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VidjayaLetchoumy VummidiPremkumar, PhD

Apr 9, 2020, 16:10 PM
Viji joined Dr. Waltz’s lab as a Postdoctoral Fellow in 2014. Her main focus is to explore the role of cell type specific HGFL dependent RON signaling in breast cancer development and metastasis. Epithelial specific Ron activation is involved in the recruitment and polarization of macrophages to the tumor environment. Ron signaling in these tumor-recruited macrophages activates secretion of chemokines that play key homeostatic functions in tumor development and metastasis. However the pathway through which RON activates macrophages to reach a tumor promoting state is poorly understood. She is currently working to define the mechanism by which RON signaling is involved in tumor cell, crosstalk with macrophages and how the communication between these two cell types promote tumorigenesis. To investigate the pathway, she uses an in vitro co-culture model and screens several molecular targets that are involved in the RON signaling pathway.
Name : VidjayaLetchoumy VummidiPremkumar, PhD
Title : Postdoctoral Fellow
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