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Department of

Molecular Genetics, Biochemistry & Microbiology

Photo of  Agnes Luo, Ph D

Agnes Luo, Ph D

Associate Professor of Molecular Genetics

Education/Credentials
  • Bachelor of Science: Nanjing University
  • Ph D: University of Rochester
  • Post Doctoral Fellow: National Institute of Drug Abuse, NIH
  • Research Fellow: National Institute of Drug Abuse, NIH

Research/Clinical Interests

Molecular Genetics, Neuroscience, Stroke, Regenerative Medicine, Animal Models of Neurological Diseases. For more information on the Luo lab please click here

Contact Information
  • 2256 Medical Sciences Building
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513-558-1188
  • Fax 513-558-5604
  • Email luoy2@ucmail.uc.edu

Peer Reviewed Publications

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Flavia Turcato, Paul Kim, Austin Barnett, Yongming Jin, Mike Scerba, Anthony Casey, Warren Selman, Nigel H. Greig, and Yu Luo 2018. Sequential combined Treatment of Pifithrin-α and Posiphen Enhances Neurogenesis and Functional Recovery After Stroke Cell Transplantation, ,

Hsueh, Shih-Chang; Chen, Kai-Yun; Lai, Jing-Huei; Wu, Chung-Che; Yu, Yu-Wen; Luo, Yu; Hsieh, Tsung-Hsun; Chiang, Yung-Hsiao 2018. Voluntary Physical Exercise Improves Subsequent Motor and Cognitive Impairments in a Rat Model of Parkinson's Disease International journal of molecular sciences, 19 2,

Jin, Yongming; Barnett, Austin; Zhang, Yifan; Yu, Xin; Luo, Yu 2017. Poststroke Sonic Hedgehog Agonist Treatment Improves Functional Recovery by Enhancing Neurogenesis and Angiogenesis Stroke, 48 6, 1636-1645

Kim, Dong Seok; Choi, Ho-Il; Wang, Yun; Luo, Yu; Hoffer, Barry J; Greig, Nigel H 2017. A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway Cell transplantation, 26 9, 1560-1571

Lu, Tao; Kim, Paul P; Greig, Nigel H; Luo, Yu 2017. Dopaminergic Neuron-Specific Deletion of p53 Gene Attenuates Methamphetamine Neurotoxicity Neurotoxicity research, 32 2, 218-230

Filichia, Emily; Hoffer, Barry; Qi, Xin; Luo, Yu 2016. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP Scientific reports, 6 , 32656

Guo, Xing; Sun, XiaoYan; Hu, Di; Wang, Ya-Juan; Fujioka, Hisashi; Vyas, Rajan; Chakrapani, Sudha; Joshi, Amit Umesh; Luo, Yu; Mochly-Rosen, Daria; Qi, Xin 2016. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease Nature communications, 7 , 12646

Liu, H-S; Shen, H; Luo, Y; Hoffer, B J; Wang, Y; Yang, Y 2016. Post-treatment with cocaine- and amphetamine-regulated transcript enhances infarct resolution, reinnervation, and angiogenesis in stroke rats - an MRI study NMR in biomedicine, 29 3, 361-70

Qi, Xin; Davis, Brandon; Chiang, Yung-Hsiao; Filichia, Emily; Barnett, Austin; Greig, Nigel H; Hoffer, Barry; Luo, Yu 2016. Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model Journal of neurochemistry, 138 5, 746-57

Sheng, Yang; Filichia, Emily; Shick, Elizabeth; Preston, Kenzie L; Phillips, Karran A; Cooperman, Leslie; Lin, Zhicheng; Tesar, Paul; Hoffer, Barry J; Luo, Yu 2016. Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs The American journal of psychiatry, 173 4, 429-31

Sheng, Yang; Filichia, Emily; Shick, Elizabeth; Preston, Kenzie L; Phillips, Karran A; Cooperman, Leslie; Lin, Zhicheng; Tesar, Paul; Hoffer, Barry; Luo, Yu 2016. Using iPSC-derived human DA neurons from opioid-dependent subjects to study dopamine dynamics Brain and behavior, 6 8, e00491

Wang, Jin-Ya; Huang, Ya-Ni; Chiu, Chong-Chi; Tweedie, David; Luo, Weiming; Pick, Chaim G; Chou, Szu-Yi; Luo, Yu; Hoffer, Barry J; Greig, Nigel H; Wang, Jia-Yi 2016. Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat Journal of neuroinflammation, 13 1, 168

Yang, Ling-Yu; Greig, Nigel H; Huang, Ya-Ni; Hsieh, Tsung-Hsun; Tweedie, David; Yu, Qian-Sheng; Hoffer, Barry J; Luo, Yu; Kao, Yu-Chieh; Wang, Jia-Yi 2016. Post-traumatic administration of the p53 inactivator pifithrin-O oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury Neurobiology of disease, 96 , 216-226

Zhou, Xiaofei; Pace, Jonathan; Filichia, Emily; Lv, Tao; Davis, Brandon; Hoffer, Barry; Selman, Warren; Luo, Yu 2016. Effect of the sonic hedgehog receptor smoothened on the survival and function of dopaminergic neurons Experimental neurology, 283 Pt A, 235-45

Filichia, E; Shen, H; Zhou, X; Qi, X; Jin, K; Greig, N; Hoffer, B; Luo, Y 2015. Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model Neuroscience, 295 , 1-10

Jin, Yongmin; Raviv, Nataly; Barnett, Austin; Bambakidis, Nicholas C; Filichia, Emily; Luo, Yu 2015. The shh signaling pathway is upregulated in multiple cell types in cortical ischemia and influences the outcome of stroke in an animal model PloS one, 10 4, e0124657

Luo, Yu; Hoffer, Alan; Hoffer, Barry; Qi, Xin 2015. Mitochondria: A Therapeutic Target for Parkinson's Disease? International journal of molecular sciences, 16 9, 20704-30

Yu Luo, Hui Shen, Hua‐Shan Liu, Seong‐Jin Yu, David Reiner, Brandon K. Harvey, Barry J. Hoffer, Yihong Yang, and Yun Wang 2013. CART peptide induces neuroregeneration in stroke rats Journal of Cerebral Blood Flow and Metabolism , 33 2, 300-10

Yu Luo, Chi-Chung Kuo, Hui Shen, Jenny Chou, Nigel H. Greig, Barry J. Hoffer, Yun Wang 2009. Delayed treatment with a p53 inhibitor enhances functional recovery in stroke brain Ann Neurol, 65 5, 520-30

Yu Luo, Feng Xing, Rita Guiliano, Howard J. Federoff 2008. Identification of a novel Nurr1 interacting protein J Neurosci, 28 37, 9277-86

Yu Luo, Leigh A. Henricksen, Rita E. Giuliano, Landa Prifti, Linda M. Callahan and Howard J. Federoff 2007. VIP is a transcriptional target of Nurr1 in dopaminergic cells Experimental Neurology, 203 1, 221-232