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Department of

Psychiatry and Behavioral Neuroscience

Photo of  Paul Keck  Jr., MD

Paul Keck Jr., MD

Professor of Psychiatry, Executive Vice Chair of Psychiatry; and President and CEO of the Lindner Center of HOPE

Education/Credentials
  • Medical Degree: Mount Sinai School of Medicine

Contact Information
  • Stetson Building
  • Suite 3200
  • 260 Stetson Street
  • Cincinnati, Ohio 45219
  • Office 513-558-7700
  • Email paul.keck@uc.edu

Peer Reviewed Publications

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Altshuler, Lori L; Kupka, Ralph W; Hellemann, Gerhard; Frye, Mark A; Sugar, Catherine A; McElroy, Susan L; Nolen, Willem A; Grunze, Heinz; Leverich, Gabriele S; Keck, Paul E; Zermeno, Melanie; Post, Robert M; Suppes, Trisha 2010. Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation bipolar treatment outcome network. The American journal of psychiatry, 167 6, 708-15

Joo, Eun-Jeong; Greenwood, Tiffany A; Schork, Nicholas; McKinney, Rebecca A; Sadovnick, A Dessa; Remick, Ronald A; Keck, Paul E; McElroy, Susan L; Kelsoe, John R 2010. Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 153B 1, 260-8

McElroy, Susan L; Frye, Mark A; Hellemann, Gerhard; Altshuler, Lori; Leverich, Gabriele S; Suppes, Trisha; Keck, Paul E; Nolen, Willem A; Kupka, Ralph; Post, Robert M 2010. Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. Journal of affective disorders, ,

McElroy, Susan L; Martens, Brian E; Creech, Ryan S; Welge, Jeffrey A; Jefferson, Lena; Guerdjikova, Anna I; Keck, Paul E 2010. Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild mania. The Journal of clinical psychiatry, 71 5, 557-65

McElroy, Susan L; Martens, Brian E; Winstanley, Erin L; Creech, Ryan; Malhotra, Shishuka; Keck, Paul E 2010. Placebo-controlled study of quetiapine monotherapy in ambulatory bipolar spectrum disorder with moderate-to-severe hypomania or mild mania. Journal of affective disorders, 124 1-2, 157-63

Altshuler, Lori L; Post, Robert M; Hellemann, Gerhard; Leverich, Gabriele S; Nolen, Willem A; Frye, Mark A; Keck, Paul E; Kupka, Ralph W; Grunze, Heinz; McElroy, Susan L; Sugar, Catherine A; Suppes, Trisha 2009. Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. The Journal of clinical psychiatry, 70 4, 450-7

Frye, Mark A; Helleman, Gerhard; McElroy, Susan L; Altshuler, Lori L; Black, David O; Keck, Paul E; Nolen, Willem A; Kupka, Ralph; Leverich, Gabriele S; Grunze, Heinz; Mintz, Jim; Post, Robert M; Suppes, Trisha 2009. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. The American journal of psychiatry, 166 2, 164-72

Keck, P E; Orsulak, P J; Cutler, A J; Sanchez, R; Torbeyns, A; Marcus, R N; McQuade, R D; Carson, W H 2009. Aripiprazole monotherapy in the treatment of acute bipolar I mania: a randomized, double-blind, placebo- and lithium-controlled study. Journal of affective disorders, 112 1-3, 36-49

Keck, Paul E; Versiani, Marcio; Warrington, Lewis; Loebel, Antony D; Horne, R Lynn 2009. Long-term safety and efficacy of ziprasidone in subpopulations of patients with bipolar mania. The Journal of clinical psychiatry, 70 6, 844-51

McElroy, Susan L; Guerdjikova, Anna I; Martens, Brian; Keck, Paul E; Pope, Harrison G; Hudson, James I 2009. Role of antiepileptic drugs in the management of eating disorders. CNS drugs, 23 2, 139-56

Sheehan, David V; McElroy, Susan L; Harnett-Sheehan, Kathy; Keck, Paul E; Janavs, Juris; Rogers, Jamison; Gonzalez, Robert; Shivakumar, Geetha; Suppes, Trisha 2009. Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety. Journal of affective disorders, 115 3, 376-85

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; McElroy, Susan L; Keck, Paul E; Moss, Quinton; Cerullo, Michael A; Kotwal, Renu; Arndt, Stephan 2009. Characterizing impulsivity in mania. Bipolar disorders, 11 1, 41-51

Anthenelli, Robert M; Blom, Thomas J; McElroy, Susan L; Keck, Paul E 2008. Preliminary evidence for gender-specific effects of topiramate as a potential aid to smoking cessation. Addiction (Abingdon, England), 103 4, 687-94

Evans, Lynn M; Akiskal, Hagop S; Greenwood, Tiffany A; Nievergelt, Caroline M; Keck, Paul E; McElroy, Susan L; Sadovnick, A Dessa; Remick, Ronald A; Schork, Nicholas J; Kelsoe, John R 2008. Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147 3, 326-32

Guerdjikova, Anna I; McElroy, Susan L; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik; Lake, Katie; Alessio, David D'; Keck, Paul E; Hudson, James I 2008. High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial. Human psychopharmacology, 23 1, 1-11

Keck, Paul E; Kessler, Ronald C; Ross, Ruth 2008. Clinical and economic effects of unrecognized or inadequately treated bipolar disorder. Journal of psychiatric practice, 14 Suppl 2 , 31-8

McElroy, Susan L; Bowden, Charles L; Collins, Michelle A; Wozniak, Patricia J; Keck, Paul E; Calabrese, Joseph R 2008. Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorder. Journal of affective disorders, 107 1-3, 127-33

McElroy, Susan L; Nelson, Erik B; Welge, Jeffrey A; Kaehler, Laura; Keck, Paul E 2008. Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial. The Journal of clinical psychiatry, 69 3, 433-40

Post, Robert M; Luckenbaugh, David A; Leverich, Gabriele S; Altshuler, Lori L; Frye, Mark A; Suppes, Trisha; Keck, Paul E; McElroy, Susan L; Nolen, Willem A; Kupka, Ralph; Grunze, Heinz; Walden, Joerg 2008. Incidence of childhood-onset bipolar illness in the USA and Europe. The British journal of psychiatry : the journal of mental science, 192 2, 150-1

Richtand, Neil M; Welge, Jeffrey A; Logue, Aaron D; Keck, Paul E; Strakowski, Stephen M; McNamara, Robert K 2008. Role of serotonin and dopamine receptor binding in antipsychotic efficacy. Progress in brain research, 172 , 155-75

Shivakumar, Geetha; Bernstein, Ira H; Suppes, Trisha ; Keck, Paul E; McElroy, Susan L; Altshuler, Lori L; Frye, Mark A; Nolen, Willem A; Kupka, Ralph W; Grunze, Heinze; Leverich, Gabriele S; Mintz, Jim; Post, Robert M 2008. Are bipolar mood symptoms affected by the phase of the menstrual cycle? Journal of women's health (2002), 17 3, 473-8

Barzman, Drew H; DelBello, Melissa P; Forrester, Jacob J; Keck, Paul E; Strakowski, Stephen M 2007. A retrospective chart review of intramuscular ziprasidone for agitation in children and adolescents on psychiatric units: prospective studies are needed. Journal of child and adolescent psychopharmacology, 17 4, 503-9

Frye, Mark A; Grunze, Heinz; Suppes, Trisha; McElroy, Susan L; Keck, Paul E; Walden, Jorge; Leverich, Gabriele S; Altshuler, Lori L; Nakelsky, Shoshanna; Hwang, Sun; Mintz, Jim; Post, Robert M 2007. A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression. The American journal of psychiatry, 164 8, 1242-9

Guerdjikova, A I; McElroy, S L; Kotwal, R; Keck, P E 2007. Comparison of obese men and women with binge eating disorder seeking weight management. Eating and weight disorders : EWD, 12 1, e19-23

Guerdjikova, Anna I; McElroy, Susan L; Kotwal, Renu; Stanford, Kevin; Keck, Paul E 2007. Psychiatric and metabolic characteristics of childhood versus adult-onset obesity in patients seeking weight management. Eating behaviors, 8 2, 266-76

Guo, Jeff J; Keck, Paul E; Li, Hong; Patel, Nick C 2007. Treatment costs related to bipolar disorder and comorbid conditions among Medicaid patients with bipolar disorder. Psychiatric services (Washington, D.C.), 58 8, 1073-8

Keck, Paul E; Frye, Mark A; Thase, Michael E 2007. Bipolar depression: best practices for the hospitalized patient. CNS spectrums, 12 11 Suppl 19, 1-13

Leverich, Gabriele S; Post, Robert M; Keck, Paul E; Altshuler, Lori L; Frye, Mark A; Kupka, Ralph W; Nolen, Willem A; Suppes, Trisha; McElroy, Susan L; Grunze, Heinz; Denicoff, Kirk; Moravec, Maria K M; Luckenbaugh, David 2007. The poor prognosis of childhood-onset bipolar disorder. The Journal of pediatrics, 150 5, 485-90

McElroy, Susan L; Guerdjikova, Anna; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; Keck, Paul E; Hudson, James I 2007. Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial. The Journal of clinical psychiatry, 68 3, 390-8

Richtand, Neil M; Welge, Jeffrey A; Logue, Aaron D; Keck, Paul E; Strakowski, Stephen M; McNamara, Robert K 2007. Dopamine and serotonin receptor binding and antipsychotic efficacy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 32 8, 1715-26

Suppes, Trisha; Kelly, Dorothy I; Keck, Paul E; McElroy, Susan L; Altshuler, Lori L; Mintz, Jim; Frye, Mark A; Nolen, Willem A; Luckenbaugh, David A; Post, Robert M; Leverich, Gabriele S; Kupka, Ralph W; Grunze, Heinz 2007. Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network. International clinical psychopharmacology, 22 6, 376-81

Altshuler, Lori L; Post, Robert M; Black, David O; Keck, Paul E; Nolen, Willem A; Frye, Mark A; Suppes, Trisha; Grunze, Heinz; Kupka, Ralph W; Leverich, Gabriele S; McElroy, Susan L; Walden, Joerg; Mintz, Jim 2006. Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study. The Journal of clinical psychiatry, 67 10, 1551-60

Arnold, Lesley M; Hudson, James I; Keck, Paul E; Auchenbach, Megan B; Javaras, Kristin N; Hess, Evelyn V 2006. Comorbidity of fibromyalgia and psychiatric disorders. The Journal of clinical psychiatry, 67 8, 1219-25

Brown, Eileen B; McElroy, Susan L; Keck, Paul E; Deldar, Ahmed; Adams, David H; Tohen, Mauricio; Williamson, Douglas J 2006. A 7-week, randomized, double-blind trial of olanzapine/fluoxetine combination versus lamotrigine in the treatment of bipolar I depression. The Journal of clinical psychiatry, 67 7, 1025-33

Corya, Sara A; Perlis, Roy H; Keck, Paul E; Lin, Daniel Y; Case, Michael G; Williamson, Doug J; Tohen, Mauricio F 2006. A 24-week open-label extension study of olanzapine-fluoxetine combination and olanzapine monotherapy in the treatment of bipolar depression. The Journal of clinical psychiatry, 67 5, 798-806

Guo, Jeff J; Keck, Paul E; Corey-Lisle, Patricia K; Li, Hong; Jiang, Dongming; Jang, Raymond; L'Italien, Gilbert J 2006. Risk of diabetes mellitus associated with atypical antipsychotic use among patients with bipolar disorder: A retrospective, population-based, case-control study. The Journal of clinical psychiatry, 67 7, 1055-61

Keck, Paul E 2006. Long-term management strategies to achieve optimal function in patients with bipolar disorder. The Journal of clinical psychiatry, 67 12, e17

Keck, Paul E; Calabrese, Joseph R; McQuade, Robert D; Carson, William H; Carlson, Berit X; Rollin, Linda M; Marcus, Ronald N; Sanchez, Raymond 2006. A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorder. The Journal of clinical psychiatry, 67 4, 626-37

Keck, Paul E; Mintz, Jim; McElroy, Susan L; Freeman, Marlene P; Suppes, Trisha; Frye, Mark A; Altshuler, Lori L; Kupka, Ralph; Nolen, Willem A; Leverich, Gabriele S; Denicoff, Kirk D; Grunze, Heinz; Duan, Naihua; Post, Robert M 2006. Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biological psychiatry, 60 9, 1020-2

Kotwal, Renu; Guerdjikova, Anna; McElroy, Susan L; Keck, Paul E 2006. Lithium augmentation of topiramate for bipolar disorder with comorbid binge eating disorder and obesity. Human psychopharmacology, 21 7, 425-31

Leverich, Gabriele S; Altshuler, Lori L; Frye, Mark A; Suppes, Trisha; McElroy, Susan L; Keck, Paul E; Kupka, Ralph W; Denicoff, Kirk D; Nolen, Willem A; Grunze, Heinz; Martinez, Maria I; Post, Robert M 2006. Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers. The American journal of psychiatry, 163 2, 232-9

McElroy, Susan L; Kotwal, Renu; Guerdjikova, Anna I; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; D'Alessio, David A; Keck, Paul E; Hudson, James I 2006. Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. The Journal of clinical psychiatry, 67 12, 1897-906

McElroy, Susan L; Kotwal, Renu; Kaneria, Rakesh; Keck, Paul E 2006. Antidepressants and suicidal behavior in bipolar disorder. Bipolar disorders, 8 5 Pt 2, 596-617

McElroy, Susan L; Kotwal, Renu; Keck, Paul E 2006. Comorbidity of eating disorders with bipolar disorder and treatment implications. Bipolar disorders, 8 6, 686-95

Nievergelt, Caroline M; Kripke, Daniel F; Barrett, Thomas B; Burg, Elyssa; Remick, Ronald A; Sadovnick, A Dessa; McElroy, Susan L; Keck, Paul E; Schork, Nicholas J; Kelsoe, John R 2006. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 141B 3, 234-41

Post, R M; Altshuler, L L; Leverich, G S; Frye, M A; Nolen, W A; Kupka, R W; Suppes, T; McElroy, S; Keck, P E; Denicoff, K D; Grunze, H; Walden, J; Kitchen, C M R; Mintz, J 2006. Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. The British journal of psychiatry : the journal of mental science, 189 , 124-31

Post, Robert M; Altshuler, Lori L; Frye, Mark A; Suppes, Trisha; McElroy, Susan; Keck, Paul E; Leverich, Gabriele S; Kupka, Ralph; Nolen, Willem A; Grunze, Heinz 2006. New findings from the Bipolar Collaborative Network: clinical implications for therapeutics. Current psychiatry reports, 8 6, 489-97

Strawn, Jeffrey R; Keck, Paul E 2006. Early bicarbonate loading and dantroline for ziprasidone/haloperidol-induced neuroleptic malignant syndrome. The Journal of clinical psychiatry, 67 4, 677

Akiskal, Hagop S; Fuller, Matthew A; Hirschfeld, Robert M A; Keck, Paul E; Ketter, Terence A; Weisler, Richard H 2005. Reassessing carbamazepine in the treatment of bipolar disorder: clinical implications of new data. CNS spectrums, 10 6, suppl 1-11; discuss

Calabrese, Joseph R; Keck, Paul E; Bowden, Charles L; Ketter, Terence A; Sachs, Gary; Findling, Robert L; Sajatovic, Martha 2005. A US perspective of the CANMAT bipolar guidelines. Bipolar disorders, 7 Suppl 3 , 70-2

Evans, Lynn; Akiskal, Hagop S; Keck, Paul E; McElroy, Susan L; Sadovnick, A Dessa; Remick, Ronald A; Kelsoe, John R 2005. Familiality of temperament in bipolar disorder: support for a genetic spectrum. Journal of affective disorders, 85 1-2, 153-68

Fleck, David E; Keck, Paul E; Corey, Kimberly B; Strakowski, Stephen M 2005. Factors associated with medication adherence in African American and white patients with bipolar disorder. The Journal of clinical psychiatry, 66 5, 646-52

Keck, Paul E 2005. Bipolar depression: a new role for atypical antipsychotics? Bipolar disorders, 7 Suppl 4 , 34-40

Keck, Paul E; Corya, Sara A; Altshuler, Lori L; Ketter, Terence A; McElroy, Susan L; Case, Michael; Briggs, Susan D; Tohen, Mauricio 2005. Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depression. The Journal of clinical psychiatry, 66 5, 611-6

McElroy, Susan L; Kotwal, Renu; Keck, Paul E; Akiskal, Hagop S 2005. Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations? Journal of affective disorders, 86 2-3, 107-27

McElroy, Susan L; Suppes, Trisha; Keck, Paul E; Black, David; Frye, Mark A; Altshuler, Lori L; Nolen, Willem A; Kupka, Ralph W; Leverich, Gabriele S; Walden, Jorg; Grunze, Heinz; Post, Robert M 2005. Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial. The Journal of clinical psychiatry, 66 5, 617-24

Nievergelt, Caroline M; Kripke, Daniel F; Remick, Ronald A; Sadovnick, A Dessa; McElroy, Susan L; Keck, Paul E; Kelsoe, John R 2005. Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association. Psychiatric genetics, 15 1, 45-52

Perlis, Roy H; Keck, Paul E 2005. The Texas implementation of medication algorithms update for treatment of bipolar I disorder. The Journal of clinical psychiatry, 66 7, 818-20

Post, Robert M; Altshuler, Lori L; Frye, Mark A; Suppes, Trisha; McElroy, Susan L; Keck, Paul E; Leverich, Gabriele S; Kupka, Ralph; Nolen, Willem A; Luckenbaugh, David A; Walden, Jorg; Grunze, Heinz 2005. Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder. The Journal of clinical psychiatry, 66 3, 370-4

Rasgon, Natalie L; Altshuler, Lori L; Fairbanks, Lynn; Elman, Shana; Bitran, Jose; Labarca, Rodrigo; Saad, Mohammed; Kupka, Ralph; Nolen, Willem A; Frye, Mark A; Suppes, Trisha; McElroy, Susan L; Keck, Paul E; Leverich, Gabriele; Grunze, Heinz; Walden, Joerg; Post, Robert; Mintz, Jim 2005. Reproductive function and risk for PCOS in women treated for bipolar disorder. Bipolar disorders, 7 3, 246-59

Revicki, Dennis A; Hirschfeld, Robert M A; Ahearn, Eileen P; Weisler, Richard H; Palmer, Cynthia; Keck, Paul E 2005. Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial. Journal of affective disorders, 86 2-3, 183-93

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2005. Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. Archives of general psychiatry, 62 8, 851-8

Arnold, Lesley M; Keck, Paul E; Collins, Jacqueline; Wilson, Rodgers; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R; Strakowski, Stephen M 2004. Ethnicity and first-rank symptoms in patients with psychosis. Schizophrenia research, 67 2-3, 207-12

Hirschfeld, Robert M A; Keck, Paul E; Kramer, Michelle; Karcher, Keith; Canuso, Carla; Eerdekens, Marielle; Grossman, Fred 2004. Rapid antimanic effect of risperidone monotherapy: a 3-week multicenter, double-blind, placebo-controlled trial. The American journal of psychiatry, 161 6, 1057-65

Hudson, James I; Arnold, Lesley M; Keck, Paul E; Auchenbach, Megan B; Pope, Harrison G 2004. Family study of fibromyalgia and affective spectrum disorder. Biological psychiatry, 56 11, 884-91

Keck, Paul E 2004. Evaluation and management of breakthrough depressive episodes. The Journal of clinical psychiatry, 65 Suppl 10 , 11-5

McElroy, Susan L; Kotwal, Renu; Hudson, James I; Nelson, Erik B; Keck, Paul E 2004. Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial. The Journal of clinical psychiatry, 65 1, 50-6

McElroy, Susan L; Kotwal, Renu; Malhotra, Shishuka; Nelson, Erik B; Keck, Paul E; Nemeroff, Charles B 2004. Are mood disorders and obesity related? A review for the mental health professional. The Journal of clinical psychiatry, 65 5, 634-51, quiz 730

Nolen, Willem A; Luckenbaugh, David A; Altshuler, Lori L; Suppes, Trisha; McElroy, Susan L; Frye, Mark A; Kupka, Ralph W; Keck, Paul E; Leverich, Gabriele S; Post, Robert M 2004. Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network. The American journal of psychiatry, 161 8, 1447-54

Altshuler, Lori; Suppes, Trisha; Black, David; Nolen, Willem A; Keck, Paul E; Frye, Mark A; McElroy, Susan; Kupka, Ralph; Grunze, Heinz; Walden, Jörg; Leverich, Gabrielle; Denicoff, Kirk; Luckenbaugh, David; Post, Robert 2003. Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. The American journal of psychiatry, 160 7, 1252-62

Baldessarini, Ross J; Hennen, John; Wilson, Michael; Calabrese, Joseph; Chengappa, Roy; Keck, Paul E; McElroy, Susan L; Sachs, Gary; Vieta, Eduard; Welge, Jeffrey A; Yatham, Lakshmi N; Zarate, Carlos A; Baker, Robert W; Tohen, Mauricio 2003. Olanzapine versus placebo in acute mania: treatment responses in subgroups. Journal of clinical psychopharmacology, 23 4, 370-6

Barrett, T B; Hauger, R L; Kennedy, J L; Sadovnick, A D; Remick, R A; Keck, P E; McElroy, S L; Alexander, M; Shaw, S H; Kelsoe, J R 2003. Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder. Molecular psychiatry, 8 5, 546-57

Calabrese, Joseph R; Hirschfeld, Robert M A; Reed, Michael; Davies, Marilyn A; Frye, Mark A; Keck, Paul E; Lewis, Lydia; McElroy, Susan L; McNulty, James P; Wagner, Karen D 2003. Impact of bipolar disorder on a U.S. community sample. The Journal of clinical psychiatry, 64 4, 425-32

Dewan, Naakesh A; Conley, Douglas; Svendsen, Dale; Shon, Steven P; Staup, John R; Miller, Alexander L; Crismon, M Lynn; Rush, A John; Trivedi, Madhukar; Skale, Tracy; Keck, Paul E; Strawkowski, Stephen M 2003. A quality improvement process for implementing the Texas algorithm for schizophrenia in Ohio. Psychiatric services (Washington, D.C.), 54 12, 1646-9

Frye, Mark A; Altshuler, Lori L; McElroy, Susan L; Suppes, Trisha; Keck, Paul E; Denicoff, Kirk; Nolen, Willem A; Kupka, Ralph; Leverich, Gabriele S; Pollio, Chad; Grunze, Heinz; Walden, Jorge; Post, Robert M 2003. Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder. The American journal of psychiatry, 160 5, 883-9

Gyulai, Laszlo; Bowden, Charles L; McElroy, Susan L; Calabrese, Joseph R; Petty, Frederick; Swann, Alan C; Chou, James C-Y; Wassef, Adel; Risch, Craig S; Hirschfeld, Robert M A; Nemeroff, Charles B; Keck, Paul E; Evans, Dwight L; Wozniak, Patricia J 2003. Maintenance efficacy of divalproex in the prevention of bipolar depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28 7, 1374-82

Hirschfeld, Robert M A; Calabrese, Joseph R; Weissman, Myrna M; Reed, Michael; Davies, Marilyn A; Frye, Mark A; Keck, Paul E; Lewis, Lydia; McElroy, Susan L; McNulty, James P; Wagner, Karen D 2003. Screening for bipolar disorder in the community. The Journal of clinical psychiatry, 64 1, 53-9

Keck, Paul E 2003. The management of acute mania. BMJ (Clinical research ed.), 327 7422, 1002-3

Keck, Paul E; McElroy, Susan L 2003. Bipolar disorder, obesity, and pharmacotherapy-associated weight gain. The Journal of clinical psychiatry, 64 12, 1426-35

Keck, Paul E; McElroy, Susan L 2003. Aripiprazole: a partial dopamine D2 receptor agonist antipsychotic. Expert opinion on investigational drugs, 12 4, 655-62

Keck, Paul E; McElroy, Susan L 2003. Redefining mood stabilization. Journal of affective disorders, 73 1-2, 163-9

Keck, Paul E; McElroy, Susan L 2003. New approaches in managing bipolar depression. The Journal of clinical psychiatry, 64 Suppl 1 , 13-8

Keck, Paul E; McElroy, Susan L 2003. Divalproex in the treatment of bipolar disorder. Psychopharmacology bulletin, 37 Suppl 2 , 67-73

Keck, Paul E; Versiani, Marcio; Potkin, Steven; West, Scott A; Giller, Earl; Ice, Kathleen 2003. Ziprasidone in the treatment of acute bipolar mania: a three-week, placebo-controlled, double-blind, randomized trial. The American journal of psychiatry, 160 4, 741-8

Post, Robert M; Denicoff, Kirk D; Leverich, Gabriele S; Altshuler, Lori L; Frye, Mark A; Suppes, Trisha M; Rush, A John; Keck, Paul E; McElroy, Susan L; Luckenbaugh, David A; Pollio, Chad; Kupka, Ralph; Nolen, Willem A 2003. Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. The Journal of clinical psychiatry, 64 6, 680-90; quiz 738-9

Shaw, S H; Mroczkowski-Parker, Z; Shekhtman, T; Alexander, M; Remick, R A; Sadovnick, A D; McElroy, S L; Keck, P E; Kelsoe, J R 2003. Linkage of a bipolar disorder susceptibility locus to human chromosome 13q32 in a new pedigree series. Molecular psychiatry, 8 5, 558-64

Strakowski, Stephen M; Del Bello, Melissa P; Adler, Caleb M; Keck, Paul E 2003. Atypical antipsychotics in the treatment of bipolar disorder. Expert opinion on pharmacotherapy, 4 5, 751-60

Strakowski, Stephen M; Keck, Paul E; Arnold, Lesley M; Collins, Jacqueline; Wilson, Rodgers M; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R 2003. Ethnicity and diagnosis in patients with affective disorders. The Journal of clinical psychiatry, 64 7, 747-54

Arnold, Lesley M; Hess, Evelyn V; Hudson, James I; Welge, Jeffrey A; Berno, Sarah E; Keck, Paul E 2002. A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. The American journal of medicine, 112 3, 191-7

Arnold, Lesley M; McElroy, Susan L; Hudson, James I; Welge, Jeffrey A; Bennett, Aurora J; Keck, Paul E 2002. A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorder. The Journal of clinical psychiatry, 63 11, 1028-33

Charney, Dennis S; Nemeroff, Charles B; Lewis, Lydia; Laden, Sally K; Gorman, Jack M; Laska, Eugene M; Borenstein, Michael; Bowden, Charles L; Caplan, Arthur; Emslie, Graham J; Evans, Dwight L; Geller, Barbara; Grabowski, Lenore E; Herson, Jay; Kalin, Ned H; Keck, Paul E; Kirsch, Irving; Krishnan, K Ranga R; Kupfer, David J; Makuch, Robert W; Miller, Franklin G; Pardes, Herbert; Post, Robert; Reynolds, Mildred M; Roberts, Laura; Rosenbaum, Jerrold F; Rosenstein, Donald L; Rubinow, David R; Rush, A John; Ryan, Neal D; Sachs, Gary S; Schatzberg, Alan F; Solomon, Susan 2002. National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Archives of general psychiatry, 59 3, 262-70

Greenwood, T A; Alexander, M; Keck, P E; McElroy, S; Sadovnick, A D; Remick, R A; Shaw, S H; Kelsoe, J R 2002. Segmental linkage disequilibrium within the dopamine transporter gene. Molecular psychiatry, 7 2, 165-73

Keck, P E; McElroy, S L; Richtand, N; Tohen, M 2002. What makes a drug a primary mood stabilizer? Molecular psychiatry, 7 Suppl 1 , S8-14

Keck, Paul E; McElroy, Susan L 2002. Carbamazepine and valproate in the maintenance treatment of bipolar disorder. The Journal of clinical psychiatry, 63 Suppl 10 , 13-7

Keck, Paul E; McElroy, Susan L 2002. Clinical pharmacodynamics and pharmacokinetics of antimanic and mood-stabilizing medications. The Journal of clinical psychiatry, 63 Suppl 4 , 3-11

Kupka, Ralph W; Nolen, Willem A; Post, Robert M; McElroy, Susan L; Altshuler, Lori L; Denicoff, Kirk D; Frye, Mark A; Keck, Paul E; Leverich, Gabriele S; Rush, A John; Suppes, Trisha; Pollio, Chad; Drexhage, Hemmo A 2002. High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure. Biological psychiatry, 51 4, 305-11

McElroy, Susan L; Frye, Mark A; Suppes, Trisha; Dhavale, Dawn; Keck, Paul E; Leverich, Gabriele S; Altshuler, Lori; Denicoff, Kirk D; Nolen, Willem A; Kupka, Ralph; Grunze, Heinz; Walden, Jorg; Post, Robert M 2002. Correlates of overweight and obesity in 644 patients with bipolar disorder. The Journal of clinical psychiatry, 63 3, 207-13

Namjoshi, Madhav A; Rajamannar, Gopalan; Jacobs, Thomas; Sanger, Todd M; Risser, Richard; Tohen, Mauricio F; Breier, Alan; Keck, Paul E 2002. Economic, clinical, and quality-of-life outcomes associated with olanzapine treatment in mania. Results from a randomized controlled trial. Journal of affective disorders, 69 1-3, 109-18

Soutullo, Cesar A; DelBello, Melissa P; Ochsner, Jennifer E; McElroy, Susan L; Taylor, Siobhan A; Strakowski, Stephen M; Keck, Paul E 2002. Severity of bipolarity in hospitalized manic adolescents with history of stimulant or antidepressant treatment. Journal of affective disorders, 70 3, 323-7

Suppes, Trisha; Chisholm, Karrie A; Dhavale, Dawn; Frye, Mark A; Altshuler, Lori L; McElroy, Susan L; Keck, Paul E; Nolen, Willem A; Kupka, Ralph; Denicoff, Kirk D; Leverich, Gabrielle S; Rush, A John; Post, Robert M 2002. Tiagabine in treatment refractory bipolar disorder: a clinical case series. Bipolar disorders, 4 5, 283-9

Suppes, Trisha; Dennehy, Ellen B; Swann, Alan C; Bowden, Charles L; Calabrese, Joseph R; Hirschfeld, Robert M A; Keck, Paul E; Sachs, Gary S; Crismon, M Lynn; Toprac, Marcia G; Shon, Steven P 2002. Report of the Texas Consensus Conference Panel on medication treatment of bipolar disorder 2000. The Journal of clinical psychiatry, 63 4, 288-99

Calabrese, J R; Keck, P E; McElroy, S L; Shelton, M D 2001. A pilot study of topiramate as monotherapy in the treatment of acute mania. Journal of clinical psychopharmacology, 21 3, 340-2

Freeman, M P; Keck , P E; McElroy, S L 2001. Postpartum depression with bipolar disorder. The American journal of psychiatry, 158 4, 652

Geracioti, T D; Baker, D G; Ekhator, N N; West, S A; Hill, K K; Bruce, A B; Schmidt, D; Rounds-Kugler, B; Yehuda, R; Keck, P E; Kasckow, J W 2001. CSF norepinephrine concentrations in posttraumatic stress disorder. The American journal of psychiatry, 158 8, 1227-30

Greenwood, T A; Alexander, M; Keck, P E; McElroy, S; Sadovnick, A D; Remick, R A; Kelsoe, J R 2001. Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder. American journal of medical genetics, 105 2, 145-51

Hudson, J I; Laird, N M; Betensky, R A; Keck, P E; Pope, H G 2001. Multivariate logistic regression for familial aggregation of two disorders. II. Analysis of studies of eating and mood disorders. American journal of epidemiology, 153 5, 506-14

Janicak, P G; Keck, P E; Davis, J M; Kasckow, J W; Tugrul, K; Dowd, S M; Strong, J; Sharma, R P; Strakowski, S M 2001. A double-blind, randomized, prospective evaluation of the efficacy and safety of risperidone versus haloperidol in the treatment of schizoaffective disorder. Journal of clinical psychopharmacology, 21 4, 360-8

Keck, P E; McElroy, S L 2001. Definition, evaluation, and management of treatment refractory mania. Psychopharmacology bulletin, 35 4, 130-48

Keck, P E; McElroy, S L; Arnold, L M 2001. Ziprasidone: a new atypical antipsychotic. Expert opinion on pharmacotherapy, 2 6, 1033-42

Keck, P E; McElroy, S L; Arnold, L M 2001. Bipolar disorder. The Medical clinics of North America, 85 3, 645-61, ix

Keck, P E; Strakowski, S M; Hawkins, J M; Dunayevich, E; Tugrul, K C; Bennett, J A; McElroy, S L 2001. A pilot study of rapid lithium administration in the treatment of acute mania. Bipolar disorders, 3 2, 68-72

Kupka, R W; Nolen, W A; Altshuler, L L; Denicoff, K D; Frye, M A; Leverich, G S; Keck, P E; McElroy, S L; Rush, A J; Suppes, T; Post, R M 2001. The Stanley Foundation Bipolar Network. 2. Preliminary summary of demographics, course of illness and response to novel treatments. The British journal of psychiatry. Supplement, 41 , s177-83

McElroy, S L; Altshuler, L L; Suppes, T; Keck, P E; Frye, M A; Denicoff, K D; Nolen, W A; Kupka, R W; Leverich, G S; Rochussen, J R; Rush, A J; Post, R M 2001. Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. The American journal of psychiatry, 158 3, 420-6

Post, R M; Altshuler, L L; Frye, M A; Suppes, T; Rush, A J; Keck, P E; McElroy, S L; Denicoff, K D; Leverich, G S; Kupka, R; Nolen, W A 2001. Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers. Bipolar disorders, 3 5, 259-65

Denicoff, K D; Leverich, G S; Nolen, W A; Rush, A J; McElroy, S L; Keck, P E; Suppes, T; Altshuler, L L; Kupka, R; Frye, M A; Hatef, J; Brotman, M A; Post, R M 2000. Validation of the prospective NIMH-Life-Chart Method (NIMH-LCM-p) for longitudinal assessment of bipolar illness. Psychological medicine, 30 6, 1391-7

Dunayevich, E; Sax, K W; Keck, P E; McElroy, S L; Sorter, M T; McConville, B J; Strakowski, S M 2000. Twelve-month outcome in bipolar patients with and without personality disorders. The Journal of clinical psychiatry, 61 2, 134-9

Keck, P E; McElroy, S L; Bennett, J A 2000. Pharmacologic loading in the treatment of acute mania. Bipolar disorders, 2 1, 42-6

Keck, P E; McElroy, S L; Strakowski, S M; Soutullo, C A 2000. Antipsychotics in the treatment of mood disorders and risk of tardive dyskinesia. The Journal of clinical psychiatry, 61 Suppl 4 , 33-8

Keck, P E; Strakowski, S M; McElroy, S L 2000. The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia. The Journal of clinical psychiatry, 61 Suppl 3 , 4-9

Keck, P E; Welge, J A; McElroy, S L; Arnold, L M; Strakowski, S M 2000. Placebo effect in randomized, controlled studies of acute bipolar mania and depression. Biological psychiatry, 47 8, 748-55

Keck, P E; Welge, J A; Strakowski, S M; Arnold, L M; McElroy, S L 2000. Placebo effect in randomized, controlled maintenance studies of patients with bipolar disorder. Biological psychiatry, 47 8, 756-61

Kornberg, J R; Brown, J L; Sadovnick, A D; Remick, R A; Keck, P E; McElroy, S L; Rapaport, M H; Thompson, P M; Kaul, J B; Vrabel, C M; Schommer, S C; Wilson, T; Pizzuco, D; Jameson, S; Schibuk, L; Kelsoe, J R 2000. Evaluating the parent-of-origin effect in bipolar affective disorder. Is a more penetrant subtype transmitted paternally? Journal of affective disorders, 59 3, 183-92

McElroy, S L; Keck, P E 2000. Pharmacologic agents for the treatment of acute bipolar mania. Biological psychiatry, 48 6, 539-57

McElroy, S L; Suppes, T; Keck, P E; Frye, M A; Denicoff, K D; Altshuler, L L; Brown, E S; Nolen, W A; Kupka, R W; Rochussen, J; Leverich, G S; Post, R M 2000. Open-label adjunctive topiramate in the treatment of bipolar disorders. Biological psychiatry, 47 12, 1025-33

Rush, A J; Post, R M; Nolen, W A; Keck, P E; Suppes, T; Altshuler, L; McElroy, S L 2000. Methodological issues in developing new acute treatments for patients with bipolar illness. Biological psychiatry, 48 6, 615-24

Tsevat, J; Keck, P E; Hornung, R W; McElroy, S L 2000. Health values of patients with bipolar disorder. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 9 5, 579-86

Altshuler, L L; Keck, P E; McElroy, S L; Suppes, T; Brown, E S; Denicoff, K; Frye, M; Gitlin, M; Hwang, S; Goodman, R; Leverich, G; Nolen, W; Kupka, R; Post, R 1999. Gabapentin in the acute treatment of refractory bipolar disorder. Bipolar disorders, 1 1, 61-5

Calabrese, J R; Bowden, C L; McElroy, S L; Cookson, J; Andersen, J; Keck, P E; Rhodes, L; Bolden-Watson, C; Zhou, J; Ascher, J A 1999. Spectrum of activity of lamotrigine in treatment-refractory bipolar disorder. The American journal of psychiatry, 156 7, 1019-23

DelBello, M P; Strakowski, S M; Sax, K W; McElroy, S L; Keck, P E; West, S A; Kmetz, G F 1999. Familial rates of affective and substance use disorders in patients with first-episode mania. Journal of affective disorders, 56 1, 55-60

Geracioti, T D; West, S A; Baker, D G; Hill, K K; Ekhator, N N; Wortman, M D; Keck, P E; Norman, A B 1999. Low CSF concentration of a dopamine metabolite in tobacco smokers. The American journal of psychiatry, 156 1, 130-2

Goldsmith, T B; Shapira, N A; Keck, P E 1999. Rapid remission of OCD with tramadol hydrochloride. The American journal of psychiatry, 156 4, 660-1

Hirschfeld, R M; Allen, M H; McEvoy, J P; Keck, P E; Russell, J M 1999. Safety and tolerability of oral loading divalproex sodium in acutely manic bipolar patients. The Journal of clinical psychiatry, 60 12, 815-8

Keck, P E; McElroy, S L; Strakowski, S M 1999. Schizoaffective disorder: role of atypical antipsychotics. Schizophrenia research, 35 Suppl , S5-12

McElroy, S L; Keck, P E; Strakowski, S M 1999. An overview of the treatment of schizoaffective disorder. The Journal of clinical psychiatry, 60 Suppl 5 , 16-21; discussion 22

McElroy, S L; Soutullo, C A; Taylor, P; Nelson, E B; Beckman, D A; Brusman, L A; Ombaba, J M; Strakowski, S M; Keck, P E 1999. Psychiatric features of 36 men convicted of sexual offenses. The Journal of clinical psychiatry, 60 6, 414-20; quiz 421-2

Shapira, N A; DelBello, M P; Goldsmith, T D; Rosenberger, B M; Keck, P E 1999. Evaluation of bipolar disorder in inpatients with prelingual deafness. The American journal of psychiatry, 156 8, 1267-9

Soutullo, C A; Sorter, M T; Foster, K D; McElroy, S L; Keck, P E 1999. Olanzapine in the treatment of adolescent acute mania: a report of seven cases. Journal of affective disorders, 53 3, 279-83

Suppes, T; Brown, E S; McElroy, S L; Keck, P E; Nolen, W; Kupka, R; Frye, M; Denicoff, K D; Altshuler, L; Leverich, G S; Post, R M 1999. Lamotrigine for the treatment of bipolar disorder: a clinical case series. Journal of affective disorders, 53 1, 95-8

Berardi, D; Amore, M; Keck, P E; Troia, M; Dell'Atti, M 1998. Clinical and pharmacologic risk factors for neuroleptic malignant syndrome: a case-control study. Biological psychiatry, 44 8, 748-54

Chang, K D; Keck, P E; Stanton, S P; McElroy, S L; Strakowski, S M; Geracioti, T D 1998. Differences in thyroid function between bipolar manic and mixed states. Biological psychiatry, 43 10, 730-3

Geracioti, T D; Keck, P E; Ekhator, N N; West, S A; Baker, D G; Hill, K K; Bruce, A B; Wortman, M D 1998. Continuous covariability of dopamine and serotonin metabolites in human cerebrospinal fluid. Biological psychiatry, 44 3, 228-33

Keck, P E; McElroy, S L; Strakowski, S M; West, S A; Sax, K W; Hawkins, J M; Bourne, M L; Haggard, P 1998. 12-month outcome of patients with bipolar disorder following hospitalization for a manic or mixed episode. The American journal of psychiatry, 155 5, 646-52

Linder, M W; Keck, P E 1998. Standards of laboratory practice: antidepressant drug monitoring. National Academy of Clinical Biochemistry. Clinical chemistry, 44 5, 1073-84

McElroy, S L; Frye, M; Denicoff, K; Altshuler, L; Nolen, W; Kupka, R; Suppes, T; Keck, P E; Leverich, G S; Kmetz, G F; Post, R M 1998. Olanzapine in treatment-resistant bipolar disorder. Journal of affective disorders, 49 2, 119-22

McElroy, S L; Soutullo, C A; Beckman, D A; Taylor, P; Keck, P E 1998. DSM-IV intermittent explosive disorder: a report of 27 cases. The Journal of clinical psychiatry, 59 4, 203-10; quiz 211

Sax, K W; Strakowski, S M; Keck, P E 1998. Attentional improvement following quetiapine fumarate treatment in schizophrenia. Schizophrenia research, 33 3, 151-5

Sax, K W; Strakowski, S M; Keck, P E; McElroy, S L; West, S A; Stanton, S P 1998. Symptom correlates of attentional improvement following hospitalization for a first episode of affective psychosis. Biological psychiatry, 44 8, 784-6

Soutullo, C A; McElroy, S L; Keck, P E 1998. Hypomania associated with mirtazapine augmentation of sertraline. The Journal of clinical psychiatry, 59 6, 320

Strakowski, S M; Keck, P E; McElroy, S L; West, S A; Sax, K W; Hawkins, J M; Kmetz, G F; Upadhyaya, V H; Tugrul, K C; Bourne, M L 1998. Twelve-month outcome after a first hospitalization for affective psychosis. Archives of general psychiatry, 55 1, 49-55

Strakowski, S M; Sax, K W; McElroy, S L; Keck, P E; Hawkins, J M; West, S A 1998. Course of psychiatric and substance abuse syndromes co-occurring with bipolar disorder after a first psychiatric hospitalization. The Journal of clinical psychiatry, 59 9, 465-71

Baker, D G; West, S A; Orth, D N; Hill, K K; Nicholson, W E; Ekhator, N N; Bruce, A B; Wortman, M D; Keck, P E; Geracioti, T D 1997. Cerebrospinal fluid and plasma beta-endorphin in combat veterans with post-traumatic stress disorder. Psychoneuroendocrinology, 22 7, 517-29

Keck, P E; McElroy, S L 1997. New uses for antidepressants: social phobia. The Journal of clinical psychiatry, 58 Suppl 14 , 32-6; discussion 37-

Keck, P E; McElroy, S L; Strakowski, S M; Bourne, M L; West, S A 1997. Compliance with maintenance treatment in bipolar disorder. Psychopharmacology bulletin, 33 1, 87-91

Sax, K W; Strakowski, S M; Keck, P E; McElroy, S L; West, S A; Bourne, M L; Larson, E R 1997. Comparison of patients with early-, typical-, and late-onset affective psychosis. The American journal of psychiatry, 154 9, 1299-301

Shapira, N A; Keck, P E; Goldsmith, T D; McConville, B J; Eis, M; McElroy, S L 1997. Open-label pilot study of tramadol hydrochloride in treatment-refractory obsessive-compulsive disorder. Depression and anxiety, 6 4, 170-3

Shapira, N A; McConville, B J; Pagnucco, M L; Norman, A B; Keck, P E 1997. Novel use of tramadol hydrochloride in the treatment of Tourette's syndrome. The Journal of clinical psychiatry, 58 4, 174-5

Stanton, S P; Keck, P E; McElroy, S L 1997. Treatment of acute mania with gabapentin. The American journal of psychiatry, 154 2, 287

Strakowski, S M; Sax, K W; Setters, M J; Stanton, S P; Keck, P E 1997. Lack of enhanced response to repeated d-amphetamine challenge in first-episode psychosis: implications for a sensitization model of psychosis in humans. Biological psychiatry, 42 9, 749-55

Bennett, J A; Keck, P E 1996. A target-dose finding study of clozapine in patients with schizophrenia. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 8 1, 19-21

Dunayevich, E; Strakowski, S M; Sax, K W; Sorter, M T; Keck, P E; McElroy, S L; McConville, B J 1996. Personality disorders in first- and multiple-episode mania. Psychiatry research, 64 1, 69-75

Keck, P E; McElroy, S L 1996. Outcome in the pharmacologic treatment of bipolar disorder. Journal of clinical psychopharmacology, 16 2 Suppl 1, 15S-23S

Keck, P E; McElroy, S L; Strakowski, S M 1996. New developments in the pharmacologic treatment of schizoaffective disorder. The Journal of clinical psychiatry, 57 Suppl 9 , 41-8

Keck, P E; McElroy, S L; Strakowski, S M; Balistreri, T M; Kizer, D I; West, S A 1996. Factors associated with maintenance antipsychotic treatment of patients with bipolar disorder. The Journal of clinical psychiatry, 57 4, 147-51

Keck, P E; McElroy, S L; Strakowski, S M; Stanton, S P; Kizer, D L; Balistreri, T M; Bennett, J A; Tugrul, K C; West, S A 1996. Factors associated with pharmacologic noncompliance in patients with mania. The Journal of clinical psychiatry, 57 7, 292-7

Keck, P E; Nabulsi, A A; Taylor, J L; Henke, C J; Chmiel, J J; Stanton, S P; Bennett, J A 1996. A pharmacoeconomic model of divalproex vs. lithium in the acute and prophylactic treatment of bipolar I disorder. The Journal of clinical psychiatry, 57 5, 213-22

McElroy, S L; Keck, P E; Stanton, S P; Tugrul, K C; Bennett, J A; Strakowski, S M 1996. A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania. The Journal of clinical psychiatry, 57 4, 142-6

McElroy, S L; Keck, P E; Strakowski, S M 1996. Mania, psychosis, and antipsychotics. The Journal of clinical psychiatry, 57 Suppl 3 , 14-26; discussion 47

Sax, K W; Strakowski, S M; Keck, P E; Upadhyaya, V H; West, S A; McElroy, S L 1996. Relationships among negative, positive, and depressive symptoms in schizophrenia and psychotic depression. The British journal of psychiatry : the journal of mental science, 168 1, 68-71

Strakowski, S M; McElroy, S L; Keck, P E; West, S A 1996. Racial influence on diagnosis in psychotic mania. Journal of affective disorders, 39 2, 157-62

Strakowski, S M; McElroy, S L; Keck, P E; West, S A 1996. Suicidality among patients with mixed and manic bipolar disorder. The American journal of psychiatry, 153 5, 674-6

Strakowski, S M; Sax, K W; Setters, M J; Keck, P E 1996. Enhanced response to repeated d-amphetamine challenge: evidence for behavioral sensitization in humans. Biological psychiatry, 40 9, 872-80

West, S A; Sax, K W; Stanton, S P; Keck, P E; McElroy, S L; Strakowski, S M 1996. Differences in thyroid function studies in acutely manic adolescents with and without attention deficity hyperactivity disorder (ADHD). Psychopharmacology bulletin, 32 1, 63-6

West, S A; Strakowski, S M; Sax, K W; McElroy, S L; Keck, P E; McConville, B J 1996. Phenomenology and comorbidity of adolescents hospitalized for the treatment of acute mania. Biological psychiatry, 39 6, 458-60

Hawkins, J M; Archer, K J; Strakowski, S M; Keck, P E 1995. Somatic treatment of catatonia. International journal of psychiatry in medicine, 25 4, 345-69

Keck, P E; Wilson, D R; Strakowski, S M; McElroy, S L; Kizer, D L; Balistreri, T M; Holtman, H M; DePriest, M 1995. Clinical predictors of acute risperidone response in schizophrenia, schizoaffective disorder, and psychotic mood disorders. The Journal of clinical psychiatry, 56 10, 466-70

McElroy, S L; Keck, P E; Friedman, L M 1995. Minimizing and managing antidepressant side effects. The Journal of clinical psychiatry, 56 Suppl 2 , 49-55

McElroy, S L; Keck, P E; Phillips, K A 1995. Kleptomania, compulsive buying, and binge-eating disorder. The Journal of clinical psychiatry, 56 Suppl 4 , 14-26; discussion 27

Ram, A; Cao, Q; Keck, P E; Pope, H G; Otani, K; Addonizio, G; McElroy, S L; Kaneko, S; Redlichova, M; Gershon, E S 1995. Structural change in dopamine D2 receptor gene in a patient with neuroleptic malignant syndrome. American journal of medical genetics, 60 3, 228-30

Sax, K W; Strakowski, S M; McElroy, S L; Keck, P E; West, S A 1995. Attention and formal thought disorder in mixed and pure mania. Biological psychiatry, 37 6, 420-3

Strakowski, S M; Dunayevich, E; Keck, P E; McElroy, S L 1995. Affective state dependence of the Tridimensional Personality Questionnaire. Psychiatry research, 57 3, 209-14

West, S A; McElroy, S L; Strakowski, S M; Keck, P E; McConville, B J 1995. Attention deficit hyperactivity disorder in adolescent mania. The American journal of psychiatry, 152 2, 271-3

Dwight, M M; Keck, P E; Stanton, S P; Strakowski, S M; McElroy, S L 1994. Antidepressant activity and mania associated with risperidone treatment of schizoaffective disorder. Lancet, 344 8921, 554-5

Keck, P E; McElroy, S L; Strakowski, S M; West, S A 1994. Pharmacologic treatment of schizoaffective disorder. Psychopharmacology, 114 4, 529-38

Phillips, K A; McElroy, S L; Keck, P E; Hudson, J I; Pope, H G 1994. A comparison of delusional and nondelusional body dysmorphic disorder in 100 cases. Psychopharmacology bulletin, 30 2, 179-86

Stewart, W; Breslau, N; Keck, P E 1994. Comorbidity of migraine and panic disorder. Neurology, 44 10 Suppl 7, S23-7

Hudson, J I; Lipinski, J F; Keck, P E; Aizley, H G; Vuckovic, A; Zierk, K C; Pope, H G 1993. Polysomnographic characteristics of schizophrenia in comparison with mania and depression. Biological psychiatry, 34 3, 191-3

Keck, P E; McElroy, S L; Tugrul, K C; Bennett, J A 1993. Valproate oral loading in the treatment of acute mania. The Journal of clinical psychiatry, 54 8, 305-8

Keck, P E; Taylor, V E; Tugrul, K C; McElroy, S L; Bennett, J A 1993. Valproate treatment of panic disorder and lactate-induced panic attacks. Biological psychiatry, 33 7, 542-6

McElroy, S L; Keck, P E 1993. Treatment guidelines for valproate in bipolar and schizoaffective disorders. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 38 3 Suppl 2, S62-6

Hudson, J I; Goldenberg, D L; Pope, H G; Keck, P E; Schlesinger, L 1992. Comorbidity of fibromyalgia with medical and psychiatric disorders. The American journal of medicine, 92 4, 363-7

Hudson, J I; Pope, H G; Sullivan, L E; Waternaux, C M; Keck, P E; Broughton, R J 1992. Good sleep, bad sleep: a meta-analysis of polysomnographic measures in insomnia, depression, and narcolepsy. Biological psychiatry, 32 11, 958-75

Keck, P E; McElroy, S L 1992. Ratio of plasma fluoxetine to norfluoxetine concentrations and associated sedation. The Journal of clinical psychiatry, 53 4, 127-9

Keck, P E; McElroy, S L; Friedman, L M 1992. Valproate and carbamazepine in the treatment of panic and posttraumatic stress disorders, withdrawal states, and behavioral dyscontrol syndromes. Journal of clinical psychopharmacology, 12 1 Suppl, 36S-41S

Keck, P E; McElroy, S L; Nemeroff, C B 1992. Anticonvulsants in the treatment of bipolar disorder. The Journal of neuropsychiatry and clinical neurosciences, 4 4, 395-405

Keck, P E; McElroy, S L; Vuckovic, A; Friedman, L M 1992. Combined valproate and carbamazepine treatment of bipolar disorder. The Journal of neuropsychiatry and clinical neurosciences, 4 3, 319-22

McElroy, S L; Keck, P E; Pope, H G; Hudson, J I 1992. Valproate in the treatment of bipolar disorder: literature review and clinical guidelines. Journal of clinical psychopharmacology, 12 1 Suppl, 42S-52S

Cohen, B M; Keck, P E; Satlin, A; Cole, J O 1991. Prevalence and severity of akathisia in patients on clozapine. Biological psychiatry, 29 12, 1215-9

Keck, P E; Carter, W P; Nierenberg, A A; Cooper, T B; Potter, W Z; Rothschild, A J 1991. Acute cardiovascular effects of tranylcypromine: correlation with plasma drug, metabolite, norepinephrine, and MHPG levels. The Journal of clinical psychiatry, 52 6, 250-4

Keck, P E; Hudson, J I; Dorsey, C M; Campbell, P I 1991. Effect of fluoxetine on sleep. Biological psychiatry, 29 6, 618-9

Keck, P E; Pope, H G; McElroy, S L 1991. Declining frequency of neuroleptic malignant syndrome in a hospital population. The American journal of psychiatry, 148 7, 880-2

McElroy, S L; Dessain, E C; Pope, H G; Cole, J O; Keck, P E; Frankenberg, F R; Aizley, H G; O'Brien, S 1991. Clozapine in the treatment of psychotic mood disorders, schizoaffective disorder, and schizophrenia. The Journal of clinical psychiatry, 52 10, 411-4

McElroy, S L; Hudson, J I; Pope, H G; Keck, P E 1991. Kleptomania: clinical characteristics and associated psychopathology. Psychological medicine, 21 1, 93-108

McElroy, S L; Pope, H G; Hudson, J I; Keck, P E; White, K L 1991. Kleptomania: a report of 20 cases. The American journal of psychiatry, 148 5, 652-7

Pope, H G; Aizley, H G; Keck, P E; McElroy, S L 1991. Neuroleptic malignant syndrome: long-term follow-up of 20 cases. The Journal of clinical psychiatry, 52 5, 208-12

Pope, H G; McElroy, S L; Keck, P E; Hudson, J I 1991. Valproate in the treatment of acute mania. A placebo-controlled study. Archives of general psychiatry, 48 1, 62-8

Strakowski, S M; Hudson, J I; Keck, P E; Wilson, D R; Frankenburg, F R; Alpert, J E; Teschke, G C; Tohen, M 1991. Four cases of obstructive sleep apnea associated with treatment-resistant mania. The Journal of clinical psychiatry, 52 4, 156-8

Kando, J C; Keck, P E; Wood, P A 1990. Pergolide-induced hypotension. DICP : the annals of pharmacotherapy, 24 5, 543

Keck, P E; Seeler, D C; Pope, H G; McElroy, S L 1990. Porcine stress syndrome: an animal model for the neuroleptic malignant syndrome? Biological psychiatry, 28 1, 58-62

Vuckovic, A; Cohen, B M; Keck, P E; Shedlack, K J 1990. Neuroleptic dosage regimens in psychotic inpatients: a retrospective comparison. The Journal of clinical psychiatry, 51 3, 107-9

Hudson, J I; Pope, H G; Keck, P E; McElroy, S L 1989. Treatment of bulimia nervosa with trazodone: short-term response and long-term follow-up. Clinical neuropharmacology, 12 Suppl 1 , S38-46; Discussion S

Keck, P E; Pope, H G; Cohen, B M; McElroy, S L; Nierenberg, A A 1989. Risk factors for neuroleptic malignant syndrome. A case-control study. Archives of general psychiatry, 46 10, 914-8

Keck, P E; Pope, H G; Nierenberg, A A 1989. Autoinduction of hypertensive reactions by tranylcypromine? Journal of clinical psychopharmacology, 9 1, 48-51

Keck, P E; Sebastianelli, J; Pope, H G; McElroy, S L 1989. Frequency and presentation of neuroleptic malignant syndrome in a state psychiatric hospital. The Journal of clinical psychiatry, 50 9, 352-5

Pope, H G; Keck, P E; McElroy, S L; Hudson, J I 1989. A placebo-controlled study of trazodone in bulimia nervosa. Journal of clinical psychopharmacology, 9 4, 254-9

Pope, H G; McElroy, S L; Keck, P E; Hudson, J I 1989. Long-term pharmacotherapy of bulimia nervosa. Journal of clinical psychopharmacology, 9 5, 385-6

Cohen, B M; Buonanno, F; Keck, P E; Finklestein, S P; Benes, F M 1988. Comparison of MRI and CT scans in a group of psychiatric patients. The American journal of psychiatry, 145 9, 1084-8

McElroy, S L; Keck, P E; Pope, H G; Hudson, J I 1988. Valproate in the treatment of rapid-cycling bipolar disorder. Journal of clinical psychopharmacology, 8 4, 275-9

Keck, P E; Pope, H G; McElroy, S L 1987. Frequency and presentation of neuroleptic malignant syndrome: a prospective study. The American journal of psychiatry, 144 10, 1344-6

Keck, P E; Lipinski, J F; White, K 1986. An inverse relationship between mania and obsessive-compulsive disorder: a case report. Journal of clinical psychopharmacology, 6 2, 123-4

Pope, H G; Keck, P E; McElroy, S L 1986. Frequency and presentation of neuroleptic malignant syndrome in a large psychiatric hospital. The American journal of psychiatry, 143 10, 1227-33

Bermudes, Richard A; Keck, Paul E; Welge, Jeffrey A . The prevalence of the metabolic syndrome in psychiatric inpatients with primary psychotic and mood disorders. Psychosomatics, 47 6, 491-7

Dwight, M M; Arnold, L M; O'Brien, H; Metzger, R; Morris-Park, E; Keck, P E . An open clinical trial of venlafaxine treatment of fibromyalgia. Psychosomatics, 39 1, 14-7

Galli, V; McElroy, S L; Soutullo, C A; Kizer, D; Raute, N; Keck, P E; McConville, B J . The psychiatric diagnoses of twenty-two adolescents who have sexually molested other children. Comprehensive psychiatry, 40 2, 85-8

Keck, P E; Pope, H G; Hudson, J I; McElroy, S L; Yurgelun-Todd, D; Hundert, E M . A controlled study of phenomenology and family history in outpatients with bulimia nervosa. Comprehensive psychiatry, 31 4, 275-83

Keck, Paul E; Hsu, Hai-An; Papadakis, Kelly; Russo, John . Memantine efficacy and safety in patients with acute mania associated with bipolar I disorder: a pilot evaluation. Clinical neuropharmacology, 32 4, 199-204

Keck, Paul E; McElroy, Susan L; Havens, Jennifer Rochussen; Altshuler, Lori L; Nolen, Willem A; Frye, Mark A; Suppes, Trisha; Denicoff, Kirk D; Kupka, Ralph; Leverich, Gabrielle S; Rush, A John; Post, Robert M . Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness. Comprehensive psychiatry, 44 4, 263-9

McElroy, S L; Pope, H G; Keck, P E; Hudson, J I; Phillips, K A; Strakowski, S M . Are impulse-control disorders related to bipolar disorder? Comprehensive psychiatry, 37 4, 229-40

McElroy, S L; Strakowski, S M; Keck, P E; Tugrul, K L; West, S A; Lonczak, H S . Differences and similarities in mixed and pure mania. Comprehensive psychiatry, 36 3, 187-94

Pope, H G; McElroy, S L; Satlin, A; Hudson, J I; Keck, P E; Kalish, R . Head injury, bipolar disorder, and response to valproate. Comprehensive psychiatry, 29 1, 34-8

Shapira, N A; Goldsmith, T D; Keck, P E; Khosla, U M; McElroy, S L . Psychiatric features of individuals with problematic internet use. Journal of affective disorders, 57 1-3, 267-72

Strakowski, S M; Keck, P E; McElroy, S L; Lonczak, H S; West, S A . Chronology of comorbid and principal syndromes in first-episode psychosis. Comprehensive psychiatry, 36 2, 106-12

White, K; Keck, P E; Lipinski, J . Serotonin-uptake inhibitors in obsessive-compulsive disorder: a case report. Comprehensive psychiatry, 27 3, 211-4