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Department of

Molecular Genetics, Biochemistry & Microbiology

Photo of  Eric Gruenstein, PhD

Eric Gruenstein, PhD

Professor of Molecular Genetics

Education/Credentials
  • PhD: Duke University
  • Post Doc: NIH
  • MDA Association Fellow: MIT

Research/Clinical Interests

Research in my lab is focused on understanding the mechanisms by which neurons regulate synaptic strength. These processes are thought to provide the basis for learning and memory. In particular, we are interested in how neurons decode cytoplasmic calcium oscillations that are associated with the long term potentiation of synaptic signaling.

Contact Information
  • Office 2980 Cardiovascular Center
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office (513)558-5531
  • Fax (513)558-8474
  • Email eric.gruenstein@uc.edu

Peer Reviewed Publications

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Gruenstein, Eric I; Schlemm, Donna J; Bethi, Mridula; Keller, Stephen J 2018. The early signaling pathway of live yeast cell derivative in THP-1 monocytes. Cell calcium, 73 , 112-120

French, D A; Gruenstein, E I 2006. An integrate-and-fire model for synchronized bursting in a network of cultured cortical neurons. Journal of computational neuroscience, 21 3, 227-41

Kutcher, Louis W; Beauman, Shirelyn R; Gruenstein, Eric I; Kaetzel, Marcia A; Dedman, John R 2003. Nuclear CaMKII inhibits neuronal differentiation of PC12 cells without affecting MAPK or CREB activation. American journal of physiology. Cell physiology, 284 6, C1334-45

Wang, X-S, E. Gruenstein, and F. Zemlan 1998. Apolipoprotein E (ApoE) Peptide Regulates Tau Phosphorylation via Two Different Signaling Pathways J Neurosci. Res, 51 , 658

Wang, X; Gruenstein, E I 1997. Mechanism of synchronized Ca2+ oscillations in cortical neurons. Brain research, 767 2, 239-49

Wang, X-S., and E. Gruenstein 1997. The Rapid Elevation of Neuronal Cytoplasmic Calcium by Apolipoprotein E Peptide J. Cell. Physiol , 173 , 73

Wang, X-S., G. Ciraolo, R. Morris, and E. Gruenstein 1997. Identification of a Neuronal Endocytic Pathway Activated by an Apolipoprotein E Receptor Binding Peptide Brain Res, 778 , 6