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Photo of Jason C. Gardner

Jason C. Gardner

Research Assistant Professor

Internal Medicine | College of Medicine

  • Fellowship: University of Cincinnati (Postdoctornal)
  • Doctoral Degree: University of Cincinnati (Pathobiology and Molecular Medicine)
  • Bachelor's Degree: Indiana University (Microbiology)
Contact Information

Peer Reviewed Publications

Hasegawa, Yoshihiro; Franks, Jennifer M; Tanaka, Yusuke; Uehara, Yasuaki; Read, David F; Williams, Claire; Srivatsan, Sanjay; Pitstick, Lori B; Nikolaidis, Nikolaos M; Shaver, Ciara M; Wu, Huixing; Gardner, Jason C; Osterburg, Andrew R; Yu, Jane J; Kopras, Elizabeth J; Teitelbaum, Steven L; Wikenheiser-Brokamp, Kathryn A; Trapnell, Cole; McCormack, Francis X 2023. Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis. bioRxiv : the preprint server for biology, ,

Noel, John G; Ramser, Seth W; Pitstick, Lori; Goetzman, Holly S; Dale, Elizabeth L; Potter, Andrew; Adam, Mike; Potter, S Steven; Gardner, Jason C 2023. IL-1/MyD88-Dependent G-CSF and IL-6 Secretion Mediates Postburn Anemia. Journal of immunology (Baltimore, Md. : 1950), 210 7, 972-980

Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205

Noel, John G; Ramser, Seth W; Pitstick, Lori; Bonamer, John P; Mackenzie, Bryan; Seu, Katie G; Kalfa, Theodosia A; Cancelas, Jose A; Gardner, Jason C 2022. M-CSF supports medullary erythropoiesis and erythroid iron demand following burn injury through its activity on homeostatic iron recycling. Scientific reports, 12 1, 1235

Chowdhury, Debabrata; Gardner, Jason C; Satpati, Abhijit; Nookala, Suba; Mukundan, Santhosh; Porollo, Aleksey; Landero Figueroa, Julio A; Subramanian Vignesh, Kavitha 2021. Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity. Frontiers in immunology, 12 , 755961

Nikolaidis, Nikolaos M; Noel, John G; Pitstick, Lori B; Gardner, Jason C; Uehara, Yasuaki; Wu, Huixing; Saito, Atsushi; Lewnard, Kara E; Liu, Huan; White, Mitchell R; Hartshorn, Kevan L; McCormack, Francis X 2017. Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection. Proceedings of the National Academy of Sciences of the United States of America, ,

Noel, John G; Ramser, Benjamin J; Cancelas, Jose A; McCormack, Francis X; Gardner, Jason C 2017. Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. Experimental hematology, 56 , 16-30

Gardner, J. C.; Wu, H.; Noel, J. G.; Ramser, B. J.; Pitstick, L.; Saito, A.; Nikolaidis, N. M.; McCormack, F. X. 2016. Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function Am J Physiol Lung Cell Mol Physiol, 310 9 , L868-79

Pasula, R.; Azad, A. K.; Gardner, J. C.; Schlesinger, L. S.; McCormack, F. X. 2015. Keratinocyte growth factor administration attenuates murine pulmonary mycobacterium tuberculosis infection through granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent macrophage activation and phagolysosome fusion J Biol Chem, 290 11 , 7151-9

Saito, A.; Nikolaidis, N. M.; Amlal, H.; Uehara, Y.; Gardner, J. C.; LaSance, K.; Pitstick, L. B.; Bridges, J. P.; Wikenheiser-Brokamp, K. A.; McGraw, D. W.; Woods, J. C.; Sabbagh, Y.; Schiavi, S. C.; Altinisik, G.; Jakopovic, M.; Inoue, Y.; McCormack, F. X. 2015. Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment Sci Transl Med, 7 313 , 313ra181

Gardner, J. C.; Noel, J. G.; Nikolaidis, N. M.; Karns, R.; Aronow, B. J.; Ogle, C. K.; McCormack, F. X. 2014. G-CSF drives a posttraumatic immune program that protects the host from infection J Immunol, 192 5 , 2405-17

Healy, D. P.; Sombun, A. D.; Gardner, J. C.; Good, K.; Durkee, P. J.; Toner, L.; Rieman, M. T.; Neely, A. N.; Kagan, R. J. 2011. Pharmacokinetics of colistin in an adolescent boy with extensive burn injury J Burn Care Res, 32 1 , e7-11

Dugan, A. L.; Gregerson, K. A.; Neely, A.; Gardner, J.; Noel, G. J.; Babcock, G. F.; Horseman, N. D. 2010. Mice treated with a benzodiazepine had an improved survival rate following Pseudomonas aeruginosa infection J Burn Care Res, 31 1 , 1-12

Neely, A. N.; Gardner, J.; Durkee, P.; Warden, G. D.; Greenhalgh, D. G.; Gallagher, J. J.; Herndon, D. N.; Tompkins, R. G.; Kagan, R. J. 2009. Are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics? J Burn Care Res, 30 1 , 19-29

Osterburg, A.; Gardner, J.; Hyon, S. H.; Neely, A.; Babcock, G. 2009. Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) Clin Microbiol Infect, 15 4 , 341-6

Supp, D. M.; Gardner, J.; Klingenberg, J. M.; Neely, A. N. 2009. Antibiotic resistance in clinical isolates of Acinetobacter baumannii, Pseudomonas aeruginosa, and Staphylococcus aureus does not impact sensitivity to human beta defensin 4 Burns, 35 7 , 949-55

Tschop, J.; Martignoni, A.; Reid, M. D.; Adediran, S. G.; Gardner, J.; Noel, G. J.; Ogle, C. K.; Neely, A. N.; Caldwell, C. C. 2009. Differential immunological phenotypes are exhibited after scald and flame burns Shock, 31 2 , 157-63

DiGiandomenico, A.; Rao, J.; Harcher, K.; Zaidi, T. S.; Gardner, J.; Neely, A. N.; Pier, G. B.; Goldberg, J. B. 2007. Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections Proc Natl Acad Sci U S A, 104 11 , 4624-9

Healy, Daniel P.; Gardner, Jason C.; Puthoff, Barbara K.; Kagan, Richard J.; Neely, Alice N. 2007. Antibiotic-mediated bacterial filamentation: A potentially important laboratory phenomenon Clinical Microbiology Newsletter, 29 3 , 22-24

Smiley, A. K.; Gardner, J.; Klingenberg, J. M.; Neely, A. N.; Supp, D. M. 2007. Expression of human beta defensin 4 in genetically modified keratinocytes enhances antimicrobial activity J Burn Care Res, 28 1 , 127-32

Neely, A. N.; Regnold, L. A.; Hayes, S.; Gardner, J.; Cahill, T. J. 2006. Redesign of portable suction equipment cases: an engineering approach to a disinfection problem Am J Infect Control, 34 5 , 281-4

Neely, A. N.; Mayes, T.; Gardner, J.; Kagan, R. J.; Gottschlich, M. M. 2006. A microbiologic study of enteral feeding hang time in a burn hospital: can feeding costs be reduced without compromising patient safety? Nutr Clin Pract, 21 6 , 610-6

Neely, A. N.; Clendening, C. E.; Gardner, J.; Greenhalgh, D. G. 2000. Gelatinase activities in wounds of healing-impaired mice versus wounds of non-healing-impaired mice J Burn Care Rehabil, 21 5 , 395-402

Neely, A. N.; Clendening, C. E.; Gardner, J.; Greenhalgh, D. G.; Warden, G. D. 1999. Gelatinase activity in keloids and hypertrophic scars Wound Repair Regen, 7 3 , 166-71

Neely, A. N.; Brown, R. L.; Clendening, C. E.; Orloff, M. M.; Gardner, J.; Greenhalgh, D. G. 1997. Proteolytic activity in human burn wounds Wound Repair Regen, 5 4 , 302-9