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Department of Internal Medicine

Nephrology and Hypertension

Photo of  Hassane Amlal, PhD

Hassane Amlal, PhD

Research Associate Professor of Medicine

Education/Credentials
  • Bachelor's Degree: University Cadi Ayyad
  • Certificate of Physiology: University of Nancy I
  • Master's Degree: University Pierre et Marie Curie (Paris 6)
  • Doctoral Degree: University Pierre et Marie Curie (Paris 6)

Contact Information
  • University of Cincinnati College of Medicine
  • Room 6116
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513-558-2880
  • Fax 513-558-4309
  • Email hassane.amlal@uc.edu

Peer Reviewed Publications

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Dos Santos, Ingrid F; Sheriff, Sulaiman; Amlal, Sihame; Ahmed, Rafeeq P H; Thakar, Charuhas V; Amlal, Hassane 2019. Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury. American journal of physiology. Renal physiology, 316 4, F743-F757

Webster, Rose; Sheriff, Sulaiman; Faroqui, Rashma; Siddiqui, Faraaz; Hawse, John R; Amlal, Hassane 2016. Klotho/fibroblast growth factor 23- and PTH-independent estrogen receptor-?-mediated direct downregulation of NaPi-IIa by estrogen in the mouse kidney. American journal of physiology. Renal physiology, 311 2, F249-59

Burris, Dara; Webster, Rose; Sheriff, Sulaiman; Faroqui, Rashma; Levi, Moshe; Hawse, John R; Amlal, Hassane 2015. Estrogen directly and specifically downregulates NaPi-IIa through the activation of both estrogen receptor isoforms (ER? and ER?) in rat kidney proximal tubule. American journal of physiology. Renal physiology, 308 6, F522-34

Hsieh, H; Amlal, H; Genter, M B 2015. Evaluation of the toxicity of zinc in the rat olfactory neuronal cell line, Odora. Human & experimental toxicology, 34 3, 308-14

Saito, Atsushi; Nikolaidis, Nikolaos M; Amlal, Hassane; Uehara, Yasuaki; Gardner, Jason C; LaSance, Kathleen; Pitstick, Lori B; Bridges, James P; Wikenheiser-Brokamp, Kathryn A; McGraw, Dennis W; Woods, Jason C; Sabbagh, Yves; Schiavi, Susan C; Altini?ik, Göksel; Jakopovi?, Marko; Inoue, Yoshikazu; McCormack, Francis X 2015. Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment. Science translational medicine, 7 313, 313ra181

Amlal, Hassane; Xu, Jie; Barone, Sharon; Zahedi, Kamyar; Soleimani, Manoocher 2013. The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion. Journal of molecular medicine (Berlin, Germany), 91 5, 561-72

Barone, Sharon; Amlal, Hassane; Xu, Jie; Soleimani, Manoocher 2012. Deletion of the Cl-/HCO3- exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27 4, 1368-79

Soleimani, Manoocher; Barone, Sharon; Xu, Jie; Shull, Gary E; Siddiqui, Faraz; Zahedi, Kamyar; Amlal, Hassane 2012. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure. Proceedings of the National Academy of Sciences of the United States of America, 109 33, 13368-73

Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. American journal of physiology. Gastrointestinal and liver physiology, 303 5, G546-60

Abu Hossain, Shaikh; Chaudhry, Farrukh A; Zahedi, Kamyar; Siddiqui, Faraaz; Amlal, Hassane 2011. Cellular and molecular basis of increased ammoniagenesis in potassium deprivation. American journal of physiology. Renal physiology, 301 5, F969-78

Amlal, Hassane; Soleimani, Manoocher 2011. Pendrin as a novel target for diuretic therapy. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 28 3, 521-6

Amlal, Hassane; Petrovic, Snezana; Xu, Jie; Wang, Zhaohui; Sun, Xuming; Barone, Sharon; Soleimani, Manoocher 2010. Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct. American journal of physiology. Cell physiology, 299 1, C33-41

Sheriff, Sulaiman; Ali, Marwan; Yahya, Ayesha; Haider, Khawaja H; Balasubramaniam, Ambikaipakan; Amlal, Hassane 2010. Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line. Molecular cancer research : MCR, 8 4, 604-14

Zahedi, Kamyar; Barone, Sharon; Kramer, Debora L; Amlal, Hassane; Alhonen, Leena; Jänne, Juhani; Porter, Carl W; Soleimani, Manoocher 2010. The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury. American journal of physiology. Cell physiology, 299 1, C164-74

Balkovetz, Daniel F; Chumley, Phillip; Amlal, Hassane 2009. Downregulation of claudin-2 expression in renal epithelial cells by metabolic acidosis. American journal of physiology. Renal physiology, 297 3, F604-11

Barone, Sharon; Fussell, Stacey L; Singh, Anurag Kumar; Lucas, Fred; Xu, Jie; Kim, Charles; Wu, Xudong; Yu, Yiling; Amlal, Hassane; Seidler, Ursula; Zuo, Jian; Soleimani, Manoocher 2009. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension. The Journal of biological chemistry, 284 8, 5056-66

Xu, Jie; Song, Penghong; Nakamura, Suguru; Miller, Marian; Barone, Sharon; Alper, Seth L; Riederer, Brigitte; Bonhagen, Janina; Arend, Lois J; Amlal, Hassane; Seidler, Ursula; Soleimani, Manoocher 2009. Deletion of the chloride transporter slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion. The Journal of biological chemistry, 284 43, 29470-9

Faroqui, S; Levi, M; Soleimani, M; Amlal, H 2008. Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia. Kidney international, 73 10, 1141-50

Petrovic, Snezana; Barone, Sharon; Wang, Zhaohui; McDonough, Alicia A; Amlal, Hassane; Soleimani, Manoocher 2008. Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule. American journal of nephrology, 28 2, 330-8

Petrovic,S.; Barone,S.; Wang,Z.; McDonough,A.A.; Amlal,H.; Soleimani,M. 2008. Slc26a6 (pat1) deletion downregulates the apical Na+/H + exchanger in the straight segment of the proximal tubule American Journal of Nephrology, 28 2, 330

Singh, Anurag Kumar; Amlal, Hassane; Haas, Patrick J; Dringenberg, Ulrike; Fussell, Stacey; Barone, Sharon L; Engelhardt, Regina; Zuo, Jian; Seidler, Ursula; Soleimani, Manoocher 2008. Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5. Kidney international, 74 4, 438-47

Barone, Sharon; Amlal, Hassane; Kujala, Minna; Xu, Jie; Karet, Fiona; Blanchard, Ann; Kere, Juha; Soleimani, Manoocher 2007. Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 22 12, 3462-70

Barone,S.; Amlal,H.; Kujala,M.; Xu,J.; Karet,F.; Blanchard,A.; Kere,J.; Soleimani,M. 2007. Regulation of the basolateral chloride/base exchangers ae1 and slc26a7 in the kidney collecting duct in potassium depletion Nephrology Dialysis Transplantation, 22 12, 3462

Wagner, Erin A; Falciglia, Grace A; Amlal, Hassane; Levin, Linda; Soleimani, Manoocher 2007. Short-term exposure to a high-protein diet differentially affects glomerular filtration rate but not Acid-base balance in older compared to younger adults. Journal of the American Dietetic Association, 107 8, 1404-8

Wagner,E.A.; Falciglia,G.A.; Amlal,H.; Levin,L.; Soleimani,M. 2007. Short-term exposure to a high-protein diet differentially affects glomerular filtration rate but not acid-base balance in older compared to younger adults Journal of the American Dietetic Association, 107 8, 1404

Amlal, Hassane; Faroqui, Somia; Balasubramaniam, Ambikaipakan; Sheriff, Sulaiman 2006. Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line. Cancer research, 66 7, 3706-14

Amlal, Hassane; Sheriff, Sulaiman; Faroqui, Somia; Ma, Liyun; Barone, Sharone; Petrovic, Snezana; Soleimani, Manoocher 2006. Regulation of acid-base transporters by vasopressin in the kidney collecting duct of Brattleboro rat. American journal of nephrology, 26 2, 194-205

Amlal,H.; Faroqui,S.; Balasubramaniam,A.; Sheriff,S. 2006. Estrogen up-regulates neuropeptide y y1 receptor expression in a human breast cancer cell line Cancer Research, 66 7, 3706

Amlal,H.; Sheriff,S.; Faroqui,S.; Ma,L.; Barone,S.; Petrovic,S.; Soleimani,M. 2006. Regulation of acid-base transporters by vasopressin in the kidney collecting duct of brattleboro rat American Journal of Nephrology, 26 2, 194

Faroqui, Somia; Sheriff, Sulaiman; Amlal, Hassane 2006. Metabolic acidosis has dual effects on sodium handling by rat kidney. American journal of physiology. Renal physiology, 291 2, F322-31

Faroqui,S.; Sheriff,S.; Amlal,H. 2006. Metabolic acidosis has dual effects on sodium handling by rat kidney American Journal of Physiology - Renal Physiology, 291 2, F322

Petrovic, Snezana; Amlal, Hassane; Sun, Xuming; Karet, Fiona; Barone, Sharon; Soleimani, Manoocher 2006. Vasopressin induces expression of the Cl-/HCO3- exchanger SLC26A7 in kidney medullary collecting ducts of Brattleboro rats. American journal of physiology. Renal physiology, 290 5, F1194-201

Petrovic,S.; Amlal,H.; Sun,X.; Karet,F.; Barone,S.; Soleimani,M. 2006. Vasopressin induces expression of the cl-/hco3 - exchanger slc26a7 in kidney medullary collecting ducts of brattleboro rats American Journal of Physiology - Renal Physiology, 290 5, F1194

Xu, Jie; Worrell, Roger T; Li, Hong C; Barone, Sharon L; Petrovic, Snezana; Amlal, Hassane; Soleimani, Manoocher 2006. Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion. Journal of the American Society of Nephrology : JASN, 17 4, 956-67

Xu,J.; Worrell,R.T.; Li,H.C.; Barone,S.L.; Petrovic,S.; Amlal,H.; Soleimani,M. 2006. Chloride/bicarbonate exchanger slc26a7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion Journal of the American Society of Nephrology, 17 4, 956

Wilke, Catherine; Sheriff, Sulaiman; Soleimani, Manoocher; Amlal, Hassane 2005. Vasopressin-independent regulation of collecting duct aquaporin-2 in food deprivation. Kidney international, 67 1, 201-16

Wilke,C.; Sheriff,S.; Soleimani,M.; Amlal,H. 2005. Vasopressin-independent regulation of collecting duct aquaporin-2 in food deprivation Kidney International, 67 1, 201

Amlal, Hassane; Sheriff, Sulaiman; Soleimani, Manoocher 2004. Upregulation of collecting duct aquaporin-2 by metabolic acidosis: role of vasopressin. American journal of physiology. Cell physiology, 286 5, C1019-30

Amlal,H.; Sheriff,S.; Soleimani,M. 2004. Upregulation of collecting duct aquaporin-2 by metabolic acidosis: role of vasopressin American Journal of Physiology - Cell Physiology, 286 5 55-5, C1019

Barone, Sharon; Amlal, Hassane; Xu, Jie; Kujala, Minna; Kere, Juha; Petrovic, Snezana; Soleimani, Manoocher 2004. Differential regulation of basolateral Cl-/HCO3- exchangers SLC26A7 and AE1 in kidney outer medullary collecting duct. Journal of the American Society of Nephrology : JASN, 15 8, 2002-11

Barone,S.; Amlal,H.; Xu,J.; Kujala,M.; Kere,J.; Petrovic,S.; Soleimani,M. 2004. Differential regulation of basolateral cl-/hco3 - exchangers slc26a7 and ae1 in kidney outer medullary collecting duct Journal of the American Society of Nephrology, 15 8, 2002

Nonoguchi,H.; Inoue,T.; Mori,T.; Nakayama,Y.; Kohda,Y.; Tomita,K.; Amlal,H.; Sheriff,S.; Soleimani,M. 2004. Regulation of aquaporin-2 by metabolic acidosis (multiple letters) American Journal of Physiology - Cell Physiology, 287 3 56-3, C814

Amlal, Hassane; Ledoussal, Clara; Sheriff, Sulaiman; Shull, Gary E; Soleimani, Manoocher 2003. Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+-H+ exchanger NHE3. The Journal of physiology, 553 Pt 2, 511-22

Amlal, Hassane; Wilke, Catherine 2003. Resistance of mTAL Na+-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats. Kidney international, 64 2, 544-54

Amlal,H.; Ledoussal,C.; Sheriff,S.; Shull,G.E.; Soleimani,M. 2003. Downregulation of renal aqp2 water channel and nkcc2 in mice lacking the apical na+-h+ exchanger nhe3 Journal of Physiology, 553 2, 511

Amlal,H.; Wilke,C. 2003. Resistance of mtal na+-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats Kidney International, 64 2, 544

Xu, Jie; Wang, Zhaohui; Barone, Sharone; Petrovic, Milan; Amlal, Hassane; Conforti, Laura; Petrovic, Snezana; Soleimani, Manoocher 2003. Expression of the Na+-HCO-3 cotransporter NBC4 in rat kidney and characterization of a novel NBC4 variant. American journal of physiology. Renal physiology, 284 1, F41-50

Xu,J.; Wang,Z.; Barone,S.; Petrovic,M.; Amlal,H.; Conforti,L.; Petrovic,S.; Soleimani,M. 2003. Expression of the na+-hco3 - cotransporter nbc4 in rat kidney and characterization of a novel nbc4 variant American Journal of Physiology - Renal Physiology, 284 1 53-1, F41

Amlal, H; Chen, Q; Greeley, T; Pavelic, L; Soleimani, M 2001. Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading. Kidney international, 60 5, 1824-36

Amlal, H; Chen, Q; Habo, K; Wang, Z; Soleimani, M 2001. Fasting downregulates renal water channel AQP2 and causes polyuria. American journal of physiology. Renal physiology, 280 3, F513-23

Amlal,H.; Chen,Q.; Greeley,T.; Pavelic,L.; Soleimani,M. 2001. Coordinated down-regulation of nbc-1 and nhe-3 in sodium and bicarbonate loading Kidney International, 60 5, 1824

Amlal,H.; Chen,Q.; Habo,K.; Wang,Z.; Soleimani,M. 2001. Fasting downregulates renal water channel aqp2 and causes polyuria American Journal of Physiology - Renal Physiology, 280 3 49-3, F513

Amlal,H.; Habo,K.; Soleimani,M. 2001. Erratum: potassium deprivation upregulates expression of renal basolateral na+-hco3 cotransporter (nbc-1) (american journal of physiology (september 2000) 279 (f532-f543)) American Journal of Physiology - Renal Physiology, 280 6 49-6,

Attmane-Elakeb,A.; Amlal,H.; Bichara,M. 2001. Ammonium carriers in medullary thick ascending limb American Journal of Physiology - Renal Physiology, 280 1 49-1, F1

Soleimani, M; Greeley, T; Petrovic, S; Wang, Z; Amlal, H; Kopp, P; Burnham, C E 2001. Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex. American journal of physiology. Renal physiology, 280 2, F356-64

Soleimani,M.; Greeley,T.; Petrovic,S.; Wang,Z.; Amlal,H.; Kopp,P.; Burnham,C.E. 2001. Pendrin: an apical cl-/oh-/hco3 - exchanger in the kidney cortex American Journal of Physiology - Renal Physiology, 280 2 49-2, F356

Wang, Z; Conforti, L; Petrovic, S; Amlal, H; Burnham, C E; Soleimani, M 2001. Mouse Na+: HCO3- cotransporter isoform NBC-3 (kNBC-3): cloning, expression, and renal distribution. Kidney international, 59 4, 1405-14

Wang,Z.; Conforti,L.; Petrovic,S.; Amlal,H.; Burnham,C.E.; Soleimani,M. 2001. Mouse na+:hco3 - cotransporter isoform nbc-3 (knbc-3): cloning, expression, and renal distribution Kidney International, 59 4, 1405

Ali, R; Amlal, H; Burnham, C E; Soleimani, M 2000. Glucocorticoids enhance the expression of the basolateral Na+:HCO3- cotransporter in renal proximal tubules. Kidney international, 57 3, 1063-71

Ali,R.; Amlal,H.; Burnham,C.E.; Soleimani,M. 2000. Glucocorticoids enhance the expression of the basolateral na+:hco3 - cotransporter in renal proximal tubules Kidney International, 57 3, 1063

Amlal, H; Habo, K; Soleimani, M 2000. Potassium deprivation upregulates expression of renal basolateral Na(+)-HCO(3)(-) cotransporter (NBC-1). American journal of physiology. Renal physiology, 279 3, F532-43

Amlal, H; Krane, C M; Chen, Q; Soleimani, M 2000. Early polyuria and urinary concentrating defect in potassium deprivation. American journal of physiology. Renal physiology, 279 4, F655-63

Amlal,H.; Habo,K.; Soleimani,M. 2000. Potassium deprivation upregulates expression of renal basolateral na+-hco3/- cotransporter (nbc-1) American Journal of Physiology - Renal Physiology, 279 3 48-3, F532

Amlal,H.; Krane,C.M.; Chen,Q.; Soleimani,M. 2000. Early polyuria and urinary concentrating defect in potassium deprivation American Journal of Physiology - Renal Physiology, 279 4 48-4, F655

Nakamura, S; Amlal, H; Soleimani, M; Galla, J H 2000. Pathways for HCO3-reabsorption in mouse medullary collecting duct segments. The Journal of laboratory and clinical medicine, 136 3, 218-23

Nakamura,S.; Amlal,H.; Soleimani,M.; Galla,J.H. 2000. Pathways for hco3 - reabsorption in mouse medullary collecting duct segments Journal of Laboratory and Clinical Medicine, 136 3, 218

Amlal, H; Burnham, C E; Soleimani, M 1999. Characterization of Na+/HCO-3 cotransporter isoform NBC-3. The American journal of physiology, 276 6 Pt 2, F903-13

Amlal,H.; Burnham,C.E.; Soleimani,M. 1999. Erratum: characterization of na+/hco3/- cotransporter isoform nbc-3 (american journal of physiology-advances in physiology education (june 1999) 276:46 (f903-f913)) American Journal of Physiology - Advances in Physiology Education, 22 1,

Amlal,H.; Burnham,C.E.; Soleimani,M. 1999. Characterization of na+/hco3/- cotransporter isoform nbc-3 American Journal of Physiology - Renal Physiology, 276 6 45-6, F903

Amlal,H.; Burnham,C.E.; Soleimani,M. 1999. Erratum: characterization of na+/hco3/- cotransporter isoform nbc-3 (american journal of physiology - renal physiology (june 1999) 276 (f903- f913)) American Journal of Physiology - Renal Physiology, 277 3 46-3,

Nakamura, S; Amlal, H; Schultheis, P J; Galla, J H; Shull, G E; Soleimani, M 1999. HCO-3 reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. The American journal of physiology, 276 6 Pt 2, F914-21

Nakamura,S.; Amlal,H.; Galla,J.H.; Soleimani,M. 1999. Nh4 + secretion in inner medullary collecting duct in potassium deprivation: role of colonic h+-k+-atpase Kidney International, 56 6, 2160

Nakamura,S.; Amlal,H.; Schultheis,P.J.; Galla,J.H.; Shull,G.E.; Soleimani,M. 1999. Hco3/- reabsorption in renal collecting duct of nhe-3-deficient mouse: a compensatory response American Journal of Physiology - Renal Physiology, 276 6 45-6, F914

Shumaker, H; Amlal, H; Frizzell, R; Ulrich, C D; Soleimani, M 1999. CFTR drives Na+-nHCO-3 cotransport in pancreatic duct cells: a basis for defective HCO-3 secretion in CF. The American journal of physiology, 276 1 Pt 1, C16-25

Shumaker,H.; Amlal,H.; Frizzell,R.; Ulrich II,C.D.; Soleimani,M. 1999. Cftr drives na+-nhcp3/- cotransport in pancreatic duct cells: a basis for defective hco3/- secretion in cf American Journal of Physiology - Cell Physiology, 276 1 45-1, C16

Amlal, H; Goel, A; Soleimani, M 1998. Activation of H+-ATPase by hypotonicity: a novel regulatory mechanism for H+ secretion in IMCD cells. The American journal of physiology, 275 4 Pt 2, F487-501

Amlal, H; Wang, Z; Burnham, C; Soleimani, M 1998. Functional characterization of a cloned human kidney Na+:HCO3- cotransporter. The Journal of biological chemistry, 273 27, 16810-5

Amlal, H; Wang, Z; Soleimani, M 1998. Potassium depletion downregulates chloride-absorbing transporters in rat kidney. The Journal of clinical investigation, 101 5, 1045-54

Amlal,H.; Goel,A.; Soleimani,M. 1998. Activation of h+-atpase by hypotonicity: a novel regulatory mechanism for h+ secretion in imcd cells American Journal of Physiology - Renal Physiology, 275 4 44-4, F487

Amlal,H.; LeGoff,C.; Vernimmen,C.; Soleimani,M.; Paillard,M.; Bichara,M. 1998. Ang ii controls na+-k+(NH4/+)-2cl- cotransport via 20-hete and pkc in medullary thick ascending limb American Journal of Physiology - Cell Physiology, 274 4 43-4, C1047

Amlal,H.; Wang,Z.; Burnham,C.; Soleimani,M. 1998. Functional characterization of a cloned human kidney na+:hco3/- cotransporter Journal of Biological Chemistry, 273 27, 16810

Amlal,H.; Wang,Z.; Soleimani,M. 1998. Potassium depletion downregulates chloride-absorbing transporters in rat kidney Journal of Clinical Investigation, 101 5, 1045

Burnham, C E; Flagella, M; Wang, Z; Amlal, H; Shull, G E; Soleimani, M 1998. Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter. The American journal of physiology, 274 6 Pt 2, F1119-26

Burnham,C.E.; Flagella,M.; Wang,Z.; Amlal,H.; Shull,G.E.; Soleimani,M. 1998. Cloning, renal distribution, and regulation of the rat na+-hco3/- cotransporter American Journal of Physiology - Renal Physiology, 274 6 43-6, F1119

Nakamura, S; Amlal, H; Galla, J H; Soleimani, M 1998. Colonic H+-K+-ATPase is induced and mediates increased HCO3- reabsorption in inner medullary collecting duct in potassium depletion. Kidney international, 54 4, 1233-9

Nakamura,S.; Amlal,H.; Galla,J.H.; Soleimani,M. 1998. Colonic h+-k+-atpase is induced and mediates increased hco3- reabsorption in inner medullary collecting duct in potassium depletion Kidney International, 54 4, 1233

Amlal, H; Soleimani, M 1997. K+/NH4+ antiporter: a unique ammonium carrying transporter in the kidney inner medulla. Biochimica et biophysica acta, 1323 2, 319-33

Amlal, H; Wang, Z; Soleimani, M 1997. Functional upregulation of H+-ATPase by lethal acid stress in cultured inner medullary collecting duct cells. The American journal of physiology, 273 4 Pt 1, C1194-205

Amlal,H.; Soleimani,M. 1997. K+/nh4 + antiporter: a unique ammonium carrying transporter in the kidney inner medulla Biochimica et Biophysica Acta - Biomembranes, 1323 2, 319

Amlal,H.; Wang,Z.; Soleimani,M. 1997. Functional upregulation of h+-atpase by lethal acid stress in cultured inner medullary collecting duct cells American Journal of Physiology - Cell Physiology, 273 4 42-4, C1194

Burnham, C E; Amlal, H; Wang, Z; Shull, G E; Soleimani, M 1997. Cloning and functional expression of a human kidney Na+:HCO3- cotransporter. The Journal of biological chemistry, 272 31, 19111-4

Burnham,C.E.; Amlal,H.; Wang,Z.; Shull,G.E.; Soleimani,M. 1997. Cloning and functional expression of a human kidney na+:hoc3 - cotransporter Journal of Biological Chemistry, 272 31, 19111

Amlal,H.; Legoff,C.; Vernimmen,C.; Paillard,M.; Bichara,M. 1996. Na+-k+(nh4/+)-2cl- cotransport in medullary thick ascending limb: control by pka, pkc, and 20-hete American Journal of Physiology - Cell Physiology, 271 2 40-2, C455

Amlal,H.; Soleimani,M. 1996. Induction of h+-atpase by lethal acid stress: a mechanism for survival and accelerated growth in cultured inner medullary collecting duct cells Journal of the American Society of Nephrology, 7 9, 1250

Amlal,H.; Soleimani,M. 1996. Activation of h+-atpase by hypotonicity: a novel regulatory mechanism for h+ transport in inner medulla Journal of the American Society of Nephrology, 7 9, 1250

Amlal,H.; Soleimani,M. 1996. K+/nh4+ antiporter: a unique ammonium carrying transporter in the kidney inner medulla Journal of the American Society of Nephrology, 7 9, 1250

Amlal,H.; Paillard,M.; Bichara,M. 1994. Cl--dependent nh4/+ transport mechanisms in medullary thick ascending limb cells American Journal of Physiology - Cell Physiology, 267 6 36-6, C1607

Amlal,H.; Paillard,M.; Bichara,M. 1994. Nh4/+ transport pathways in cells of medullary thick ascending limb of rat kidney. nh4/+ conductance and k+/nh4/+(h+) antiport Journal of Biological Chemistry, 269 35, 21962

Published Abstracts

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Barone S, Xu J, Amlal H, Soleimani M 2011. Deletion of the Cl-/HCO3-exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting J Am Soc Nephrol, 22 , 268A


Li H, Zhaopeng D, Barone S, Amlal H, McDonough A, Wang T, Soleimani M 2011. Generation and examination of proximal tubule specific Na+/H+ exchanger NHE3 knockout mouse J Am Soc Nephrol, 22 , 79A


Quian C, Soleimani M, Amlal H 2011. Impaired urinary concentrating ability in aged Sprague Dawley rats J Am Soc Nephrol, 12 , 14A


Siddiqui F, Levi M, Amlal H 2011. Estrogen causes phosphaturia through specific downregulation of NaPi-IIa via the activation of both estrogen receptors ERx and ERb J Am Soc Nephrol, 22 , 743A


Siddiqui F, Soleimani M, Amlal H 2011. Deletion of glutamine/neutral amino acid transporter ASCT2 (ATB0) does not alter acid-base regulation under baseline condition or in response to acid loading J Am Soc Nephrol, 22 , 264A


Soleimani M, Amlal H, Barone S, Xu J, Siddiqui F 2011. Double-knockout of pendrin and NaCl cotransporter causes salt wasting, profound dehydration and nephrogenic diabetes insipidus J Am Soc Nephrol, 22 , 80A


Amlal H 2010. Role of glutamine transport and metabolism in the development of renal hypertrophy J Am Soc Nephrol, 21 , 480A


Amlal H, Barone S, Xi J, Soleimani M 2010. Pendrin conferes partial resistance to the diuretic effect of loop and thiazide diuretics in mice J Am Soc Nephrol, 21 , 480A


Amlal H, Barone S, Xu J, Zahedi K, Soleimani M 2010. The anion transporter Slc26a9 plays an important role in systemic blood pressure control by regulating renal chloride excretion J Am Soc Nephrol, 21 , 109A


Amlal H 2009. Estrogen downregulates the expression of 24-hydroxylase (CYP24A1) in the kidney cortex of ovariectomized rats J Am Soc Nephrol, 20 , 539A


Amlal H, Xu J, Petrovic S, Barone S, Miller M, Soleimani M 2009. Deletion of Slc26a4 (pendrin) impairs bicarbonate secretion in the collecting duct but does not affect the apical Cl-/HCO3-exchanger activity in B-intercalated cells J Am Soc Nephrol, 20 , 33A


Xu J, Song P, Nakamura S, Miller M, Barone S, Alper S, Riederer B, Bonhagen J, Arend L, Amlal H, Siedler U, Soleimani M 2009. Deletion of the chloride/base exchanger Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion J Am Soc Nephrol, 20 , 33A


Amlal H, Barone S, Sharif S, Zuo J, Soleimani M 2008. Deletion of the fructose-facilitated transporter Glut5 confers insulin resistance J Am Soc Nephrol, 18 , 647A


Amlal H, Barone S, Xu Jie, Soleimani M 2008. Ablation of the chloride/base exchanger Slc26a6 (PAT1: CFEX) blocks fructose-induced hypertension in part by increasing salt excretion in the kidny J Am Soc Nephrol, 18 , 347A


Barone S, Fussell S, Singh A, Amlal H, Xu J, Seidler U, Zuo J, Soleimani M 2008. The Slc2a5 (Glut5) is absolutely essential for the absorption of fructose in intestine and generation of fructose-induced hypertension J Am Soc Nephrol, 18 , 381A


Bishop J, Werlander J, Lee H, Wronski J, Amlal H, Handlogten M, Dweiner I 2008. Role of estrogen in basal renal ammonia metabolism J Am Soc Nephrol, 18 , 347A


Shaikh A, Soleimani M, Amlal H 2008. Estrogen upregulates the Na+-glutamine contransporter (SN1) but does not stimulate ammoniagenesis in ovariectomized rat kidney J Am Soc Nephrol, 18 , 347A


Amlal H 2007. Acid loading downregulates the expression of Claudin-2 and Claudin-10 in the proximal tubule of rat kidney J Am Soc Nephrol, 18 , 116A


Amlal H, Levi M, Faroqui S 2007. Estrogen downregulates the expression of proximal tubule Na-Pi cotransporter (NaPi-lia) and causes phosphaturia in ovariectomized rats J Am Soc Nephrol, 18 , 56A


Singh A, Amlal H, Haas P, Dringenberg U, Fussell S, Barone S, Engelhardt R, Zuo J, Seidler U, Soleimani M 2007. The chloride/base exchanger Slc26a6 (PAT1) plays an essential role in the pathogenesis of fructose-induced hypertension J Am Soc Nephrol, 18 , 598A


Amlal H, Barone S, Soleimani M 2006. Regulation of pendrin in water deprivation and sodium depletion J Am Soc Nephrol, 17 , 473A


Amlal H, Faroqui S, Khakwani H 2006. Molecular mechanisms of increased ammoniagenesis in the kidney proximal tubule of potassium-deprived rats J Am Soc Nephrol, 17 , 533A


Amlal H, Khakwani H 2006. Distribution of glutamine transporters in the kidney and upregulation of ASCT2 in metabolic acidosis J Am Soc Nephrol, 17 , 817A


Barone S, Amlal H, Wang Z, Soleimani M 2006. Differential regulation of the CI-/base exchanger SLC26A6 and the Na+/H+ exchanger NHE3 in the proximal tubule and the CI/base exchangers AE1 and SLC26A7 in the OMCD in potassium depletion J Am Soc Nephrol, 17 , 579A


Amlal H, Chaudry F, Faroqui S 2005. Coordinated upregulation of Na+-glutamine cotransporter (SN1) and ammoniagenesis enzymes in the kidney cortex of potassium-deprived rats J Am Soc Nephrol, 16 , 125A


Amlal H, Faroqui S 2005. Escape from hypercalcemia-induced polyuria and urinary concentrating defect in ovariectomized rats J Am Soc Nephrol, 16 , 130A


Amlal H, Wang Z, Barone S, Soleimani M 2005. Compensatory upregulation of ion transporters in the kidney proximal tubule of Slc26a6 null mice J Am Soc Nephrol, 16 , 351A


Faroqui S, Sheriff S, Soleimani M, Amlal H 2005. High protein diet upregulates the Na+-K+-2Cl cotransporter (NKCC2 or BSC1) in the medullary thick ascending limb of rat kidney J Am Soc Nephrol, 16 , 348A


Amlal H, Faroqui S 2004. Metabolic acidosis downregulates the apical calcium channel (ECaC 1) and basolateral Na+/Ca++ exchanger (NCX1) in rat kidney and causes hypercaliuria J Am Soc Nephrol, 15 , 312A


Amlal H, Faroqui S 2004. Metabolic acidosis has dual effect on sodium handling by rat kidney J Am Soc Nephrol, 15 , 312A


Amlal H, Faroqui S, Barone S, Petrovic S, Soleimani M 2004. Effect of chronic vasopressin treatment on acid-base balance and acid-base transporters in the collecting duct J Am Soc Nephrol, 15 , 72A


Petrovic A, Amlal H, Ma L, Miskin A, Barone S, Soleimani M 2004. Effects of vasopressin and aldosterone on Slc26A7 in rat kidney J Am Soc Nephrol, , 77A


Amlal H, Sheriff S, Soleiman M, Wilke C 2003. Downregulation of medullary thick ascending limb (mTAL) apical Na+-dependent transporters and collecting duct (CD) water channels in metabolic alkalosis J Am Soc Nephrol, 14 , 310A


Amlal H, Soleimani M, Wilke C 2003. Acetazolamide blocks the acidosis-induced upregulation of ammoniagenesis and gluconeogenesis enzymes in mouse kidney J Am Soc Nephrol, 14 , 305A


Amlal H, Wilke C 2002. Effects of fasting on adrenal steroid metabolism: role in Na+ retention by the kidney J Am Soc Nephrol, 13 , 76A


Amlal H, Wilke C 2002. Effects of food deprivation on renal apical Na+-dependent transporters J Am Soc Nephrol, 13 , 279A


Quian C, Soleimani M, Amlal H 2001. Thyroparathyroidectomy (TPTX) prevents the downregulation of proximal tubule (PT) apical Na+/H+ exchanger (NHE-3) and the basolateral Na+:HCO3- contransporter (NBC-1) by NaCl loading J Am Soc Nephrol, 12 , 1A


Quian C, Soleimani M, Amlal H 2001. Dual effect of long-term fasting on urinary concentrating ability in rat kidney J Am Soc Nephrol, 12 , 14A


Quian C, Soleimani M, Amlal H 2001. Possible role of corticosterone in short-term (24hrs) fasting-induced polyuria and downregulation of AQP2 in rat kidney J Am Soc Nephrol, 12 , 14A


Amlal H, Chen Q, Soleimani M 2000. Coordinated regulation of basolateral Na+: HCO3-cotransporter NBC-1 and apical Na+/H+ exchanger NHE-3 in bicarbonate loading J Am Soc Nephrol, 11 , 1A


Amlal H, Chen Q, Soleimani M 2000. Effect of adrenalectomy and saline on fasting-induced urinary concentrating defect in rat J Am Soc Nephrol, 11 , 13A


Amlal H, Chen Q, Soleimani M, 2000. Metabolic acidosis upregulates the expression of Aquaporin-2 (AQP-2) water channel in rat kidney J Am Soc Nephrol, 11 , 13A


Amlal H, Ledoussal C, Shull G, Soleimani M 2000. Urinary concentrating defect in NHE-3 null mice J Am Soc Nephrol, 11 , 12A


Greeley T, Wang Z, Amlal H, Soleimani M 2000. Increased expression of rat renal colonic H-K-ATPase (HKAc) in fasting and bicarbonate loading J Am Soc Nephrol, 2000 11,


Amlal H, Habo K, Soleimani M 1999. Potassium deprivation induces the expression of the basolateral Na+:HCO3 cotransporter (NBC-1) in medullary thick ascending limb (mTAL) J Am Soc Nephrol, 10 , 1A


Amlal H, Habo K, Soleimani M 1999. Coordinated downregulation of apical Na+-K+-2Cl-(BSC-1) and Aquaporin (AQP-2) in chloride depletion alkalosis (CDA): a basis for alkalosis-induced polyuria J Am Soc Nephrol, 10 , 12A


Amlal H, Habo K, Wang Z, Soleimani M 1999. Downregulation of Aquaporin 2 (AQP-2) in fasting rats: a basis for nephrogenic diabetes insipidus (DI) in starvation J Am Soc Nephrol, 10 , 12A


Burnham C, Shumaker H, Amlal H, Soleimani M 1999. Magnesium depletion increases the expression of colonic H+-K+ ATPase in rat kidney: A basis for metabolic alkalosis in hypomagnesaemia J Am Soc Nephrol, 10 , 2A


Nakamura S, Spicer Z, Amlal H, Shull G, Galla J, Soleimani M 1999. Renal NH4+ secretion in colonic H+K+-ATPase (HKAc) deficient mouse: effect of K+ deprivation J Am Soc Nephrol, 10 , 7A


Ali R, Amlal H, Burnham C, Soleimani M 1998. The effect of glucocorticoids on the expression and activity of the basolateral Na+-HCO3 cotransport (NBC-1) in renal proximal tubule J Am Soc Nephrol, 9 , 1A


Amlal H, Burnham C, Wang Z, Soleimani M 1998. Regulation of cloned human Na+-HCO3-cotransport (NBC-1) by protein kinase pathways J Am Soc Nephrol, 9 , 2A


Amlal H, Burnham E, Soleimani M 1998. Potassium depletion upregulates the expression of the basolateral Na+-HCO3-cotransporter (NBC-1) in rat renal nephron segments J Am Soc Nephrol, 9 , 2A


Amlal H, Kishore B, Krane C, Soleimani M 1998. Coordinated downregulation of apical Na+-K+2Cl cotransporter and aquaporin2 (AQP-2) in potassium depletion (KD): A basis for nephrogenic diabetes insipidus (DI) J Am Soc Nephrol, 9 , 15A


Nakamura S, Amlal H, Galla J, Soleimani M 1998. Colonic H+-K+-ATPase is induced and mediates increased HCO3-reabsorption in inner medullary collecting duct (IMCDt) in potassium depletion J Am Soc Nephrol, 9 , 41A


Nakamura S, Amlal P, Schulteis P, Galls J, Soleimani M 1998. Compensatory HCO3-reabsorption in the distal nephron of NHE-3 deficient mouse J Am Soc Nephrol, 9 , 10A


Amlal H, Soleimani M 1997. Induction of colonic H+-K+-ATPase 9cHKA) and upregulation of NHE-3 in proximal colon: compensatory mechanisms for Na+ and HCO3-reabsorption in diarrhea J Am Soc Nephrol, 8 , 2A


Amlal H, Wang Z, Burnham C, Soleimani M 1997. A cloned Na+:HCO3 can function in Na+:OH cotransport mode J Am Soc Nephrol, 8 , 2A


Amlal H, Wang Z, Soleimani M 1997. Potassium depletion downregulates apical chloride-absorbing transporters in rat kidney J Am Soc Nephrol, 8 , 28A


Burnham C, Amlal H, Wang Z, Shull G, Soleimani M 1997. Molecular cloning and functional expression of a human Na+:HCO3 cotransporter J Am Soc Nephrol, 8 , 3A


Nakamura S, Amlal H, Soleimani M, Galla J 1997. Mechanism of HCO3 reabsorption in the perfused mouse OMCD and IMCD J Am Soc Nephrol, 8 , 8A


Amlal H, Soleimani M 1996. Activation of H+-ATPase by hypotonicity: A novel regulatory mechanism for H+ transport inner medulla J Am Soc Nephrol, 7 , 1250


Amlal H, Soleimani M 1996. A unique ammonium carrying transporter in the kidney inner medulla J Am Soc Nephrol, 7 , 1250


Amlal H, Soleimani M 1996. Induction of H+-ATPase by lethal acid stress: A mechanism for survival and accelerated growth in cultured inner medullary collecting duct cells J Am Soc Nephrol, 7 , 1250


Bichara M, Amlal H, Laghmani P, Borensztein P, Paillard M 1995. Control of NHE-3 transport activity by PKA, PKC, and arachidonic acid in MTAL cells J Am Soc Nephrol, 6 , 332


Amlal H, Vernimmen C, Legoff C, Paillard M, Bichara M 1993. Control of Na+-K+ (NH4+)-2Cl cotransport by angiotensin II (AII)-active transduction pathways in medullary thick ascending limb cells J Am Soc Nephrol, 4 , 862


Bichara M, Amlal H, Mary F, Paillard M 1991. NH4+/HCO3 - cotransport in medullar thick ascending limb (MTAL) J Am Soc Nephrol, 2 , 696