About the Study
Why is This Research Being Done?
The purpose of this study is to determine if adding metformin to a healthy lifestyle program would help children and teens control weight gain caused by certain medications.
This study involves children and teens ages 8-19 years who are overweight with certain mood disorders and who may start or are currently taking a second-generation antipsychotic. Weight gain is a significant concern in this patient population. See recent survey results for more information.
Research Study Facts
This study is being conducted by Dr. Melissa DelBello from the University of Cincinnati in collaboration with Northwell Health and Cincinnati Childrens' Hospital Medical Center.
This study is being funded by PCORI (Patient-Centered Outcomes Research Institute; Award # PCS-1406-19276).
Approximately 1800 youth will be taking part in this study at 24 public and private mental health practices in the Greater Cincinnati and New York City regions.
Study length for each patient is 2 years.
See the Study Promotional Flyer
See a TV segment about the study with a patient story (1 of 2)
See a TV segment about the study with a patient story (2 of 2; starts at
23:07 in video)