Education/CredentialsFellowship: University of Utah (Medical and Public Health Laboratory Microbiology)PhD: University of Cincinnati Medical Center (Pathobiology and Molecular Medicine) Contact Information French Hall Office 513-558-4704 Email powersmg@ucmail.uc.edu Peer Reviewed Publications Powers-Fletcher M and Barker A 2016. Matrix Assisted Laser Desorption Ionization Time of Flight (MALDITOF) for Microorganism Identification Clin Micro Pro Handbook, Fourth Edition ASM Press, Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Molecular Diagnostic Testing for Aspergillus. Journal of clinical microbiology, 54 11, 2655-2660Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Nonculture Diagnostics in Fungal Disease. Infectious disease clinics of North America, 30 1, 37-49Powers-Fletcher, Margaret V; Kendall, Brian A; Griffin, Allen T; Hanson, Kimberly E 2016. Filamentous Fungi Microbiology spectrum, 4 3, Walker, Brandon; Powers-Fletcher, Margaret V; Schmidt, Robert L; Hanson, Kimberly E 2016. Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture-Directed Therapy for Management of Suspected Candidemia. Journal of clinical microbiology, 54 3, 718-26Powers-Fletcher MV, Couturier MR 2015. Non-Helicobacter pylori Helicobacter species associated with human disease: a primer for the clinical microbiology laboratory Clinical Microbiology Newsletter, 37 12, Krishnan, Karthik; Feng, Xizhi; Powers-Fletcher, Margaret V; Bick, Gregory; Richie, Daryl L; Woollett, Laura A; Askew, David S 2013. Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus. Eukaryotic cell, 12 4, 512-9Powers-Fletcher, Margaret V; Feng, Xizhi; Krishnan, Karthik; Askew, David S 2013. Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity. PloS one, 8 6, e66741Feng, Xizhi; Krishnan, Karthik; Richie, Daryl L; Aimanianda, Vishukumar; Hartl, Lukas; Grahl, Nora; Powers-Fletcher, Margaret V; Zhang, Minlu; Fuller, Kevin K; Nierman, William C; Lu, Long Jason; Latgé, Jean-Paul; Woollett, Laura; Newman, Simon L; Cramer, Robert A; Rhodes, Judith C; Askew, David S 2011. HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. PLoS pathogens, 7 10, e1002330Powers-Fletcher M 2011. A Review of the Biology and the Laboratory Diagnosis of Treponema pallidum Infections Journal of Continuing Education Topics & Issues, 13 3, 80-93Powers-Fletcher, Margaret V; Jambunathan, Kalyani; Brewer, Jordan L; Krishnan, Karthik; Feng, Xizhi; Galande, Amit K; Askew, David S 2011. Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus. PloS one, 6 12, e28865Richie, Daryl L; Feng, Xizhi; Hartl, Lukas; Aimanianda, Vishukumar; Krishnan, Karthik; Powers-Fletcher, Margaret V; Watson, Douglas S; Galande, Amit K; White, Stephanie M; Willett, Taryn; Latgé, Jean-Paul; Rhodes, Judith C; Askew, David S . The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR). Virulence, 2 1, 12-21
Peer Reviewed Publications Powers-Fletcher M and Barker A 2016. Matrix Assisted Laser Desorption Ionization Time of Flight (MALDITOF) for Microorganism Identification Clin Micro Pro Handbook, Fourth Edition ASM Press, Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Molecular Diagnostic Testing for Aspergillus. Journal of clinical microbiology, 54 11, 2655-2660Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Nonculture Diagnostics in Fungal Disease. Infectious disease clinics of North America, 30 1, 37-49Powers-Fletcher, Margaret V; Kendall, Brian A; Griffin, Allen T; Hanson, Kimberly E 2016. Filamentous Fungi Microbiology spectrum, 4 3, Walker, Brandon; Powers-Fletcher, Margaret V; Schmidt, Robert L; Hanson, Kimberly E 2016. Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture-Directed Therapy for Management of Suspected Candidemia. Journal of clinical microbiology, 54 3, 718-26Powers-Fletcher MV, Couturier MR 2015. Non-Helicobacter pylori Helicobacter species associated with human disease: a primer for the clinical microbiology laboratory Clinical Microbiology Newsletter, 37 12, Krishnan, Karthik; Feng, Xizhi; Powers-Fletcher, Margaret V; Bick, Gregory; Richie, Daryl L; Woollett, Laura A; Askew, David S 2013. Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus. Eukaryotic cell, 12 4, 512-9Powers-Fletcher, Margaret V; Feng, Xizhi; Krishnan, Karthik; Askew, David S 2013. Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity. PloS one, 8 6, e66741Feng, Xizhi; Krishnan, Karthik; Richie, Daryl L; Aimanianda, Vishukumar; Hartl, Lukas; Grahl, Nora; Powers-Fletcher, Margaret V; Zhang, Minlu; Fuller, Kevin K; Nierman, William C; Lu, Long Jason; Latgé, Jean-Paul; Woollett, Laura; Newman, Simon L; Cramer, Robert A; Rhodes, Judith C; Askew, David S 2011. HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. PLoS pathogens, 7 10, e1002330Powers-Fletcher M 2011. A Review of the Biology and the Laboratory Diagnosis of Treponema pallidum Infections Journal of Continuing Education Topics & Issues, 13 3, 80-93Powers-Fletcher, Margaret V; Jambunathan, Kalyani; Brewer, Jordan L; Krishnan, Karthik; Feng, Xizhi; Galande, Amit K; Askew, David S 2011. Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus. PloS one, 6 12, e28865Richie, Daryl L; Feng, Xizhi; Hartl, Lukas; Aimanianda, Vishukumar; Krishnan, Karthik; Powers-Fletcher, Margaret V; Watson, Douglas S; Galande, Amit K; White, Stephanie M; Willett, Taryn; Latgé, Jean-Paul; Rhodes, Judith C; Askew, David S . The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR). Virulence, 2 1, 12-21
Powers-Fletcher M and Barker A 2016. Matrix Assisted Laser Desorption Ionization Time of Flight (MALDITOF) for Microorganism Identification Clin Micro Pro Handbook, Fourth Edition ASM Press, Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Molecular Diagnostic Testing for Aspergillus. Journal of clinical microbiology, 54 11, 2655-2660Powers-Fletcher, Margaret V; Hanson, Kimberly E 2016. Nonculture Diagnostics in Fungal Disease. Infectious disease clinics of North America, 30 1, 37-49Powers-Fletcher, Margaret V; Kendall, Brian A; Griffin, Allen T; Hanson, Kimberly E 2016. Filamentous Fungi Microbiology spectrum, 4 3, Walker, Brandon; Powers-Fletcher, Margaret V; Schmidt, Robert L; Hanson, Kimberly E 2016. Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture-Directed Therapy for Management of Suspected Candidemia. Journal of clinical microbiology, 54 3, 718-26Powers-Fletcher MV, Couturier MR 2015. Non-Helicobacter pylori Helicobacter species associated with human disease: a primer for the clinical microbiology laboratory Clinical Microbiology Newsletter, 37 12, Krishnan, Karthik; Feng, Xizhi; Powers-Fletcher, Margaret V; Bick, Gregory; Richie, Daryl L; Woollett, Laura A; Askew, David S 2013. Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus. Eukaryotic cell, 12 4, 512-9Powers-Fletcher, Margaret V; Feng, Xizhi; Krishnan, Karthik; Askew, David S 2013. Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity. PloS one, 8 6, e66741Feng, Xizhi; Krishnan, Karthik; Richie, Daryl L; Aimanianda, Vishukumar; Hartl, Lukas; Grahl, Nora; Powers-Fletcher, Margaret V; Zhang, Minlu; Fuller, Kevin K; Nierman, William C; Lu, Long Jason; Latgé, Jean-Paul; Woollett, Laura; Newman, Simon L; Cramer, Robert A; Rhodes, Judith C; Askew, David S 2011. HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. PLoS pathogens, 7 10, e1002330Powers-Fletcher M 2011. A Review of the Biology and the Laboratory Diagnosis of Treponema pallidum Infections Journal of Continuing Education Topics & Issues, 13 3, 80-93Powers-Fletcher, Margaret V; Jambunathan, Kalyani; Brewer, Jordan L; Krishnan, Karthik; Feng, Xizhi; Galande, Amit K; Askew, David S 2011. Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus. PloS one, 6 12, e28865Richie, Daryl L; Feng, Xizhi; Hartl, Lukas; Aimanianda, Vishukumar; Krishnan, Karthik; Powers-Fletcher, Margaret V; Watson, Douglas S; Galande, Amit K; White, Stephanie M; Willett, Taryn; Latgé, Jean-Paul; Rhodes, Judith C; Askew, David S . The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR). Virulence, 2 1, 12-21