Education/CredentialsPh.D.: University of Guelph (Statistics)M.S.: Dalhousie University (Statistics)M.S.: Zhejiang University (Mathematical statistics)B.S.: Hunan Normal University (Mathematics) Contact Information Kettering Lab Complex 104 Office 513-558-0229 Email xiecn@ucmail.uc.edu Research InterestsMy research interests include 1) clinical trials, 2) statistical genetics: next generation sequencing, Genome-wide association study, NDA methylation, gene environmental interaction, 3) statistical methodology: survival models, multiple testing, hierarchical generalized linear models, nonparametric methods, longitudinal data and multivariate statistical analysis. Peer Reviewed Publications An, Yu; Fnu, Gulimirerouzi; Xie, Changchun; Weber, Georg F 2023. Meta-analysis of Osteopontin splice variants in cancer. BMC cancer, 23 1, 373Connelly, Katherine M; Winslow, Stephanie E; Smith, Justin; Ahmad, Saad S; Xie, Changchun; Hinckley, William R; Gottula, Adam L; Lane, Bennett H 2023. Management of patients with impella devices or intra-aortic balloon pumps during helicopter air ambulance transport in observational data. Perfusion, , 2676591231158273Lewis, Clayton S; Bari, Khurram; Xie, Changchun; Sherman, Kenneth E; Vasse, Marc; Van Dreden, Patrick; Bogdanov, Vladimir Y 2023. Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease. BMC gastroenterology, 23 1, 65Wang, Kesheng; Shafique, Saima; Xiao, Danqing; Walter, Suzy Mascaro; Liu, Ying; Piamjariyakul, Ubolrat; Xie, Changchun 2023. Repeated measures analysis of opioid use disorder treatment on clinical opiate withdrawal scale in a randomized clinical trial: sex differences. Journal of addictive diseases, , 1-12Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2023. Gestational exposure to organophosphate esters and infant anthropometric measures in the first 4 weeks after birth. The Science of the total environment, 857 Pt 1, 159322Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2023. Associations of gestational exposure to organophosphate esters with gestational age and neonatal anthropometric measures: The HOME study. Environmental pollution (Barking, Essex : 1987), 316 Pt 1, 120516Wang, Kesheng; DiChiacchio, Toni; Fang, Wei; Lander, Laura; Feinberg, Judith; Xie, Changchun; Winstanley, Erin L; Ubolrat Piamjariyakul, 2022. Longitudinal study of impact of medication for opioid use disorder on Hamilton Depression Rating Scale. Journal of affective disorders, 297 , 148-155Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Werner, Erika; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2022. Maternal urinary OPE metabolite concentrations and blood pressure during pregnancy: The HOME study. Environmental research, 207 , 112220Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2022. Maternal urinary organophosphate ester metabolite concentrations and glucose tolerance during pregnancy: The HOME Study. International journal of hygiene and environmental health, 245 , 114026Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M 2021. Air pollution and the pandemic: Long-term PM2.5 exposure and disease severity in COVID-19 patients. Respirology (Carlton, Vic.), 26 12, 1181-1187Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M 2021. Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients. Respiratory medicine, 178 , 106313Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Hoofnagle, Andy; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Yolton, Kimberly; Chen, Aimin 2021. Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones. American journal of epidemiology, 190 9, 1793-1802Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Chen, Aimin; Yolton, Kimberly 2021. Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study. Neurotoxicology, 87 , 149-155Ryder, Justin R; Xu, Peixin; Nadeau, Kristen J; Kelsey, Megan M; Xie, Changchun; Jenkins, Todd; Inge, Thomas H; Bjornstad, Petter 2021. Effect of surgical versus medical therapy on estimated cardiovascular event risk among adolescents with type 2 diabetes and severe obesity. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 17 1, 23-33Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Dietrich, Kim N; Braun, Joseph M; Webster, Glenys M; Calafat, Antonia M; Lanphear, Bruce P; Chen, Aimin 2021. Childhood exposure to per- and polyfluoroalkyl substances (PFAS) and neurobehavioral domains in children at age 8 years. Neurotoxicology and teratology, 88 , 107022Wang, Kesheng; Xu, Chun; Smith, Amanda; Xiao, Danqing; Navia, R Osvaldo; Lu, Yongke; Xie, Changchun; Piamjariyakul, Ubolrat 2021. Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Progress in neuro-psychopharmacology & biological psychiatry, 111 , 110393Xu, Zongli; Xie, Changchun; Taylor, Jack A; Niu, Liang 2021. ipDMR: identification of differentially methylated regions with interval P-values. Bioinformatics (Oxford, England), 37 5, 711-713Abdel Karim, Nagla; Khaddasn, Sinan; Shehata, Mahmoud; Mostafa, Ahmed; Magdy, Mohamed; Eldessouki, Ihab; Xie, Changchun; Benzequene, Sadia 2020. Stenting in Non-Small Cell Lung Cancer: How Does It Affect the Outcomes? Asian Pacific journal of cancer prevention : APJCP, 21 1, 175-178Bjornstad, Petter; Hughan, Kara; Kelsey, Megan M; Shah, Amy S; Lynch, Jane; Nehus, Edward; Mitsnefes, Mark; Jenkins, Todd; Xu, Peixin; Xie, Changchun; Inge, Thomas; Nadeau, Kristen 2020. Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes. Diabetes care, 43 1, 187-195Derderian, S Christopher; Dewberry, Lindel C; Patten, Luke; Sitzman, Thomas J; Kaizer, Alexander M; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Mitchell, James E; Inge, Thomas 2020. Excess skin problems among adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 8, 993-998Derderian, S Christopher; Patten, Luke; Kaizer, Alexander M; Inge, Thomas H; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Dewberry, Lindel C; Sitzman, Thomas J 2020. Body contouring in adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 1, 137-142Kim, Stephani S; Xu, Xijin; Zhang, Yuling; Zheng, Xiangbin; Liu, Rongju; Dietrich, Kim N; Reponen, Tiina; Xie, Changchun; Sucharew, Heidi; Huo, Xia; Chen, Aimin 2020. Birth outcomes associated with maternal exposure to metals from informal electronic waste recycling in Guiyu, China. Environment international, 137 , 105580Percy, Zana; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Lanphear, Bruce P; Yolton, Kimberly; Vuong, Ann M; Cecil, Kim M; Braun, Joseph M; Xie, Changchun; Chen, Aimin 2020. Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out. Chemosphere, 239 , 124701Percy, Zana; Vuong, Ann M; Ospina, Maria; Calafat, Antonia M; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Xie, Changchun; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Yolton, Kimberly; Chen, Aimin 2020. Organophosphate esters in a cohort of pregnant women: Variability and predictors of exposure. Environmental research, 184 , 109255Ryder, Justin R; Xu, Peixin; Inge, Thomas H; Xie, Changchun; Jenkins, Todd M; Hur, Chin; Lee, Minyi; Choi, Jin; Michalsky, Marc P; Kelly, Aaron S; Urbina, Elaine M 2020. Thirty-Year Risk of Cardiovascular Disease Events in Adolescents with Severe Obesity. Obesity (Silver Spring, Md.), 28 3, 616-623Vuong, Ann M; Xie, Changchun; Jandarov, Roman; Dietrich, Kim N; Zhang, Hongmei; Sjödin, Andreas; Calafat, Antonia M; Lanphear, Bruce P; McCandless, Lawrence; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin 2020. Prenatal exposure to a mixture of persistent organic pollutants (POPs) and child reading skills at school age. International journal of hygiene and environmental health, 228 , 113527Yang, Weili; Vuong, Ann M; Xie, Changchun; Dietrich, Kim N; Karagas, Margaret R; Lanphear, Bruce P; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin 2020. Maternal cadmium exposure and neurobehavior in children: The HOME study. Environmental research, 186 , 109583Abdel Karim, Nagla Fawzy; Hassan, Rammey; Siddiqi, Nabeela Iffat; Eldessouki, Ihab; Gaber, Ola; Rahouma, Mohamed; Kamel, Mohamed; Yellu, Mhender; Gulati, Shuchi; Xie, Changchun; Magdy, Mohamed; Pruemer, Jane 2019. Impact of tricyclic antidepressants, selective serotonin reuptake inhibitors, and other antidepressants on overall survival of patients with advanced lung cancer from 2004 to 2014: University of Cincinnati experience. The Journal of international medical research, 47 12, 6016-6026Benoit, Justin L; McMullan, Jason T; Wang, Henry E; Xie, Changchun; Xu, Peixin; Hart, Kimberly W; Stolz, Uwe; Lindsell, Christopher J 2019. Timing of Advanced Airway Placement after Witnessed Out-of-Hospital Cardiac Arrest. Prehospital emergency care, 23 6, 838-846Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P 2019. Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 6, Fassler, Cecily S; Gutmark-Little, Iris; Xie, Changchun; Giannini, Courtney M; Chandler, Donald W; Biro, Frank M; Pinney, Susan M 2019. Sex Hormone Phenotypes in Young Girls and the Age at Pubertal Milestones. The Journal of clinical endocrinology and metabolism, 104 12, 6079-6089Fassler, Cecily S; Pinney, Sara E; Xie, Changchun; Biro, Frank M; Pinney, Susan M 2019. Complex relationships between perfluorooctanoate, body mass index, insulin resistance and serum lipids in young girls. Environmental research, 176 , 108558Greene, Alexis D; Kendziorski, Jessica A; Buckholz, Jeanette M; Niu, Liang; Xie, Changchun; Pinney, Susan M; Burns, Katherine A 2019. Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. Reproductive toxicology (Elmsford, N.Y.), 84 , 26-31Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A 2019. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine, 380 22, 2136-2145Kharofa, Jordan; Mierzwa, Michelle; Olowokure, Olugbenga; Sussman, Jeffrey; Latif, Tahir; Gupta, Anumeha; Xie, Changchun; Patel, Sameer; Esslinger, Hope; Mcgill, Brian; Wolf, Eric; Ahmad, Syed A 2019. Pattern of Marginal Local Failure in a Phase II Trial of Neoadjuvant Chemotherapy and Stereotactic Body Radiation Therapy for Resectable and Borderline Resectable Pancreas Cancer. American journal of clinical oncology, 42 3, 247-252Liang, Hong; Vuong, Ann M; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Yuan, Wei; Miao, Maohua; Braun, Joseph M; Dietrich, Kim N; Yolton, Kimberly; Lanphear, Bruce P; Chen, Aimin 2019. Childhood polybrominated diphenyl ether (PBDE) serum concentration and reading ability at ages 5 and 8 years: The HOME Study. Environment international, 122 , 330-339Vuong, Ann M; Braun, Joseph M; Wang, Zhiyang; Yolton, Kimberly; Xie, Changchun; Sjodin, Andreas; Webster, Glenys M; Lanphear, Bruce P; Chen, Aimin 2019. Exposure to polybrominated diphenyl ethers (PBDEs) during childhood and adiposity measures at age 8 years. Environment international, 123 , 148-155Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Dietrich, Kim N; Braun, Joseph M; Webster, Glenys M; Calafat, Antonia M; Lanphear, Bruce P; Chen, Aimin 2019. Prenatal and childhood exposure to poly- and perfluoroalkyl substances (PFAS) and cognitive development in children at age 8 years. Environmental research, 172 , 242-248Xie, Changchun; Leung, Yuet-Kin; Chen, Aimin; Long, Ding-Xin; Hoyo, Catherine; Ho, Shuk-Mei 2019. Differential methylation values in differential methylation analysis. Bioinformatics (Oxford, England), 35 7, 1094-1097DeFoor, W Robert; Inge, Thomas H; Jenkins, Todd M; Jackson, Elizabeth; Courcoulas, Anita; Michalsky, Marc; Brandt, Mary; Kollar, Linda; Xie, Changchun 2018. Prospective evaluation of urinary incontinence in severely obese adolescents presenting for weight loss surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 14 2, 214-218Karim, Nagla Abdel; Schuster, James; Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Xie, Changchun; Morris, John C 2018. Pulmonary sarcomatoid carcinoma: University of Cincinnati experience. Oncotarget, 9 3, 4102-4108Kim, Stephani; Xu, Xijin; Zhang, Yuling; Zheng, Xiangbin; Liu, Rongju; Dietrich, Kim; Reponen, Tiina; Ho, Shuk-Mei; Xie, Changchun; Sucharew, Heidi; Huo, Xia; Chen, Aimin 2018. Metal concentrations in pregnant women and neonates from informal electronic waste recycling. Journal of exposure science & environmental epidemiology, , Leung, Yuet-Kin; Ouyang, Bin; Niu, Liang; Xie, Changchun; Ying, Jun; Medvedovic, Mario; Chen, Aimin; Weihe, Pal; Valvi, Damaskini; Grandjean, Philippe; Ho, Shuk-Mei 2018. Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics, 13 3, 290-300Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M 2018. Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics, 141 2, Vuong, Ann M; Braun, Joseph M; Yolton, Kimberly; Wang, Zhiyang; Xie, Changchun; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2018. Prenatal and childhood exposure to perfluoroalkyl substances (PFAS) and measures of attention, impulse control, and visual spatial abilities. Environment international, 119 , 413-420Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2018. Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study. International journal of hygiene and environmental health, 221 1, 87-94Vuong, Ann M; Yolton, Kimberly; Wang, Zhiyang; Xie, Changchun; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2018. Childhood perfluoroalkyl substance exposure and executive function in children at 8?years. Environment international, 119 , 212-219Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin 2018. Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8years. Environment international, 111 , 224-231Gautam, Yadu; Altaye, Mekibib; Xie, Changchun; Mersha, Tesfaye B 2017. AdmixPower: Statistical Power and Sample Size Estimation for Mapping Genetic Loci in Admixed Populations. Genetics, 207 3, 873-882Herrick, Robert L; Buckholz, Jeanette; Biro, Frank M; Calafat, Antonia M; Ye, Xiaoyun; Xie, Changchun; Pinney, Susan M 2017. Polyfluoroalkyl substance exposure in the Mid-Ohio River Valley, 1991-2012. Environmental pollution (Barking, Essex : 1987), 228 , 50-60Martin, Andrew T; Pinney, Susan M; Xie, Changchun; Herrick, Robert L; Bai, Yun; Buckholz, Jeanette; Martin, Vincent T 2017. Headache Disorders May Be a Risk Factor for the Development of New Onset Hypothyroidism. Headache, 57 1, 21-30Owusu, Daniel; Pan, Yue; Xie, Changchun; Harirforoosh, Sam; Wang, Ke-Sheng 2017. Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. Journal of psychiatric research, 84 , 27-34Vuong, Ann M; Braun, Joseph M; Yolton, Kimberly; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2017. Prenatal and postnatal polybrominated diphenyl ether exposure and visual spatial abilities in children. Environmental research, 153 , 83-92Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2017. Prenatal and postnatal polybrominated diphenyl ether (PBDE) exposure and measures of inattention and impulsivity in children. Neurotoxicology and teratology, 64 , 20-28Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin 2017. Childhood polybrominated diphenyl ether (PBDE) exposure and neurobehavior in children at 8 years. Environmental research, 158 , 677-684Wang, Ke-Sheng; Liu, Xuefeng; Ategbole, Muyiwa; Xie, Xin; Liu, Ying; Xu, Chun; Xie, Changchun; Sha, Zhanxin 2017. Generalized Linear Mixed Model Analysis of Urban-Rural Differences in Social and Behavioral Factors for Colorectal Cancer Screening Asian Pacific journal of cancer prevention : APJCP, 18 9, 2581-2589Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Sjödin, Andreas; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin 2017. Erratum: "Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children". Environmental health perspectives, 125 6, 069001Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Sjödin, Andreas; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin 2017. Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children. Environmental health perspectives, 125 4, 746-752Agarwal, Rishi; Sendilnathan, Arun; Siddiqi, Nabeela Iffat; Gulati, Shuchi; Ghose, Abhimanyu; Xie, Changchun; Olowokure, Olugbenga Olanrele 2016. Advanced biliary tract cancer: clinical outcomes with ABC-02 regimen and analysis of prognostic factors in a tertiary care center in the United States. Journal of gastrointestinal oncology, 7 6, 996-1003Agarwal, Sunil; Mark, Jonathan; Xie, Changchun; Ghulam, Enas; Patil, Yash 2016. Survival and Prognosis for Malignant Tumors of Odontogenic Origin. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 155 1, 113-6Lindsley, Andrew W; Saal, Howard M; Burrow, Thomas A; Hopkin, Robert J; Shchelochkov, Oleg; Khandelwal, Pooja; Xie, Changchun; Bleesing, Jack; Filipovich, Lisa; Risma, Kimberly; Assa'ad, Amal H; Roehrs, Phillip A; Bernstein, Jonathan A 2016. Defects of B-cell terminal differentiation in patients with type-1 Kabuki syndrome. The Journal of allergy and clinical immunology, 137 1, 179-187.e10Wang, Ke-Sheng; Liu, Xuefeng; Xie, Changchun; Liu, Ying; Xu, Chun 2016. Non-parametric Survival Analysis of EPG5 Gene with Age at Onset of Alzheimer's Disease. Journal of molecular neuroscience : MN, 60 4, 436-444Wang, Ke-Sheng; Owusu, Daniel; Pan, Yue; Xie, Changchun 2016. Bayesian logistic regression in detection of gene-steroid interaction for cancer at PDLIM5 locus. Journal of genetics, 95 2, 331-40Chen, Aimin; Xu, Fan; Xie, Changchun; Wu, Tianying; Vuong, Ann M; Miao, Maohua; Yuan, Wei; DeFranco, Emily A 2015. Gestational Weight Gain Trend and Population Attributable Risks of Adverse Fetal Growth Outcomes in Ohio. Paediatric and perinatal epidemiology, 29 4, 346-50Li, Yue; Xie, Changchun; Murphy, Susan K; Skaar, David; Nye, Monica; Vidal, Adriana C; Cecil, Kim M; Dietrich, Kim N; Puga, Alvaro; Jirtle, Randy L; Hoyo, Cathrine 2015. Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environmental health perspectives, , Wang, Ke-Sheng; Zuo, Lingjun; Pan, Yue; Xie, Changchun; Luo, Xingguang 2015. Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations. Journal of psychiatric research, 71 , 1-7Xie, Changchun 2015. Resveratrol does not reduce CVD risk, prolong life - A statistical point of view. Contemporary clinical trials communications, 1 , 1Bailey, Swneke D; Xie, Changchun; Paré, Guillaume; Montpetit, Alexandre; Mohan, Viswanathan; Yusuf, Salim; Gerstein, Hertzel; Engert, James C; Anand, Sonia S 2014. Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI. Diabetologia, 57 4, 738-45Chen, Yaolong; Yang, Kehu; Jing, Tao; Tian, Jinhui; Shen, Xiping; Xie, Changchun; Ma, Bin; Liu, Yali; Yao, Liang; Cao, Xiaoyuan 2014. Use of text messages to communicate clinical recommendations to health workers in rural China: a cluster-randomized trial. Bulletin of the World Health Organization, 92 7, 474-81Tang, Zhe; Zhou, Tao; Luo, Yanxia; Xie, Changchun; Huo, Da; Tao, Lixin; Pan, Lei; Sun, Fei; Zhu, Huiping; Yang, Xinghua; Wang, Wei; Yan, Aoshuang; Li, Xia; Guo, Xiuhua 2014. Risk factors for cerebrovascular disease mortality among the elderly in Beijing: a competing risk analysis. PloS one, 9 2, e87884Xie, Changchun 2014. Relations among Three Parametric Multiple Testing Methods for Correlated Tests. Journal of statistical computation and simulation, 84 4, 812-818Zhou, Tao; Li, Xia; Tang, Zhe; Xie, Changchun; Tao, Lixin; Pan, Lei; Huo, Da; Sun, Fei; Luo, Yanxia; Wang, Wei; Yan, Aoshuang; Guo, Xiuhua 2014. Risk factors of CVD mortality among the elderly in Beijing, 1992 - 2009: an 18-year cohort study. International journal of environmental research and public health, 11 2, 2193-208Anand, Sonia S; Meyre, David; Pare, Guillaume; Bailey, Swneke D; Xie, Changchun; Zhang, Xiaohe; Montpetit, Alexandre; Desai, Dipika; Bosch, Jackie; Mohan, Viswanathan; Diaz, Rafael; McQueen, Matthew J; Cordell, Heather J; Keavney, Bernard; Yusuf, Salim; Gaudet, Daniel; Gerstein, Hertzel; Engert, James C 2013. Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study. Diabetes care, 36 9, 2836-42Kirsh, Elliana R; van Leer, Eva; Phero, Heidi J; Xie, Changchun; Khosla, Sid 2013. Factors associated with singers' perceptions of choral singing well-being. Journal of voice : official journal of the Voice Foundation, 27 6, 786.e25-32Xie, Changchun; Chen, Ding-Geng 2013. Letter to the editor. Biometrical journal. Biometrische Zeitschrift, 55 2, 264-5Yamanaka, Osamu; Yuan, Yong; Coulson-Thomas, Vivien Jane; Gesteira, Tarsis Ferreira; Call, Mindy K; Zhang, Yujin; Zhang, Jianhua; Chang, Shao-Hsuan; Xie, Changchun; Liu, Chia-Yang; Saika, Shizuya; Jester, James V; Kao, Winston W-Y 2013. Lumican binds ALK5 to promote epithelium wound healing. PloS one, 8 12, e82730Chen, Yao-Long; Yao, Liang; Xiao, Xiao-Juan; Wang, Qi; Wang, Ze-Hao; Liang, Fu-Xiang; Liang, Hui; Wang, Xin; Shen, Xi-Ping; Xie, Chang-Chun; Yang, Ke-Hu 2012. Quality assessment of clinical guidelines in China: 1993 - 2010. Chinese medical journal, 125 20, 3660-4Xie, Changchun 2012. Weighted multiple testing correction for correlated tests. Statistics in medicine, 31 4, 341-52Zbuk, Kevin; Xie, Changchun; Young, Robin; Heydarpour, Mahyar; Pare, Guillaume; Davis, A Darlene; Miller, Ruby; Lanktree, Matthew B; Saleheen, Danish; Danesh, John; Yusuf, Salim; Engert, James C; Hegele, Robert A; Anand, Sonia S 2012. BRCA2 variants and cardiovascular disease in a multi-ethnic study. BMC medical genetics, 13 , 56Chow, Clara K; Islam, Shofiqul; Bautista, Leonelo; Rumboldt, Zvonko; Yusufali, Afzal; Xie, Changchun; Anand, Sonia S; Engert, James C; Rangarajan, Sumathy; Yusuf, Salim 2011. Parental history and myocardial infarction risk across the world: the INTERHEART Study. Journal of the American College of Cardiology, 57 5, 619-27Do, Ron; Xie, Changchun; Zhang, Xiaohe; Männistö, Satu; Harald, Kennet; Islam, Shofiqul; Bailey, Swneke D; Rangarajan, Sumathy; McQueen, Matthew J; Diaz, Rafael; Lisheng, Liu; Wang, Xingyu; Silander, Kaisa; Peltonen, Leena; Yusuf, Salim; Salomaa, Veikko; Engert, James C; Anand, Sonia S 2011. The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study. PLoS medicine, 8 10, e1001106Mercuri, Mathew; Mehta, Shamir; Xie, Changchun; Valettas, Nicholas; Velianou, James L; Natarajan, Madhu K 2011. Radial artery access as a predictor of increased radiation exposure during a diagnostic cardiac catheterization procedure. JACC. 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Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology, 56 19, 1552-63Bailey, Swneke D; Xie, Changchun; Do, Ron; Montpetit, Alexandre; Diaz, Rafael; Mohan, Viswanathan; Keavney, Bernard; Yusuf, Salim; Gerstein, Hertzel C; Engert, James C; Anand, Sonia 2010. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. 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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nature genetics, 41 3, 334-41Anand, Sonia S; Xie, Changchun; Paré, Guillaume; Montpetit, Alexandre; Rangarajan, Sumathy; McQueen, Matthew J; Cordell, Heather J; Keavney, Bernard; Yusuf, Salim; Hudson, Thomas J; Engert, James C 2009. Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study. Circulation. Cardiovascular genetics, 2 1, 16-25Mercuri, Mat; Natarajan, Madhu K; Holder, Douglas H; Xie, Changchun; Gafni, Amiram 2009. Insight into capacity planning for cardiac catheterization services: policy lessons learned from "Looking in the Mirror" over a decade. Health policy (Amsterdam, Netherlands), 91 3, 314-20Mercuri, Mathew; Xie, Changchun; Levy, Michael; Valettas, Nicholas; Natarajan, Madhu K 2009. Predictors of increased radiation dose during percutaneous coronary intervention. The American journal of cardiology, 104 9, 1241-4de Koning, Lawrence; Merchant, Anwar T; Hegele, Robert A; Xie, Changchun; Vuksan, Vlad; Teo, Koon; Yusuf, Salim; Anand, Sonia S 2008. Association of the FABP2 T54 variant with plasma triglycerides and insulin resistance in a multiethnic population. Clinical chemistry, 54 10, 1742-4Xavier, Denis; Pais, Prem; Devereaux, P J; Xie, Changchun; Prabhakaran, D; Reddy, K Srinath; Gupta, Rajeev; Joshi, Prashant; Kerkar, Prafulla; Thanikachalam, S; Haridas, K K; Jaison, T M; Naik, Sudhir; Maity, A K; Yusuf, Salim 2008. Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data. Lancet, 371 9622, 1435-42, ; Anand, Sonia; Yusuf, Salim; Xie, Changchun; Pogue, Janice; Eikelboom, John; Budaj, Andrzej; Sussex, Bruce; Liu, Lisheng; Guzman, Randy; Cina, Claudio; Crowell, Richard; Keltai, Matyas; Gosselin, Gilbert 2007. Oral anticoagulant and antiplatelet therapy and peripheral arterial disease. The New England journal of medicine, 357 3, 217-27Eikelboom, John W; Mehta, Shamir R; Anand, Sonia S; Xie, Changchun; Fox, Keith A A; Yusuf, Salim 2006. Adverse impact of bleeding on prognosis in patients with acute coronary syndromes. Circulation, 114 8, 774-82Schwalm, Jon-David Reid; Ahmad, Mayraj; Velianou, James L; Xie, Changchun; Natarajan, Madhu K 2006. Primary and rescue percutaneous coronary intervention with paclitaxel-eluting stent implantation in ST-elevation myocardial infarction. The American journal of cardiology, 97 9, 1308-10Mehta, Shamir R; Yusuf, Salim; Díaz, Rafael; Zhu, Jun; Pais, Prem; Xavier, Denis; Paolasso, Ernesto; Ahmed, Rashid; Xie, Changchun; Kazmi, Khawar; Tai, Javed; Orlandini, Andrés; Pogue, Janice; Liu, Lisheng 2005. Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. JAMA, 293 4, 437-46Yusuf, Salim; Mehta, Shamir R; Xie, Changchun; Ahmed, Rashid J; Xavier, Denis; Pais, Prem; Zhu, Jun; Liu, Lisheng 2005. Effects of reviparin, a low-molecular-weight heparin, on mortality, reinfarction, and strokes in patients with acute myocardial infarction presenting with ST-segment elevation. JAMA, 293 4, 427-35Yusuf, Salim; Mehta, Shamir R; Díaz, Rafael; Paolasso, Ernesto; Pais, Prem; Xavier, Denis; Xie, Changchun; Ahmed, Rashid J; Khazmi, Khawar; Zhu, Jun; Liu, Lisheng 2004. Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: the CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction. American heart journal, 148 6, 1068-78Anand, Sonia S; Davis, A Darlene; Ahmed, Rashid; Jacobs, Ruby; Xie, Changchun; Hill, Amber; Sowden, Joon; Atkinson, Stephanie; Blimkie, Cameron; Brouwers, Melissa; Morrison, Katherine; de Koning, Larry; Gerstein, Hertzel; Yusuf, Salim . A family-based intervention to promote healthy lifestyles in an aboriginal community in Canada. Canadian journal of public health = Revue canadienne de santé publique, 98 6, 447-52Natarajan, Madhu K; Strauss, Bradley H; Rokoss, Michael; Buller, Christopher E; Mancini, G B John; Xie, Changchun; Sheth, Tej N; Goodhart, David; Cohen, Eric A; Seidelin, Peter; Harper, William; Gerstein, Hertzel C . Randomized trial of insulin versus usual care in reducing restenosis after coronary intervention in patients with diabetes. the STent Restenosis And Metabolism (STREAM) study. Cardiovascular revascularization medicine : including molecular interventions, 13 2, 95-100Rebholz, Sandra L; Jones, Thomas; Herrick, Robert L; Xie, Changchun; Calafat, Antonia M; Pinney, Susan M; Woollett, Laura A . Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice. Toxicology reports, 3 , 46-54Wang, Kesheng; Xu, Chun; Theeke, Laurie A; Xiao, Danqing; Luo, Xingguang; Xie, Changchun . Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer's Disease. Nursing research, 72 1, 66-73
Research InterestsMy research interests include 1) clinical trials, 2) statistical genetics: next generation sequencing, Genome-wide association study, NDA methylation, gene environmental interaction, 3) statistical methodology: survival models, multiple testing, hierarchical generalized linear models, nonparametric methods, longitudinal data and multivariate statistical analysis.
Peer Reviewed Publications An, Yu; Fnu, Gulimirerouzi; Xie, Changchun; Weber, Georg F 2023. Meta-analysis of Osteopontin splice variants in cancer. BMC cancer, 23 1, 373Connelly, Katherine M; Winslow, Stephanie E; Smith, Justin; Ahmad, Saad S; Xie, Changchun; Hinckley, William R; Gottula, Adam L; Lane, Bennett H 2023. Management of patients with impella devices or intra-aortic balloon pumps during helicopter air ambulance transport in observational data. Perfusion, , 2676591231158273Lewis, Clayton S; Bari, Khurram; Xie, Changchun; Sherman, Kenneth E; Vasse, Marc; Van Dreden, Patrick; Bogdanov, Vladimir Y 2023. Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease. BMC gastroenterology, 23 1, 65Wang, Kesheng; Shafique, Saima; Xiao, Danqing; Walter, Suzy Mascaro; Liu, Ying; Piamjariyakul, Ubolrat; Xie, Changchun 2023. Repeated measures analysis of opioid use disorder treatment on clinical opiate withdrawal scale in a randomized clinical trial: sex differences. Journal of addictive diseases, , 1-12Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2023. Gestational exposure to organophosphate esters and infant anthropometric measures in the first 4 weeks after birth. The Science of the total environment, 857 Pt 1, 159322Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2023. Associations of gestational exposure to organophosphate esters with gestational age and neonatal anthropometric measures: The HOME study. Environmental pollution (Barking, Essex : 1987), 316 Pt 1, 120516Wang, Kesheng; DiChiacchio, Toni; Fang, Wei; Lander, Laura; Feinberg, Judith; Xie, Changchun; Winstanley, Erin L; Ubolrat Piamjariyakul, 2022. Longitudinal study of impact of medication for opioid use disorder on Hamilton Depression Rating Scale. Journal of affective disorders, 297 , 148-155Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Werner, Erika; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2022. Maternal urinary OPE metabolite concentrations and blood pressure during pregnancy: The HOME study. Environmental research, 207 , 112220Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin 2022. Maternal urinary organophosphate ester metabolite concentrations and glucose tolerance during pregnancy: The HOME Study. International journal of hygiene and environmental health, 245 , 114026Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M 2021. Air pollution and the pandemic: Long-term PM2.5 exposure and disease severity in COVID-19 patients. Respirology (Carlton, Vic.), 26 12, 1181-1187Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M 2021. Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients. Respiratory medicine, 178 , 106313Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Hoofnagle, Andy; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Yolton, Kimberly; Chen, Aimin 2021. Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones. American journal of epidemiology, 190 9, 1793-1802Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Chen, Aimin; Yolton, Kimberly 2021. Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study. Neurotoxicology, 87 , 149-155Ryder, Justin R; Xu, Peixin; Nadeau, Kristen J; Kelsey, Megan M; Xie, Changchun; Jenkins, Todd; Inge, Thomas H; Bjornstad, Petter 2021. Effect of surgical versus medical therapy on estimated cardiovascular event risk among adolescents with type 2 diabetes and severe obesity. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 17 1, 23-33Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Dietrich, Kim N; Braun, Joseph M; Webster, Glenys M; Calafat, Antonia M; Lanphear, Bruce P; Chen, Aimin 2021. Childhood exposure to per- and polyfluoroalkyl substances (PFAS) and neurobehavioral domains in children at age 8 years. Neurotoxicology and teratology, 88 , 107022Wang, Kesheng; Xu, Chun; Smith, Amanda; Xiao, Danqing; Navia, R Osvaldo; Lu, Yongke; Xie, Changchun; Piamjariyakul, Ubolrat 2021. Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Progress in neuro-psychopharmacology & biological psychiatry, 111 , 110393Xu, Zongli; Xie, Changchun; Taylor, Jack A; Niu, Liang 2021. ipDMR: identification of differentially methylated regions with interval P-values. Bioinformatics (Oxford, England), 37 5, 711-713Abdel Karim, Nagla; Khaddasn, Sinan; Shehata, Mahmoud; Mostafa, Ahmed; Magdy, Mohamed; Eldessouki, Ihab; Xie, Changchun; Benzequene, Sadia 2020. Stenting in Non-Small Cell Lung Cancer: How Does It Affect the Outcomes? Asian Pacific journal of cancer prevention : APJCP, 21 1, 175-178Bjornstad, Petter; Hughan, Kara; Kelsey, Megan M; Shah, Amy S; Lynch, Jane; Nehus, Edward; Mitsnefes, Mark; Jenkins, Todd; Xu, Peixin; Xie, Changchun; Inge, Thomas; Nadeau, Kristen 2020. Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes. Diabetes care, 43 1, 187-195Derderian, S Christopher; Dewberry, Lindel C; Patten, Luke; Sitzman, Thomas J; Kaizer, Alexander M; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Mitchell, James E; Inge, Thomas 2020. Excess skin problems among adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 8, 993-998Derderian, S Christopher; Patten, Luke; Kaizer, Alexander M; Inge, Thomas H; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Dewberry, Lindel C; Sitzman, Thomas J 2020. Body contouring in adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 1, 137-142Kim, Stephani S; Xu, Xijin; Zhang, Yuling; Zheng, Xiangbin; Liu, Rongju; Dietrich, Kim N; Reponen, Tiina; Xie, Changchun; Sucharew, Heidi; Huo, Xia; Chen, Aimin 2020. Birth outcomes associated with maternal exposure to metals from informal electronic waste recycling in Guiyu, China. Environment international, 137 , 105580Percy, Zana; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Lanphear, Bruce P; Yolton, Kimberly; Vuong, Ann M; Cecil, Kim M; Braun, Joseph M; Xie, Changchun; Chen, Aimin 2020. Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out. Chemosphere, 239 , 124701Percy, Zana; Vuong, Ann M; Ospina, Maria; Calafat, Antonia M; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Xie, Changchun; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Yolton, Kimberly; Chen, Aimin 2020. Organophosphate esters in a cohort of pregnant women: Variability and predictors of exposure. Environmental research, 184 , 109255Ryder, Justin R; Xu, Peixin; Inge, Thomas H; Xie, Changchun; Jenkins, Todd M; Hur, Chin; Lee, Minyi; Choi, Jin; Michalsky, Marc P; Kelly, Aaron S; Urbina, Elaine M 2020. Thirty-Year Risk of Cardiovascular Disease Events in Adolescents with Severe Obesity. Obesity (Silver Spring, Md.), 28 3, 616-623Vuong, Ann M; Xie, Changchun; Jandarov, Roman; Dietrich, Kim N; Zhang, Hongmei; Sjödin, Andreas; Calafat, Antonia M; Lanphear, Bruce P; McCandless, Lawrence; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin 2020. Prenatal exposure to a mixture of persistent organic pollutants (POPs) and child reading skills at school age. International journal of hygiene and environmental health, 228 , 113527Yang, Weili; Vuong, Ann M; Xie, Changchun; Dietrich, Kim N; Karagas, Margaret R; Lanphear, Bruce P; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin 2020. Maternal cadmium exposure and neurobehavior in children: The HOME study. Environmental research, 186 , 109583Abdel Karim, Nagla Fawzy; Hassan, Rammey; Siddiqi, Nabeela Iffat; Eldessouki, Ihab; Gaber, Ola; Rahouma, Mohamed; Kamel, Mohamed; Yellu, Mhender; Gulati, Shuchi; Xie, Changchun; Magdy, Mohamed; Pruemer, Jane 2019. Impact of tricyclic antidepressants, selective serotonin reuptake inhibitors, and other antidepressants on overall survival of patients with advanced lung cancer from 2004 to 2014: University of Cincinnati experience. The Journal of international medical research, 47 12, 6016-6026Benoit, Justin L; McMullan, Jason T; Wang, Henry E; Xie, Changchun; Xu, Peixin; Hart, Kimberly W; Stolz, Uwe; Lindsell, Christopher J 2019. Timing of Advanced Airway Placement after Witnessed Out-of-Hospital Cardiac Arrest. Prehospital emergency care, 23 6, 838-846Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P 2019. Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 6, Fassler, Cecily S; Gutmark-Little, Iris; Xie, Changchun; Giannini, Courtney M; Chandler, Donald W; Biro, Frank M; Pinney, Susan M 2019. Sex Hormone Phenotypes in Young Girls and the Age at Pubertal Milestones. The Journal of clinical endocrinology and metabolism, 104 12, 6079-6089Fassler, Cecily S; Pinney, Sara E; Xie, Changchun; Biro, Frank M; Pinney, Susan M 2019. Complex relationships between perfluorooctanoate, body mass index, insulin resistance and serum lipids in young girls. Environmental research, 176 , 108558Greene, Alexis D; Kendziorski, Jessica A; Buckholz, Jeanette M; Niu, Liang; Xie, Changchun; Pinney, Susan M; Burns, Katherine A 2019. Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 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