Today is

Department of

Pharmacology & Systems Physiology 

Photo of Danuta Malinowska, PhD

Danuta Malinowska, PhD

Research Professor Emerita

Contact Information

Peer Reviewed Publications

Cuppoletti, John; Tewari, Kirti P; Chakrabarti, Jayati; Malinowska, Danuta H 2017. Identification of the fatty acid activation site on human ClC-2. American journal of physiology. Cell physiology, 312 6, C707-C723

Nighot, Meghali P; Nighot, Prashant K; Ma, Thomas Y; Malinowska, Danuta H; Shull, Gary E; Cuppoletti, John; Blikslager, Anthony T 2015. Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion. PloS one, 10 9, e0138174

Cuppoletti, John; Chakrabarti, Jayati; Tewari, Kirti P; Malinowska, Danuta H 2014. Differentiation between human ClC-2 and CFTR Cl- channels with pharmacological agents. American journal of physiology. Cell physiology, 307 5, C479-92

Cuppoletti, John; Chakrabarti, Jayati; Tewari, Kirti; Malinowska, Danuta H 2013. Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents. Cell biochemistry and biophysics, 66 1, 53-63

Cuppoletti, John; Blikslager, Anthony T; Chakrabarti, Jayati; Nighot, Prashant K; Malinowska, Danuta H 2012. Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. BMC pharmacology, 12 , 3

Cuppoletti, John; Malinowska, Danuta H; Tewari, Kirti P; Chakrabarti, Jayati; Ueno, Ryuji 2012. Unoprostone isopropyl and metabolite M1 activate BK channels and prevent ET-1-induced [Ca²?]i increases in human trabecular meshwork and smooth muscle. Investigative ophthalmology & visual science, 53 9, 5178-89

Cuppoletti J, Ferrante CJ & Malinowska DH 2009. Engineered Ion Channels on Synthetic Flexible Membranes: Ion Channel Devices With Focus on Peptides. ASME 2009 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS2009), September 21–23, 2009, Oxnard, California, USA. Sponsor: Aerospace Division. , Volume 2: Multifunctional Materials; Enabling Technologies and Integrated System Design; Structural Health Monitoring/NDE; Bio-Inspired Smart Materials and Structures. ISBN: 978-0-7918-4897-5. Section: Bio-Inspired Smart Materials and Structures , 597-601

Abstract Publications

Cuppoletti J, Malinowska DH & Chakrabarti J 2010. Lubiprostone, but not linaclotide, protects T84 cells against damage to barrier function by interferon-γ. Am College of Gastroenterology meeting 2010, San Antonio TX, October 2010, ,

Cuppoletti J, Malinowska DH, Chakrabarti J, Sekida T & Ueno R 2010. Lubiprostone suppresses growth of colon cancer cells in vitro and in vivo. Am College of Gastroenterology meeting 2010, San Antonio TX, October 2010, ,

Cuppoletti J, Malinowska DH, Tewari KP, Chakrabarti J & Ueno R 2010. Methadone, but not morphine inhibits stimulated chloride currents in ClC-2 transfected cells in culture. DDW 2010, New Orleans LA, May 2010., ,