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Lesley Arnold, MD

Professor

Director of the Women’s Health Research Program

Psychiatry & Behavioral Neuroscience | College of Medicine

Education/Credentials
  • Bachelor's Degree: Cornell University
  • Medical Degree: University of Cincinnati College of Medicine
  • Residency: University of Cincinnati College of Medicine
Board Certifications & Licenses

American Board of Psychiatry and Neurology (Psychiatry) (Certification Date: 19920130)

Specialties

Psychiatry

Contact Information
Research Interests

Research interests include Fibromyalgia, Chronic Pain, Women’s Health, and Mood and Anxiety Disorders.

Clinical Interests

Psychiatry

Peer Reviewed Publications

Ailani, Jessica; Lipton, Richard B; Goadsby, Peter J; Guo, Hua; Miceli, Rosa; Severt, Lawrence; Finnegan, Michelle; Trugman, Joel M 2021. Atogepant for the Preventive Treatment of Migraine. The New England journal of medicine, 385 8, 695-706

Kleykamp, Bethea A; Ferguson, McKenzie C; McNicol, Ewan; Bixho, Ida; Arnold, Lesley M; Edwards, Robert R; Fillingim, Roger; Grol-Prokopczyk, Hanna; Turk, Dennis C; Dworkin, Robert H 2021. The Prevalence of Psychiatric and Chronic Pain Comorbidities in Fibromyalgia: an ACTTION systematic review. Seminars in arthritis and rheumatism, 51 1, 166-174

Arnold, Lesley M; Bennett, Robert M; Crofford, Leslie J; Dean, Linda E; Clauw, Daniel J; Goldenberg, Don L; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Sarzi-Puttini, Piercarlo; Buskila, Dan; Macfarlane, Gary J 2019. Response to Wolfe. Letter to the Editor, "Fibromyalgia Criteria". The journal of pain, 20 6, 741-742

Arnold, Lesley M; Bennett, Robert M; Crofford, Leslie J; Dean, Linda E; Clauw, Daniel J; Goldenberg, Don L; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Sarzi-Puttini, Piercarlo; Buskila, Dan; Macfarlane, Gary J 2019. AAPT Diagnostic Criteria for Fibromyalgia. The journal of pain, 20 6, 611-628

Arnold, Lesley M; Whitaker, Susan; Hsu, Ching; Jacobs, David; Merante, Domenico 2019. Efficacy and safety of mirogabalin for the treatment of fibromyalgia: results from three 13-week randomized, double-blind, placebo- and active-controlled, parallel-group studies and a 52-week open-label extension study. Current medical research and opinion, 35 10, 1825-1835

Kashikar-Zuck, Susmita; Cunningham, Natoshia; Peugh, James; Black, William R; Nelson, Sarah; Lynch-Jordan, Anne M; Pfeiffer, Megan; Tran, Susan T; Ting, Tracy V; Arnold, Lesley M; Carle, Adam; Noll, Jennie; Powers, Scott W; Lovell, Daniel J 2019. Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time. Pain, 160 2, 433-441

Upadhyaya, Himanshu P; Arnold, Lesley M; Alaka, Karla; Qiao, Meihua; Williams, David; Mehta, Renata 2019. Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial. Pediatric rheumatology online journal, 17 1, 27

Arnold, Lesley M; Choy, Ernest; Clauw, Daniel J; Oka, Hiroshi; Whalen, Ed; Semel, David; Pauer, Lynne; Knapp, Lloyd 2018. An evidence-based review of pregabalin for the treatment of fibromyalgia. Current medical research and opinion, 34 8, 1397-1409

Arnold, Lesley M; Arsenault, Pierre; Huffman, Cynthia; Patrick, Jeffrey; Messig, Michael; Chew, Marci; Sanin, Luis; Scavone, Joseph; Pauer, Lynne; Clair, Andrew 2017. Corrections to: Once-daily controlled-release pregabalin in the treatment of patients with fibromyalgia: a phase III, double-blind, randomized withdrawal, placebo-controlled study. Current medical research and opinion, 33 4, 795-796

Arnold, Lesley M; Clauw, Daniel J 2017. Challenges of implementing fibromyalgia treatment guidelines in current clinical practice. Postgraduate medicine, 129 7, 709-714

Arnold, Lesley M; McCarberg, Bill H; Clair, Andrew G; Whalen, Ed; Thomas, Neal; Jorga, Anamaria; Pauer, Lynne; Vissing, Richard; Park, Peter W 2017. Dose-response of pregabalin for diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia. Postgraduate medicine, 129 8, 921-933

Dean, Linda E; Arnold, Lesley; Crofford, Leslie; Bennett, Robert; Goldenberg, Don; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Clauw, Dan; Sarzi-Puttini, Piercarlo; Jones, Gareth T; Ayorinde, Abimbola; Flüß, Elisa; Beasley, Marcus; Macfarlane, Gary J 2017. Impact of Moving From a Widespread to Multisite Pain Definition on Other Fibromyalgia Symptoms. Arthritis care & research, 69 12, 1878-1886

Arnold, Lesley M; Choy, Ernest; Clauw, Daniel J; Goldenberg, Don L; Harris, Richard E; Helfenstein, Milton; Jensen, Troels Staehelin; Noguchi, Koichi; Silverman, Stuart L; Ushida, Takahiro; Wang, Guochun 2016. Fibromyalgia and Chronic Pain Syndromes: A White Paper Detailing Current Challenges in the Field. The Clinical journal of pain, 32 9, 737-46

Arnold, Lesley M; Schikler, Kenneth N; Bateman, Lucinda; Khan, Tahira; Pauer, Lynne; Bhadra-Brown, Pritha; Clair, Andrew; Chew, Marci L; Scavone, Joseph 2016. Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study. Pediatric rheumatology online journal, 14 1, 46

Kashikar-Zuck, Susmita; King, Christopher; Ting, Tracy V; Arnold, Lesley M 2016. Juvenile Fibromyalgia: Different from the Adult Chronic Pain Syndrome? Current rheumatology reports, 18 4, 19

Arnold, Lesley M; Bateman, Lucinda; Palmer, Robert H; Lin, Yuhua 2015. Preliminary experience using milnacipran in patients with juvenile fibromyalgia: lessons from a clinical trial program. Pediatric rheumatology online journal, 13 , 27

Arnold, Lesley M; Emir, Birol; Pauer, Lynne; Resnick, Malca; Clair, Andrew 2015. Time to improvement of pain and sleep quality in clinical trials of pregabalin for the treatment of fibromyalgia. Pain medicine (Malden, Mass.), 16 1, 176-85

Arnold, Lesley M; Sarzi-Puttini, Piercarlo; Arsenault, Pierre; Khan, Tahira; Bhadra Brown, Pritha; Clair, Andrew; Scavone, Joseph M; Driscoll, Joseph; Landen, Jaren; Pauer, Lynne 2015. Efficacy and Safety of Pregabalin in Patients with Fibromyalgia and Comorbid Depression Taking Concurrent Antidepressant Medication: A Randomized, Placebo-controlled Study. The Journal of rheumatology, 42 7, 1237-44

Cunningham, Natoshia Raishevich; Tran, Susan T; Lynch-Jordan, Anne M; Ting, Tracy V; Sil, Soumitri; Strotman, Daniel; Noll, Jennie G; Powers, Scott W; Arnold, Lesley M; Kashikar-Zuck, Susmita 2015. Psychiatric Disorders in Young Adults Diagnosed with Juvenile Fibromyalgia in Adolescence. The Journal of rheumatology, 42 12, 2427-33

Arnold, Lesley M; Arsenault, Pierre; Huffman, Cynthia; Patrick, Jeffrey L; Messig, Michael; Chew, Marci L; Sanin, Luis; Scavone, Joseph M; Pauer, Lynne; Clair, Andrew G 2014. Once daily controlled-release pregabalin in the treatment of patients with fibromyalgia: a phase III, double-blind, randomized withdrawal, placebo-controlled study. Current medical research and opinion, 30 10, 2069-83

Fillingim, Roger B; Bruehl, Stephen; Dworkin, Robert H; Dworkin, Samuel F; Loeser, John D; Turk, Dennis C; Widerstrom-Noga, Eva; Arnold, Lesley; Bennett, Robert; Edwards, Robert R; Freeman, Roy; Gewandter, Jennifer; Hertz, Sharon; Hochberg, Marc; Krane, Elliot; Mantyh, Patrick W; Markman, John; Neogi, Tuhina; Ohrbach, Richard; Paice, Judith A; Porreca, Frank; Rappaport, Bob A; Smith, Shannon M; Smith, Thomas J; Sullivan, Mark D; Verne, G Nicholas; Wasan, Ajay D; Wesselmann, Ursula 2014. The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions. The journal of pain, 15 3, 241-9

Kashikar-Zuck, Susmita; Cunningham, Natoshia; Sil, Soumitri; Bromberg, Maggie H; Lynch-Jordan, Anne M; Strotman, Daniel; Peugh, James; Noll, Jennie; Ting, Tracy V; Powers, Scott W; Lovell, Daniel J; Arnold, Lesley M 2014. Long-term outcomes of adolescents with juvenile-onset fibromyalgia in early adulthood. Pediatrics, 133 3, e592-600

Kleinman, Leah; Mannix, Sally; Arnold, Lesley M; Burbridge, Claire; Howard, Kellee; McQuarrie, Kelly; Pitman, Verne; Resnick, Malca; Roth, Tom; Symonds, Tara 2014. Assessment of sleep in patients with fibromyalgia: qualitative development of the fibromyalgia sleep diary. Health and quality of life outcomes, 12 , 111

Martin, Susan A; Coon, Cheryl D; McLeod, Lori D; Chandran, Arthi; Arnold, Lesley M 2014. Evaluation of the fibromyalgia diagnostic screen in clinical practice. Journal of evaluation in clinical practice, 20 2, 158-65

Roth, Thomas; Arnold, Lesley M; Garcia-Borreguero, Diego; Resnick, Malca; Clair, Andrew G 2014. A review of the effects of pregabalin on sleep disturbance across multiple clinical conditions. Sleep medicine reviews, 18 3, 261-71

Sil, Soumitri; Arnold, Lesley M; Lynch-Jordan, Anne; Ting, Tracy V; Peugh, James; Cunningham, Natoshia; Powers, Scott W; Lovell, Daniel J; Hashkes, Philip J; Passo, Murray; Schikler, Kenneth N; Kashikar-Zuck, Susmita 2014. Identifying treatment responders and predictors of improvement after cognitive-behavioral therapy for juvenile fibromyalgia. Pain, 155 7, 1206-1212

Arnold, Lesley M; Cappelleri, Joseph C; Clair, Andrew; Masters, Elizabeth T 2013. Interpreting effect sizes and clinical relevance of pharmacological interventions for fibromyalgia. Pain and therapy, 2 1, 65-71

Arnold, Lesley M; Fan, Jinbo; Russell, I Jon; Yunus, Muhammad B; Khan, Muhammad Asim; Kushner, Irving; Olson, Jane M; Iyengar, Sudha K 2013. The fibromyalgia family study: a genome-wide linkage scan study. Arthritis and rheumatism, 65 4, 1122-8

Arnold, Lesley M; Palmer, Robert H; Ma, Yimin 2013. A 3-year, open-label, flexible-dosing study of milnacipran for the treatment of fibromyalgia. The Clinical journal of pain, 29 12, 1021-8

Joffe, Naomi E; Lynch-Jordan, Anne; Ting, Tracy V; Arnold, Lesley M; Hashkes, Philip J; Lovell, Daniel J; Passo, Murray H; Powers, Scott W; Schikler, Kenneth N; Kashikar-Zuck, Susmita 2013. Utility of the PedsQL rheumatology module as an outcome measure in juvenile fibromyalgia. Arthritis care & research, 65 11, 1820-7

Kashikar-Zuck, Susmita; Sil, Soumitri; Lynch-Jordan, Anne M; Ting, Tracy V; Peugh, James; Schikler, Kenneth N; Hashkes, Philip J; Arnold, Lesley M; Passo, Murray; Richards-Mauze, Margaret M; Powers, Scott W; Lovell, Daniel J 2013. Changes in pain coping, catastrophizing, and coping efficacy after cognitive-behavioral therapy in children and adolescents with juvenile fibromyalgia. The journal of pain, 14 5, 492-501

Wells, Alvin F; Arnold, Lesley M; Curtis, Cassandra E; Dunegan, L Jean; Lapp, Charles W; McCarberg, Bill H; Clair, Andrew 2013. Integrating health information technology and electronic health records into the management of fibromyalgia. Postgraduate medicine, 125 4, 70-7

Arnold, Lesley M; Clauw, Daniel J; Dunegan, L Jean; Turk, Dennis C 2012. A framework for fibromyalgia management for primary care providers. Mayo Clinic proceedings, 87 5, 488-96

Arnold, Lesley M; Emir, Birol; Murphy, T Kevin; Zeiher, Bernhardt G; Pauer, Lynne; Scott, Gayle; Petersel, Danielle 2012. Safety profile and tolerability of up to 1 year of pregabalin treatment in 3 open-label extension studies in patients with fibromyalgia. Clinical therapeutics, 34 5, 1092-102

Arnold, Lesley M; Hirsch, Ian; Sanders, Paul; Ellis, Amanda; Hughes, Bernadette 2012. Safety and efficacy of esreboxetine in patients with fibromyalgia: a fourteen-week, randomized, double-blind, placebo-controlled, multicenter clinical trial. Arthritis and rheumatism, 64 7, 2387-97

Arnold, Lesley M; Palmer, Robert H; Hufford, Michael R; Chen, Wei 2012. Effect of milnacipran on body weight in patients with fibromyalgia. International journal of general medicine, 5 , 879-87

Arnold, Lesley M; Stanford, Sharon B; Welge, Jeffrey A; Crofford, Leslie J 2012. Development and testing of the fibromyalgia diagnostic screen for primary care. Journal of women's health (2002), 21 2, 231-9

Arnold, Lesley M; Williams, David A; Hudson, James I; Martin, Susan A; Clauw, Daniel J; Crofford, Leslie J; Wang, Fujun; Emir, Birol; Lai, Chinglin; Zablocki, Rong; Mease, Philip J 2012. Development of responder definitions for fibromyalgia clinical trials. Arthritis and rheumatism, 64 3, 885-94

Gara, Michael A; Vega, William A; Arndt, Stephan; Escamilla, Michael; Fleck, David E; Lawson, William B; Lesser, Ira; Neighbors, Harold W; Wilson, Daniel R; Arnold, Lesley M; Strakowski, Stephen M 2012. Influence of patient race and ethnicity on clinical assessment in patients with affective disorders. Archives of general psychiatry, 69 6, 593-600

Kashikar-Zuck, Susmita; Ting, Tracy V; Arnold, Lesley M; Bean, Judy; Powers, Scott W; Graham, T Brent; Passo, Murray H; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Lynch-Jordan, Anne M; Banez, Gerard; Richards, Margaret M; Lovell, Daniel J 2012. Cognitive behavioral therapy for the treatment of juvenile fibromyalgia: a multisite, single-blind, randomized, controlled clinical trial. Arthritis and rheumatism, 64 1, 297-305

Mariutto, Elizabeth N; Stanford, Sharon B; Kashikar-Zuck, Susmita; Welge, Jeffrey A; Arnold, Lesley M 2012. An exploratory, open trial of fluoxetine treatment of juvenile fibromyalgia. Journal of clinical psychopharmacology, 32 2, 293-5

Saxe, Philippe A; Arnold, Lesley M; Palmer, Robert H; Gendreau, R Michael; Chen, Wei 2012. Short-term (2-week) effects of discontinuing milnacipran in patients with fibromyalgia. Current medical research and opinion, 28 5, 815-21

Arnold, Lesley M; Clauw, Daniel J; McCarberg, Bill H 2011. Improving the recognition and diagnosis of fibromyalgia. Mayo Clinic proceedings, 86 5, 457-64

Arnold, Lesley M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M 2011. Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial. Arthritis research & therapy, 13 3, R86

Arnold, Lesley M; Zlateva, Gergana; Sadosky, Alesia; Emir, Birol; Whalen, Ed 2011. Correlations between fibromyalgia symptom and function domains and patient global impression of change: a pooled analysis of three randomized, placebo-controlled trials of pregabalin. Pain medicine (Malden, Mass.), 12 2, 260-7

Clauw, Daniel J; Arnold, Lesley M; McCarberg, Bill H 2011. The science of fibromyalgia. Mayo Clinic proceedings, 86 9, 907-11

Mease, Philip J; Clauw, Daniel J; Christensen, Robin; Crofford, Leslie J; Gendreau, R Michael; Martin, Susan A; Simon, Lee S; Strand, Vibeke; Williams, David A; Arnold, Lesley M 2011. Toward development of a fibromyalgia responder index and disease activity score: OMERACT module update. The Journal of rheumatology, 38 7, 1487-95

Mease, Philip J; Spaeth, Michael; Clauw, Daniel J; Arnold, Lesley M; Bradley, Laurence A; Russell, I Jon; Kajdasz, Daniel K; Walker, Daniel J; Chappell, Amy S 2011. Estimation of minimum clinically important difference for pain in fibromyalgia. Arthritis care & research, 63 6, 821-6

Wang, Fujun; Ruberg, Stephen J; Gaynor, Paula J; Heinloth, Alexandra N; Arnold, Lesley M 2011. Early improvement in pain predicts pain response at endpoint in patients with fibromyalgia. The journal of pain, 12 10, 1088-94

Williams, David A; Arnold, Lesley M 2011. Measures of fibromyalgia: Fibromyalgia Impact Questionnaire (FIQ), Brief Pain Inventory (BPI), Multidimensional Fatigue Inventory (MFI-20), Medical Outcomes Study (MOS) Sleep Scale, and Multiple Ability Self-Report Questionnaire (MASQ). Arthritis care & research, 63 Suppl 11 , S86-97

Arnold, Lesley M 2010. The pathophysiology, diagnosis and treatment of fibromyalgia. The Psychiatric clinics of North America, 33 2, 375-408

Arnold, Lesley M; Chatamra, Krai; Hirsch, Ian; Stoker, Malcolm 2010. Safety and efficacy of esreboxetine in patients with fibromyalgia: An 8-week, multicenter, randomized, double-blind, placebo-controlled study. Clinical therapeutics, 32 9, 1618-32

Arnold, Lesley M; Clauw, Daniel J 2010. Fibromyalgia syndrome: practical strategies for improving diagnosis and patient outcomes. The American journal of medicine, 123 6, S2

Arnold, Lesley M; Clauw, Daniel; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M 2010. Flexible Dosed Duloxetine in the Treatment of Fibromyalgia: A Randomized, Double-blind, Placebo-controlled Trial. The Journal of rheumatology, ,

Arnold, Lesley M; Gendreau, R Michael; Palmer, Robert H; Gendreau, Judy F; Wang, Yong 2010. Efficacy and safety of milnacipran 100 mg/day in patients with fibromyalgia: Results of a randomized, double-blind, placebo-controlled trial. Arthritis and rheumatism, ,

Arnold, Lesley; Mease, Philip; Silverman, Stuart 2010. Pregabalin: an alpha2-delta (alpha2-delta) ligand for the management of fibromyalgia. The American journal of managed care, 16 5 Suppl, S138-43

Kashikar-Zuck, Susmita; Flowers, Stacy R; Verkamp, Emily; Ting, Tracy V; Lynch-Jordan, Anne M; Graham, T Brent; Passo, Murray; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Banez, Gerard; Richards, Margaret M; Powers, Scott W; Arnold, Lesley M; Lovell, Daniel 2010. Actigraphy-based physical activity monitoring in adolescents with juvenile primary fibromyalgia syndrome. The journal of pain : official journal of the American Pain Society, 11 9, 885-93

Kashikar-Zuck, Susmita; Johnston, Megan; Ting, Tracy V; Graham, Brent T; Lynch-Jordan, Anne M; Verkamp, Emily; Passo, Murray; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Banez, Gerard; Richards, Margaret M; Powers, Scott W; Arnold, Lesley M; Lovell, Daniel 2010. Relationship between School Absenteeism and Depressive Symptoms among Adolescents with Juvenile Fibromyalgia. Journal of pediatric psychology, 35 9, 996-1004

Arnold, Lesley M 2009. Strategies for managing fibromyalgia. The American journal of medicine, 122 12 Suppl, S31-43

Arnold, Lesley M 2009. Advances in the management of fibromyalgia. CNS spectrums, 14 10 Suppl 8, 12-6; discussion 17-

Arnold, Lesley M 2009. Pain and the brain: chronic widespread pain. The Journal of clinical psychiatry, 70 4, e10

Arnold, Lesley M; Clauw, Daniel J; Wohlreich, Madelaine M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Chappell, Amy S 2009. Efficacy of duloxetine in patients with fibromyalgia: pooled analysis of 4 placebo-controlled clinical trials. Primary care companion to the Journal of clinical psychiatry, 11 5, 237-44

Choy, Ernest H; Arnold, Lesley M; Clauw, Daniel J; Crofford, Leslie J; Glass, Jennifer M; Simon, Lee S; Martin, Susan A; Strand, C Vibeke; Williams, David A; Mease, Philip J 2009. Content and criterion validity of the preliminary core dataset for clinical trials in fibromyalgia syndrome. The Journal of rheumatology, 36 10, 2330-4

Hudson, James I; Arnold, Lesley M; Bradley, Laurence A; Choy, Ernest H S; Mease, Philip J; Wang, Fujun; Ahl, Jonna; Wohlreich, Madelaine M 2009. What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine. The Journal of rheumatology, 36 11, 2517-22

Mease, Philip; Arnold, Lesley M; Choy, Ernest H; Clauw, Daniel J; Crofford, Leslie J; Glass, Jennifer M; Martin, Susan A; Morea, Jessica; Simon, Lee; Strand, C Vibeke; Williams, David A 2009. Fibromyalgia syndrome module at OMERACT 9: domain construct. The Journal of rheumatology, 36 10, 2318-29

Arnold, Lesley M 2008. Management of fibromyalgia and comorbid psychiatric disorders. The Journal of clinical psychiatry, 69 Suppl 2 , 14-9

Arnold, Lesley M; Bradley, Laurence A; Clauw, Daniel J; Glass, Jennifer M; Goldenberg, Don L 2008. Multidisciplinary care and stepwise treatment for fibromyalgia. The Journal of clinical psychiatry, 69 12, e35

Arnold, Lesley M; Bradley, Laurence A; Clauw, Daniel J; Glass, Jennifer M; Goldenberg, Don L 2008. Evaluating and diagnosing fibromyalgia and comorbid psychiatric disorders. The Journal of clinical psychiatry, 69 10, e28

Arnold, Lesley M; Crofford, Leslie J; Mease, Philip J; Burgess, Somali Misra; Palmer, Susan C; Abetz, Linda; Martin, Susan A 2008. Patient perspectives on the impact of fibromyalgia. Patient education and counseling, 73 1, 114-20

Arnold, Lesley M; Jain, Rakesh; Glazer, William M 2008. Pain and the brain. The Journal of clinical psychiatry, 69 9, e25

Arnold, Lesley M; Russell, I Jon; Diri, E W; Duan, W Rachel; Young, James P; Sharma, Uma; Martin, Susan A; Barrett, Jeannette A; Haig, George 2008. A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia. The journal of pain : official journal of the American Pain Society, 9 9, 792-805

Lawrence, Reva C; Felson, David T; Helmick, Charles G; Arnold, Lesley M; Choi, Hyon; Deyo, Richard A; Gabriel, Sherine; Hirsch, Rosemarie; Hochberg, Marc C; Hunder, Gene G; Jordan, Joanne M; Katz, Jeffrey N; Kremers, Hilal Maradit; Wolfe, Frederick 2008. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis and rheumatism, 58 1, 26-35

Mease, Philip J; Russell, I Jon; Arnold, Lesley M; Florian, Hana; Young, James P; Martin, Susan A; Sharma, Uma 2008. A randomized, double-blind, placebo-controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia. The Journal of rheumatology, 35 3, 502-14

Mease, Phillip J; Arnold, Lesley M; Crofford, Leslie J; Williams, David A; Russell, I Jon; Humphrey, Louise; Abetz, Linda; Martin, Susan A 2008. Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises. Arthritis and rheumatism, 59 7, 952-60

Russell, I Jon; Mease, Philip J; Smith, Timothy R; Kajdasz, Daniel K; Wohlreich, Madelaine M; Detke, Michael J; Walker, Daniel J; Chappell, Amy S; Arnold, Lesley M 2008. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. Pain, 136 3, 432-44

Arnold, Lesley M 2007. Duloxetine and other antidepressants in the treatment of patients with fibromyalgia. Pain medicine (Malden, Mass.), 8 Suppl 2 , S63-74

Arnold, Lesley M; Goldenberg, Don L; Stanford, Sharon B; Lalonde, Justine K; Sandhu, H S; Keck, Paul E; Welge, Jeffrey A; Bishop, Fred; Stanford, Kevin E; Hess, Evelyn V; Hudson, James I 2007. Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. Arthritis and rheumatism, 56 4, 1336-44

Arnold, Lesley M; Pritchett, Yili Lu; D'Souza, Deborah N; Kajdasz, Daniel K; Iyengar, Smriti; Wernicke, Joachim F 2007. Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials. Journal of women's health (2002), 16 8, 1145-56

Mease, Philip; Arnold, Lesley M; Bennett, Robert; Boonen, Annelies; Buskila, Dan; Carville, Serena; Chappell, Amy; Choy, Ernest; Clauw, Daniel; Dadabhoy, Dina; Gendreau, Michael; Goldenberg, Don; Littlejohn, Geoffrey; Martin, Susan; Perera, Philip; Russell, I Jon; Simon, Lee; Spaeth, Michael; Williams, David; Crofford, Leslie 2007. Fibromyalgia syndrome. The Journal of rheumatology, 34 6, 1415-25

Pigott, Teresa A; Prakash, Apurva; Arnold, Lesley M; Aaronson, Scott T; Mallinckrodt, Craig H; Wohlreich, Madelaine M 2007. Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder. Current medical research and opinion, 23 6, 1303-18

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2007. Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania. Archives of general psychiatry, 64 1, 57-64

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2007. Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania. Archives of general psychiatry, 64 1, 57-64

Arnold, Lesley M 2006. Management of psychiatric comorbidity in fibromyalgia. Current psychiatry reports, 8 3, 241-5

Arnold, Lesley M 2006. Biology and therapy of fibromyalgia. New therapies in fibromyalgia. Arthritis research & therapy, 8 4, 212

Arnold, Lesley M; Hudson, James I; Keck, Paul E; Auchenbach, Megan B; Javaras, Kristin N; Hess, Evelyn V 2006. Comorbidity of fibromyalgia and psychiatric disorders. The Journal of clinical psychiatry, 67 8, 1219-25

Arnold, Lesley M 2005. The nature of painful and somatic complaints in depressive disorders. CNS spectrums, 10 12 Suppl 19, 4-5

Arnold, Lesley M; Rosen, Amy; Pritchett, Yili Lu; D'Souza, Deborah N; Goldstein, David J; Iyengar, Smriti; Wernicke, Joachim F 2005. A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. Pain, 119 1-3, 5-15

Mease, Philip J; Clauw, Daniel J; Arnold, Lesley M; Goldenberg, Don L; Witter, James; Williams, David A; Simon, Lee S; Strand, C Vibeke; Bramson, Candace; Martin, Susan; Wright, Timothy M; Littman, Bruce; Wernicke, J F; Gendreau, R Michael; Crofford, Leslie J 2005. Fibromyalgia syndrome. The Journal of rheumatology, 32 11, 2270-7

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2005. Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. Archives of general psychiatry, 62 8, 851-8

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2005. Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. Archives of general psychiatry, 62 8, 851-8

Arnold, Lesley M; Hudson, James I 2004. Comment on: Familial aggregation of depression in fibromyalgia: a community-based test of alternative hypotheses, Raphael et al., Pain 110 (2004) 449-460. Pain, 112 3, 409-10; author reply

Arnold, Lesley M; Hudson, James I; Hess, Evelyn V; Ware, Avis E; Fritz, Deborah A; Auchenbach, Megan B; Starck, Linsey O; Keck, Paul E 2004. Family study of fibromyalgia. Arthritis and rheumatism, 50 3, 944-52

Arnold, Lesley M; Keck, Paul E; Collins, Jacqueline; Wilson, Rodgers; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R; Strakowski, Stephen M 2004. Ethnicity and first-rank symptoms in patients with psychosis. Schizophrenia research, 67 2-3, 207-12

Arnold, Lesley M; Lu, Yili; Crofford, Leslie J; Wohlreich, Madelaine; Detke, Michael J; Iyengar, Smriti; Goldstein, David J 2004. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis and rheumatism, 50 9, 2974-84

Arnold, Lesley M; Strakowski, Stephen M; Schwiers, Michael L; Amicone, Jennifer; Fleck, David E; Corey, Kimberly B; Farrow, Jenni E 2004. Sex, ethnicity, and antipsychotic medication use in patients with psychosis. Schizophrenia research, 66 2-3, 169-75

Bennett, Aurora J; Arnold, Lesley M 2004. Use of a computerized evaluation system in a psychiatry clerkship. Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 28 3, 197-203

Hudson, James I; Arnold, Lesley M; Keck, Paul E; Auchenbach, Megan B; Pope, Harrison G 2004. Family study of fibromyalgia and affective spectrum disorder. Biological psychiatry, 56 11, 884-91

McElroy, Susan L; Shapira, Nathan A; Arnold, Lesley M; Keck, Paul E; Rosenthal, Norman R; Wu, Shu-Chen; Capece, Julie A; Fazzio, Lydia; Hudson, James I 2004. Topiramate in the long-term treatment of binge-eating disorder associated with obesity. The Journal of clinical psychiatry, 65 11, 1463-9

Arnold, Lesley M 2003. Gender differences in bipolar disorder. The Psychiatric clinics of North America, 26 3, 595-620

McElroy, Susan L; Arnold, Lesley M; Shapira, Nathan A; Keck, Paul E; Rosenthal, Norman R; Karim, M Rezaul; Kamin, Marc; Hudson, James I 2003. Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial. The American journal of psychiatry, 160 2, 255-61

Strakowski, Stephen M; Keck, Paul E; Arnold, Lesley M; Collins, Jacqueline; Wilson, Rodgers M; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R 2003. Ethnicity and diagnosis in patients with affective disorders. The Journal of clinical psychiatry, 64 7, 747-54

Arnold, Lesley M 2002. Phenomenology and therapeutic options for dermatotillomania. Expert review of neurotherapeutics, 2 5, 725-30

Arnold, Lesley M; Hess, Evelyn V; Hudson, James I; Welge, Jeffrey A; Berno, Sarah E; Keck, Paul E 2002. A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. The American journal of medicine, 112 3, 191-7

Arnold, Lesley M; McElroy, Susan L; Hudson, James I; Welge, Jeffrey A; Bennett, Aurora J; Keck, Paul E 2002. A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorder. The Journal of clinical psychiatry, 63 11, 1028-33

Arnold, Lesley M. 1999. A Case Series of Women With Postpartum-Onset Obsessive-Compulsive Disorder. Primary care companion to the Journal of clinical psychiatry, 1 4, 103-108

Arnold, Lesley M . Understanding fatigue in major depressive disorder and other medical disorders. Psychosomatics, 49 3, 185-90

Arnold, Lesley M; Blom, Thomas J; Welge, Jeffrey A; Mariutto, Elizabeth; Heller, Alicia . A randomized, placebo-controlled, double-blinded trial of duloxetine in the treatment of general fatigue in patients with chronic fatigue syndrome. Psychosomatics, 56 3, 242-53

Arnold, Lesley M; Crofford, Leslie J; Martin, Susan A; Young, James P; Sharma, Uma . The effect of anxiety and depression on improvements in pain in a randomized, controlled trial of pregabalin for treatment of fibromyalgia. Pain medicine (Malden, Mass.), 8 8, 633-8

Arnold, Lesley M; Hudson, James I; Wang, Fujun; Wohlreich, Madelaine M; Prakash, Apurva; Kajdasz, Daniel K; Chappell, Amy S . Comparisons of the efficacy and safety of duloxetine for the treatment of fibromyalgia in patients with versus without major depressive disorder. The Clinical journal of pain, 25 6, 461-8

Arnold, Lesley M; Leon, Teresa; Whalen, Ed; Barrett, Jeannette . Relationships among pain and depressive and anxiety symptoms in clinical trials of pregabalin in fibromyalgia. Psychosomatics, 51 6, 489-97

Arnold, Lesley M; Meyers, Adam L; Sunderajan, Prabha; Montano, C Brendan; Kass, Ethan; Trivedi, Madhukar; Wohlreich, Madelaine M . The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 20 4, 187-93

Arnold, Lesley M; Palmer, Robert H; Gendreau, R Michael; Chen, Wei . Relationships among pain, depressed mood, and global status in fibromyalgia patients: post hoc analyses of a randomized, placebo-controlled trial of milnacipran. Psychosomatics, 53 4, 371-9

Arnold, Lesley M; Zhang, Shuyu; Pangallo, Beth A . Efficacy and safety of duloxetine 30 mg/d in patients with fibromyalgia: a randomized, double-blind, placebo-controlled study. The Clinical journal of pain, 28 9, 775-81

Bennett, Aurora J; Arnold, Lesley M; Welge, Jeffrey A . Use of standardized patients during a psychiatry clerkship. Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 30 3, 185-90

Bennett, Aurora J; Roman, Brenda; Arnold, Lesley M; Kay, Jerald; Goldenhar, Linda M . Professionalism deficits among medical students: models of identification and intervention. Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 29 5, 426-32

Chandran, Arthi B; Coon, Cheryl D; Martin, Susan A; McLeod, Lori D; Coles, Theresa M; Arnold, Lesley M . Sphygmomanometry-evoked allodynia in chronic pain patients with and without fibromyalgia. Nursing research, 61 5, 363-8

Mohs, Richard; Mease, Philip; Arnold, Lesley M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M . The effect of duloxetine treatment on cognition in patients with fibromyalgia. Psychosomatic medicine, 74 6, 628-34