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Photo of Xuefeng Wang

Xuefeng Wang

Associate Professor

Hoxworth Blood Center | College of Medicine

Contact Information

Peer Reviewed Publications

S. Kundu, K. Pal, A. Pyne and X. Wang 2025. Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles Nature Communications, ,

V. Pandey, S. Kundu, A. Pyne and X. Wang 2025. Live-Cell Imaging of Single Integrin Tensions with Minimal Background Fluorescence Noise Biophysical Journal, ,

Tu Y.; Wang X. 12-02-2020. Recent advances in cell adhesive force microscopy Sensors (Switzerland), 20 24, 1-14

Tu Y.; Wang X. 12-01-2021. Tracking cell migration by cellular force footprint recorded with a mechano-optical biosensor Biosensors and Bioelectronics, 193 ,

Wang X.; Sun J.; Xu Q.; Chowdhury F.; Roein-Peikar M.; Wang Y.; Ha T. 12-01-2015. Integrin Molecular Tension within Motile Focal Adhesions Biophysical Journal, 109 11, 2259-2267

Zhao Y.; Wang Y.; Sarkar A.; Wang X. 11-30-2018. Keratocytes Generate High Integrin Tension at the Trailing Edge to Mediate Rear De-adhesion during R iScience, 9 , 502-512

Wang Y.; Wang X. 11-15-2016. Integrins outside focal adhesions transmit tensions during stable cell adhesion Scientific Reports, 6 ,

Sarkar A.; Niraula G.; LeVine D.; Zhao Y.; Tu Y.; Mollaeian K.; Ren J.; Que L.; Wang X. 10-27-2023. Development of a Ratiometric Tension Sensor Exclusively Responding to Integrin Tension Magnitude in ACS Sensors, 8 10, 3701-3712

Tu Y.; Pal K.; Austin J.; Wang X. 10-24-2022. Filopodial adhesive force in discrete nodes revealed by integrin molecular tension imaging Current Biology, 32 20, 4386-4396.e3

Sarkar A.; LeVine D.N.; Kuzmina N.; Zhao Y.; Wang X. 10-19-2020. Cell Migration Driven by Self-Generated Integrin Ligand Gradient on Ligand-Labile Surfaces Current Biology, 30 20, 4022-4032.e5

Chowdhury F.; Li I.T.S.; Leslie B.J.; Do?anay S.; Singh R.; Wang X.; Seong J.; Lee S.H.; Park S.; Wang N.; Ha T. 10-01-2015. Single molecular force across single integrins dictates cell spreading Integrative Biology (United Kingdom), 7 10, 1265-1271

Rahil Z.; Pedron S.; Wang X.; Ha T.; Harley B.; Leckband D. 09-01-2016. Nanoscale mechanics guides cellular decision making Integrative Biology (United Kingdom), 8 9, 929-935

Mao S.; Sarkar A.; Wang Y.; Song C.; LeVine D.; Wang X.; Que L. 08-21-2021. Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear Lab on a Chip, 21 16, 3128-3136

Niraula G.; Pyne A.; Wang X. 07-26-2024. Develop Tandem Tension Sensor to Gauge Integrin-Transmitted Molecular Forces ACS Sensors, 9 7, 3660-3670

Wang X.; Park S.; Zeng L.; Jain A.; Ha T. 07-17-2018. Toward Single-Cell Single-Molecule Pull-Down Biophysical Journal, 115 2, 283-288

Sarkar A.; Zhao Y.; Wang Y.; Wang X. 06-25-2018. Force-activatable coating enables high-resolution cellular force imaging directly on regular cell cu Physical Biology, 15 6,

Chowdhury F.; Li I.T.S.; Ngo T.T.M.; Leslie B.J.; Kim B.C.; Sokoloski J.E.; Weiland E.; Wang X.; Chemla Y.R.; Lohman T.M.; Ha T. 06-08-2016. Defining single molecular forces required for notch activation using nano yoyo Nano Letters, 16 6, 3892-3897

Wang Y.; Zhao Y.; Sarkar A.; Wang X. 05-01-2019. Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane Journal of Biophotonics, 12 5,

Zhao Y.; Pal K.; Tu Y.; Wang X. 04-15-2020. Cellular Force Nanoscopy with 50 nm Resolution Based on Integrin Molecular Tension Imaging and Local Journal of the American Chemical Society, 142 15, 6930-6934

Zhao Y.; Wetter N.M.; Wang X. 04-01-2019. Imaging integrin tension and cellular force at submicron resolution with an integrative tension sens Journal of Visualized Experiments, 2019 146,

Pal K.; Tu Y.; Wang X. 02-22-2022. Single-Molecule Force Imaging Reveals That Podosome Formation Requires No Extracellular Integrin-Lig ACS Nano, 16 2, 2481-2493

Zhao Y.; Sarkar A.; Wang X. 02-15-2020. Peptide nucleic acid based tension sensor for cellular force imaging with strong DNase resistance Biosensors and Bioelectronics, 150 ,

Wang Y.; LeVine D.N.; Gannon M.; Zhao Y.; Sarkar A.; Hoch B.; Wang X. 02-15-2018. Force-activatable biosensor enables single platelet force mapping directly by fluorescence imaging Biosensors and Bioelectronics, 100 , 192-200

Wang X.; Rahil Z.; Li I.T.S.; Chowdhury F.; Leckband D.E.; Chemla Y.R.; Ha T. 02-15-2016. Constructing modular and universal single molecule tension sensor using protein G to study mechano-s Scientific Reports, 6 ,

Austin J.; Tu Y.; Pal K.; Wang X. 01-03-2023. Vinculin transmits high-level integrin tensions that are dispensable for focal adhesion formation Biophysical Journal, 122 1, 156-167

Tu Y.; Wang X. 01-01-2023. Imaging Cell Adhesive Force at the Single Molecule Level Methods in Molecular Biology, 2600 , 207-217

Pal K.; Zhao Y.; Wang Y.; Wang X. 01-01-2021. Ubiquitous membrane-bound DNase activity in podosomes and invadopodia Journal of Cell Biology, 220 7,

Lee M.K.; Park J.; Wang X.; Roein-Peikar M.; Ko E.; Qin E.; Lee J.; Ha T.; Kong H. 01-01-2016. Rupture force of cell adhesion ligand tethers modulates biological activities of a cell-laden hydrog Chemical Communications, 52 26, 4757-4760

Roein-Peikar M.; Xu Q.; Wang X.; Ha T. 01-01-2016. Ultrasensitivity of cell adhesion to the presence of mechanically strong ligands Physical Review X, 6 1,

Wang X.; Ha T. 01-01-2013. Defining single molecular forces required to activate integrin and Notch signaling Science, 340 6135, 991-994