Education/CredentialsPh.D.: Peking UniversityPostDoc training: University of Michigan Contact Information Vontz Center 3316 Office 513-558-4816 Email wang2cr@ucmail.uc.edu Research InterestsMy research interests include selective autophagy, mTORC1 activation, and lipid metabolisms in development and neurogenesis of postnatal neural stem cells; glial micro-environment for cancer metastasis to brain; functions of autophagy in neurodegenerative diseases, e.g. Alzheimer’s disease. Peer Reviewed Publications Nagayach, Aarti; Wang, Chenran 2024. Autophagy in neural stem cells and glia for brain health and diseases. Neural regeneration research, 19 4, 729-736Angst, Gabrielle; Tang, Xin; Wang, Chenran 2023. Functional Analysis of a Novel Immortalized Murine Microglia Cell Line in 3D Spheroid Model. Neurochemical research, 48 9, 2857-2869Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769Tang, Xin; Walter, Ellen; Wohleb, Eric; Fan, Yanbo; Wang, Chenran 2023. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease. Autophagy, , 1-16Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P 2022. MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration. Medicine, 101 40, e30854Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8, Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, , Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Chen, Qixin; Shao, Xintian; Hao, Mingang; Fang, Hongbao; Guan, Ruilin; Tian, Zhiqi; Li, Miaoling; Wang, Chenran; Ji, Liangnian; Chao, Hui; Guan, Jun-Lin; Diao, Jiajie 2020. Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy. Biomaterials, 250 , 120059Deng, Shan; Essandoh, Kobina; Wang, Xiaohong; Li, Yutian; Huang, Wei; Chen, Jing; Peng, Jiangtong; Jiang, Ding-Sheng; Mu, Xingjiang; Wang, Chenran; Peng, Tianqing; Guan, Jun-Lin; Wang, Yigang; Jegga, Anil; Huang, Kai; Fan, Guo-Chang 2020. Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox biology, , 101453Yang, Fuchun; Sun, Shaogang; Wang, Chenran; Haas, Michael; Yeo, Syn; Guan, Jun-Lin 2020. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. British journal of cancer, , Yeo, Syn Kok; Wang, Chenran; Guan, Jun-Lin 2020. Role of FIP200 in inflammatory processes beyond its canonical autophagy function. Biochemical Society transactions, , Wang, Chenran; Haas, Michael A; Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R; Guan, Jun-Lin 2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells. Nature metabolism, 1 11, 1127-1140Chen, Qixin; Jin, Chengzhi; Shao, Xintian; Guan, Ruilin; Tian, Zhiqi; Wang, Chenran; Liu, Fei; Ling, Peixue; Guan, Jun-Lin; Ji, Liangnian; Wang, Fengshan; Chao, Hui; Diao, Jiajie 2018. Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore. Small (Weinheim an der Bergstrasse, Germany), 14 41, e1802166Yeo, Syn Kok; Paul, Ritama; Haas, Michael; Wang, Chenran; Guan, Jun-Lin 2018. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy, 14 7, 1214-1225Wang, Chenran; Yeo, Syn; Haas, Michael A; Guan, Jun-Lin 2017. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. The Journal of cell biology, 216 8, 2581-2596Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin 2016. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes & development, 30 7, 856-69Wang, Chenran; Chen, Song; Yeo, Syn; Karsli-Uzunbas, Gizem; White, Eileen; Mizushima, Noboru; Virgin, Herbert W; Guan, Jun-Lin 2016. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of cell biology, 212 5, 545-60Wen, Jian; Yeo, Syn; Wang, Chenran; Chen, Song; Sun, Shaogang; Haas, Michael A; Tu, Wei; Jin, Feng; Guan, Jun-Lin 2015. Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis. Breast cancer research and treatment, 149 3, 619-29Kim, Edward; Wang, Yuan; Kim, Sun-Jung; Bornhorst, Miriam; Jecrois, Emmanuelle S; Anthony, Todd E; Wang, Chenran; Li, Yi E; Guan, Jun-Lin; Murphy, Geoffrey G; Zhu, Yuan 2014. Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. eLife, 3 , Wei, Huijun; Wang, Chenran; Croce, Carlo M; Guan, Jun-Lin 2014. p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes & development, 28 11, 1204-16Wang, Chenran; Haas, Michael A., Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R.; Guan, Jun-Lin 11-11-2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells Nature Metabolism, 1, , 1127–1140
Research InterestsMy research interests include selective autophagy, mTORC1 activation, and lipid metabolisms in development and neurogenesis of postnatal neural stem cells; glial micro-environment for cancer metastasis to brain; functions of autophagy in neurodegenerative diseases, e.g. Alzheimer’s disease.
Peer Reviewed Publications Nagayach, Aarti; Wang, Chenran 2024. Autophagy in neural stem cells and glia for brain health and diseases. Neural regeneration research, 19 4, 729-736Angst, Gabrielle; Tang, Xin; Wang, Chenran 2023. Functional Analysis of a Novel Immortalized Murine Microglia Cell Line in 3D Spheroid Model. Neurochemical research, 48 9, 2857-2869Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769Tang, Xin; Walter, Ellen; Wohleb, Eric; Fan, Yanbo; Wang, Chenran 2023. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease. Autophagy, , 1-16Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P 2022. MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration. Medicine, 101 40, e30854Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8, Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, , Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Chen, Qixin; Shao, Xintian; Hao, Mingang; Fang, Hongbao; Guan, Ruilin; Tian, Zhiqi; Li, Miaoling; Wang, Chenran; Ji, Liangnian; Chao, Hui; Guan, Jun-Lin; Diao, Jiajie 2020. Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy. Biomaterials, 250 , 120059Deng, Shan; Essandoh, Kobina; Wang, Xiaohong; Li, Yutian; Huang, Wei; Chen, Jing; Peng, Jiangtong; Jiang, Ding-Sheng; Mu, Xingjiang; Wang, Chenran; Peng, Tianqing; Guan, Jun-Lin; Wang, Yigang; Jegga, Anil; Huang, Kai; Fan, Guo-Chang 2020. Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox biology, , 101453Yang, Fuchun; Sun, Shaogang; Wang, Chenran; Haas, Michael; Yeo, Syn; Guan, Jun-Lin 2020. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. British journal of cancer, , Yeo, Syn Kok; Wang, Chenran; Guan, Jun-Lin 2020. Role of FIP200 in inflammatory processes beyond its canonical autophagy function. Biochemical Society transactions, , Wang, Chenran; Haas, Michael A; Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R; Guan, Jun-Lin 2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells. Nature metabolism, 1 11, 1127-1140Chen, Qixin; Jin, Chengzhi; Shao, Xintian; Guan, Ruilin; Tian, Zhiqi; Wang, Chenran; Liu, Fei; Ling, Peixue; Guan, Jun-Lin; Ji, Liangnian; Wang, Fengshan; Chao, Hui; Diao, Jiajie 2018. Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore. Small (Weinheim an der Bergstrasse, Germany), 14 41, e1802166Yeo, Syn Kok; Paul, Ritama; Haas, Michael; Wang, Chenran; Guan, Jun-Lin 2018. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy, 14 7, 1214-1225Wang, Chenran; Yeo, Syn; Haas, Michael A; Guan, Jun-Lin 2017. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. The Journal of cell biology, 216 8, 2581-2596Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin 2016. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes & development, 30 7, 856-69Wang, Chenran; Chen, Song; Yeo, Syn; Karsli-Uzunbas, Gizem; White, Eileen; Mizushima, Noboru; Virgin, Herbert W; Guan, Jun-Lin 2016. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of cell biology, 212 5, 545-60Wen, Jian; Yeo, Syn; Wang, Chenran; Chen, Song; Sun, Shaogang; Haas, Michael A; Tu, Wei; Jin, Feng; Guan, Jun-Lin 2015. Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis. Breast cancer research and treatment, 149 3, 619-29Kim, Edward; Wang, Yuan; Kim, Sun-Jung; Bornhorst, Miriam; Jecrois, Emmanuelle S; Anthony, Todd E; Wang, Chenran; Li, Yi E; Guan, Jun-Lin; Murphy, Geoffrey G; Zhu, Yuan 2014. Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. eLife, 3 , Wei, Huijun; Wang, Chenran; Croce, Carlo M; Guan, Jun-Lin 2014. p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes & development, 28 11, 1204-16Wang, Chenran; Haas, Michael A., Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R.; Guan, Jun-Lin 11-11-2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells Nature Metabolism, 1, , 1127–1140
Nagayach, Aarti; Wang, Chenran 2024. Autophagy in neural stem cells and glia for brain health and diseases. Neural regeneration research, 19 4, 729-736Angst, Gabrielle; Tang, Xin; Wang, Chenran 2023. Functional Analysis of a Novel Immortalized Murine Microglia Cell Line in 3D Spheroid Model. Neurochemical research, 48 9, 2857-2869Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769Tang, Xin; Walter, Ellen; Wohleb, Eric; Fan, Yanbo; Wang, Chenran 2023. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease. Autophagy, , 1-16Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P 2022. MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration. Medicine, 101 40, e30854Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8, Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, , Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14Chen, Qixin; Shao, Xintian; Hao, Mingang; Fang, Hongbao; Guan, Ruilin; Tian, Zhiqi; Li, Miaoling; Wang, Chenran; Ji, Liangnian; Chao, Hui; Guan, Jun-Lin; Diao, Jiajie 2020. Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy. Biomaterials, 250 , 120059Deng, Shan; Essandoh, Kobina; Wang, Xiaohong; Li, Yutian; Huang, Wei; Chen, Jing; Peng, Jiangtong; Jiang, Ding-Sheng; Mu, Xingjiang; Wang, Chenran; Peng, Tianqing; Guan, Jun-Lin; Wang, Yigang; Jegga, Anil; Huang, Kai; Fan, Guo-Chang 2020. Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox biology, , 101453Yang, Fuchun; Sun, Shaogang; Wang, Chenran; Haas, Michael; Yeo, Syn; Guan, Jun-Lin 2020. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. British journal of cancer, , Yeo, Syn Kok; Wang, Chenran; Guan, Jun-Lin 2020. Role of FIP200 in inflammatory processes beyond its canonical autophagy function. Biochemical Society transactions, , Wang, Chenran; Haas, Michael A; Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R; Guan, Jun-Lin 2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells. Nature metabolism, 1 11, 1127-1140Chen, Qixin; Jin, Chengzhi; Shao, Xintian; Guan, Ruilin; Tian, Zhiqi; Wang, Chenran; Liu, Fei; Ling, Peixue; Guan, Jun-Lin; Ji, Liangnian; Wang, Fengshan; Chao, Hui; Diao, Jiajie 2018. Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore. Small (Weinheim an der Bergstrasse, Germany), 14 41, e1802166Yeo, Syn Kok; Paul, Ritama; Haas, Michael; Wang, Chenran; Guan, Jun-Lin 2018. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy, 14 7, 1214-1225Wang, Chenran; Yeo, Syn; Haas, Michael A; Guan, Jun-Lin 2017. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. The Journal of cell biology, 216 8, 2581-2596Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin 2016. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes & development, 30 7, 856-69Wang, Chenran; Chen, Song; Yeo, Syn; Karsli-Uzunbas, Gizem; White, Eileen; Mizushima, Noboru; Virgin, Herbert W; Guan, Jun-Lin 2016. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of cell biology, 212 5, 545-60Wen, Jian; Yeo, Syn; Wang, Chenran; Chen, Song; Sun, Shaogang; Haas, Michael A; Tu, Wei; Jin, Feng; Guan, Jun-Lin 2015. Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis. Breast cancer research and treatment, 149 3, 619-29Kim, Edward; Wang, Yuan; Kim, Sun-Jung; Bornhorst, Miriam; Jecrois, Emmanuelle S; Anthony, Todd E; Wang, Chenran; Li, Yi E; Guan, Jun-Lin; Murphy, Geoffrey G; Zhu, Yuan 2014. Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. eLife, 3 , Wei, Huijun; Wang, Chenran; Croce, Carlo M; Guan, Jun-Lin 2014. p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes & development, 28 11, 1204-16Wang, Chenran; Haas, Michael A., Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R.; Guan, Jun-Lin 11-11-2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells Nature Metabolism, 1, , 1127–1140