

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A 2017. Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion. Shock (Augusta, Ga.), 47 5, 632-637

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A 2017. Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation. Annals of surgery, 265 1, 218-226

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A 2016. Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation. Annals of surgery, ,

Nojima, Hiroyuki; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B 2016. Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. Journal of hepatology, 64 1, 60-8

Nojima, Hiroyuki; Konishi, Takanori; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B 2016. Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. PloS one, 11 8, e0161443

Jin, Shunying; Merchant, Michael L; Ritzenthaler, Jeffrey D; McLeish, Kenneth R; Lederer, Eleanor D; Torres-Gonzalez, Edilson; Fraig, Mostafa; Barati, Michelle T; Lentsch, Alex B; Roman, Jesse; Klein, Jon B; Rane, Madhavi J 2015. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. PloS one, 10 4, e0121637

Nojima, Hiroyuki; Freeman, Christopher M; Gulbins, Erich; Lentsch, Alex B 2015. Sphingolipids in liver injury, repair and regeneration. Biological chemistry, 396 6-7, 633-43

Wilson, Gregory C; Freeman, Christopher M; Kuethe, Joshua W; Quillin, Ralph C; Nojima, Hiroyuki; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B 2015. CXC chemokine receptor-4 signaling limits hepatocyte proliferation after hepatic ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 308 8, G702-9

Wilson, Gregory C; Kuboki, Satoshi; Freeman, Christopher M; Nojima, Hiroyuki; Schuster, Rebecca M; Edwards, Michael J; Lentsch, Alex B 2015. CXC chemokines function as a rheostat for hepatocyte proliferation and liver regeneration. PloS one, 10 3, e0120092

Chatterjee, Tapan K; Basford, Joshua E; Knoll, Ellen; Tong, Wilson S; Blanco, Victor; Blomkalns, Andra L; Rudich, Steven; Lentsch, Alex B; Hui, David Y; Weintraub, Neal L 2014. HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes, 63 1, 176-87

Freeman, Christopher M; Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Johnson, Bobby L; Sutton, Jeffrey M; Schuster, Rebecca M; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B 2014. Characterization of microparticles after hepatic ischemia-reperfusion injury. PloS one, 9 5, e97945

Pewzner-Jung, Yael; Tavakoli Tabazavareh, Shaghayegh; Grassmé, Heike; Becker, Katrin Anne; Japtok, Lukasz; Steinmann, Jörg; Joseph, Tammar; Lang, Stephan; Tuemmler, Burkhard; Schuchman, Edward H; Lentsch, Alex B; Kleuser, Burkhard; Edwards, Michael J; Futerman, Anthony H; Gulbins, Erich 2014. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. EMBO molecular medicine, 6 9, 1205-14

Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher H; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B 2014. Inhibition of Acidic Sphingomyelinase Reduces Established Hepatic Fibrosis in Mice. Hepatology research : the official journal of the Japan Society of Hepatology, ,

Richter, Jillian R; Sutton, Jeffrey M; Belizaire, Ritha M; Friend, Lou Ann; Schuster, Rebecca M; Johannigman, Taylor A; Miller, Steven G; Lentsch, Alex B; Pritts, Timothy A 2014. Macrophage-derived chemokine (CCL22) is a novel mediator of lung inflammation following hemorrhage and resuscitation. Shock (Augusta, Ga.), 42 6, 525-31

Stewart, Rachel K; Dangi, Anil; Huang, Chao; Murase, Noriko; Kimura, Shoko; Stolz, Donna B; Wilson, Gregory C; Lentsch, Alex B; Gandhi, Chandrashekhar R 2014. A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury. Journal of hepatology, 60 2, 298-305

Yang, Sung; Stepien, David; Hanseman, Dennis; Robinson, Bryce; Goodman, Michael D; Pritts, Timothy A; Caldwell, Charles C; Remick, Daniel G; Lentsch, Alex B 2014. Substance P mediates reduced pneumonia rates after traumatic brain injury. Critical care medicine, 42 9, 2092-100

Goodman, Michael D; Makley, Amy T; Campion, Eric M; Friend, Lou Ann W; Lentsch, Alex B; Pritts, Timothy A 2013. Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury. The Journal of surgical research, 184 2, 1053-8

Uriarte, Silvia M; Rane, Madhavi J; Merchant, Michael L; Jin, Shunying; Lentsch, Alex B; Ward, Richard A; McLeish, Kenneth R 2013. Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats. Shock (Augusta, Ga.), 39 3, 286-92

Van Sweringen, Heather L; Sakai, Nozomu; Quillin, Ralph C; Bailey, Jeff; Schuster, Rebecca; Blanchard, John; Goetzman, Holly; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B 2013. Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 57 1, 331-8

Yang, Sung H; Gangidine, Matt; Pritts, Timothy A; Goodman, Michael D; Lentsch, Alex B 2013. Interleukin 6 mediates neuroinflammation and motor coordination deficits after mild traumatic brain injury and brief hypoxia in mice. Shock (Augusta, Ga.), 40 6, 471-5

Yang, Sung H; Gustafson, Josh; Gangidine, Matt; Stepien, David; Schuster, Rebecca; Pritts, Timothy A; Goodman, Michael D; Remick, Daniel G; Lentsch, Alex B 2013. A murine model of mild traumatic brain injury exhibiting cognitive and motor deficits. The Journal of surgical research, 184 2, 981-8

Ziobro, Regan; Henry, Brian; Edwards, Michael J; Lentsch, Alex B; Gulbins, Erich 2013. Ceramide mediates lung fibrosis in cystic fibrosis. Biochemical and biophysical research communications, 434 4, 705-9

Belizaire, Ritha M; Makley, Amy T; Campion, Eric M; Sonnier, Dennis I; Goodman, Michael D; Dorlac, Warren C; Friend, Lou Ann; Lentsch, Alex B; Pritts, Timothy A 2012. Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage. The journal of trauma and acute care surgery, 73 2 Suppl 1, S128-33

Belizaire, Ritha M; Prakash, Priya S; Richter, Jillian R; Robinson, Bryce R; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B; Pritts, Timothy A 2012. Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation. Journal of the American College of Surgeons, 214 4, 648-55; discussion 6

Earnest, Ryan E; Sonnier, Dennis I; Makley, Amy T; Campion, Eric M; Wenke, Joseph C; Bailey, Stephanie R; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Supplemental oxygen attenuates the increase in wound bacterial growth during simulated aeromedical evacuation in goats. The journal of trauma and acute care surgery, 73 1, 80-6

Lentsch, Alex B 2012. Regulatory mechanisms of injury and repair after hepatic ischemia/reperfusion. Scientifica, 2012 , 513192

Makley, Amy T; Belizaire, Ritha; Campion, Eric M; Goodman, Michael D; Sonnier, Dennis I; Friend, Lou Ann; Schuster, Rebecca M; Bailey, Stephanie R; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Simulated aeromedical evacuation does not affect systemic inflammation or organ injury in a murine model of hemorrhagic shock. Military medicine, 177 8, 911-6

Makley, Amy T; Goodman, Michael D; Belizaire, Ritha M; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Damage control resuscitation decreases systemic inflammation after hemorrhage. The Journal of surgical research, 175 2, e75-82

Prakash, Priya S; Caldwell, Charles C; Lentsch, Alex B; Pritts, Timothy A; Robinson, Bryce R H 2012. Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response. The journal of trauma and acute care surgery, 73 2, 401-6; discussion 40

Sakai, Nozomu; Van Sweringen, Heather L; Belizaire, Ritha M; Quillin, Ralph Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells. Journal of gastroenterology and hepatology, 27 10, 1609-16

Sakai, Nozomu; Van Sweringen, Heather L; Quillin, R Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 56 4, 1468-78

Sakai, Nozomu; Van Sweringen, Heather L; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Receptor activator of nuclear factor-?B ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice. Hepatology (Baltimore, Md.), 55 3, 888-97

Sonnier, Dennis I; Bailey, Stephanie R; Schuster, Rebecca M; Gangidine, Matthew M; Lentsch, Alex B; Pritts, Timothy A 2012. Proinflammatory chemokines in the intestinal lumen contribute to intestinal dysfunction during endotoxemia. Shock (Augusta, Ga.), 37 1, 63-9

Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. American journal of physiology. Gastrointestinal and liver physiology, 303 5, G546-60

Clarke, Callisia; Kuboki, Satoshi; Sakai, Nozomu; Kasten, Kevin R; Tevar, Amit D; Schuster, Rebecca; Blanchard, John; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B 2011. CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury. Hepatology (Baltimore, Md.), 53 1, 261-71

Clarke, Callisia; Sakai, Nozomu; Tevar, Amit D; Schuster, Rebecca; Edwards, Michael J; Lentsch, Alex B 2011. STAT3 does not regulate acute liver injury after ischemia/reperfusion. The Journal of surgical research, 171 2, 814-8

Elson, Joshua K; Beebe-Dimmer, Jennifer L; Morgenstern, Hal; Chilkuri, Mahdavi; Blanchard, John; Lentsch, Alex B 2011. The Duffy Antigen/Receptor for Chemokines (DARC) and prostate-cancer risk among Jamaican men. Journal of immigrant and minority health / Center for Minority Public Health, 13 1, 36-41

Goodman, Michael D; Makley, Amy T; Huber, Nathan L; Clarke, Callisia N; Friend, Lou Ann W; Schuster, Rebecca M; Bailey, Stephanie R; Barnes, Stephen L; Dorlac, Warren C; Johannigman, Jay A; Lentsch, Alex B; Pritts, Timothy A 2011. Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury. The Journal of surgical research, 165 1, 30-7

Sakai, N; Kuboki, S; Van Sweringen, H L; Tevar, A D; Schuster, R; Blanchard, J; Edwards, M J; Lentsch, A B 2011. CXCR1 deficiency does not alter liver regeneration after partial hepatectomy in mice. Transplantation proceedings, 43 5, 1967-70

Sakai, Nozomu; Shin, Thomas; Schuster, Rebecca; Blanchard, John; Lentsch, Alex B; Johnson, William Thomas; Schuschke, Dale A 2011. Marginal copper deficiency increases liver neutrophil accumulation after ischemia/reperfusion in rats. Biological trace element research, 142 1, 47-54

Sonnier, Dennis I; Makley, Amy T; Friend, Lou Ann W; Bailey, Stephanie R; Lentsch, Alex B; Pritts, Timothy A 2011. Hemorrhagic shock induces a proinflammatory milieu in the gut lumen. The Journal of surgical research, 170 2, 272-9

Tevar, Amit D; Clarke, Callisia N; Schuster, Rebecca; Wang, Jiang; Edwards, Michael J; Lentsch, Alex B 2011. The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis. The Journal of surgical research, 169 1, e7-14

Thobe, M N; Gray, J K; Gurusamy, D; Paluch, A M; Wagh, P K; Pathrose, P; Lentsch, A B; Waltz, S E 2011. The Ron receptor promotes prostate tumor growth in the TRAMP mouse model. Oncogene, 30 50, 4990-8

Van Sweringen, Heather L; Sakai, Nozomu; Tevar, Amit D; Burns, Justin M; Edwards, Michael J; Lentsch, Alex B 2011. CXC chemokine signaling in the liver: impact on repair and regeneration. Hepatology (Baltimore, Md.), 54 4, 1445-53

Goodman, Michael D; Makley, Amy T; Lentsch, Alex B; Barnes, Stephen L; Dorlac, Gina R; Dorlac, Warren C; Johannigman, Jay A; Pritts, Timothy A 2010. Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly? The Journal of surgical research, 164 2, 286-93

Huber, Nathan L; Bailey, Stephanie R; Schuster, Rebecca M; Ogle, Cora K; Lentsch, Alex B; Pritts, Timothy A 2010. Remote thermal injury increases LPS-induced intestinal IL-6 production. The Journal of surgical research, 160 2, 190-5

Kasten, Kevin R; Goetzman, Holly S; Reid, Maria R; Rasper, Alison M; Adediran, Samuel G; Robinson, Chad T; Cave, Cindy M; Solomkin, Joseph S; Lentsch, Alex B; Johannigman, Jay A; Caldwell, Charles C 2010. Divergent adaptive and innate immunological responses are observed in humans following blunt trauma. BMC immunology, 11 , 4

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Deters, Joseph S; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2010. Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock. The Journal of trauma, 68 2, 305-11

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2010. Murine blood banking: characterization and comparisons to human blood. Shock (Augusta, Ga.), 34 1, 40-5

Sakai, Nozomu; Clarke, Callisia N; Schuster, Rebecca; Blanchard, John; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2010. Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes. World journal of gastroenterology : WJG, 16 30, 3816-26

Sonnier, Dennis I; Bailey, Stephanie R; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A 2010. TNF-? induces vectorial secretion of IL-8 in Caco-2 cells. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 14 10, 1592-9

Tevar, Amit D; Clarke, Calissia; Wang, Jiang; Rudich, Steven M; Woodle, E Steve; Lentsch, Alex B; Edwards, Michael L 2010. Clinical review of nonalcoholic steatohepatitis in liver surgery and transplantation. Journal of the American College of Surgeons, 210 4, 515-26

Clarke, Callisia N; Kuboki, Satoshi; Tevar, Amit; Lentsch, Alex B; Edwards, Michael 2009. CXC chemokines play a critical role in liver injury, recovery, and regeneration. American journal of surgery, 198 3, 415-9

Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B 2009. Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 2, G266-74

Flierl, Michael A; Rittirsch, Daniel; Nadeau, Brian A; Sarma, J Vidya; Day, Danielle E; Lentsch, Alex B; Huber-Lang, Markus S; Ward, Peter A 2009. Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. PloS one, 4 2, e4414

Golab, Fereshteh; Kadkhodaee, Mehri; Zahmatkesh, Maryam; Hedayati, Mehdi; Arab, Hossein; Schuster, Rebecca; Zahedi, Kamyar; Lentsch, Alex B; Soleimani, Manoocher 2009. Ischemic and non-ischemic acute kidney injury cause hepatic damage. Kidney international, 75 8, 783-92

Huber, Nadine; Sakai, Nozomu; Eismann, Thorsten; Shin, Thomas; Kuboki, Satoshi; Blanchard, John; Schuster, Rebecca; Edwards, Michael J; Wong, Hector R; Lentsch, Alex B 2009. Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion. Hepatology (Baltimore, Md.), 49 5, 1718-28

Kuboki, Satoshi; Sakai, Nozomu; Clarke, Callisia; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B 2009. The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury. Journal of hepatology, 51 2, 296-306

Kuboki, Satoshi; Sakai, Nozomu; Tschöp, Johannes; Edwards, Michael J; Lentsch, Alex B; Caldwell, Charles C 2009. Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury. American journal of physiology. Gastrointestinal and liver physiology, 296 5, G1054-9

Lewis, Jaime D; Pritts, Timothy A; Lentsch, Alex B; Edwards, Michael J 2009. The University of Cincinnati College of Medicine Department of Surgery. The American surgeon, 75 2, 113-9

Tschöp, Johannes; Kasten, Kevin R; Nogueiras, Ruben; Goetzman, Holly S; Cave, Cynthia M; England, Lisa G; Dattilo, Jonathan; Lentsch, Alex B; Tschöp, Matthias H; Caldwell, Charles C 2009. The cannabinoid receptor 2 is critical for the host response to sepsis. Journal of immunology (Baltimore, Md. : 1950), 183 1, 499-505

Zahedi, Kamyar; Lentsch, Alex B; Okaya, Tomohisa; Barone, Sharon; Sakai, Nozomu; Witte, David P; Arend, Lois J; Alhonen, Leena; Jell, Jason; Jänne, Juhani; Porter, Carl W; Soleimani, Manoocher 2009. Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 4, G899-909

Zingarelli, Basilia; Hake, Paul W; O'Connor, Michael; Burroughs, Timothy J; Wong, Hector R; Solomkin, Joseph S; Lentsch, Alex B 2009. Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Critical care medicine, 37 6, 1978-87

Caldwell, Charles C; Lentsch, Alex B 2008. Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion. Gastroenterology, 135 5, 1460-2

Galloway, Elizabeth; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Kuboki, Satoshi; Schuster, Rebecca; Blanchard, John; Wong, Hector R; Lentsch, Alex B 2008. Activation of hepatocytes by extracellular heat shock protein 72. American journal of physiology. Cell physiology, 295 2, C514-20

Kuboki, Satoshi; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B 2008. Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 48 4, 1213-23

Kuboki, Satoshi; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Zingarelli, Basilia; Lentsch, Alex B 2008. Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. Hepatology (Baltimore, Md.), 47 1, 215-24

Martignoni, André; Tschöp, Johannes; Goetzman, Holly S; Choi, Lisa G; Reid, Maria D; Johannigman, Jay A; Lentsch, Alex B; Caldwell, Charles C 2008. CD4-expressing cells are early mediators of the innate immune system during sepsis. Shock (Augusta, Ga.), 29 5, 591-7

Shin, Thomas; Kuboki, Satoshi; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Pritts, Timothy A; Lentsch, Alex B 2008. Activation of peroxisome proliferator-activated receptor-gamma during hepatic ischemia is age-dependent. The Journal of surgical research, 147 2, 200-5

Shin, Thomas; Kuboki, Satoshi; Lentsch, Alex B 2008. Roles of nuclear factor-kappaB in postischemic liver. Hepatology research : the official journal of the Japan Society of Hepatology, 38 5, 429-40

Tschöp, Johannes; Martignoni, André; Goetzman, Holly S; Choi, Lisa G; Wang, Quan; Noel, John G; Ogle, Cora K; Pritts, Timothy A; Johannigman, Jay A; Lentsch, Alex B; Caldwell, Charles C 2008. Gammadelta T cells mitigate the organ injury and mortality of sepsis. Journal of leukocyte biology, 83 3, 581-8

Caldwell, Charles C; Tschoep, Johannes; Lentsch, Alex B 2007. Lymphocyte function during hepatic ischemia/reperfusion injury. Journal of leukocyte biology, 82 3, 457-64

Caldwell,C.C.; Tschoep,J.; Lentsch,A.B. 2007. Lymphocyte function during hepatic ischemia/reperfusion injury Journal of Leukocyte Biology, 82 3, 457

Kuboki, Satoshi; Okaya, Tomohisa; Schuster, Rebecca; Blanchard, John; Denenberg, Alvin; Wong, Hector R; Lentsch, Alex B 2007. Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia. American journal of physiology. Gastrointestinal and liver physiology, 292 1, G201-7

Kuboki, Satoshi; Schuster, Rebecca; Blanchard, John; Pritts, Timothy A; Wong, Hector R; Lentsch, Alex B 2007. Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice. American journal of physiology. Gastrointestinal and liver physiology, 292 4, G1141-9

Kuboki,S.; Okaya,T.; Schuster,R.; Blanchard,J.; Denenberg,A.; Wong,H.R.; Lentsch,A.B. 2007. Hepatocyte nf-κb activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia American Journal of Physiology - Gastrointestinal and Liver Physiology, 292 1, G201

Kuboki,S.; Schuster,R.; Blanchard,J.; Pritts,T.A.; Wong,H.R.; Lentsch,A.B. 2007. Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice American Journal of Physiology - Gastrointestinal and Liver Physiology, 292 4, G1141

Lentsch, Alex B; Pathrose, Peterson; Kader, Sarah; Kuboki, Satoshi; Collins, Margaret H; Waltz, Susan E 2007. The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation. Shock (Augusta, Ga.), 27 3, 274-80

Lentsch,A.B.; Pathrose,P.; Kader,S.; Kuboki,S.; Collins,M.H.; Waltz,S.E. 2007. The ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor κb activation Shock, 27 3, 274

Saari, Jack T; Wold, Loren E; Duan, Jinhong; Ren, Jun; Carlson, Hanqian L; Bode, Ann M; Lentsch, Alex B; Zeng, Huawei; Schuschke, Dale A 2007. Cardiac nitric oxide synthases are elevated in dietary copper deficiency. The Journal of nutritional biochemistry, 18 7, 443-8

Saari,J.T.; Wold,L.E.; Duan,J.; Ren,J.; Carlson,H.L.; Bode,A.M.; Lentsch,A.B.; Zeng,H.; Schuschke,D.A. 2007. Cardiac nitric oxide synthases are elevated in dietary copper deficiency Journal of Nutritional Biochemistry, 18 7, 443

Solomkin, Joseph S; Robinson, Chad T; Cave, Cynthia M; Ehmer, Birgit; Lentsch, Alex B 2007. Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production. Shock (Augusta, Ga.), 28 3, 334-8

Solomkin,J.S.; Robinson,C.T.; Cave,C.M.; Ehmer,B.; Lentsch,A.B. 2007. Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production Shock, 28 3, 334

Thiel, Manfred; Caldwell, Charles C; Kreth, Simone; Kuboki, Satoshi; Chen, P; Smith, Patrick; Ohta, Akio; Lentsch, Alex B; Lukashev, Dmitry; Sitkovsky, Michail V 2007. Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival. PloS one, 2 9, e853

Husted, T L; Blanchard, J; Schuster, R; Shen, H; Lentsch, A B 2006. Potential role for IL-23 in hepatic ischemia/reperfusion injury. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 55 5, 177-8

Husted, Thomas L; Lentsch, Alex B 2006. The role of cytokines in pharmacological modulation of hepatic ischemia/reperfusion injury. Current pharmaceutical design, 12 23, 2867-73

Husted,T.L.; Blanchard,J.; Schuster,R.; Shen,H.; Lentsch,A.B. 2006. Potential role for il-23 in hepatic ischemia/reperfusion injury Inflammation Research, 55 5, 177

Husted,T.L.; Lentsch,A.B. 2006. The role of cytokines in pharmacological modulation of hepatic ischemia/reperfusion injury Current Pharmaceutical Design, 12 23, 2867

Lentsch, Alex B 2006. CXC chemokines and prostate cancer: growth regulators and potential biomarkers. Future oncology (London, England), 2 5, 651-8

Lentsch,A.B. 2006. Cxc chemokines and prostate cancer: growth regulators and potential biomarkers Future Oncology, 2 5, 651

Mallakin, Ali; Kutcher, Louis W; McDowell, Susan A; Kong, Sue; Schuster, Rebecca; Lentsch, Alex B; Aronow, Bruce J; Leikauf, George D; Waltz, Susan E 2006. Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. American journal of respiratory cell and molecular biology, 34 1, 15-27

Mallakin,A.; Kutcher,L.W.; McDowell,S.A.; Kong,S.; Schuster,R.; Lentsch,A.B.; Aronow,B.J.; Leikauf,G.D.; Waltz,S.E. 2006. Gene expression profiles of mst1r-deficient mice during nickel-induced acute lung injury American Journal of Respiratory Cell and Molecular Biology, 34 1, 15

Shen, Hui; Schuster, Rebecca; Lu, Bao; Waltz, Susan E; Lentsch, Alex B 2006. Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth. The Prostate, 66 16, 1721-8

Shen, Hui; Schuster, Rebecca; Stringer, Keith F; Waltz, Susan E; Lentsch, Alex B 2006. The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 1, 59-64

Shen,H.; Schuster,R.; Lu,B.; Waltz,S.E.; Lentsch,A.B. 2006. Critical and opposing roles of the chemokine receptors cxcr2 and cxcr3 in prostate tumor growth Prostate, 66 16, 1721

Shen,H.; Schuster,R.; Stringer,K.F.; Waltz,S.E.; Lentsch,A.B. 2006. The duffy antigen/receptor for chemokines (darc) regulates prostate tumor growth FASEB Journal, 20 1, 59

Solomkin, Joseph S; Robinson, Chad T; Cave, Cynthia M; Umanskiy, Konstantin; Matlin, Karl; Williams, Mark A; Lentsch, Alex B 2006. Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space. Shock (Augusta, Ga.), 25 5, 440-5

Solomkin,J.S.; Robinson,C.T.; Cave,C.M.; Umanskiy,K.; Matlin,K.; Williams,M.A.; Lentsch,A.B. 2006. Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space Shock, 25 5, 440

Toledo-Pereyra,L.H.; Lopez-Neblina,F.; Lentsch,A.B.; Anaya-Prado,R.; Romano,S.J.; Ward,P.A. 2006. Selectin inhibition modulates nf-κb and ap-1 signaling after liver ischemia/reperfusion Journal of Investigative Surgery, 19 5, 313

Barone, Sharon; Okaya, Tomohisa; Rudich, Steve; Petrovic, Snezana; Tenrani, Kathy; Wang, Zhaohui; Zahedi, Kamyar; Casero, Robert A; Lentsch, Alex B; Soleimani, Manoocher 2005. Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury. American journal of physiology. Cell physiology, 289 4, C826-35

Barone,S.; Okaya,T.; Rudich,S.; Petrovic,S.; Tenrani,K.; Wang,Z.; Zahedi,K.; Casero,R.A.; Lentsch,A.B.; Soleimani,M. 2005. Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury American Journal of Physiology - Cell Physiology, 289 4 58-4, C826

Caldwell, Charles C; Okaya, Tomohisa; Martignoni, Andre; Husted, Thomas; Schuster, Rebecca; Lentsch, Alex B 2005. Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion. American journal of physiology. Gastrointestinal and liver physiology, 289 5, G969-76

Caldwell,C.C.; Okaya,T.; Martignoni,A.; Husted,T.; Schuster,R.; Lentsch,A.B. 2005. Divergent functions of cd4+ t lymphocytes in acute liver inflammation and injury after ischemia-reperfusion American Journal of Physiology - Gastrointestinal and Liver Physiology, 289 5 52-5, G969

Gordon, Sharon A; Lominadze, David; Saari, Jack T; Lentsch, Alex B; Schuschke, Dale A 2005. Impaired deformability of copper-deficient neutrophils. Experimental biology and medicine (Maywood, N.J.), 230 8, 543-8

Gordon,S.A.; Lominadze,D.; Saari,J.T.; Lentsch,A.B.; Schuschke,D.A. 2005. Impaired deformability of copper-deficient neutrophils Experimental Biology and Medicine, 230 8, 543

Husted, Thomas L; Govindaswami, Meera; Oeltgen, Peter R; Rudich, Steven M; Lentsch, Alex B 2005. A delta2-opioid agonist inhibits p38 MAPK and suppresses activation of murine macrophages. The Journal of surgical research, 128 1, 45-9

Husted, Thomas L; Lentsch, Alex B 2005. Anti-inflammatory approaches to the prevention of ischemia/reperfusion injury in solid organ transplantation. Current opinion in investigational drugs (London, England : 2000), 6 5, 508-12

Husted,T.L.; Govindaswami,M.; Oeltgen,P.R.; Rudich,S.M.; Lentsch,A.B. 2005. A δ2-opioid agonist inhibits p38 mapk and suppresses activation of murine macrophages Journal of Surgical Research, 128 1, 45

Husted,T.L.; Lentsch,A.B. 2005. Anti-inflammatory approaches to the prevention of ischemia/reperfusion injury in solid organ transplantation Current Opinion in Investigational Drugs, 6 5, 508

Lentsch, Alex B 2005. Activation and function of hepatocyte NF-kappaB in postischemic liver injury. Hepatology (Baltimore, Md.), 42 1, 216-8

Mayhew, Christopher N; Bosco, Emily E; Fox, Sejal R; Okaya, Tomohisa; Tarapore, Pheruza; Schwemberger, Sandy J; Babcock, George F; Lentsch, Alex B; Fukasawa, Kenji; Knudsen, Erik S 2005. Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy. Cancer research, 65 11, 4568-77

Mayhew,C.N.; Bosco,E.E.; Fox,S.R.; Okaya,T.; Tarapore,P.; Schwemberger,S.J.; Babcock,G.F.; Lentsch,A.B.; Fukasawa,K.; Knudsen,E.S. 2005. Liver-specific prb loss results in ectopic cell cycle entry and aberrant ploidy Cancer Research, 65 11, 4568

Okaya, Tomohisa; Blanchard, John; Schuster, Rebecca; Kuboki, Satoshi; Husted, Thomas; Caldwell, Charles C; Zingarelli, Basilia; Wong, Hector; Solomkin, Joseph S; Lentsch, Alex B 2005. Age-dependent responses to hepatic ischemia/reperfusion injury. Shock (Augusta, Ga.), 24 5, 421-7

Okaya, Tomohisa; Lentsch, Alex B 2005. Hepatic expression of S32A/S36A IkappaBalpha does not reduce postischemic liver injury. The Journal of surgical research, 124 2, 244-9

Okaya,T.; Blanchard,J.; Schuster,R.; Kuboki,S.; Husted,T.; Caldwell,C.C.; Zingarelli,B.; Wong,H.; Solomkin,J.S.; Lentsch,A.B. 2005. Age-dependent responses to hepatic ischemia/reperfusion injury Shock, 24 5, 421

Okaya,T.; Lentsch,A.B. 2005. Hepatic expression of s32a/s36a iκbα does not reduce postischemic liver injury Journal of Surgical Research, 124 2, 244

Thakar, Charuhas V; Zahedi, Kamyar; Revelo, Monica P; Wang, Zhaohui; Burnham, Charles E; Barone, Sharon; Bevans, Shannon; Lentsch, Alex B; Rabb, Hamid; Soleimani, Manoocher 2005. Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia. The Journal of clinical investigation, 115 12, 3451-9

Thakar,C.V.; Zahedi,K.; Revelo,M.P.; Wang,Z.; Burnham,C.E.; Barone,S.; Bevans,S.; Lentsch,A.B.; Rabb,H.; Soleimani,M. 2005. Identification of thrombospondin 1 (tsp-1) as a novel mediator of cell injury in kidney ischemia Journal of Clinical Investigation, 115 12, 3451

Williams, Mark A; Cave, Cindy M; Quaid, Gina; Robinson, Chad; Daly, Thomas J; Witt, Dan; Lentsch, Alex B; Solomkin, Joseph S 2005. Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production. Shock (Augusta, Ga.), 23 4, 371-6

Williams,M.A.; Cave,C.M.; Quaid,G.; Robinson,C.; Daly,T.J.; Witt,D.; Lentsch,A.B.; Solomkin,J.S. 2005. Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production Shock, 23 4, 371

Okaya, T; Holthaus, R; Kato, A; Lentsch, A B 2004. Involvement of the neuropeptide substance P in lung inflammation induced by hepatic ischemia/reperfusion. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 53 6, 257-61

Okaya, Tomohisa; Lentsch, Alex B 2004. Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury. American journal of physiology. Gastrointestinal and liver physiology, 286 4, G606-12

Okaya,T.; Holthaus,R.; Kato,A.; Lentsch,A.B. 2004. Involvement of the neuropeptide substance p in lung inflammation induced by hepatic ischemia/reperfusion Inflammation Research, 53 6, 257

Okaya,T.; Lentsch,A.B. 2004. Peroxisome proliferator-activated receptor-α regulates postischemic liver injury American Journal of Physiology - Gastrointestinal and Liver Physiology, 286 4 49-4, G606

Shen, Hui; Lentsch, Alex B 2004. Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines. American journal of physiology. Cell physiology, 286 4, C840-7

Shen,H.; Lentsch,A.B. 2004. Progressive dysregulation of transcription factors nf-κb and stat1 in prostate cancer cells causes proangiogenic production of cxc chemokines American Journal of Physiology - Cell Physiology, 286 4 55-4, C840

Kato, Atsushi; Okaya, Tomohisa; Lentsch, Alex B 2003. Endogenous IL-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury. Hepatology (Baltimore, Md.), 37 2, 304-12

Kato,A.; Okaya,T.; Lentsch,A.B. 2003. Endogenous il-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury Hepatology, 37 2, 304

Okaya,T.; Lentsch,A.B. 2003. Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion Journal of Investigative Surgery, 16 3, 141

Umanskiy, Konstantin; Robinson, Chad; Cave, Cindy; Williams, Mark A; Lentsch, Alex B; Cuschieri, Joseph; Solomkin, Joseph S 2003. NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery, 134 2, 378-83

Umanskiy,K.; Robinson,C.; Cave,C.; Williams,M.A.; Lentsch,A.B.; Cuschieri,J.; Solomkin,J.S. 2003. Nadph oxidase activation in fibronectin adherent human neutrophils: a potential role for β1 integrin ligation Surgery, 134 2, 378

Anaya-Prado, Roberto; Toledo-Pereyra, Luis H; Lentsch, Alex B; Ward, Peter A 2002. Ischemia/reperfusion injury. The Journal of surgical research, 105 2, 248-58

Anaya-Prado,R.; Toledo-Pereyra,L.H.; Lentsch,A.B.; Ward,P.A. 2002. Ischemia/reperfusion injury Journal of Surgical Research, 105 2, 248

Guo, Ren-Feng; Lentsch, Alex B; Sarma, J Vidya; Sun, Lei; Riedemann, Niels C; McClintock, Shannon D; McGuire, Stephanie R; Van Rooijen, Nico; Ward, Peter A 2002. Activator protein-1 activation in acute lung injury. The American journal of pathology, 161 1, 275-82

Guo,R.-F.; Lentsch,A.B.; Sarma,J.V.; Sun,L.; Riedemann,N.C.; McClintock,S.D.; McGuire,S.R.; Van Rooijen,N.; Ward,P.A. 2002. Activator protein-1 activation in acute lung injury American Journal of Pathology, 161 1, 275

Kato, Atsushi; Edwards, Michael J; Lentsch, Alex B 2002. Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion. Journal of hepatology, 37 1, 48-55

Kato, Atsushi; Gabay, Cem; Okaya, Tomohisa; Lentsch, Alex B 2002. Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion. The American journal of pathology, 161 5, 1797-803

Kato, Atsushi; Graul-Layman, Amanda; Edwards, Michael J; Lentsch, Alex B 2002. Promotion of hepatic ischemia/reperfusion injury by IL-12 is independent of STAT4. Transplantation, 73 7, 1142-5

Kato, Atsushi; Singh, Saurabh; McLeish, Kenneth R; Edwards, Michael J; Lentsch, Alex B 2002. Mechanisms of hypothermic protection against ischemic liver injury in mice. American journal of physiology. Gastrointestinal and liver physiology, 282 4, G608-16

Kato,A.; Edwards,M.J.; Lentsch,A.B. 2002. Gene deletion of nf-κb p50 does not alter the hepatic inflammatory response to ischemia/reperfusion Journal of Hepatology, 37 1, 48

Kato,A.; Gabay,C.; Okaya,T.; Lentsch,A.B. 2002. Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion American Journal of Pathology, 161 5, 1797

Kato,A.; Graul-Layman,A.; Edwards,M.J.; Lentsch,A.B. 2002. Promotion of hepatic ischemia/reperfusion injury by il-12 is independent of stat4 Transplantation, 73 7, 1142

Kato,A.; Singh,S.; McLeish,K.R.; Edwards,M.J.; Lentsch,A.B. 2002. Mechanisms of hypothermic protection against ischemic liver injury in mice American Journal of Physiology - Gastrointestinal and Liver Physiology, 282 4 45-4, G608

Lentsch, Alex B 2002. The Duffy antigen/receptor for chemokines (DARC) and prostate cancer. A role as clear as black and white? FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 16 9, 1093-5

Lentsch,A.B. 2002. The duffy antigen/receptor for chemokines (darc) and prostate cancer. a role as clear as black and white? FASEB Journal, 16 9, 1093

Schuschke, Dale A; Percival, Susan S; Lominadze, David; Saari, Jack T; Lentsch, Alex B 2002. Tissue-specific ICAM-1 expression and neutrophil transmigration in the copper-deficient rat. Inflammation, 26 6, 297-303

Schuschke,D.A.; Percival,S.S.; Lominadze,D.; Saari,J.T.; Lentsch,A.B. 2002. Tissue-specific icam-1 expression and neutrophil transmigration in the copper-deficient rat Inflammation, 26 6, 297

Ward,P.A.; Lentsch,A.B. 2002. Endogenous regulation of the acute inflammatory response Molecular and Cellular Biochemistry, 234-235 , 225

Godshall, C J; Lentsch, A B; Peyton, J C; Scott, M J; Cheadle, W G 2001. STAT4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis. Clinical and diagnostic laboratory immunology, 8 6, 1044-8

Godshall,C.J.; Lentsch,A.B.; Peyton,J.C.; Scott,M.J.; Cheadle,W.G. 2001. Stat4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis Clinical and Diagnostic Laboratory Immunology, 8 6, 1044

Guo, R F; Lentsch, A B; Warner, R L; Huber-Lang, M; Sarma, J V; Hlaing, T; Shi, M M; Lukacs, N W; Ward, P A 2001. Regulatory effects of eotaxin on acute lung inflammatory injury. Journal of immunology (Baltimore, Md. : 1950), 166 8, 5208-18

Guo,R.-F.; Lentsch,A.B.; Warner,R.L.; Huber-Lang,M.; Sarma,J.V.; Hlaing,T.; Shi,M.M.; Lukacs,N.W.; Ward,P.A. 2001. Regulatory effects of eotaxin on acute lung inflammatory injury Journal of Immunology, 166 8, 5208

Lentsch, A B; Kato, A; Davis, B; Wang, W; Chao, C; Edwards, M J 2001. STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia. The Journal of clinical investigation, 108 10, 1475-82

Lentsch, A B; Kato, A; Saari, J T; Schuschke, D A 2001. Augmented metalloproteinase activity and acute lung injury in copper-deficient rats. American journal of physiology. Lung cellular and molecular physiology, 281 2, L387-93

Lentsch, A B; Ward, P A 2001. Regulation of experimental lung inflammation. Respiration physiology, 128 1, 17-22

Lentsch,A.B.; Kato,A.; Davis,B.; Wang,W.; Chao,C.; Edwards,M.J. 2001. Stat4 and stat6 regulate systemic inflammation and protect against lethal endotoxemia Journal of Clinical Investigation, 108 10, 1475

Lentsch,A.B.; Kato,A.; Saari,J.T.; Schuschke,D.A. 2001. Augmented metalloproteinase activity and acute lung injury in copper-deficient rats American Journal of Physiology - Lung Cellular and Molecular Physiology, 281 2 25-2, L387

Lentsch,A.B.; Ward,P.A. 2001. Regulation of experimental lung inflammation Respiration Physiology, 128 1, 17

Bless, N M; Huber-Lang, M; Guo, R F; Warner, R L; Schmal, H; Czermak, B J; Shanley, T P; Crouch, L D; Lentsch, A B; Sarma, V; Mulligan, M S; Friedl, H P; Ward, P A 2000. Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats. Journal of immunology (Baltimore, Md. : 1950), 164 5, 2650-9

Bless,N.M.; Huber-Lang,M.; Guo,R.-F.; Warner,R.L.; Schmal,H.; Czermak,B.J.; Shanley,T.P.; Crouch,L.D.; Lentsch,A.B.; Sarma,V.; Mulligan,M.S.; Friedl,H.P.; Ward,P.A. 2000. Role of cc chemokines (macrophage inflammatory protein-1β, monocyte chemoattractant protein-1, rantes) in acute lung injury in rats Journal of Immunology, 164 5, 2650

Dawson, T C; Lentsch, A B; Wang, Z; Cowhig, J E; Rot, A; Maeda, N; Peiper, S C 2000. Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC). Blood, 96 5, 1681-4

Dawson,T.C.; Lentsch,A.B.; Wang,Z.; Cowhig,J.E.; Rot,A.; Maeda,N.; Peiper,S.C. 2000. Exaggerated response to endotoxin in mice lacking the duffy antigen/receptor for chemokines (darc) Blood, 96 5, 1681

Kato, A; Yoshidome, H; Edwards, M J; Lentsch, A B 2000. Reduced hepatic ischemia/reperfusion injury by IL-4: potential anti-inflammatory role of STAT6. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 49 6, 275-9

Kato, A; Yoshidome, H; Edwards, M J; Lentsch, A B 2000. Regulation of liver inflammatory injury by signal transducer and activator of transcription-6. The American journal of pathology, 157 1, 297-302

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. 2000. Reduced hepatic ischemia/reperfusion injury by il-4: potential anti- inflammatory role of stat6 Inflammation Research, 49 6, 275

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. 2000. Regulation of liver inflammatory injury by signal transducer and activator of transcription-6 American Journal of Pathology, 157 1, 297

Lentsch, A B; Kato, A; Yoshidome, H; McMasters, K M; Edwards, M J 2000. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology (Baltimore, Md.), 32 2, 169-73

Lentsch, A B; Ward, P A 2000. Regulation of inflammatory vascular damage. The Journal of pathology, 190 3, 343-8

Lentsch, A B; Ward, P A 2000. The NFkappaBb/IkappaB system in acute inflammation. Archivum immunologiae et therapiae experimentalis, 48 2, 59-63

Lentsch,A.B. 2000. Regulation of acute inflammation by the duffy antigen/ receptor for chemokines (darc): exaggerated response to lps in knockout mice and protection in transgenic mice programmed for endothelial expression Blood, 96 11 PART I,

Lentsch,A.B.; Kato,A.; Yoshidome,H.; McMasters,K.M.; Edwards,M.J. 2000. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury Hepatology, 32 2, 169

Lentsch,A.B.; Ward,P.A. 2000. Regulation of inflammatory vascular damage Journal of Pathology, 190 3, 343

Lentsch,A.B.; Ward,P.A. 2000. The nfκb/iκb system in acute inflammation Archivum Immunologiae et Therapiae Experimentalis, 48 2, 59

Molestina, R E; Miller, R D; Lentsch, A B; Ramirez, J A; Summersgill, J T 2000. Requirement for NF-kappaB in transcriptional activation of monocyte chemotactic protein 1 by Chlamydia pneumoniae in human endothelial cells. Infection and immunity, 68 7, 4282-8

Molestina,R.E.; Miller,R.D.; Lentsch,A.B.; Ramirez,J.A.; Summersgill,J.T. 2000. Requirement for nf-κb in transcriptional activation of monocyte chemotactic protein 1 by chlamydia pneumoniae in human endothelial cells Infection and Immunity, 68 7, 4282

Mulligan, M S; Lentsch, A B; Huber-Lang, M; Guo, R F; Sarma, V; Wright, C D; Ulich, T R; Ward, P A 2000. Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor. The American journal of pathology, 156 3, 1033-9

Mulligan,M.S.; Lentsch,A.B.; Huber-Lang,M.; Guo,R.-F.; Sarma,V.; Wright,C.D.; Ulich,T.R.; Ward,P.A. 2000. Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor American Journal of Pathology, 156 3, 1033

Yoshidome, H; Miyazaki, M; Shimizu, H; Ito, H; Nakagawa, K; Ambiru, S; Nakajima, N; Edwards, M J; Lentsch, A B 2000. Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion. Journal of hepatology, 33 1, 59-67

Yoshidome,H.; Miyazaki,M.; Shimizu,H.; Ito,H.; Nakagawa,K.; Ambiru,S.; Nakajima,N.; Edwards,M.J.; Lentsch,A.B. 2000. Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion Journal of Hepatology, 33 1, 59

Bless, N M; Warner, R L; Padgaonkar, V A; Lentsch, A B; Czermak, B J; Schmal, H; Friedl, H P; Ward, P A 1999. Roles for C-X-C chemokines and C5a in lung injury after hindlimb ischemia-reperfusion. The American journal of physiology, 276 1 Pt 1, L57-63

Bless,N.M.; Waener,R.L.; Padgaonkar,V.A.; Lentsch,A.B.; Czermak,B.J.; Schmal,H.; Friedl,H.P.; Ward,P.A. 1999. Roles for c-x-c chemokines and c5a in lung injury after hindlimb ischemia-reperfusion American Journal of Physiology - Lung Cellular and Molecular Physiology, 276 1 20-1, L57

Czermak, B J; Lentsch, A B; Bless, N M; Schmal, H; Friedl, H P; Ward, P A 1999. Synergistic enhancement of chemokine generation and lung injury by C5a or the membrane attack complex of complement. The American journal of pathology, 154 5, 1513-24

Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Schmal,H.; Friedl,H.P.; Ward,P.A. 1999. Synergistic enhancement of chemokine generation and lung injury by c5a or the membrane attack complex of complement American Journal of Pathology, 154 5, 1513

Lentsch, A B; Crouch, L D; Jordan, J A; Czermak, B J; Yun, E C; Guo, R; Sarma, V; Diehl, K M; Ward, P A 1999. Regulatory effects of interleukin-11 during acute lung inflammatory injury. Journal of leukocyte biology, 66 1, 151-7

Lentsch, A B; Czermak, B J; Bless, N M; Van Rooijen, N; Ward, P A 1999. Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB. American journal of respiratory cell and molecular biology, 20 4, 692-8

Lentsch, A B; Czermak, B J; Jordan, J A; Ward, P A 1999. Regulation of acute lung inflammatory injury by endogenous IL-13. Journal of immunology (Baltimore, Md. : 1950), 162 2, 1071-6

Lentsch, A B; Jordan, J A; Czermak, B J; Diehl, K M; Younkin, E M; Sarma, V; Ward, P A 1999. Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation. The American journal of pathology, 154 1, 239-47

Lentsch, A B; Miller, F N; Edwards, M J 1999. Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2. Cancer immunology, immunotherapy : CII, 47 5, 243-8

Lentsch, A B; Ward, P A 1999. Activation and regulation of NFkappaB during acute inflammation. Clinical chemistry and laboratory medicine : CCLM / FESCC, 37 3, 205-8

Lentsch, A B; Yoshidome, H; Kato, A; Warner, R L; Cheadle, W G; Ward, P A; Edwards, M J 1999. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice. Hepatology (Baltimore, Md.), 30 6, 1448-53

Lentsch, A B; Yoshidome, H; Warner, R L; Ward, P A; Edwards, M J 1999. Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion. Gastroenterology, 117 4, 953-61

Lentsch, Alex B.; Ward, Peter A. 1999. Understanding the Pathogenesis of Inflammation Using Rodent Models: Identification of a Transcription Factor (NFkappaB) Necessary for Development of Inflammatory Injury. ILAR journal / National Research Council, Institute of Laboratory Animal Resources, 40 4, 151-156

Lentsch,A.B.; Crouch,L.D.; Jordan,J.A.; Czermak,B.J.; Yun,E.C.; Renfeng,G.; Sarma,V.; Diehl,K.M.; Ward,P.A. 1999. Regulatory effects of interleukin-11 during acute lung inflammatory injury Journal of Leukocyte Biology, 66 1, 151

Lentsch,A.B.; Czermak,B.J.; Bless,N.M.; Van Rooijen,N.; Ward,P.A. 1999. Essential role of alveolar macrophages in intrapulmonary activation of nf-κb American Journal of Respiratory Cell and Molecular Biology, 20 4, 692

Lentsch,A.B.; Czermak,B.J.; Jordan,J.A.; Ward,P.A. 1999. Regulation of acute lung inflammatory injury by endogenous il-13 Journal of Immunology, 162 2, 1071

Lentsch,A.B.; Jordan,J.A.; Czermak,B.J.; Diehl,K.M.; Younkin,E.M.; Sarma,V.; Ward,P.A. 1999. Inhibition of nf-κb activation and augmentation of iκbβ by secretory leukocyte protease inhibitor during lung inflammation American Journal of Pathology, 154 1, 239

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. 1999. Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2 Cancer Immunology Immunotherapy, 47 5, 243

Lentsch,A.B.; Ward,P.A. 1999. Activation and regulation of nfκb during acute inflammation Clinical Chemistry and Laboratory Medicine, 37 3, 205

Lentsch,A.B.; Ward,P.A. 1999. Understanding the pathogenesis of inflammation using rodent models: identification of a transcription factor (nfκb) necessary for development of inflammatory injury ILAR Journal, 40 4, 151

Lentsch,A.B.; Yoshidome,H.; Kato,A.; Warner,R.L.; Cheadle,W.G.; Ward,P.A.; Edwards,M.J. 1999. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice Hepatology, 30 6, 1448

Lentsch,A.B.; Yoshidome,H.; Warner,R.L.; Ward,P.A.; Edwards,M.J. 1999. Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion Gastroenterology, 117 4, 953

Ward, P A; Lentsch, A B 1999. The acute inflammatory response and its regulation. Archives of surgery (Chicago, Ill. : 1960), 134 6, 666-9

Ward,P.A.; Lentsch,A.B. 1999. The acute inflammatory response and its regulation Archives of Surgery, 134 6, 666

Yoshidome, H; Kato, A; Edwards, M J; Lentsch, A B 1999. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB. Hepatology (Baltimore, Md.), 30 1, 203-8

Yoshidome, H; Kato, A; Edwards, M J; Lentsch, A B 1999. Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia-reperfusion. The American journal of physiology, 277 5 Pt 1, L919-23

Yoshidome, H; Kato, A; Miyazaki, M; Edwards, M J; Lentsch, A B 1999. IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion. The American journal of pathology, 155 4, 1059-64

Yoshidome, H; Lentsch, A B; Cheadle, W G; Miller, F N; Edwards, M J 1999. Enhanced pulmonary expression of CXC chemokines during hepatic ischemia/reperfusion-induced lung injury in mice. The Journal of surgical research, 81 1, 33-7

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. 1999. Interleukin-10 inhibits pulmonary nf-κb activation and lung injury induced by hepatic ischemia-reperfusion American Journal of Physiology - Lung Cellular and Molecular Physiology, 277 5 21-5, L919

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. 1999. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor κb Hepatology, 30 1, 203

Yoshidome,H.; Kato,A.; Miyazaki,M.; Edwards,M.J.; Lentsch,A.B. 1999. Il-13 activates stat6 and inhibits liver injury induced by ischemia/reperfusion American Journal of Pathology, 155 4, 1059

Yoshidome,H.; Lentsch,A.B.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. 1999. Enhanced pulmonary expression of cxc chemokines during hepatic ischemia/reperfusion-induced lung injury in mice Journal of Surgical Research, 81 1, 33

Bless, N M; Tojo, S J; Kawarai, H; Natsume, Y; Lentsch, A B; Padgaonkar, V A; Czermak, B J; Schmal, H; Friedl, H P; Ward, P A 1998. Differing patterns of P-selectin expression in lung injury. The American journal of pathology, 153 4, 1113-22

Bless,N.M.; Tojo,S.J.; Kawarai,H.; Natsume,Y.; Lentsch,A.B.; Padgaonkar,V.A.; Czermak,B.J.; Schmal,H.; Friedl,H.P.; Ward,P.A. 1998. Differing patterns of p-selectin expression in lung injury American Journal of Pathology, 153 4, 1113

Czermak, B J; Lentsch, A B; Bless, N M; Schmal, H; Friedl, H P; Ward, P A 1998. Role of complement in in vitro and in vivo lung inflammatory reactions. Journal of leukocyte biology, 64 1, 40-8

Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Schmal,H.; Friedl,H.P.; Ward,P.A. 1998. Role of complement in in vitro and in vivo lung inflammatory reactions Journal of Leukocyte Biology, 64 1, 40

Lentsch, A B; Czermak, B J; Bless, N M; Ward, P A 1998. NF-kappaB activation during IgG immune complex-induced lung injury: requirements for TNF-alpha and IL-1beta but not complement. The American journal of pathology, 152 5, 1327-36

Lentsch, A B; Edwards, M J; Sims, D E; Miller, F N 1998. N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2. Journal of leukocyte biology, 63 1, 22-30

Lentsch, A B; Yoshidome, H; Cheadle, W G; Miller, F N; Edwards, M J 1998. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC. Hepatology (Baltimore, Md.), 27 4, 1172-7

Lentsch, A B; Yoshidome, H; Cheadle, W G; Miller, F N; Edwards, M J 1998. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and Kupffer cells. Hepatology (Baltimore, Md.), 27 2, 507-12

Lentsch,A.B.; Bless,N.M.; Czermak,B.J.; Ward,P.A. 1998. Determinants of nf-κb activation in acute lung injury FASEB Journal, 12 5,

Lentsch,A.B.; Czermak,B.J.; Bless,N.M.; Ward,P.A. 1998. Nf-κb activation during igg immune complex-induced lung injury: requirements for tnf-α and il-1β but not complement American Journal of Pathology, 152 5, 1327

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Miller,F.N. 1998. Nw-nitro-l-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2 Journal of Leukocyte Biology, 63 1, 22

Lentsch,A.B.; Yoshidome,H.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. 1998. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and kupffer cells Hepatology, 27 2, 507

Mulligan, M S; Lentsch, A B; Miyasaka, M; Ward, P A 1998. Cytokine and adhesion molecule requirements for neutrophil recruitment during glycogen-induced peritonitis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 47 6, 251-5

Mulligan, M S; Lentsch, A B; Shanley, T P; Miyasaka, M; Johnson, K J; Ward, P A 1998. Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody. Inflammation, 22 4, 403-17

Mulligan, M S; Lentsch, A B; Ward, P A 1998. In vivo recruitment of neutrophils: consistent requirements for L-arginine and variable requirements for complement and adhesion molecules. Inflammation, 22 3, 327-39

Mulligan,M.S.; Lentsch,A.B.; Miyasaka,M.; Ward,P.A. 1998. Cytokine and adhesion molecule requirements for neutrophil recruitment during glycogen-induced peritonitis Inflammation Research, 47 6, 251

Mulligan,M.S.; Lentsch,A.B.; Shanley,T.P.; Miyasaka,M.; Johnson,K.J.; Ward,P.A. 1998. Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody Inflammation, 22 4, 403

Mulligan,M.S.; Lentsch,A.B.; Ward,P.A. 1998. In vivo recruitment of neutrophils: consistent requirements for l-arginine and variable requirements for complement and adhesion molecules Inflammation, 22 3, 327

Schmal, H; Czermak, B J; Lentsch, A B; Bless, N M; Beck-Schimmer, B; Friedl, H P; Ward, P A 1998. Soluble ICAM-1 activates lung macrophages and enhances lung injury. Journal of immunology (Baltimore, Md. : 1950), 161 7, 3685-93

Schmal,H.; Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Beck-Schimmer,B.; Friedl,H.P.; Ward,P.A. 1998. Soluble icam-1 activates lung macrophages and enhances lung injury Journal of Immunology, 161 7, 3685

Crouch,L.D.; Lentsch,A.B.; Warner,R.L.; Johnson,K.J.; Ward,P.A. 1997. Regulatory effects of adrenal gland products in igg immune complex acute lung injury FASEB Journal, 11 3,

Lentsch, A B; Miller, F N; Edwards, M J 1997. Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation. The American journal of physiology, 272 4 Pt 1, G727-31

Lentsch, A B; Nakagawa, K; Yoshidome, H; Gerassimides, A; Miller, F N; Edwards, M J 1997. Distinct biological activities of recombinant forms of human interleukin-2 in vivo. Cancer immunology, immunotherapy : CII, 43 6, 331-6

Lentsch, A B; Shanley, T P; Sarma, V; Ward, P A 1997. In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13. The Journal of clinical investigation, 100 10, 2443-8

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. 1997. Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation American Journal of Physiology - Gastrointestinal and Liver Physiology, 272 4 35-4, G727

Lentsch,A.B.; Nakagawa,K.; Yoshidome,H.; Gerassimides,A.; Miller,F.N.; Edwards,M.J. 1997. Distinct biologisal activities of recombinant forms of human interleukin-2 in vivo Cancer Immunology Immunotherapy, 43 6, 331

Lentsch,A.B.; Shanley,T.P.; Sarma,V.; Ward,P.A. 1997. In vivo suppression of nf-κb and preservation of iκbα by interleukin- 10 and interleukin-13 Journal of Clinical Investigation, 100 10, 2443

Lentsch,A.B.; Shanley,T.P.; Ward,P.A. 1997. Interleukin-10 protects against igg immune complex-induced lung injury through suppression of nf-κb FASEB Journal, 11 3,

Anderson, J A; Lentsch, A B; Hadjiminas, D J; Miller, F N; Martin, A W; Nakagawa, K; Edwards, M J 1996. The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in C57BL/6 mice. The Journal of clinical investigation, 97 8, 1952-9

Anderson,J.A.; Lentsch,A.B.; Hadjiminas,D.J.; Miller,F.N.; Martin,A.W.; Nakagawa,K.; Edwards,M.J. 1996. The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in c57bl/6 mice Journal of Clinical Investigation, 97 8, 1952

Edwards, M J; Gable, D R; Lentsch, A B; Richardson, J D 1996. The rationale for esophagectomy as the optimal therapy for Barrett's esophagus with high-grade dysplasia. Annals of surgery, 223 5, 585-9; discussion 58

Edwards,M.J.; Gable,D.R.; Lentsch,A.B.; Richardson,J.D. 1996. The rationale for esophagectomy as the optimal therapy for barrett's esophagus with high-grade dysplasia Annals of Surgery, 223 5, 585

Lentsch, A B; Edwards, M J; Miller, F N 1996. Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity. The Journal of laboratory and clinical medicine, 128 1, 75-82

Lentsch, A B; Edwards, M J; Sims, D E; Nakagawa, K; Wellhausen, S R; Miller, F N 1996. Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN mice. Journal of leukocyte biology, 60 1, 51-7

Lentsch,A.B.; Edwards,M.J.; Miller,F.N. 1996. Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity Journal of Laboratory and Clinical Medicine, 128 1, 75

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Nakagawa,K.; Miller,F.N. 1996. Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in mice FASEB Journal, 10 3,

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Nakagawa,K.; Wellhausen,S.R.; Miller,F.N. 1996. Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in c3h/hen mice Journal of Leukocyte Biology, 60 1, 51

Nakagawa, K; Miller, F N; Sims, D E; Lentsch, A B; Miyazaki, M; Edwards, M J 1996. Mechanisms of interleukin-2-induced hepatic toxicity. Cancer research, 56 3, 507-10

Nakagawa,K.; Miller,F.N.; Sims,D.E.; Lentsch,A.B.; Miyazaki,M.; Edwards,M.J. 1996. Mechanisms of interleukin-2-induced hepatic toxicity Cancer Research, 56 3, 507

Lindberg, R A; Slaaf, D W; Lentsch, A B; Miller, F N 1994. Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion. Microvascular research, 47 2, 203-21

Lindberg,R.A.; Slaaf,D.W.; Lentsch,A.B.; Miller,F.N. 1994. Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion Microvascular Research, 47 2, 203

Ziobro R.;Henry B.;Lentsch A.;Edwards M.;Riethmüller J.;Gulbins E. 12-01-2013. Ceramide in cystic fibrosis Clinical Lipidology, 8 6, 681-691

Lentsch A. 12-01-2000. Regulation of acute inflammation by the duffy antigen/ receptor for chemokines (darc): exaggerated r Blood, 96 11 PART I,

Crouch L.;Lentsch A.;Warner R.;Johnson K.;Ward P. 12-01-1997. Regulatory effects of adrenal gland products in IgG immune complex acute lung injury FASEB Journal, 11 3,

Lentsch A.;Shanley T.;Ward P. 12-01-1997. Interleukin-10 protects against IgG immune complex-induced lung injury through suppression of NF-?B FASEB Journal, 11 3,

Lentsch A.;Edwards M.;Sims D.;Nakagawa K.;Miller F. 12-01-1996. Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce t FASEB Journal, 10 3,

Konishi T.;Lentsch A. 10-01-2018. Changes in arachidonic acid metabolism during liver ischemia triggers induction of inflammatory inju Hepatology, 68 4, 1642-1643

Wilson G.;Freeman C.;Nojima H.;Lentsch A. 09-28-2015. CXC chemokine receptor signaling in liver repair and regeneration Signaling Pathways in Liver Diseases: Third Edition, , 166-173

Lentsch A. 07-01-2005. Activation and function of hepatocyte NF-?B in postischemic liver injury Hepatology, 42 1, 216-218

Shin T.;Kuboki S.;Lentsch A. 05-01-2008. Roles of nuclear factor-?B in postischemic liver Hepatology Research, 38 5, 429-440

Konishi T.;Schuster R.;Lentsch A. 04-01-2018. Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and re American Journal of Physiology - Gastrointestinal and Liver Physiology, 314 4, G471-G482

Solan P.;Piraino G.;Hake P.;Denenberg A.;O'Connor M.;Lentsch A.;Zingarelli B. 04-01-2011. Liver X receptor ? activation with the synthetic ligand T0901317 reduces lung injury and inflammatio Shock, 35 4, 367-374

Lentsch A.;Bless N.;Czermak B.;Ward P. 03-20-1998. Determinants of NF-?B activation in acute lung injury FASEB Journal, 12 5,

Konishi T.;Schuster R.M.;Goetzman H.S.;Caldwell C.C.;Lentsch A.B. 03-01-2020. Fibrotic liver has prompt recovery after ischemia-reperfusion injury American journal of physiology. Gastrointestinal and liver physiology, 318 3, G390-G400

Konishi T.;Schuster R.;Lentsch A. 03-01-2019. Liver repair and regeneration after ischemia-reperfusion injury is associated with prolonged fibrosi American Journal of Physiology - Gastrointestinal and Liver Physiology, 316 3, G323-G331

Kim Y.;Abplanalp W.;Jung A.;Schuster R.;Lentsch A.;Gulbins E.;Caldwell C.;Pritts T. 03-01-2018. Endocytosis of red blood cell microparticles by pulmonary endothelial cells is mediated by Rab5 Shock, 49 3, 288-294

Richter J.;Sutton J.;Hexley P.;Johannigman T.;Lentsch A.;Pritts T. 03-01-2018. Leukoreduction of packed red blood cells attenuates proinflammatory properties of storage-derived mi Journal of Surgical Research, 223 , 128-135

Flierl M.;Rittirsch D.;Nadeau B.;Sarma J.;Day D.;Lentsch A.;Huber-Lang M.;Ward P. 02-12-2009. Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response PLoS ONE, 4 2,

Thakar C.V.;Zahedi K.;Revelo M.P.;Wang Z.;Burnham C.E.;Barone S.;Bevans S.;Lentsch A.B.;Rabb H.;Soleimani M. 02-01-2006. Erratum: Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney isc Journal of Clinical Investigation, 116 2, 549

Kim Y.;Goodman M.;Jung A.;Abplanalp W.;Schuster R.;Caldwell C.;Lentsch A.;Pritts T. 01-01-2020. Microparticles from aged packed red blood cell units stimulate pulmonary microthrombus formation via Thrombosis Research, 185 , 160-166

Konishi T.;Schuster R.M.;Goetzman H.S.;Caldwell C.C.;Lentsch A.B. 01-01-2019. Cell-specific regulatory effects of CXCR2 on cholestatic liver injury American Journal of Physiology - Gastrointestinal and Liver Physiology, 317 6, G773-G783

Konishi T.;Lentsch A. 01-01-2017. Hepatic ischemia/reperfusion: Mechanisms of tissue injury, repair, and regeneration Gene Expression, 17 4, 277-287

Freeman C.;Wilson G.;Nojima H.;Lentsch A. 01-01-2015. Role of CXC Chemokines in Liver Repair and Regeneration Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications, , 113-123

Quillin R.;Wilson G.;Nojima H.;Freeman C.;Wang J.;Schuster R.;Blanchard J.;Edwards M.;Gandhi C.;Gulbins E.;Lentsch A. 01-01-2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice Hepatology Research, 45 3, 305-314

Chatterjee T.K.;Basford J.E.;Knoll E.;Tong W.S.;Blanco V.;Blomkalns A.L.;Rudich S.;Lentsch A.B.;Hui D.Y.;Weintraub N.L. 01-01-2014. HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease dur Diabetes, 63 1, 176-187

Sakai N.;Van Sweringen H.;Belizaire R.;Quillin R.;Schuster R.;Blanchard J.;Burns J.;Tevar A.;Edwards M.;Lentsch A. 01-01-2012. Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cell Journal of Gastroenterology and Hepatology (Australia), 27 10, 1609-1616

Lentsch A. 01-01-2003. Proteomics in Practice: A Laboratory Manual of Proteome Analysis Journal of Investigative Surgery, 16 5, 305

Lentsch A.;Ward P. 01-01-1999. Understanding the pathogenesis of inflammation using rodent models: Identification of a transcriptio ILAR Journal, 40 4, 151-156

Lindberg R.;Slaaf D.;Lentsch A.;Miller F. 01-01-1994. Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occ Microvascular Research, 47 2, 203-221

Huber, Nathan L; Bailey, Stephanie R; Schuster, Rebecca; Ogle, Cora K; Lentsch, Alex B; Pritts, Timothy A . Prior thermal injury accelerates endotoxin-induced inflammatory cytokine production and intestinal nuclear factor-?B activation in mice. Journal of burn care & research : official publication of the American Burn Association, 33 2, 279-85

Okaya, Tomohisa; Lentsch, Alex B . Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 16 3, 141-7

Toledo-Pereyra, Luis H; Lopez-Neblina, Fernando; Lentsch, Alex B; Anaya-Prado, Roberto; Romano, Suzanne J; Ward, Peter A . Selectin inhibition modulates NF-kappa B and AP-1 signaling after liver ischemia/reperfusion. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 19 5, 313-22

Ward, Peter A; Lentsch, Alex B . Endogenous regulation of the acute inflammatory response. Molecular and cellular biochemistry, 234-235 1-2, 225-8