Skip to main content
Photo of Huixing Wu

Huixing Wu

Principal Research Asst

Internal Medicine | College of Medicine

Contact Information

Peer Reviewed Publications

Gardner, Jason C; Wu, Huixing; Noel, John G; Ramser, Benjamin J; Pitstick, Lori; Saito, Atsushi; Nikolaidis, Nikolaos M; McCormack, Francis X 2016. Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function. American journal of physiology. Lung cellular and molecular physiology, 310 9, L868-79

Goh, Boon Chong; Wu, Huixing; Rynkiewicz, Michael J; Schulten, Klaus; Seaton, Barbara A; McCormack, Francis X 2016. Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry, 55 26, 3692-701

Shang, Feifei; Rynkiewicz, Michael J; McCormack, Francis X; Wu, Huixing; Cafarella, Tanya M; Head, James F; Seaton, Barbara A 2011. Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change. The Journal of biological chemistry, 286 1, 757-65

Wu, Huixing; Suzuki, Takuji; Carey, Brenna; Trapnell, Bruce C; McCormack, Francis X 2011. Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages. The Journal of biological chemistry, 286 17, 14932-40

Kuzmenko, Alexander I; Wu, Huixing; McCormack, Francis X 2006. Pulmonary collectins selectively permeabilize model bacterial membranes containing rough lipopolysaccharide. Biochemistry, 45 8, 2679-85

Ryan, Marnie A; Akinbi, Henry T; Serrano, Alicia G; Perez-Gil, Jesus; Wu, Huixing; McCormack, Francis X; Weaver, Timothy E 2006. Antimicrobial activity of native and synthetic surfactant protein B peptides. Journal of immunology (Baltimore, Md. : 1950), 176 1, 416-25

Kuzmenko, Alexander I; Wu, Huixing; Wan, Sijue; McCormack, Francis X 2005. Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid. The Journal of biological chemistry, 280 27, 25913-9

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A 2004. Interactions of pulmonary collectins with Bordetella bronchiseptica and Bordetella pertussis lipopolysaccharide elucidate the structural basis of their antimicrobial activities. Infection and immunity, 72 12, 7124-30

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A 2004. Bordetella pertussis lipopolysaccharide resists the bactericidal effects of pulmonary surfactant protein A. Journal of immunology (Baltimore, Md. : 1950), 173 3, 1959-65

McCormack, Francis X; Gibbons, Reta; Ward, Susan R; Kuzmenko, Alexander; Wu, Huixing; Deepe, George S 2003. Macrophage-independent fungicidal action of the pulmonary collectins. The Journal of biological chemistry, 278 38, 36250-6

Wu, Huixing; Kuzmenko, Alexander; Wan, Sijue; Schaffer, Lyndsay; Weiss, Alison; Fisher, James H; Kim, Kwang Sik; McCormack, Francis X 2003. Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability. The Journal of clinical investigation, 111 10, 1589-602

Palaniyar, Nades; Zhang, Liquian; Kuzmenko, Alexander; Ikegami, Machiko; Wan, Sijue; Wu, Huixing; Korfhagen, Thomas R; Whitsett, Jeffrey A; McCormack, Francis X 2002. The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo. The Journal of biological chemistry, 277 30, 26971-9