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Shouxiong Huang, PhD

  • Doctoral Degree: The Ohio State University. (Veterinary Preventive Medicine, Molecular Microbiology.)
  • Bachelor of Medicine: Beijing University of Traditional Chinese Medicine (Basic Sciences of Traditional Medicine, Immunopharmacology of Natural Products)
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Peer Reviewed Publications

Manju Sharma, Shuangmin Zhang, Liang Niu, David Lewinsohn, Xiang Zhang and Shouxiong Huang* 2020. Mucosal-associated invariant T cells develop an innate-like transcriptomic program in anti-mycobacterial responses Frontiers in Immunology, 11 , 1136. *corresponding author

Shouxiong Huang*, Ming Tan 2020. HLA class I genotypes customize vaccination strategies in immune simulation to combat COVID-19 bioRxiv. , , *corresponding author

Shouxiong Huang*, Quan He, Lin-Fu Zhou* 2020. T cell responses in respiratory viral infections and chronic obstructive pulmonary disease Chinese Medical Journal , 2021; 134(13): 1522-1534. doi: 10.1097/CM9.0000000000001388 , *corresponding author

Kim, Dasom; Chen, Zi; Zhou, Lin-Fu; Huang, Shou-Xiong* 2018. Air pollutants and early origins of respiratory diseases Chronic diseases and translational medicine, 4 2, 75-94

Sharma, Manju; Zhang, Xiang; Huang Shouxiong* 2018. Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking Journal of visual experiment, (*Corresponding author ,

Sharma, Manju; Zhang, Xiang; Zhang, Shuangmin; Niu, Liang; Ho, Shuk-Mei; Chen, Aimin; Huang, Shouxiong* 2017. Inhibition of endocytic lipid antigen presentation by common lipophilic environmental pollutants Scientific reports, 7 1, 2085

Huang, Shouxiong* 2016. Targeting Innate-Like T Cells in Tuberculosis Frontiers in immunology, 7 , 594

Huang, Shouxiong*; Moody, D Branch* 2016. Donor-unrestricted T cells in the human CD1 system Immunogenetics, 68 8, 577-96 *corresponding authors

Van Rhijn, Ildiko; van Berlo, Twan; Hilmenyuk, Tamara; Cheng, Tan-Yun; Wolf, Benjamin J; Tatituri, Raju V V; Uldrich, Adam P; Napolitani, Giorgio; Cerundolo, Vincenzo; Altman, John D; Willemsen, Peter; Huang, Shouxiong; Rossjohn, Jamie; Besra, Gurdyal S; Brenner, Michael B; Godfrey, Dale I; Moody, D Branch 2016. Human autoreactive T cells recognize CD1b and phospholipids. Proceedings of the National Academy of Sciences of the United States of America, 113 2, 380-5

de Jong, Annemieke; Cheng, Tan-Yun; Huang, Shouxiong; Gras, Stephanie; Birkinshaw, Richard W; Kasmar, Anne G; Van Rhijn, Ildiko; Peña-Cruz, Victor; Ruan, Daniel T; Altman, John D; Rossjohn, Jamie; Moody, D Branch 2014. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens Nature immunology, 15 2, 177-85

Ly, Dalam; Kasmar, Anne G; Cheng, Tan-Yun; de Jong, Annemieke; Huang, Shouxiong; Roy, Sobhan; Bhatt, Apoorva; van Summeren, Ruben P; Altman, John D; Jacobs, William R; Adams, Erin J; Minnaard, Adriaan J; Porcelli, Steven A; Moody, D Branch 2013. CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens The Journal of experimental medicine, 210 4, 729-41

Young, Mary H; U 2013. MAIT cell recognition of MR1 on bacterially infected and uninfected cells PloS one, 8 1, e53789

Chua, Wei-Jen; Kim, Sojung; Myers, Nancy; Huang, Shouxiong; Yu, Lawrence; Fremont, Daved H; Diamond, Michael S; Hansen, Ted H 2011. Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells Journal of immunology, 186 8, 4744-50

Huang, Shouxiong; Cheng, Tan-Yun; Young, David C; Layre, Emilie; Madigan, Cressida A; Shires, John; Cerundolo, Vincenzo; Altman, John D; Moody, D Branch 2011. Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system Proceedings of the National Academy of Sciences of the United States of America, 108 48, 19335-40

Le Bourhis, Lionel; Martin, Emmanuel; Péguillet, Isabelle; Guihot, Amélie; Froux, Nathalie; Coré, Maxime; Lévy, Eva; Dusseaux, Mathilde; Meyssonnier, Vanina; Premel, Virginie; Ngo, Charlotte; Riteau, Béatrice; Duban, Livine; Robert, Delphine; Huang, Shouxiong; Rottman, Martin; Soudais, Claire; Lantz, Olivier 2010. Antimicrobial activity of mucosal-associated invariant T cells Nature immunology, 11 8, 701-8

Huang, Shouxiong; Martin, Emmanuel; Kim, Sojung; Yu, Lawrence; Soudais, Claire; Fremont, Daved H; Lantz, Olivier; Hansen, Ted H 2009. MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution Proceedings of the National Academy of Sciences of the United States of America, 106 20, 8290-5

Huang, Shouxiong; Gilfillan, Susan; Kim, Sojung; Thompson, Bruce; Wang, Xiaoli; Sant, Andrea J; Fremont, Daved H; Lantz, Olivier; Hansen, Ted H 2008. MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells The Journal of experimental medicine, 205 5, 1201-11

Hansen, Ted H; Huang, Shouxiong; Arnold, Phoebe L; Fremont, Daved H 2007. Patterns of nonclassical MHC antigen presentation Nature immunology, 8 6, 563-8

Huang, Shouxiong; Sahin, Orhan; Zhang, Qijing 2007. Infection-induced antibodies against the major outer membrane protein of Campylobacter jejuni mainly recognize conformational epitopes FEMS microbiology letters, 272 2, 137-43

Huang, Shouxiong; Gilfillan, Susan; Cella, Marina; Miley, Michael J; Lantz, Olivier; Lybarger, Lonnie; Fremont, Daved H; Hansen, Ted H 2005. Evidence for MR1 antigen presentation to mucosal-associated invariant T cells The Journal of biological chemistry, 280 22, 21183-93

Huang, Shouxiong; Luangtongkum, Taradon; Morishita, Teresa Y; Zhang, Qijing 2005. Molecular typing of Campylobacter strains using the cmp gene encoding the major outer membrane protein Foodborne pathogens and disease, 2 1, 12-23

Luo, Naidan; Pereira, Sonia; Sahin, Orhan; Lin, Jun; Huang, Shouxiong; Michel, Linda; Zhang, Qijing 2005. Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure Proceedings of the National Academy of Sciences of the United States of America, 102 3, 541-6

Sahin, Orhan; Luo, Naidan; Huang, Shouxiong; Zhang, Qijing 2003. Effect of Campylobacter-specific maternal antibodies on Campylobacter jejuni colonization in young chickens Applied and environmental microbiology, 69 9, 5372-9

Lin, Jun; Huang, Shouxiong; Zhang, Qijing 2002. Outer membrane proteins: key players for bacterial adaptation in host niches Microbes and infection / Institut Pasteur, 4 3, 325-31

Zhang, Q; Meitzler, J C; Huang, S; Morishita, T 2000. Sequence polymorphism, predicted secondary structures, and surface-exposed conformational epitopes of Campylobacter major outer membrane protein Infection and immunity, 68 10, 5679-89