Education/CredentialsFellowship: Johns Hopkins Hospital (Hematology)Fellowship: Johns Hopkins Hospital (Hematology)Fellowship: Case Western Reserve University (Critical Care)Chief Resident: Case Western Reserve UniversityInternship: Case Western Reserve University (Internal Medicine)Master's Degree: Tulane University School of Public Health (Medicine and Health Systems Mangement)Medical Degree: Tulane University School of Medicine Bachelor's Degree: University of Notre Dame (Pre-Professional Studies and Political Science) Board Certifications & LicensesAmerican Board of Internal Medicine (Critical Care Medicine) (Certification Date: 2020-12-15)American Board of Internal Medicine (Hematology) (Certification Date: 2019-10-25)American Board of Internal Medicine (Certification Date: 2015-08-11) SpecialtiesCritical Care MedicineHematologyInternal Medicine Contact Information Vontz Center Office 513-558-2115 Email hamblebc@ucmail.uc.edu Clinical Interests Critical Care MedicineHematology and OncologyLeukemiaAcute Lymphocytic LeukemiaAcute Myeloid LeukemiaAmyloidosisCastleman DiseaseChronic Lymphocytic LeukemiaChronic Myelogenous LeukemiaLymphadenopathyLymphomaM ProteinMacrocytosisMediastinal AdenopathyMonoclonal gammopathyMonoclonal proteinM-SpikeMycosis FugoidesMyelodysplastic SyndromeMyelomaMyeloproliferative DisorderParaproteinemiaPlasma Cell DisorderPlasminogen Activator Inhibitor 1Polycythemia veraProteinuriaSideroblastic anemiaT-cell lymphoma Peer Reviewed Publications Coriu, Daniel; Dirzu, Noemi; Zimta, Alina-Andreea; Hambley, Bryan C; Liu, Xiaojing; Nemes, Laszlo; Ghiaur, Gabriel; Mahlangu, Johny; Tomuleasa, Ciprian 2022. Editorial: Modern Approaches to Hemophilia Management: Gene Therapy and Beyond. Frontiers in medicine, 9 , 859710Murdock, H Moses; Kim, Haesook T; Denlinger, Nathan; Vachhani, Pankit; Hambley, Bryan; Manning, Bryan S; Gier, Shannon; Cho, Christina; Tsai, Harrison K; McCurdy, Shannon; Ho, Vincent T; Koreth, John; Soiffer, Robert J; Ritz, Jerome; Carroll, Martin P; Vasu, Sumithira; Perales, Miguel-Angel; Wang, Eunice S; Gondek, Lukasz P; Devine, Steven; Alyea, Edwin P; Lindsley, R Coleman; Gibson, Christopher J 2022. Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML. Blood, 139 24, 3546-3557VanDommelen, Kyle; Omer, Zulfa; Hambley, Bryan C; Stefaniuk, Catherine M 2022. Reversal of life-threatening bleeding with protamine sulfate in a patient with plasma cell leukemia. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 33 7, 425-428Hambley, Bryan C; Tomuleasa, Ciprian; Ghiaur, Gabriel 2021. Coagulopathy in Acute Promyelocytic Leukemia: Can We Go Beyond Supportive Care? Frontiers in medicine, 8 , 722614Safi, Salahuddin; Shanbhag, Satish; Hambley, Bryan C; Merrill, Samuel A 2021. Systems controls are needed to reduce mistaken tests for hemophagocytic lymphohistiocytosis, results of a prospective quality-improvement cohort study. Medicine, 100 26, e26509Trybula, Marcus; Wang, Diping; Baumann, Lauren; Pritts, Timothy A; Hambley, Bryan C 2021. Rhizopus microsporus typhlitis in a patient with acute myelogenous leukemia. Clinical case reports, 9 6, e04290Alex Ambinder, Bryan Hambley, Satish Shanbhag, and Sam Merrill 2019. Ibrutinib-associated hemophagocytic lymphohistiocytosis: A case series from Johns Hopkins American Journal of Hematology, , Bryan Hambley, Kelly Norsworthy, Jagar Jasem, Jacquelyn Zimmerman et al. 2019. Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction Leukemia Research, , Eric Gehrie et al. 2019. One-unit compared to two-unit platelet transfusions for adult oncology outpatients Vox Sanguinis, , Bryan Hambley, Paolo Caimi, and Basem William 2016. Bortezomib for the treatment of mantle cell lymphoma: an update Therapeutic Advances in Hematology, ,
Clinical Interests Critical Care MedicineHematology and OncologyLeukemiaAcute Lymphocytic LeukemiaAcute Myeloid LeukemiaAmyloidosisCastleman DiseaseChronic Lymphocytic LeukemiaChronic Myelogenous LeukemiaLymphadenopathyLymphomaM ProteinMacrocytosisMediastinal AdenopathyMonoclonal gammopathyMonoclonal proteinM-SpikeMycosis FugoidesMyelodysplastic SyndromeMyelomaMyeloproliferative DisorderParaproteinemiaPlasma Cell DisorderPlasminogen Activator Inhibitor 1Polycythemia veraProteinuriaSideroblastic anemiaT-cell lymphoma
Peer Reviewed Publications Coriu, Daniel; Dirzu, Noemi; Zimta, Alina-Andreea; Hambley, Bryan C; Liu, Xiaojing; Nemes, Laszlo; Ghiaur, Gabriel; Mahlangu, Johny; Tomuleasa, Ciprian 2022. Editorial: Modern Approaches to Hemophilia Management: Gene Therapy and Beyond. Frontiers in medicine, 9 , 859710Murdock, H Moses; Kim, Haesook T; Denlinger, Nathan; Vachhani, Pankit; Hambley, Bryan; Manning, Bryan S; Gier, Shannon; Cho, Christina; Tsai, Harrison K; McCurdy, Shannon; Ho, Vincent T; Koreth, John; Soiffer, Robert J; Ritz, Jerome; Carroll, Martin P; Vasu, Sumithira; Perales, Miguel-Angel; Wang, Eunice S; Gondek, Lukasz P; Devine, Steven; Alyea, Edwin P; Lindsley, R Coleman; Gibson, Christopher J 2022. Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML. Blood, 139 24, 3546-3557VanDommelen, Kyle; Omer, Zulfa; Hambley, Bryan C; Stefaniuk, Catherine M 2022. Reversal of life-threatening bleeding with protamine sulfate in a patient with plasma cell leukemia. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 33 7, 425-428Hambley, Bryan C; Tomuleasa, Ciprian; Ghiaur, Gabriel 2021. Coagulopathy in Acute Promyelocytic Leukemia: Can We Go Beyond Supportive Care? Frontiers in medicine, 8 , 722614Safi, Salahuddin; Shanbhag, Satish; Hambley, Bryan C; Merrill, Samuel A 2021. Systems controls are needed to reduce mistaken tests for hemophagocytic lymphohistiocytosis, results of a prospective quality-improvement cohort study. Medicine, 100 26, e26509Trybula, Marcus; Wang, Diping; Baumann, Lauren; Pritts, Timothy A; Hambley, Bryan C 2021. Rhizopus microsporus typhlitis in a patient with acute myelogenous leukemia. Clinical case reports, 9 6, e04290Alex Ambinder, Bryan Hambley, Satish Shanbhag, and Sam Merrill 2019. Ibrutinib-associated hemophagocytic lymphohistiocytosis: A case series from Johns Hopkins American Journal of Hematology, , Bryan Hambley, Kelly Norsworthy, Jagar Jasem, Jacquelyn Zimmerman et al. 2019. Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction Leukemia Research, , Eric Gehrie et al. 2019. One-unit compared to two-unit platelet transfusions for adult oncology outpatients Vox Sanguinis, , Bryan Hambley, Paolo Caimi, and Basem William 2016. Bortezomib for the treatment of mantle cell lymphoma: an update Therapeutic Advances in Hematology, ,
Coriu, Daniel; Dirzu, Noemi; Zimta, Alina-Andreea; Hambley, Bryan C; Liu, Xiaojing; Nemes, Laszlo; Ghiaur, Gabriel; Mahlangu, Johny; Tomuleasa, Ciprian 2022. Editorial: Modern Approaches to Hemophilia Management: Gene Therapy and Beyond. Frontiers in medicine, 9 , 859710Murdock, H Moses; Kim, Haesook T; Denlinger, Nathan; Vachhani, Pankit; Hambley, Bryan; Manning, Bryan S; Gier, Shannon; Cho, Christina; Tsai, Harrison K; McCurdy, Shannon; Ho, Vincent T; Koreth, John; Soiffer, Robert J; Ritz, Jerome; Carroll, Martin P; Vasu, Sumithira; Perales, Miguel-Angel; Wang, Eunice S; Gondek, Lukasz P; Devine, Steven; Alyea, Edwin P; Lindsley, R Coleman; Gibson, Christopher J 2022. Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML. Blood, 139 24, 3546-3557VanDommelen, Kyle; Omer, Zulfa; Hambley, Bryan C; Stefaniuk, Catherine M 2022. Reversal of life-threatening bleeding with protamine sulfate in a patient with plasma cell leukemia. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 33 7, 425-428Hambley, Bryan C; Tomuleasa, Ciprian; Ghiaur, Gabriel 2021. Coagulopathy in Acute Promyelocytic Leukemia: Can We Go Beyond Supportive Care? Frontiers in medicine, 8 , 722614Safi, Salahuddin; Shanbhag, Satish; Hambley, Bryan C; Merrill, Samuel A 2021. Systems controls are needed to reduce mistaken tests for hemophagocytic lymphohistiocytosis, results of a prospective quality-improvement cohort study. Medicine, 100 26, e26509Trybula, Marcus; Wang, Diping; Baumann, Lauren; Pritts, Timothy A; Hambley, Bryan C 2021. Rhizopus microsporus typhlitis in a patient with acute myelogenous leukemia. Clinical case reports, 9 6, e04290Alex Ambinder, Bryan Hambley, Satish Shanbhag, and Sam Merrill 2019. Ibrutinib-associated hemophagocytic lymphohistiocytosis: A case series from Johns Hopkins American Journal of Hematology, , Bryan Hambley, Kelly Norsworthy, Jagar Jasem, Jacquelyn Zimmerman et al. 2019. Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction Leukemia Research, , Eric Gehrie et al. 2019. One-unit compared to two-unit platelet transfusions for adult oncology outpatients Vox Sanguinis, , Bryan Hambley, Paolo Caimi, and Basem William 2016. Bortezomib for the treatment of mantle cell lymphoma: an update Therapeutic Advances in Hematology, ,