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Department of

Neurology and Rehabilitation Medicine

Photo of  Soma Sengupta, MD, PhD, MRCP

Soma Sengupta, MD, PhD, MRCP

Dr.

Education/Credentials
  • BSc (HONS): University of Wales
  • PhD: University of Cambridge
  • MB.BChir: University of Cambridge

Board Certifications & Licenses
  • Neuro-oncology UCNS, 2015
  • State Medical Board of Ohio Medical License, 2019
  • American Board of Psychiatry & Neurology, 2011
Contact Information

Peer Reviewed Publications

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Kallay, Laura; Keskin, Havva; Ross, Alexandra; Rupji, Manali; Moody, Olivia A; Wang, Xin; Li, Guanguan; Ahmed, Taukir; Rashid, Farjana; Stephen, Michael Rajesh; Cottrill, Kirsten A; Nuckols, T Austin; Xu, Maxwell; Martinson, Deborah E; Tranghese, Frank; Pei, Yanxin; Cook, James M; Kowalski, Jeanne; Taylor, Michael D; Jenkins, Andrew; Pomeranz Krummel, Daniel A; Sengupta, Soma 2019. Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death. Journal of neuro-oncology, 142 3, 411-422

Karschnia, Philipp; Sengupta, Soma; Dietrich, Jorg 2019. MRI findings in trigeminal neuropathy: bilateral Meckel's cave lesions. Acta neurologica Belgica, ,

Lowder, Lindsey; Hauenstein, Jennifer; Woods, Ashley; Chen, Hsiao-Rong; Rupji, Manali; Kowalski, Jeanne; Olson, Jeffrey J; Saxe, Debra; Schniederjan, Matthew; Neill, Stewart; Weinberg, Brent; Sengupta, Soma 2019. Gliosarcoma: distinct molecular pathways and genomic alterations identified by DNA copy number/SNP microarray analysis. Journal of neuro-oncology, 143 3, 381-392

Archer, Tenley C; Sengupta, Soma; Pomeroy, Scott L 2018. Brain cancer genomics and epigenomics. Handbook of clinical neurology, 148 , 785-797

Clark, Amanda R; Calligaris, David; Regan, Michael S; Pomeranz Krummel, Daniel; Agar, Jeffrey N; Kallay, Laura; MacDonald, Tobey; Schniederjan, Matthew; Santagata, Sandro; Pomeroy, Scott L; Agar, Nathalie Y R; Sengupta, Soma 2018. Rapid discrimination of pediatric brain tumors by mass spectrometry imaging. Journal of neuro-oncology, 140 2, 269-279

Doyle, Sean P; Gurbani, Saumya S; Ross, Alexandra S; Rosen, Havi; Barrett, Charlice Dunn; Olson, Jeffrey J; Shim, Hyunsuk; Shu, Hui-Kuo; Sengupta, Soma 2018. The role of erlotinib and the Optune device in a patient with an epidermal growth factor receptor viii amplified glioblastoma. Oxford medical case reports, 2018 12, omy095

Melms, Johannes C; Ho, Ka-Wai; Thummalapalli, Rohit; Tyler, Janice; Brinker, Titus Josef; Singh, Veena; Sengupta, Soma; Mier, James; Izar, Benjamin 2018. Implementation of cell-free tumor DNA sequencing from the cerebrospinal fluid to guide treatment in a patient with primary leptomeningeal melanoma: A case report. Molecular and clinical oncology, 9 1, 58-61

Sengupta, Soma; Pomeranz Krummel, Daniel; Pomeroy, Scott 2017. The evolution of medulloblastoma therapy to personalized medicine. F1000Research, 6 , 490

Jonas, Oliver; Calligaris, David; Methuku, Kashi Reddy; Poe, Michael M; Francois, Jessica Pierre; Tranghese, Frank; Changelian, Armen; Sieghart, Werner; Ernst, Margot; Krummel, Daniel A Pomeranz; Cook, James M; Pomeroy, Scott L; Cima, Michael; Agar, Nathalie Y R; Langer, Robert; Sengupta, Soma 2016. First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. Journal of biomedical nanotechnology, 12 6, 1297-302

Sengupta, Soma; Voloschin, Alfredo 2016. Redefining Management of Adult Low-Grade Gliomas. Journal of oncology practice, 12 12, 1244-1245

Ippen, Franziska M; Mahadevan, Anand; Wong, Eric T; Uhlmann, Erik J; Sengupta, Soma; Kasper, Ekkehard M 2015. Stereotactic Radiosurgery for Renal Cancer Brain Metastasis: Prognostic Factors and the Role of Whole-Brain Radiation and Surgical Resection. Journal of oncology, 2015 , 636918

Mahadevan, Anand; Sampson, Carrie; LaRosa, Salvatore; Floyd, Scott R; Wong, Eric T; Uhlmann, Erik J; Sengupta, Soma; Kasper, Ekkehard M 2015. Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy. Radiation oncology (London, England), 10 , 245

Christman, Mitalee P; Turbett, Sarah E; Sengupta, Soma; Bakhadirov, Khamidulla U; Williamson, Craig A; Nayak, Lakshmi; Milligan, Tracey; Katz, Joel T 2014. Recurrence of herpes simplex encephalitis associated with temozolomide chemoradiation for malignant glioma: a case report and review of the literature. Oxford medical case reports, 2014 1, 1-4

Sengupta, Soma; Benkers, Tara; Blitstein, Marisa; Palmer, Edwin; Plotkin, Scott R; Abramson, Jeremy S 2014. Posterior reversible encephalopathy syndrome (PRES) complicating newly-diagnosed diffuse large B-cell lymphoma. Clinical lymphoma, myeloma & leukemia, 14 4, e111-3

Sengupta, Soma; Weeraratne, Shyamal D; Cho, Yoon-Jae; Pomeroy, Scott L 2014. Could ?5-GABA-A receptor activation be used as a target for managing medulloblastomas? CNS oncology, 3 4, 245-7

Sengupta, Soma; Weeraratne, Shyamal Dilhan; Sun, Hongyu; Phallen, Jillian; Rallapalli, Sundari K; Teider, Natalia; Kosaras, Bela; Amani, Vladimir; Pierre-Francois, Jessica; Tang, Yujie; Nguyen, Brian; Yu, Furong; Schubert, Simone; Balansay, Brianna; Mathios, Dimitris; Lechpammer, Mirna; Archer, Tenley C; Tran, Phuoc; Reimer, Richard J; Cook, James M; Lim, Michael; Jensen, Frances E; Pomeroy, Scott L; Cho, Yoon-Jae 2014. ?5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. Acta neuropathologica, 127 4, 593-603

Sengupta, Soma; Tarsy, Daniel; Joyce, Robin; Jeyapalan, Suriya 2013. Novel use of dual immunomodulation for treating stiff-person syndrome, cerebellar variant. Movement disorders : official journal of the Movement Disorder Society, 28 13, 1905-6

Pugh, Trevor J; Weeraratne, Shyamal Dilhan; Archer, Tenley C; Pomeranz Krummel, Daniel A; Auclair, Daniel; Bochicchio, James; Carneiro, Mauricio O; Carter, Scott L; Cibulskis, Kristian; Erlich, Rachel L; Greulich, Heidi; Lawrence, Michael S; Lennon, Niall J; McKenna, Aaron; Meldrim, James; Ramos, Alex H; Ross, Michael G; Russ, Carsten; Shefler, Erica; Sivachenko, Andrey; Sogoloff, Brian; Stojanov, Petar; Tamayo, Pablo; Mesirov, Jill P; Amani, Vladimir; Teider, Natalia; Sengupta, Soma; Francois, Jessica Pierre; Northcott, Paul A; Taylor, Michael D; Yu, Furong; Crabtree, Gerald R; Kautzman, Amanda G; Gabriel, Stacey B; Getz, Gad; Jäger, Natalie; Jones, David T W; Lichter, Peter; Pfister, Stefan M; Roberts, Thomas M; Meyerson, Matthew; Pomeroy, Scott L; Cho, Yoon-Jae 2012. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature, 488 7409, 106-10

Weeraratne, Shyamal Dilhan; Amani, Vladimir; Teider, Natalia; Pierre-Francois, Jessica; Winter, Dominic; Kye, Min Jeong; Sengupta, Soma; Archer, Tenley; Remke, Marc; Bai, Alfa H C; Warren, Peter; Pfister, Stefan M; Steen, Judith A J; Pomeroy, Scott L; Cho, Yoon-Jae 2012. Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma. Acta neuropathologica, 123 4, 539-52

Maski, Kiran P; Sengupta, Soma; Silvera, Michelle; Rivkin, Michael J 2011. Intracranial artery dissection in an adolescent with Marfan syndrome. Pediatric neurology, 45 1, 39-41

Sengupta, Soma; Pedersen, Nigel P; Davis, James E; Rojas, Rafael; Reddy, Hasini; Kasper, Ekkehard; Greenstein, Patricia; Wong, Eric T 2011. Illusion of stroke: intravascular lymphomatosis. Reviews in neurological diseases, 8 3-4, e107-13

Nathan, James A; Sengupta, Soma; Wood, Stephen A; Admon, Arie; Markson, Gabriel; Sanderson, Chris; Lehner, Paul J 2008. The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (Copenhagen, Denmark), 9 7, 1130-45

Hewitt, E W; Gupta, S S; Lehner, P J 2001. The human cytomegalovirus gene product US6 inhibits ATP binding by TAP. The EMBO journal, 20 3, 387-96

Karttunen, J T; Lehner, P J; Gupta, S S; Hewitt, E W; Cresswell, P 2001. Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP). Proceedings of the National Academy of Sciences of the United States of America, 98 13, 7431-6

dos Santos, C F; DeWitt, N D; Gupta, S S; Allen, K E; Slayman, C W 2000. Epitope-tagged constructs of the yeast plasma-membrane H(+)-ATPase. IUBMB life, 49 2, 153-9

Gupta, S S; Canessa, C M 2000. Heterologous expression of a mammalian epithelial sodium channel in yeast. FEBS letters, 481 1, 77-80

Gupta, S S; DeWitt, N D; Allen, K E; Slayman, C W 1998. Evidence for a salt bridge between transmembrane segments 5 and 6 of the yeast plasma-membrane H+-ATPase. The Journal of biological chemistry, 273 51, 34328-34

Sen Gupta, S; Kerridge, D; Chevallier, M R 1995. A purine permease in Candida glabrata. FEMS microbiology letters, 126 1, 93-6

Vanden Bossche, H; Warnock, D W; Dupont, B; Kerridge, D; Sen Gupta, S; Improvisi, L; Marichal, P; Odds, F C; Provost, F; Ronin, O 1994. Mechanisms and clinical impact of antifungal drug resistance. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 32 Suppl 1 , 189-202