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Department of Internal Medicine

Immunology, Allergy and Rheumatology

Photo of  William Ridgway, MD

William Ridgway, MD

Professor of Medicine, Division Director

Education/Credentials
  • Bachelor's Degree: Haverford College
  • Post-baccalaureate: Bryn Mawr College
  • Medical Degree: University of Rochester
  • Residency : Stanford University Hospital
  • Clinical Fellowship: Stanford University Hospital
  • Physician Postdoctoral Fellowship : Howard Hughes Medical Institute
  • Research Fellowship: Stanford University School of Medicine
  • Research Associate : Stanford University School of Medicine

Board Certifications & Licenses
  • American Board of Internal Medicine 09/22/1993
  • American Board of Internal Medicine (Rheumatology) 10/23/2008
Contact Information
  • Health Professions Building
  • 3255 Eden Ave
  • Suite 350
  • Cincinnati, Ohio 45267-0563
  • Office 513-558-4701
  • Fax 513-558-3799
  • Email william.ridgway@uc.edu

Peer Reviewed Publications

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Forsberg, Matthew H; Ciecko, Ashley E; Bednar, Kyle J; Itoh, Arata; Kachapati, Kritika; Ridgway, William M; Chen, Yi-Guang 2017. CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. Journal of immunology (Baltimore, Md. : 1950), 198 10, 3857-3868

Itoh, Arata; Ridgway, William M 2017. Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes. ImmunoTargets and therapy, 6 , 31-38

Ma, Hong-Di; Ma, Wen-Tao; Liu, Qing-Zhi; Zhao, Zhi-Bin; Liu, Mu-Zi-Ying; Tsuneyama, Koichi; Gao, Jin-Ming; Ridgway, William M; Ansari, Aftab A; Gershwin, M Eric; Fei, Yun-Yun; Lian, Zhe-Xiong 2017. Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8(+) T cell activation. Journal of autoimmunity, 78 , 19-28

Yang, G-X; Sun, Y; Tsuneyama, K; Zhang, W; Leung, P S C; He, X-S; Ansari, A A; Bowlus, C; Ridgway, W M; Gershwin, M E 2016. Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice. Clinical and experimental immunology, 185 2, 154-64

Yang, Jing-Bo; Wang, Yin-Hu; Yang, Wei; Lu, Fang-Ting; Ma, Hong-Di; Zhao, Zhi-Bin; Jia, Yan-Jie; Tang, Wei; Tsuneyama, Koichi; Ridgway, William M; Gershwin, M Eric; Lian, Zhe-Xiong 2016. Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy. Journal of autoimmunity, 66 , 108-17

Bednar, Kyle J; Tsukamoto, Hiroki; Kachapati, Kritika; Ohta, Shoichiro; Wu, Yuehong; Katz, Jonathan D; Ascherman, Dana P; Ridgway, William M 2015. Reversal of New-Onset Type 1 Diabetes with an agonistic TLR4/MD-2 Monoclonal Antibody. Diabetes, ,

Wang, Yin-Hu; Yang, Wei; Yang, Jing-Bo; Jia, Yan-Jie; Tang, Wei; Gershwin, M Eric; Ridgway, William M; Lian, Zhe-Xiong 2015. Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis. Journal of autoimmunity, 59 , 26-37

Bednar, Kyle J; Ridgway, William M 2014. Targeting innate immunity for treatment of type 1 diabetes. Immunotherapy, 6 12, 1239-42

Huang, Wenting; Kachapati, Kritika; Adams, David; Wu, Yuehong; Leung, Patrick S C; Yang, Guo-Xiang; Zhang, Weici; Ansari, Aftab A; Flavell, Richard A; Gershwin, M Eric; Ridgway, William M 2014. Murine autoimmune cholangitis requires two hits: Cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. Journal of autoimmunity, ,

Ridgway, William M 2014. A new tool for dissecting genetic control of type 1 diabetes. Diabetes, 63 1, 56-8

Ridgway, William M; Gershwin, M Eric 2014. Prometheus unbound: NKT cells inhibit hepatic regeneration. Hepatology (Baltimore, Md.), 60 4, 1133-5

Wang, Jinjun; Yang, Guo-Xiang; Tsuneyama, Koichi; Gershwin, M Eric; Ridgway, William M; Leung, Patrick S C 2014. Animal models of primary biliary cirrhosis. Seminars in liver disease, 34 3, 285-96

Yang, Wei; Yao, Yuan; Yang, Yan-Qing; Lu, Fang-Ting; Li, Liang; Wang, Yin-Hu; Nakajima, Takahiko; Tsuneyama, Koichi; Ridgway, William M; Gershwin, M Eric; Lian, Zhe-Xiong 2014. Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2R? deleted mice. PloS one, 9 8, e105351

Kachapati, Kritika; Bednar, Kyle J; Adams, David E; Wu, Yuehong; Mittler, Robert S; Jordan, Michael B; Hinerman, Jennifer M; Herr, Andrew B; Ridgway, William M 2013. Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice. Journal of autoimmunity, 47 , 94-103

Kachapati, Kritika; Adams, David E; Wu, Yuehong; Steward, Charles A; Rainbow, Daniel B; Wicker, Linda S; Mittler, Robert S; Ridgway, William M 2012. The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. Journal of immunology (Baltimore, Md. : 1950), 189 10, 5001-15

Kachapati, Kritika; Adams, David; Bednar, Kyle; Ridgway, William M 2012. The non-obese diabetic (NOD) mouse as a model of human type 1 diabetes. Methods in molecular biology (Clifton, N.J.), 933 , 3-16

Mohammed, Javid P; Fusakio, Michael E; Rainbow, Daniel B; Moule, Carolyn; Fraser, Heather I; Clark, Jan; Todd, John A; Peterson, Laurence B; Savage, Paul B; Wills-Karp, Marsha; Ridgway, William M; Wicker, Linda S; Mattner, Jochen 2011. Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity. Journal of immunology (Baltimore, Md. : 1950), 187 1, 337-49