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Medical Scientist Training Program

MSTP Faculty

Looking for faculty who share your research interests? Check out our new Research Directory.

Name Research Bio Contact
Alenghat, Theresa Epithelial and immune cell homeostasis in the context of intestinal health and disease. The goals of the lab are to provide insight into molecular mechanisms, including epigenomic pathways, that mediate the host-microbiota relationship. Theresa.Alenghat@cchmc.org

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Askew, David Understand the contribution of endoplasmic reticulum stress responses to the virulence and antifungal drug susceptibility of the pathogenic mold Aspergillus fumigatus. askewds@ucmail.uc.edu

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Baccei, Mark Neurobiological mechanisms underlying pediatric pain; Maturation of nociceptive circuits in the CNS under normal and pathological conditions.

mark.baccei@uc.edu

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Barski, Artem Epigenomics with a focus on the mechanisms of epigenetic regulation involved in T helper cell activation, tolerance and memory. User-friendly bioinformatics for epigenomics and NGS data in general.  

artem.barski@cchmc.org

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Bezerra, Jorge Investigation of the developmental basis of pediatric liver disease, with a focus genetic, cellular and molecular circuitsthat control injury and survival signals. jorge.bezerra@cchmc.org

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Blackard, Jason

Currently directs a translational research laboratory which focuses on human and mechanistic studies to understand the interactions between various viral pathogens. Using a variety of cell culture systems, molecular virology techniques, and patient-derived samples, I investigate the pathogenic and evolutionary mechanisms by which viruses interact with the host and cause disease. At present, laboratory studies involve hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus (HEV), pegiviruses (HPgV; GBV-C), and HIV and include international collaborations in South Africa, Botswana, India, Nigeria, and Ghana.

blackajt@ucmail.uc.edu

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Bogdanov, Vladimir Biochemistry of Blood Coagulation, Expression and Alternative Splicing of Tissue Factor (TF) pre-mRNA in the Vasculature, Circulating TF in Health and Disease, TF and the Pathobiology of Cancer, Alternatively Spliced TF and Angiogenesis. bogdanvr@ucmail.uc.edu

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Boissy, Raymond Molecular biology of the melanocyte; pathophysiology of pigment disorders. boissyre@ucmail.uc.edu

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Boscolo, Elisa Translational and molecular studies to identify new therapeutic targeted drugs for developmental vascular anomalies. elisa.boscolo@cchmc.org

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Brugmann, Samantha Interested in craniofacial development and the etiology of craniofacial disorders. samantha.brugmann@cchmc.org

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Campbell, Kenneth Our research focuses on the molecular genetics of neural development with a focus on development of the basal ganglia and surrounding ventral telencephalic regions. kenneth.campbell@cchmc.org

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Cancelas Perez, Jose Cellular and molecular mechanisms of normal and cancer hematopoietic stem cells, and transfusion medicine. jose.cancelas@uc.edu

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Cecil, Kim Our research employs magnetic resonance spectroscopy and imaging techniques to evaluate the effects of environmental neurotoxicants on humans. We also study neurological disorders such as creatine deficiency syndromes. kim.cecil@cchmc.org

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Chen, Aimin Environmental chemical exposure and adverse impact on birth outcomes and child neurobehavioral development; perinatal and pediatric environmental epidemiology. chenai@ucmail.uc.edu Website
Chougnet, Claire

HIV/AIDS pathogenesis; ontogeny of the immune system; immune dysfunction in aging; human immunology.

claire.chougnet@cchmc.org

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Clark, Joseph Concussion and mTBI diagnosis, management, return to play, rehabilitation and recovery. clarkjf@ucmail.uc.edu

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Cleveland, Zackary Our research focuses on developing radiation-fee methods to quantify regional lung structure and function in patients and small animal models of disease. Specifically, we apply ultra-short echo time and hyperpolarized gas MRI to a variety of disorders, including environmental exposure, interstitial lung disease, cystic fibrosis, and acute lung injury.

Zackary.Cleveland@cchmc.org

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Crone, Steven Neural control of breathing. We develop therapies to alter activity of respiratory neurons to improve ventilation in mouse models (and patients) with neuromuscular disease or spinal cord injury.

Steven.Crone@cchmc.org

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Cushion, Melanie

Metatranscriptomics and preclinical drug development for treatment of the AIDS-related opportunistic pathogen Pneumocystis carinii.

cushiomt@ucmail.uc.edu

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Czyzyk-Krzeska, Maria Molecular pathways regulated by renal cancer tumor suppressor, particularly VHL. Mechanisms of oncogenic and tumorsuppressing autophagy. MicroRNA networks in control of autophagy. czyzkm@ucmail.uc.edu

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Danzer, Steve Our lab focuses on elucidating the basic mechanisms that underlie the development of temporal lobe epilepsy. We also investigate the mechanisms that regulate the development of epilepsy comorbidities, such as stress-anxiety disorders and depression.  

steve.danzer@cchmc.org

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Davidson, Sean The overall aim of the lab is to understand the mechanisms by which the body protects itself from heart disease. We use mutagenesis and spectroscopic techniques to study the structure/function relationships of the proteins that comprise high density lipoproteins.
davidswm@ucmail.uc.edu

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Davidson, Steve Neurobiology of chronic pain. Dissection of supraspinal circuits regulating pain using optogenetics/chemogenetics in animal models. Recovery of human peripheral neurons for neurophysiological studies of non-opioid analgesics.  

steve.davidson@uc.edu

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Deepe, George We examine the host response to fungal pathogens, in particular Histoplasma capsulatum. Our principal goals are tounderstand the immune regulators of resistance and susceptiblity. deepegs@ucmail.uc.edu

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DeMazumder, Deeptankar  Physician-scientist in cardiac electrophysiology (EP) focusing on the mechanistic link between heart failure and sudden cardiac death in the context of patho/physiological mechanisms, novel therapies, clinically-relevant animal models, “big data” predictive analytics and epidemiology.
deeptankar.demazumder@uc.edu

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Deka, Ranjan Epidemiology and genetics of complex diseases, particularly identifying susceptibility genes predisposing individuals to cardiometabolic diseases and type 2 diabetes. dekar@ucmail.uc.edu

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DelBello, Melissa Neurodevelopment of childhood and adolescent bipolar and the neuropsychopharmacology of bipolar disorder inchildren and adolescents.

melissa.delbello@uc.edu

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Deshmukh, Hitesh

Using a combination of human studies and developmentally appropriate preclinical models in non-human primates and mice, our lab investigates the cellular components and molecular targets by which intestinal commensal bacteria direct development of innate defenses of the lungs in newborns.  

Hitesh.Deshmukh@cchmc.org

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Dexheimer, Judith Studies developing, implementing and evaluating clinical information systems, including clinical decision and artificial intelligence applications. Her research focuses on the design, implementation and evaluation of clinical decision support systems improving clinical care.

Judith.Dexheimer@cchmc.org

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Dey, Sudhansu Molecular and genetic basis of embryo implantation. sk.dey@cchmc.org

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Divanovic, Senad Innate immune responses; obesity; NAFLD; preterm birth. senad.divanovic@cchmc.org

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Erickson, Craig Fragile X syndrome; autism spectrum disorders. Craig.Erickson@cchmc.org

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Gebelein, Brian Patterning the nervous system during development. brian.gebelein@cchmc.org

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Grimes, H. Leighton  Mechanistic and pre-translational studies of hematopoietic disorders, including marrow failure, myelodysplasia and leukemia. lee.grimes@cchmc.org

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Gross, Nina Analysis of molecular mechanisms underlying brain disorders such as Fragile X syndrome, epilepsy and autism with the goal to identify novel treatment targets. Christina.Gross@cchmc.org

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Guan, Jun-Lin

The overall goals of the Guan laboratory is to understand the fundamental principles of cell signaling in the regulation of basic cellular functions in normal cell and developmental processes and to determine how the disruption of normal signaling pathways lead to diseases such as cancer.

guanjl@ucmail.uc.edu

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Hamada, Fumika Thermo- and pain sensation in Drosophila. Fumika.Hamada@cchmc.org

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Harley, John Lupus genetics, genetics, and genomics. john.harley@cchmc.org

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Hassett, Daniel We work on CF lung disease. We patented a novel treatment that has been through animal toxicology and human phase I trials, acidified nitrite.

daniel.hassett@uc.edu

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Herman, James Structural, functional and molecular biological principles underlying brain stress integration. HERMANJS@UCMAIL.UC.EDU

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Herr, Andrew Biophysical and structural studies of proteins involved in bacterial biofilm formation, humoral immune responses, andthrombosis. andrew.herr@cchmc.org

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Hershey, Gurjit Khurana Focuses on delineating the genetic and environmental factors that promote asthma /allergy phenotypes and dissecting the mechanisms by which they confer risk, and significantlyadvancing the knowledge of the immunomodulatory roles of allergens and other exposures.
gurjit.hershey@cchmc.org

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Hildeman, David Molecular biology of antigen-specific T cells, including cell signaling, apoptosis, and development of memory. Noveltherapeutics to eliminate T cells causing autoimmunity and transplant rejection. david.hildeman@cchmc.org

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Ho, Chia-Chi Apply micro fabrication and nanotechnology to construct precisely designed geometrical networks of neuronal cluster and bottom up assembly of tissues. chiachi.ho@uc.edu

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Hogenesch, John Our lab studies genome and circadian biology in mammals. We focus on how we can leverage this knowledge to improve human health.  John.Hogenesch@cchmc.org

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Holland, Christy Diagnostic and therapeutic ultrasound and image-guided targeted drug delivery.

Christy.Holland@uc.edu

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Hong, Christian Roles of circadian rhythms in the gastrointestinal system, development of colorectal cancer and its treatment. christian.hong@uc.edu

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Huang, Taosheng Molecular basis of genetic syndromes, to apply the discoveries from rare diseases to common conditions, and to develop treatments for genetic diseases. taosheng.huang@cchmc.org

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Hui, David Influence of genetic factors such as apoE, LDL receptor family proteins, and pancreatic digestive enzymes, in modulating cardiometabolic diseases, including atherosclerosis, obesity, and diabetes. huidy@ucmail.uc.edu

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Hwa, Vivian Our lab is interested in studying patients with severe growth disorders in order to understand the molecular basis of growth and its perturbations. Vivian.Hwa@cchmc.org

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Jankowski, Michael Our lab is interested in the molecular mechanisms of sensory neuron plasticity after peripheral injuries in adults and neonates.

Michael.Jankowski@cchmc.org

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Jegga, Anil Design, develop and apply novel and robust computational approaches that will accelerate the diffusion of genomics into biomedical research and education and convert the genomics data deluge into systematized knowledge to enable translational research. Research focus areas: computational drug discovery and drug repositioning, network medicine, systems biology of disease and drug response

anil.jegga@cchmc.org

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Jiang, Rulang Mechanisms of craniofacial, kidney, and musculoskeletal organ development. rulang.jiang@cchmc.org

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Kalfa, Theodosia Erythropoiesis studies focused on signaling and cytoskeletal requirements in erythroblast cytokinesis and enucleation. Role of Rac GTPases and NADPH oxidase in generation of ROS from sickle cells and their role in SCD pathogenesis.

theodosia.kalfa@cchmc.org

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Kalin, Tanya Mechanisms of Interstitial lung diseases. Idiopathic Pulmonary Fibrosis. Transcriptional regulation of cancer progression and metastasis. Tumor microenvironment. Chemotherapeutic drug development. tatiana.kalin@cchmc.org

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Kalinichenko, Vladimir Transcriptional regulation of epithelial and endothelial cell functions during lung embryonic development and lung carcinogenesis; winged helix/forkhead box (Fox) proteins and their role in regulating cell signaling pathways required for cellular proliferation, differentiation, motility and survival; identify and increase understanding of currently unknown mechanisms that cause human lung malformations and promote lung cancer formation.

vladimir.kalinichenko@cchmc.org

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Kopan, Raphael Mechanism of notch signaling, its role in organogenesis, the impact of aging on stem cells and the chromatinregulation by transcription factors at the single cell level.

Raphael.Kopan@cchmc.org

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Kottyan, Leah

The Kottyan lab works to identify the molecular mechanisms mediating the genetic etiology of Systemic lupus erythematous and Eosinophilic Esophagitis.

leah.kottyan@cchmc.org

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Kovall, Rhett Transcription regulation in the Notch signaling pathway; aberrant Notch signaling underlying the pathogenesis of human diseases including congenital defects, cardiovascular disease, and cancer.

rhett.kovall@uc.edu

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Kranias, Litsa Elucidate the role of Ca-handling and Ca-signaling in myocardial function and survival with the aim to provide fundamental mechanistic insights and identify novel therapeutic modalities. litsa.kranias@uc.edu

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Kumar, Ashish We are studying the biology of infant leukemia to identify novel therapeutic approaches. ashish.kumar@cchmc.org

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Lang, Richard Non-visual opsins and light response pathways in development and homeostasis richard.lang@cchmc.org

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Le Cras, Tim Vascular Malformations & Disease in Children Tim.LeCras@cchmc.org

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Lu, Long (Jason) Unraveling the molecular mechanisms underlying human diseases using computational approaches. long.lu@cchmc.org

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Lu, Richard Q.  Molecular mechanisms of glial biology, neurological disorders, and brain cancers; Gene regulatory networks for functional regeneration in demyelinating diseases. Novel therapeutic approaches to brain tumors. Richard.Lu@cchmc.org

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Mackenzie, Bryan Iron homeostasis and disorders of iron metabolism. Molecular physiology and structure–function of human iron-transport proteins (DMT1, ferroportin, ZIP14). bryan.mackenzie@uc.edu

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Malik, Punam Research focus is gene therapy or gene editing of hematopoietic stem cells to correct hemoglobinopathies and other stem cell disorders, stem cell maintenance during genetic manipulation, non-toxic conditioning. Also, studies on pathophysiology of sickle cell disease, to reduce morbidity and mortality from sickle cell disease.  

punam.malik@cchmc.org

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Mast, Douglas T.  Therapeutic applications of medical ultrasound including image guidance and control of cancer ablation, biofeedback in speech therapy, ultrasound-enhanced drug delivery, and noninvasive measurements of tissue biomechanics.

doug.mast@uc.edu

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McCormack, Francis Particularly interested in the antimicrobial, antioxidant, and immunomodulatory roles of surfactant proteins A and D in the alveolar space. frank.mccormack@uc.edu

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Mersha,Tesfaye

Dr. Mersha’s research interests lie in combining quantitative, ancestry and statistical genomics to unravel genetic and non-genetic contributions to asthma and asthma-related allergic disorders in human populations.

tesfaye.mersha@cchmc.org

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Millay, Douglas We are interested the mechanisms that govern the development and regeneration of skeletal muscle. Our current focus is to understand the molecules and mechanisms that mediate myoblast fusion. Douglas.Millay@cchmc.org

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Miraldi, Emily  

Systems biology to immunoengineer, building mathematical models of the immune system from high-dimensional genomics measurements, to re-engineer immune responses in the context of autoimmune and other diseases. 

 

emily.miraldi@cchmc.org

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Molkentin, Jeffery Transcriptional control of cardiac development and the molecular signaling pathways involved in cardiac hypertrophy. jeff.molkentin@cchmc.org

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Nakafuku, Masato Molecular control of neural stem cells in development and regeneration of mammalian central nervous system. masato.nakafuku@cchmc.org

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Nakamura, Takahisa Molecular mechanism focusing on RNA networks for inter- and intra-cellular communications in the pathogenesis of metabolic diseases, particularly obesity, type 2 diabetes, and non-alcoholic fatty liver diseases. takahisa.nakamura@cchmc.org

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Namekawa, Satoshi Understanding the mechanism and evolution of epigenetic events during mammalian reproduction. satoshi.namekawa@cchmc.org

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Naren, Anjaparavanda Personalized medicine and defining cellular and molecular mechanisms of regulating the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel in diseases such as Cystic Fibrosis and Secretory Diarrhea. 

anaren@cchmc.org

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Norman, Andrew Developing pharmacotherapies for drug abuse using self-administration behavior as a bioassay system to measure the absolute pharmacodynamic and pharmacokinetic potencies of receptor agonists and antagonists. andrew.norman@uc.edu

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Owens, Phillip

The primary focus of my research is to examine the effects of coagulation proteins, proteases, and receptors in the pathogenesis cardiovascular disease (CVD), specifically atherosclerosis and abdominal aortic aneurysms (AAAs).

phillip.owens@uc.edu

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Ozbudak, Ertugrul
We aim to achieve a systems-level understanding of robust spatiotemporal pattern formation (e.g. rhythmic segmentation of somites) and cell fate determination by integrating quantitative experiments with computational modeling. These efforts aim to provide a mechanistic understanding of congenital diseases.

 Ertugrul.Ozbudak@cchmc.org

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Pan, Dao Conducted translational research on in vivo or stem cell-mediated gene therapy for patients with neurological lysosomal storage diseases; interested in CNS pathogenesis and brain drug delivery. Dao.Pan@cchmc.org

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Pasare, Chandrashekhar (Shekhar) Toll-like receptor signaling, Dendritic cell biology and Innate control of adaptive immunity. Goals of our lab are to understand the cellular and molecular mechanisms by which the innate immune system induces inflammation and instructs adaptive immune system to mount protective immune responses against pathogens. Chandrashekhar.Pasare@cchmc.org

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Perl, Anne-Karina Understanding the molecular and cellular mechanisms that regiulate lung fibroblast function and differentitationduring development, alveolar regeneration, fibrosis and lung transplant biology. anne.perl@cchmc.org

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Pestian, John

Dr. Pestian's lab focuses on developing advanced technology for the care of neuropsychiatric illness. The lab also focuses on earlier identification of individuals at risk of suicide, depression, and bipolar and anxiety disorders using verbal and non-verbal language.

john.pestian@cchmc.org

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Pinney, Susan Cancer epidemiology, reproductive epidemiology, screening, environmental biomarkers, exposure metrics, genetic epidemiology, risk communication susan.pinney@uc.edu

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Plas, David We study signal transduction control of oncogenic metabolic programs in cancers of the brain, blood and breast tissues. Our approaches include genetic/genomic analysis, metabolomics, patient-donated tumor models, mouse modeling and cell biology. david.plas@uc.edu

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Qi, Xiaoyang Focused on developing novel theragnostic nanovesicles which have the potential to offer a targeted, potent, broad, and safe therapeutic efficacy and diagnostic application for cancer patient. xiaoyang.qi@cchmc.org

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Qualls, Joseph
Immunology; innate immunity; macrophage biology; amino acid metabolism; intracellular pathogenesis.

joseph.qualls@cchmc.org

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Rance, Mark Application of NMR spectroscopy to macro-molecular structure; The structure/dynamics/function relationship in proteins and protein-nucleic acid complexes. rancema@ucmail.uc.edu

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Ratner, Nancy Development of the nervous system; peripheral nerve tumor formation; Genetic mutations in tumor suppressor genes; Ras signal transduction.

nancy.ratner@cchmc.org

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Reponen, Tiina Indoor allergens and mold; airborne allergens, bacteria, and fungi; exposure assessment in population-based studies. Tiina.Reponen@uc.edu

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Ridgway, William Interested in autoimmunity, immunogenetics, T cells, autoimmune (type I) diabetes, autoimmune liver disease(primary biliary cirrhosis), and relapsing polychondritis. william.ridgway@uc.edu

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Rothenberg, Marc Mechanisms of Allergic Inflammation.Genomic Analysis, Personalized Medicine, and Translational Research Inquiry of Allergy, with focus on Eosinophilic Disorders.

marc.rothenberg@cchmc.org

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Ryan, Patrick Epidemiology; air pollution; exposure assessment.

patrick.ryan@cchmc.org

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Schultz, Jo El Role of opioid peptides and growth factors in cardiovascular function and response to stress and injury; mechanisms and pathology of cardiac function, cardiac growth and ischemia-reperfusion injury; role of growth factors in angiogenesis and ischemia-induced collateralization.
schuljo@ucmail.uc.edu

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Shearn, Jason Create better tissue engineered constructs for implantation and understand the mechanical environment for normal, injured and repairing tendons and ligaments. jason.shearn@uc.edu

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Shin, Soona Mechanisms of liver cancer development with a focus on paracrine interactions and cell identity. Soona.Shin@cchmc.org

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Soleimani, Manoocher Cellular and molecular mechanisms of pH regulation in the kidney. soleimm@ucmail.uc.edu

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Spearman, Paul

Pediatric infectious disease; HIV assembly, HIV biology/pathogenesis, HIV vaccines; vaccines and therapeutics for children (clinical trials).

paul.spearman@cchmc.org

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Starczynowski, Daniel Interested in the molecular, cellular, and genetic basis of hematologic malignancies, with a specific focus on Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML).

daniel.starczynowski@cchmc.org

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Steckl, Andrew Nanoelectronics, biotech materials and devices. a.steckl@uc.edu

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Stottmann, Rolf Developmental neurobiology; genetics; animal models of human congenital defects.

Rolf.Stottmann@cchmc.org

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Sumanas, Saulius Use zebrafish model to investigate molecular mechanisms that regulate cardiovascular development and to investigate genetic causes of human vascular disorders. Saulius.Sumanas@cchmc.org

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Thompson, Thomas Structure-function studies of the TGFbeta family and of apolipoproteins. thompstb@ucmail.uc.edu

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Timberlake, Jeffrey Research interests include the sociology of population, urban sociology, race and ethnicity, and quantitative research methods.  timberjm@ucmail.uc.edu

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Timchenko, Nikolai

Dr. Timchenko is working with molecular mechanisms of Liver Cancer and Non-Alcoholic Fatty Liver Disease. His work focuses on the epigenetic changes that cause these liver diseases.

nikolai.timchenko@cchmc.org

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Tranter, Michael My lab focuses on the molecular mechanisms that drive cardiometabolic diseases. Specific projects focus on the post-transcriptional gene regulation by the RNA binding protein Human antigen R (HuR) in the setting of (1) cardiac fibrosis in hypertrophy and heart failure, (2) inflammation and adaptive cardiac remodeling following ischemia/reperfusion injury, and (3) thermogenesis and metabolic homeostasis in brown and beige adipocytes.

trantemc@ucmail.uc.edu

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Trapnell, Bruce

Research on rare lung diseases including pulmonary alveolar proteinosis, cystic fibrosis, alpha-1 antitrypsin deficiency and lymphangioleiomyomatosis. Mechanisms of alveolar macrophage function. Experimental approaches include molecular techniques using gene knockout, transgenic and conditional gene expression mouse models and non-human primates, in vitro and in vivo viral gene transfer, and bone marrow transplantation.

bruce.trapnell@cchmc.org

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Tso, Patrick Mechanims and regulation of assembly and secretion of triglyceride-rich lipoproteins; role of hypothalamic dysfunction in the development of obesity. tsopp@ucmail.uc.edu

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Ulrich-Lai, Yvonne Identify the neural and hormonal substrates that are responsible for the interactions among diet, obesity and stress. yvonne.ulrich-lai@uc.edu

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Waggoner, Stephen NK cells control vaccine efficacy and disease pathogenesis during infection by killing T cells. Targeting NK-cell immunoregulation may facilitate prevention or treatment of human diseases, including autoimmunity. Stephen.Waggoner@cchmc.org

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Waltz, Susan Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellulartrauma. waltzse@ucmail.uc.edu

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Waxman, Joshua Molecular mechanisms and signaling of organogenesis. Molecular and genetic regulation of cardiovascular
development.
joshua.waxman@cchmc.org

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Way, Sing Sing Individuals are unique vulnerable during in utero development and the early postnatal period. Immunological tools are used investigate susceptibility in these unique developmental windows. singsing.way@cchmc.org

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Weirauch, Matt

The Weirauch lab uses computational and experimental tools to understand the mechanisms of gene transcriptional regulation and how these mechanisms go awry in disease states.

matthew.weirauch@cchmc.org

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Weiss, Alison Research in the Weiss lab focusses on studying the intestinal microbiome and intestinal pathogens using stem-cell derived human intestinal organoids with an emphasis on enteric infectious diseases and cancer. weissaa@ucmail.uc.edu

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Wells, James Edoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. james.wells@cchmc.org

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Wells, Susanne Human papillomavirus, cervical cancer, head and neck cancer, tissue engineering. susanne.wells@cchmc.org

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White, Peter Bioinformatics, biomedical informatics, genome informatics. peter.white@cchmc.org

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Whitsett, Jeffrey Organ morphogenesis, gene regulation, cell differentiation, respiratory disease. jeffrey.whitsett@cchmc.org

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Wikenheiser-Brokamp, Kathryn Molecular and genetic basis of lung development and disease with specific interest in Rb/p16, p53 and Dicer/miRNA signaling pathways. kathryn.wikenheiser-brokamp@cchmc.org

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Woods, Jason Overall goals are to develop state-of-the-art respiratory and cardiac MRI (e.g., with hyperpolarized gases) and CT and to translate these new modalities into the clinic via translational studies.  

jason.woods@cchmc.org

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Woods, Stephen Mechanisms of obesity and its control. woodssc@ucmail.uc.edu

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Yutzey, Katherine Molecular mechanisms of heart development and disease. katherine.yutzey@cchmc.org

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Zacharias, William The Zacharias Lung Lab studies the mechanisms of development and regeneration in the mammalian lung with a focus on gene regulatory networks, epigenetic landscapes, and niche interactions of epithelial progenitor cells. Our goal is to understand why and how lung progenitor cells participate in functional lung regeneration, and identify pathways with therapeutic potential to help patients with acute and chronic lung disease. William.Zacharias@cchmc.org

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Zheng, Yi Molecular mechanisms of Rho GTPase signal transduction. Development of novel therapeutic reagents to inhibit Rho pathways related to human pathological conditions. yi.zheng@cchmc.org

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Zorn, Aaron We use animal models, pluripotent stem cells and cutting-edge genomics to elucidate the gene regulatory networks controlling organogenesis.  This informs the basis of birth defects and strategies to generate human organoid tissue for regenerative medicine. Aaron.Zorn@cchmc.org

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Faculty members.

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  • Pinney Delivers Congressional Briefing
    Susan Pinney, PhD, authored a study – based on 22 years' worth of samples – that details concerns about chemical contamination within drinking water. Dr. Pinney delivered a congressional briefing to the U.S. House of Representatives and to U.S. senators and staff members on this issue.
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