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Photo of Chia-I Ko

Chia-I Ko

Adjunct Assistant Professor

Environmental and Public Health Sciences | College of Medicine

  • Bachelor's Degree: Taipei Medical University
  • Master's Degree : University of Lorraine
  • Master's Degree: National Polythechnic Institute of Lorraine
  • Doctoral Degree: University of Lorraine
  • Fellowship: University of Cincinnati
  • Associate Degree: University of Cincinnati
  • Scientist: University of Cincinnati
Contact Information

Peer Reviewed Publications

de Gannes, Matthew; Ko, Chia-I; Zhang, Xiang; Biesiada, Jacek; Niu, Liang; Koch, Sheryl E; Medvedovic, Mario; Rubinstein, Jack; Puga, Alvaro 2020. Dioxin Disrupts Dynamic DNA Methylation Patterns in Genes That Govern Cardiomyocyte Maturation. Toxicological sciences : an official journal of the Society of Toxicology, 178 2, 325-337

Ko, Chia-I; Puga, Alvaro 2017. Does the Aryl Hydrocarbon Receptor Regulate Pluripotency? Current opinion in toxicology, 2 , 1-7

Ko, Chia-I; Fan, Yunxia; de Gannes, Matthew; Wang, Qin; Xia, Ying; Puga, Alvaro 2016. Repression of the Aryl Hydrocarbon Receptor Is Required to Maintain Mitotic Progression and Prevent Loss of Pluripotency of Embryonic Stem Cells. Stem cells (Dayton, Ohio), 34 12, 2825-2839

Wang, Qin; Kurita, Hisaka; Carreira, Vinicius; Ko, Chia-I; Fan, Yunxia; Zhang, Xiang; Biesiada, Jacek; Medvedovic, Mario; Puga, Alvaro 2016. Ah Receptor Activation by Dioxin Disrupts Activin, BMP, and WNT Signals During the Early Differentiation of Mouse Embryonic Stem Cells and Inhibits Cardiomyocyte Functions. Toxicological sciences : an official journal of the Society of Toxicology, 149 2, 346-57

Carreira, Vinicius S; Fan, Yunxia; Kurita, Hisaka; Wang, Qin; Ko, Chia-I; Naticchioni, Mindi; Jiang, Min; Koch, Sheryl; Zhang, Xiang; Biesiada, Jacek; Medvedovic, Mario; Xia, Ying; Rubinstein, Jack; Puga, Alvaro 2015. Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult. PloS one, 10 11, e0142440

Carreira, Vinicius S; Fan, Yunxia; Wang, Qing; Zhang, Xiang; Kurita, Hisaka; Ko, Chia-I; Naticchioni, Mindi; Jiang, Min; Koch, Sheryl; Medvedovic, Mario; Xia, Ying; Rubinstein, Jack; Puga, Alvaro 2015. Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes. Toxicological sciences : an official journal of the Society of Toxicology, 147 2, 425-35

Winans, Bethany; Nagari, Anusha; Chae, Minho; Post, Christina M; Ko, Chia-I; Puga, Alvaro; Kraus, W Lee; Lawrence, B Paige 2015. Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses. Journal of immunology (Baltimore, Md. : 1950), 194 9, 4446-57

Ko, Chia-I; Wang, Qin; Fan, Yunxia; Xia, Ying; Puga, Alvaro 2014. Pluripotency factors and Polycomb Group proteins repress aryl hydrocarbon receptor expression in murine embryonic stem cells. Stem cell research, 12 1, 296-308

Qin Wang, Jing Chen, Chia-I Ko, Yunxia Fan, Vinicius Carreira, Yinglei Chen, Ying Xia, Mario Medvedovic, and Alvaro Puga 2013. Disruption of Aryl Hydrocarbon Receptor Homeostatic Levels during Embryonic Stem Cell Differentiation Alters Expression of Homeobox Transcription Factors that Control Cardiomyogenesis Environmental Health Perspectives, Nov-Dec 2013;121 11-12, 1334

Wang, Jingcai; Chen, Liang; Ko, Chia-I; Zhang, Lin; Puga, Alvaro; Xia, Ying 2012. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation. The Journal of biological chemistry, 287 4, 2787-97

Dumond, Helene; Maufroid, Jean-Pierre; Ko, Chia-I; Chardard, Dominique; Chesnel, Amand; Flament, Stephane 2008. Freemartin in the amphibian Pleurodeles waltl: parabiosis between individuals from opposite sex triggers both germ and somatic cells alterations during female gonad development. Molecular reproduction and development, 75 3, 439-49

Ko, Chia-I; Chesnel, Amand; Mazerbourg, Sabine; Kuntz, Sandra; Flament, St├ęphane; Chardard, Dominique 2008. Female-enriched expression of ERalpha during gonad differentiation of the urodele amphibian Pleurodeles waltl. General and comparative endocrinology, 156 2, 234-45

Wang, Qin; Chen, Jing; Ko, Chia-I; Fan, Yunxia; Carreira, Vinicius; Chen, Yinglei; Xia, Ying; Medvedovic, Mario; Puga, Alvaro . Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis. Environmental health perspectives, 121 11-12, 1334-43