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Department of

Psychiatry and Behavioral Neuroscience

Photo of  Cal Adler, MD

Cal Adler, MD

Professor of Psychiatry and Behavioral Neuroscience; Vice Chair of Research; Co-Director of the Division of Bipolar Disorders Research; and Director of the Center for Imaging Research

Education/Credentials
  • Bachelor's Degree: Pennsylvania State University
  • Medical Degree: Jefferson Medical College of the Thomas Jefferson University
  • Residency: Georgetown University Medical Center
  • Fellowship: National Institute of Mental Health

Contact Information
  • Stenson Building
  • Suite 3200
  • 260 Stetson Street
  • Cincinnati, Ohio 45219
  • Office 513-558-7700
  • Email caleb.adler@uc.edu

Peer Reviewed Publications

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Dudley, Jonathan; DelBello, Melissa P; Weber, Wade A; Adler, Caleb M; Strakowski, Stephen M; Lee, Jing-Huei 2016. Tissue-dependent cerebral energy metabolism in adolescents with bipolar disorder. Journal of affective disorders, 191 , 248-55

Davis, Andrew K; DelBello, Melissa P; Eliassen, James; Welge, Jeffrey; Blom, Thomas J; Fleck, David E; Weber, Wade A; Jarvis, Kelly B; Rummelhoff, Emily; Strakowski, Stephen M; Adler, Caleb M 2015. Neurofunctional effects of quetiapine in patients with bipolar mania. Bipolar disorders, 17 4, 444-9

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Blom, Thomas J; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M 2015. First-episode bipolar disorder is associated with erythrocyte membrane docosahexaenoic acid deficits: Dissociation from clinical response to lithium or quetiapine. Psychiatry research, 230 2, 447-53

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Blom, Thomas J; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P 2015. Adolescents with or at ultra-high risk for bipolar disorder exhibit erythrocyte docosahexaenoic acid and eicosapentaenoic acid deficits: a candidate prodromal risk biomarker. Early intervention in psychiatry, ,

Wehry, Anna M; McNamara, Robert K; Adler, Caleb M; Eliassen, James C; Croarkin, Paul; Cerullo, Michael A; DelBello, Melissa P; Strawn, Jeffrey R 2015. Neurostructural impact of co-occurring anxiety in pediatric patients with major depressive disorder: a voxel-based morphometry study. Journal of affective disorders, 171 , 54-9

Bitter, Samantha M; Adler, Caleb M; Eliassen, James C; Weber, Wade A; Welge, Jeffrey A; Burciaga, Joaquin; Shear, Paula K; Strakowski, Stephen M; DelBello, Melissa P 2014. Neurofunctional changes in adolescent cannabis users with and without bipolar disorder. Addiction (Abingdon, England), 109 11, 1901-9

Bitter, Samantha M; Weber, Wade A; Chu, Wen-Jang; Adler, Caleb M; Eliassen, James C; Strakowski, Stephen M; DelBello, Melissa P 2014. N-acetyl aspartate levels in adolescents with bipolar and/or cannabis use disorders. Journal of dual diagnosis, 10 1, 39-43

Cerullo, Michael A; Eliassen, James C; Smith, Christopher T; Fleck, David E; Nelson, Erik B; Strawn, Jeffrey R; Lamy, Martine; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2014. Bipolar I disorder and major depressive disorder show similar brain activation during depression. Bipolar disorders, 16 7, 703-12

Dawson, Erica L; Shear, Paula K; Howe, Steven R; Adler, Caleb M; DelBello, Melissa P; Fleck, David E; Strakowski, Stephen M 2014. Impulsivity predicts time to reach euthymia in adults with bipolar disorder. Bipolar disorders, 16 8, 846-56

McNamara, Robert K; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Chu, Wen-Jang; Weber, Wade A; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; DelBello, Melissa P 2014. Effects of fish oil supplementation on prefrontal metabolite concentrations in adolescents with major depressive disorder: A preliminary (1)H MRS study. Nutritional neuroscience, ,

Schneider, Marguerite Reid; Klein, Christina C; Weber, Wade; Bitter, Samantha M; Elliott, Kimberly B; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2014. The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder. Psychiatry research, 223 3, 268-70

Stephens, Jacob R; Heffner, Jaimee L; Adler, Caleb M; Blom, Thomas J; Anthenelli, Robert M; Fleck, David E; Welge, Jeffrey A; Strakowski, Stephen M; DelBello, Melissa P 2014. Risk and protective factors associated with substance use disorders in adolescents with first-episode mania. Journal of the American Academy of Child and Adolescent Psychiatry, 53 7, 771-9

Strawn, Jeffrey R; Adler, Caleb M; McNamara, Robert K; Welge, Jeffrey A; Bitter, Samantha M; Mills, Neil P; Barzman, Drew H; Cerullo, Michael A; Chang, Kiki D; Strakowski, Stephen M; DelBello, Melissa P 2014. Antidepressant tolerability in anxious and depressed youth at high risk for bipolar disorder: a prospective naturalistic treatment study. Bipolar disorders, 16 5, 523-30

Strawn, Jeffrey R; John Wegman, C; Dominick, Kelli C; Swartz, Max S; Wehry, Anna M; Patino, Luis R; Strakowski, Stephen M; Adler, Caleb M; Eliassen, James C; DelBello, Melissa P 2014. Cortical surface anatomy in pediatric patients with generalized anxiety disorder. Journal of anxiety disorders, 28 7, 717-23

Adler, Caleb M; DelBello, Melissa P; Weber, Wade A; Jarvis, Kelly B; Welge, Jeffrey; Chu, Wen-Jang; Rummelhoff, Emily; Kim, Mi-Jung; Lee, Jing-Huei; Strakowski, Stephen M 2013. Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study. Journal of clinical psychopharmacology, 33 4, 528-32

Chu, Wen-Jang; Delbello, Melissa P; Jarvis, Kelly B; Norris, Mathew M; Kim, Mi-Jung; Weber, Wade; Lee, Jing-Huei; Strakowski, Stephen M; Adler, Caleb M 2013. Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder. Psychiatry research, 213 3, 230-4

Heffner, Jaimee L; Anthenelli, Robert M; Adler, Caleb M; Strakowski, Stephen M; Beavers, Jennifer; DelBello, Melissa P 2013. Prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders. Psychiatry research, 210 3, 857-62

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Weber, Wade; Chu, Wen-Jang; Strakowski, Stephen M; Adler, Caleb M; Delbello, Melissa P 2013. Low docosahexaenoic acid status is associated with reduced indices in cortical integrity in the anterior cingulate of healthy male children: a 1H MRS Study. Nutritional neuroscience, 16 4, 183-90

Patino, Luis R; Adler, Caleb M; Mills, Neil P; Strakowski, Stephen M; Fleck, David E; Welge, Jeffrey A; DelBello, Melissa P 2013. Conflict monitoring and adaptation in individuals at familial risk for developing bipolar disorder. Bipolar disorders, 15 3, 264-71

Southammakosane, C; Danielyan, A; Welge, J A; Blom, T J; Adler, C M; Chang, K D; Howe, M; DelBello, M P 2013. Characteristics of the child behavior checklist in adolescents with depression associated with bipolar disorder. Journal of affective disorders, 145 3, 405-8

Strakowski, Stephen M; Adler, Caleb M; Delbello, Melissa P 2013. Is depression simply a nonspecific response to brain injury? Current psychiatry reports, 15 9, 386

Strawn, Jeffrey R; Chu, Wen-Jang; Whitsel, Rachel M; Weber, Wade A; Norris, Matthew M; Adler, Caleb M; Eliassen, James C; Phan, K Luan; Strakowski, Stephen M; DelBello, Melissa P 2013. A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder. Neuropsychobiology, 67 4, 224-9

Strawn, Jeffrey R; Wehry, Anna M; Chu, Wen-Jang; Adler, Caleb M; Eliassen, James C; Cerullo, Michael A; Strakowski, Stephen M; Delbello, Melissa P 2013. Neuroanatomic abnormalities in adolescents with generalized anxiety disorder: a voxel-based morphometry study. Depression and anxiety, 30 9, 842-8

Weber, Wade A; Dudley, Jonathan; Lee, Jing-Huei; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2013. A pilot study of alterations in high energy phosphoryl compounds and intracellular pH in unmedicated adolescents with bipolar disorder. Journal of affective disorders, 150 3, 1109-13

Cerullo, Michael A; Fleck, David E; Eliassen, James C; Smith, Matt S; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2012. A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states. Bipolar disorders, 14 2, 175-84

Fleck, D E; Eliassen, J C; Durling, M; Lamy, M; Adler, C M; DelBello, M P; Shear, P K; Cerullo, M A; Lee, J-H; Strakowski, S M 2012. Functional MRI of sustained attention in bipolar mania. Molecular psychiatry, 17 3, 325-36

Heffner, Jaimee L; DelBello, Melissa P; Anthenelli, Robert M; Fleck, David E; Adler, Caleb M; Strakowski, Stephen M 2012. Cigarette smoking and its relationship to mood disorder symptoms and co-occurring alcohol and cannabis use disorders following first hospitalization for bipolar disorder. Bipolar disorders, 14 1, 99-108

Heffner, Jaimee L; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Strakowski, Stephen M 2012. Unplanned pregnancies in adolescents with bipolar disorder. The American journal of psychiatry, 169 12, 1319

Heffner, Jaimee L; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2012. Cigarette smoking and impulsivity in bipolar disorder. Bipolar disorders, 14 7, 735-42

Schneider, Marguerite Reid; Adler, Caleb M; Whitsel, Rachel; Weber, Wade; Mills, Neil P; Bitter, Samantha M; Eliassen, James; Strakowski, Stephen M; DelBello, Melissa P 2012. The effects of ziprasidone on prefrontal and amygdalar activation in manic youth with bipolar disorder. The Israel journal of psychiatry and related sciences, 49 2, 112-20

Schneider, Marguerite Reid; DelBello, Melissa P; McNamara, Robert K; Strakowski, Stephen M; Adler, Caleb M 2012. Neuroprogression in bipolar disorder. Bipolar disorders, 14 4, 356-74

Strakowski, Stephen M; Adler, Caleb M; Almeida, Jorge; Altshuler, Lori L; Blumberg, Hilary P; Chang, Kiki D; DelBello, Melissa P; Frangou, Sophia; McIntosh, Andrew; Phillips, Mary L; Sussman, Jessika E; Townsend, Jennifer D 2012. The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar disorders, 14 4, 313-25

Strawn, Jeffrey R; Patel, Nick C; Chu, Wen-Jang; Lee, Jing-Huei; Adler, Caleb M; Kim, Mi Jung; Bryan, Holly S; Alfieri, David C; Welge, Jeffrey A; Blom, Thomas J; Nandagopal, Jayasree J; Strakowski, Stephen M; DelBello, Melissa P 2012. Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study. Journal of the American Academy of Child and Adolescent Psychiatry, 51 6, 642-51

Bitter, Samantha M; Mills, Neil P; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P 2011. Progression of amygdala volumetric abnormalities in adolescents after their first manic episode. Journal of the American Academy of Child and Adolescent Psychiatry, 50 10, 1017-26

Fleck, David E; Kotwal, Renu; Eliassen, James C; Lamy, Martine; Delbello, Melissa P; Adler, Caleb M; Durling, Michelle; Cerullo, Michael A; Strakowski, Stephen M 2011. Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder. Journal of affective disorders, 133 1-2, 333-9

Lisy, Megan E; Jarvis, Kelly B; DelBello, Melissa P; Mills, Neil P; Weber, Wade A; Fleck, David; Strakowski, Stephen M; Adler, Caleb M 2011. Progressive neurostructural changes in adolescent and adult patients with bipolar disorder. Bipolar disorders, 13 4, 396-405

Macfadden, Wayne; Adler, Caleb M; Turkoz, Ibrahim; Haskins, John T; Turner, Norris; Alphs, Larry 2011. Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms. BMC psychiatry, 11 , 171

Nandagopal, Jayasree J; Fleck, David E; Adler, Caleb M; Mills, Neil P; Strakowski, Stephen M; DelBello, Melissa P 2011. Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale. Journal of child and adolescent psychopharmacology, 21 5, 465-8

Strakowski, Stephen M; Eliassen, James C; Lamy, Martine; Cerullo, Michael A; Allendorfer, Jane B; Madore, Michelle; Lee, Jing-Huei; Welge, Jeffrey A; DelBello, Melissa P; Fleck, David E; Adler, Caleb M 2011. Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway. Biological psychiatry, 69 4, 381-8

McNamara, Robert K; Able, Jessica; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Eliassen, James C; Alfieri, David; Weber, Wade; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M; Adler, Caleb M 2010. Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study. The American journal of clinical nutrition, 91 4, 1060-7

McNamara, Robert K; Able, Jessica; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Eliassen, James C; Alfieri, David; Weber, Wade; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M; Adler, Caleb M 2010. Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study. The American journal of clinical nutrition, 91 4, 1060-7

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; Kotwal, Renu; Arndt, Stephan 2010. Impulsivity across the course of bipolar disorder. Bipolar disorders, 12 3, 285-97

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; Kotwal, Renu; Arndt, Stephan 2010. Impulsivity across the course of bipolar disorder. Bipolar disorders, 12 3, 285-97

Strawn, Jeffrey R; Adler, Caleb M; Fleck, David E; Hanseman, Dennis; Maue, Danielle K; Bitter, Samantha; Kraft, Elizabeth M; Geracioti, Thomas D; Strakowski, Stephen M; DelBello, Melissa P 2010. Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder. Early intervention in psychiatry, 4 2, 169-73

Strawn, Jeffrey R; Adler, Caleb M; Fleck, David E; Hanseman, Dennis; Maue, Danielle K; Bitter, Samantha; Kraft, Elizabeth M; Geracioti, Thomas D; Strakowski, Stephen M; DelBello, Melissa P 2010. Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder. Early intervention in psychiatry, 4 2, 169-73

Cerullo, Michael A; Adler, Caleb M; Delbello, Melissa P; Strakowski, Stephen M 2009. The functional neuroanatomy of bipolar disorder. International review of psychiatry (Abingdon, England), 21 4, 314-22

Cerullo, Michael A; Adler, Caleb M; Delbello, Melissa P; Strakowski, Stephen M 2009. The functional neuroanatomy of bipolar disorder. International review of psychiatry (Abingdon, England), 21 4, 314-22

Cerullo, Michael A; Adler, Caleb M; Lamy, Martine; Eliassen, James C; Fleck, David E; Strakowski, Stephen M; DelBello, Melissa P 2009. Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders. Early intervention in psychiatry, 3 3, 189-97

DelBello, Melissa P; Chang, Kiki; Welge, Jeffrey A; Adler, Caleb M; Rana, Manasi; Howe, Meghan; Bryan, Holly; Vogel, Daniel; Sampang, Suzanne; Delgado, Sergio V; Sorter, Michael; Strakowski, Stephen M 2009. A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar disorders, 11 5, 483-93

DelBello, Melissa P; Chang, Kiki; Welge, Jeffrey A; Adler, Caleb M; Rana, Manasi; Howe, Meghan; Bryan, Holly; Vogel, Daniel; Sampang, Suzanne; Delgado, Sergio V; Sorter, Michael; Strakowski, Stephen M 2009. A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar disorders, 11 5, 483-93

Epstein, J N; Delbello, M P; Adler, C M; Altaye, M; Kramer, M; Mills, N P; Strakowski, S M; Holland, S 2009. Differential patterns of brain activation over time in adolescents with and without attention deficit hyperactivity disorder (ADHD) during performance of a sustained attention task. Neuropediatrics, 40 1, 1-5

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; McElroy, Susan L; Keck, Paul E; Moss, Quinton; Cerullo, Michael A; Kotwal, Renu; Arndt, Stephan 2009. Characterizing impulsivity in mania. Bipolar disorders, 11 1, 41-51

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; McElroy, Susan L; Keck, Paul E; Moss, Quinton; Cerullo, Michael A; Kotwal, Renu; Arndt, Stephan 2009. Characterizing impulsivity in mania. Bipolar disorders, 11 1, 41-51

Cecil, Kim M; Brubaker, Christopher J; Adler, Caleb M; Dietrich, Kim N; Altaye, Mekibib; Egelhoff, John C; Wessel, Stephanie; Elangovan, Ilayaraja; Hornung, Richard; Jarvis, Kelly; Lanphear, Bruce P 2008. Decreased brain volume in adults with childhood lead exposure. PLoS medicine, 5 5, e112

Fleck, David E; Nandagopal, Jayasree; Cerullo, Michael A; Eliassen, James C; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2008. Morphometric magnetic resonance imaging in psychiatry. Topics in magnetic resonance imaging : TMRI, 19 2, 131-42

Fleck, David E; Nandagopal, Jayasree; Cerullo, Michael A; Eliassen, James C; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2008. Morphometric magnetic resonance imaging in psychiatry. Topics in magnetic resonance imaging : TMRI, 19 2, 131-42

Jarvis, Kelly; DelBello, Melissa P; Mills, Neil; Elman, Igor; Strakowski, Stephen M; Adler, Caleb M 2008. Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders. Journal of child and adolescent psychopharmacology, 18 6, 557-63

Jarvis, Kelly; DelBello, Melissa P; Mills, Neil; Elman, Igor; Strakowski, Stephen M; Adler, Caleb M 2008. Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders. Journal of child and adolescent psychopharmacology, 18 6, 557-63

Patel, Nick C; Cecil, Kim M; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2008. Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex. Journal of child and adolescent psychopharmacology, 18 6, 623-7

Patel, Nick C; Cecil, Kim M; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2008. Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex. Journal of child and adolescent psychopharmacology, 18 6, 623-7

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Stanford, Kevin E; Adler, Caleb M; Strakowski, Stephen M 2008. Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium. Journal of child and adolescent psychopharmacology, 18 2, 132-9

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Stanford, Kevin E; Adler, Caleb M; Strakowski, Stephen M 2008. Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium. Journal of child and adolescent psychopharmacology, 18 2, 132-9

Pfeifer, Jonathan C; Welge, Jeffrey; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2008. Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 47 11, 1289-98

Pfeifer, Jonathan C; Welge, Jeffrey; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2008. Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 47 11, 1289-98

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M 2008. Neuroanatomical characterization of child offspring of bipolar parents. Journal of the American Academy of Child and Adolescent Psychiatry, 47 5, 526-31

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M 2008. Neuroanatomical characterization of child offspring of bipolar parents. Journal of the American Academy of Child and Adolescent Psychiatry, 47 5, 526-31

Strakowski, Stephen M; Adler, Caleb M; Cerullo, Michael A; Eliassen, James C; Lamy, Martine; Fleck, David E; Lee, Jing-Huei; Delbello, Melissa P 2008. MRI brain activation in first-episode bipolar mania during a response inhibition task. Early intervention in psychiatry, 2 4, 225-233

Strakowski, Stephen M; Adler, Caleb M; Cerullo, Michael A; Eliassen, James C; Lamy, Martine; Fleck, David E; Lee, Jing-Huei; DelBello, Melissa P 2008. Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task. Early intervention in psychiatry, 2 4, 225-33

Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P 2008. Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine. Journal of child and adolescent psychopharmacology, 18 1, 116-8

Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P 2008. Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine. Journal of child and adolescent psychopharmacology, 18 1, 116-8

Adams, John; Adler, Caleb M; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M 2007. Evidence of anterior temporal atrophy in college-level soccer players. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 17 4, 304-6

Adams, John; Adler, Caleb M; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M 2007. Evidence of anterior temporal atrophy in college-level soccer players. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 17 4, 304-6

Adler, Caleb M; DelBello, Melissa P; Jarvis, Kelly; Levine, Ari; Adams, John; Strakowski, Stephen M 2007. Voxel-based study of structural changes in first-episode patients with bipolar disorder. Biological psychiatry, 61 6, 776-81

Adler, Caleb M; DelBello, Melissa P; Jarvis, Kelly; Levine, Ari; Adams, John; Strakowski, Stephen M 2007. Voxel-based study of structural changes in first-episode patients with bipolar disorder. Biological psychiatry, 61 6, 776-81

Adler, Caleb M; Fleck, David E; Brecher, Martin; Strakowski, Stephen M 2007. Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder. Journal of affective disorders, 100 Suppl 1 , S15-22

Cerullo, Michael A; Adler, Caleb M; Strakowski, Stephen M; Eliassen, James C; Nasrallah, Henry A; Nasrallah, Amelia T 2007. Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI study. Schizophrenia research, 97 1-3, 294-6

DelBello, Melissa P; Adler, Caleb M; Whitsel, Rachel M; Stanford, Kevin E; Strakowski, Stephen M 2007. A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder. The Journal of clinical psychiatry, 68 5, 789-95

DelBello, Melissa P; Adler, Caleb M; Whitsel, Rachel M; Stanford, Kevin E; Strakowski, Stephen M 2007. A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder. The Journal of clinical psychiatry, 68 5, 789-95

DelBello, Melissa P; Hanseman, Dennis; Adler, Caleb M; Fleck, David E; Strakowski, Stephen M 2007. Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode. The American journal of psychiatry, 164 4, 582-90

DelBello, Melissa P; Hanseman, Dennis; Adler, Caleb M; Fleck, David E; Strakowski, Stephen M 2007. Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode. The American journal of psychiatry, 164 4, 582-90

DiFrancesco, Mark W; Holland, Scott K; Ris, M Douglas; Adler, Caleb M; Nelson, Shannen; DelBello, Melissa P; Altaye, Mekibib; Brunner, Hermine I 2007. Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study. Arthritis and rheumatism, 56 12, 4151-63

DiFrancesco, Mark W; Holland, Scott K; Ris, M Douglas; Adler, Caleb M; Nelson, Shannen; DelBello, Melissa P; Altaye, Mekibib; Brunner, Hermine I 2007. Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study. Arthritis and rheumatism, 56 12, 4151-63

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M 2007. Acute dystonia associated with aripiprazole in a child. Journal of the American Academy of Child and Adolescent Psychiatry, 46 3, 306-7

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M 2007. Acute dystonia associated with aripiprazole in a child. Journal of the American Academy of Child and Adolescent Psychiatry, 46 3, 306-7

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2007. Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania. Archives of general psychiatry, 64 1, 57-64

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2007. Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania. Archives of general psychiatry, 64 1, 57-64

Strakowski, Stephen M; Tsai, Shang-Ying; Delbello, Melissa P; Chen, Chiao-Chicy; Fleck, David E; Adler, Caleb M; Arndt, Stephan; Amicone, Jennifer 2007. Outcome following a first manic episode: cross-national US and Taiwan comparison. Bipolar disorders, 9 8, 820-7

Strakowski, Stephen M; Tsai, Shang-Ying; Delbello, Melissa P; Chen, Chiao-Chicy; Fleck, David E; Adler, Caleb M; Arndt, Stephan; Amicone, Jennifer 2007. Outcome following a first manic episode: cross-national US and Taiwan comparison. Bipolar disorders, 9 8, 820-7

Adler, Caleb M; Adams, John; DelBello, Melissa P; Holland, Scott K; Schmithorst, Vince; Levine, Ari; Jarvis, Kelly; Strakowski, Stephen M 2006. Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study. The American journal of psychiatry, 163 2, 322-4

Adler, Caleb M; Adams, John; DelBello, Melissa P; Holland, Scott K; Schmithorst, Vince; Levine, Ari; Jarvis, Kelly; Strakowski, Stephen M 2006. Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study. The American journal of psychiatry, 163 2, 322-4

Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M 2006. Brain network dysfunction in bipolar disorder. CNS spectrums, 11 4, 312-20; quiz 323-4

Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M 2006. Brain network dysfunction in bipolar disorder. CNS spectrums, 11 4, 312-20; quiz 323-4

Barzman, Drew H; DelBello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M 2006. The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s). Journal of child and adolescent psychopharmacology, 16 6, 665-70

Barzman, Drew H; DelBello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M 2006. The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s). Journal of child and adolescent psychopharmacology, 16 6, 665-70

DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2006. The neurophysiology of childhood and adolescent bipolar disorder. CNS spectrums, 11 4, 298-311

DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2006. The neurophysiology of childhood and adolescent bipolar disorder. CNS spectrums, 11 4, 298-311

DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Daniels, John P; Strakowski, Stephen M 2006. Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 31 6, 1264-73

DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Daniels, John P; Strakowski, Stephen M 2006. Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 31 6, 1264-73

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M 2006. A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 305-13

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M 2006. A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 305-13

Patel, Nick C; DelBello, Melissa P; Bryan, Holly S; Adler, Caleb M; Kowatch, Robert A; Stanford, Kevin; Strakowski, Stephen M 2006. Open-label lithium for the treatment of adolescents with bipolar depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 289-97

Patel, Nick C; DelBello, Melissa P; Bryan, Holly S; Adler, Caleb M; Kowatch, Robert A; Stanford, Kevin; Strakowski, Stephen M 2006. Open-label lithium for the treatment of adolescents with bipolar depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45 3, 289-97

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Bryan, Holly S; Stanford, Kevin E; Strakowski, Stephen M 2006. Lithium treatment effects on Myo-inositol in adolescents with bipolar depression. Biological psychiatry, 60 9, 998-1004

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Bryan, Holly S; Stanford, Kevin E; Strakowski, Stephen M 2006. Lithium treatment effects on Myo-inositol in adolescents with bipolar depression. Biological psychiatry, 60 9, 998-1004

Weinstein, Shannon K; Adler, Caleb M; Strakowski, Stephen M 2006. Ziprasidone-induced acute dystonic reactions in patients with bipolar disorder. The Journal of clinical psychiatry, 67 2, 327-8

Adler, Caleb M; Delbello, Melissa P; Mills, Neil P; Schmithorst, Vince; Holland, Scott; Strakowski, Stephen M 2005. Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task. Bipolar disorders, 7 6, 577-88

Adler, Caleb M; Delbello, Melissa P; Mills, Neil P; Schmithorst, Vince; Holland, Scott; Strakowski, Stephen M 2005. Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task. Bipolar disorders, 7 6, 577-88

Adler, Caleb M; Levine, Ari D; DelBello, Melissa P; Strakowski, Stephen M 2005. Changes in gray matter volume in patients with bipolar disorder. Biological psychiatry, 58 2, 151-7

Adler, Caleb M; Levine, Ari D; DelBello, Melissa P; Strakowski, Stephen M 2005. Changes in gray matter volume in patients with bipolar disorder. Biological psychiatry, 58 2, 151-7

Mills, Neil P; Delbello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2005. MRI analysis of cerebellar vermal abnormalities in bipolar disorder. The American journal of psychiatry, 162 8, 1530-2

Mills, Neil P; Delbello, Melissa P; Adler, Caleb M; Strakowski, Stephen M 2005. MRI analysis of cerebellar vermal abnormalities in bipolar disorder. The American journal of psychiatry, 162 8, 1530-2

Strakowski, S M; Delbello, M P; Adler, C M 2005. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Molecular psychiatry, 10 1, 105-16

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil P; DelBello, Melissa P; Eliassen, James C 2005. Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task. The American journal of psychiatry, 162 9, 1697-705

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil P; DelBello, Melissa P; Eliassen, James C 2005. Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task. The American journal of psychiatry, 162 9, 1697-705

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2005. Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. Archives of general psychiatry, 62 8, 851-8

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer 2005. Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. Archives of general psychiatry, 62 8, 851-8

Adler, Caleb M; Holland, Scott K; Schmithorst, Vince; Tuchfarber, Michael J; Strakowski, Stephen M 2004. Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task. Bipolar disorders, 6 6, 540-9

Adler, Caleb M; Holland, Scott K; Schmithorst, Vince; Wilke, Marko; Weiss, Kenneth L; Pan, Hai; Strakowski, Stephen M 2004. Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study. Bipolar disorders, 6 3, 197-203

DelBello, Melissa P; Adler, Caleb M; Amicone, Jennifer; Mills, Neil P; Shear, Paula K; Warner, Juliet; Strakowski, Stephen M 2004. Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder. Journal of affective disorders, 82 Suppl 1 , S79-88

DelBello, Melissa P; Adler, Caleb M; Amicone, Jennifer; Mills, Neil P; Shear, Paula K; Warner, Juliet; Strakowski, Stephen M 2004. Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder. Journal of affective disorders, 82 Suppl 1 , S79-88

Hopper, J W; Karlsgodt, K H; Adler, C M; Macklin, E A; Lukas, S E; Elman, I 2004. Effects of acute cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence. Human psychopharmacology, 19 7, 511-6

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil; DelBello, Melissa P 2004. A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 29 9, 1734-40

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil; DelBello, Melissa P 2004. A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 29 9, 1734-40

Adler, Caleb M; Strakowski, Stephen M 2003. Boundaries of schizophrenia. The Psychiatric clinics of North America, 26 1, 1-23

Strakowski, Stephen M; Del Bello, Melissa P; Adler, Caleb M; Keck, Paul E 2003. Atypical antipsychotics in the treatment of bipolar disorder. Expert opinion on pharmacotherapy, 4 5, 751-60

Adler, Caleb M; Malhotra, Anil K; Elman, Igor; Pickar, David; Breier, Alan 2002. Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 26 3, 295-300

Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2002. Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? Bipolar disorders, 4 2, 80-8

Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P 2002. Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? Bipolar disorders, 4 2, 80-8

Strakowski, Stephen M; DelBello, Melissa P; Zimmerman, Molly E; Getz, Glen E; Mills, Neil P; Ret, Jennifer; Shear, Paula; Adler, Caleb M 2002. Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder. The American journal of psychiatry, 159 11, 1841-7

Strakowski, Stephen M; DelBello, Melissa P; Zimmerman, Molly E; Getz, Glen E; Mills, Neil P; Ret, Jennifer; Shear, Paula; Adler, Caleb M 2002. Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder. The American journal of psychiatry, 159 11, 1841-7

Adler, C M; Holland, S K; Enseleit, S; Strakowski, S M 2001. Age-related changes in regional activation during working memory in young adults: an fMRI study. Synapse (New York, N.Y.), 42 4, 252-7

Adler, C M; Sax, K W; Holland, S K; Schmithorst, V; Rosenberg, L; Strakowski, S M 2001. Changes in neuronal activation with increasing attention demand in healthy volunteers: an fMRI study. Synapse (New York, N.Y.), 42 4, 266-72

Elman, I; Goldstein, D S; Adler, C M; Shoaf, S E; Breier, A 2001. Inverse relationship between plasma epinephrine and testosterone levels during acute glucoprivation in healthy men. Life sciences, 68 16, 1889-98

Strakowski, S M; DelBello, M P; Adler, C M 2001. Comparative efficacy and tolerability of drug treatments for bipolar disorder. CNS drugs, 15 9, 701-18

Strakowski, S M; Sax, K W; Rosenberg, H L; DelBello, M P; Adler, C M 2001. Human response to repeated low-dose d-amphetamine: evidence for behavioral enhancement and tolerance. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 25 4, 548-54

Adler, C M; Elman, I; Weisenfeld, N; Kestler, L; Pickar, D; Breier, A 2000. Effects of acute metabolic stress on striatal dopamine release in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 22 5, 545-50

Adler, C M; Malhotra, A K; Elman, I; Goldberg, T; Egan, M; Pickar, D; Breier, A 1999. Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia. The American journal of psychiatry, 156 10, 1646-9

Breier, A F; Malhotra, A K; Su, T P; Pinals, D A; Elman, I; Adler, C M; Lafargue, R T; Clifton, A; Pickar, D 1999. Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response. The American journal of psychiatry, 156 2, 294-8

Breier, A; Su, T P; Malhotra, A K; Elman, I; Adler, C M; Weisenfeld, N I; Pickar, D 1999. Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 20 4, 340-5

Elman, I; Goldstein, D S; Eisenhofer, G; Folio, J; Malhotra, A K; Adler, C M; Pickar, D; Breier, A 1999. Mechanism of peripheral noradrenergic stimulation by clozapine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 20 1, 29-34

Elman, I; Sokoloff, L; Adler, C M; Weisenfeld, N; Breier, A 1999. The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers. Brain research, 815 2, 243-9

Adler, C M; Goldberg, T E; Malhotra, A K; Pickar, D; Breier, A 1998. Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biological psychiatry, 43 11, 811-6

Breier, A; Adler, C M; Weisenfeld, N; Su, T P; Elman, I; Picken, L; Malhotra, A K; Pickar, D 1998. Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach. Synapse (New York, N.Y.), 29 2, 142-7

Elman, I; Adler, C M; Malhotra, A K; Bir, C; Pickar, D; Breier, A 1998. Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia. The American journal of psychiatry, 155 7, 979-81

Hillhouse, J J; Adler, C M 1997. Investigating stress effect patterns in hospital staff nurses: results of a cluster analysis. Social science & medicine (1982), 45 12, 1781-8

Hillhouse, J J; Adler, C M; Drinnon, J; Turrisi, R 1997. Application of Azjen's theory of planned behavior to predict sunbathing, tanning salon use, and sunscreen use intentions and behaviors. Journal of behavioral medicine, 20 4, 365-78

Malhotra, A K; Adler, C M; Kennison, S D; Elman, I; Pickar, D; Breier, A 1997. Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine. Biological psychiatry, 42 8, 664-8

Malhotra, A K; Pinals, D A; Adler, C M; Elman, I; Clifton, A; Pickar, D; Breier, A 1997. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 17 3, 141-50

Hillhouse, J J; Stair, A W; Adler, C M 1996. Predictors of sunbathing and sunscreen use in college undergraduates. Journal of behavioral medicine, 19 6, 543-61

Scouten, W H; Adler, C M; Rongen, R; Mallee, L 1992. Evaluation of the mode of binding of immunoglobulin to activated agarose. Journal of chromatography, 597 1-2, 231-8

Rongen, R M; Adler, C M; Scouten, W H 1991. S-Zephyr, a new high performance ion exchange chromatography column matrix. Bioseparation, 2 5, 297-308

Adler, C M; Craske, M G; Kirshenbaum, S; Barlow, D H 1989. 'Fear of panic': an investigation of its role in panic occurrence, phobic avoidance, and treatment outcome. Behaviour research and therapy, 27 4, 391-6

Dehm, E J; Puliafito, C A; Adler, C M; Steinert, R F 1986. Corneal endothelial injury in rabbits following excimer laser ablation at 193 and 248 nm. Archives of ophthalmology (Chicago, Ill. : 1960), 104 9, 1364-8

Puliafito, C A; Steinert, R F; Deutsch, T F; Hillenkamp, F; Dehm, E J; Adler, C M 1985. Excimer laser ablation of the cornea and lens. Experimental studies. Ophthalmology, 92 6, 741-8

Numan, R; Naparzewska, A M; Adler, C M 1984. Absence of reinforcement with low dose intravenous ethanol self-administration in rats. Pharmacology, biochemistry, and behavior, 21 4, 609-15

Adler, C M; McDonough-Ryan, P; Sax, K W; Holland, S K; Arndt, S; Strakowski, S M . fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder. Journal of psychiatric research, 34 4-5, 317-24