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Department of Pharmacology & Systems Physiology

Special Master’s Program in Physiology

Fundamentals of Molecular Medicine

Course # GNTD7068C  |  5 Credit Hours

Fall Semester  |  Syllabus (PDF)

Class Meets: M–F 8:00 am – 12:00 pm

Course Directors: Michael A Lieberman, PhD  |  |  Phone: 513-558-5645
John N Lorenz, PhD  |  |  Phone: 513-558-3046
Keith Stringer, MD  |  |  Phone: 513-636-9876

The Fundamentals of Molecular Medicine course prepares students for the organ blocks by presenting foundational concepts and principles in molecular and cellular medicine. This includes an analysis of cellular structures and organelles, protein structure and function, nucleic acid biochemistry, replication and repair of DNA, the processes of transcription and translation, regulation of gene expression, modern molecular techniques used for diagnosis and research, the metabolism of carbohydrates, proteins, purines and pyrimidines, and fatty acids, human genetics (Mendelian and mitochondrial inheritance patterns and probabilities, positional cloning, cytogenetics, imprinting, triplet repeat expansions, multifactorial diseases, tumor suppressors, and the relevance of the human genome project to medicine), signal transduction pathways, and elementary nutrition. Mechanisms by which cells sense and respond to their environment will be presented, along with elementary pharmacodynamics, pharmacokinetics, and the absorption, distribution, metabolism and excretion of pharmacologically active compounds. Students will be introduced to some of the basic concepts and principles of immunology and microbiology.

CARE/Crawley Building

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John Lorenz
Program Director

Bryan Mackenzie
Program Co-Director
Director of Admissions

Jeannie Cummins
Program Manager