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The primary objective of the University of Cincinnati (UC) Center for Cardiovascular Research (CCR) is the development of groundbreaking collaborative research programs for complex cardiovascular diseases by systematic integration of basic and translational studies, along with training, across disciplines, departments, and other institutions, both national and international.
in the understanding, prevention, and treatment of cardiovascular disease.”
A. a full-time editorial specialist (100%) for both grants and publications,
B. a finance administrator (10%) responsible for managing CCR budgeting, finance, and approvals, and
C. an administrative assistant (50%) responsible for handling general office and administrative tasks in support of the Executive and Associate Directors. He/she will be responsible for coordinating communications, scheduling, and managing the CCR database and website, among other duties still TBD.
D. List of external organizations expected to participate: The CCR will work closely with faculty members of the COM, as well as its institutes and centers, such as UC Gardner Neuroscience and University of Cincinnati Cancer Center, CCHMC Heart Institute, and members of the Cincinnati American Heart Association. In addition, the the CCR will expand its collaboration with local hospitals to support the UC Heart Bank and clinical studies, as well as various heart institutes within Ohio, all in the spirit of networking and collaborating inside and outside the campus, as noted above.
E. Draft charter: The CCR aims to integrate research and training activities to advance bench-to-bedside patient care and personalized medicine. F. Governance Draft charter: The CCR aims to integrate research and training activities to advance bench-to-bedside patient care and personalized medicine.
Year 1 (Sep 2023 to Aug 2024): Upon approval of the CCR by the UC COM Dean, an Executive Director will be appointed, and a tentative budget will be drawn up (see Figure 1). During the first six months, the newly appointed leadership, Executive Director, will focus on generating an itemized budget by coordinating with the Dean’s Office and the current Chief Financial Officer (CFO) of the COM (see Figure 2). Announcements, name changes, and website development and updates will be performed during this period with help from the newly hired Administrative Assistant. The CVC building will be renamed as the CCR building, and necessary renovations will be initiated by bringing together the collective efforts of cardiovascular colleagues currently housed in the CVC building. The Executive Director will oversee all changes and provide progress reports in a timely manner to the Dean. It should be noted that establishment of CCR at operational level is essential for the renewal of our NIH R38 and AHA SURF grants and our ability to apply for new training grants and National Organization for Rare Disorders (NORD) funding opportunities, as spearheaded by Dr. McCormack. We will immediately submit a proposal to train a new group of undergraduate students for the summer program (AHA-SURF) since the Sep 2023 deadline is approaching.
The Executive Director will work with the UC COM Dean, Department Chairs of COM, and Co-Directors of the Cincinnati Children’s Heart Institute to ensure alignment with the mission and vision of the CCR. A strategic plan addressing the expectations of all stakeholders of CCR will be finalized. The key accountabilities are as follows:
In Year 1, significant efforts will be directed toward obtaining extramural funding through individual project proposals, career development training grants, instrument proposal requests, and center grants. Notably, CCR will be charged with installing mechanisms to market and publicize the center’s activities, in part to secure funding from industrial sources and foundations. The newly hired grant writer will provide direct support for center-based grant applications, including, for example, training and equipment grants.
A key proposal involves a collective call for a nomination to apply for a program project grant (PPG) from the College of Medicine. An open announcement will be sent out to invite three to four established members of the COM and CCHMC to jointly apply for a PPG in 2025. We will provide intramural funding support in the amount of $150,000 to $250,000 as seed money to collect preliminary data and submit the proposal.
Year 2 (Sep 2024 to Aug 2025): In the second year, we expect to expand upon our operational CCR nucleus at its one-year anniversary. Thus, during Year 2, we expect to broaden the interdisciplinary scope of our research programs, goals, cores and projects with a more mature organizational hierarchy and more precisely defined roles and responsibilities.
During Year 2, CCR administrators will work with the UC Foundation to initiate promotional and fundraising activities. CCR administrators will also coordinate with COM Department Chairs to jointly recruit faculty members for CCR with a cost center to provide long-term sustainability. G. Recruitment Plan Cardiovascular researchers at UC will be solicited by email, announcements, and news releases to apply as CCR founding members. A standard reporting template will be established to define the qualifications and expectations for CCR membership. Faculty will be expected to represent the Center by including its name in respective publications and presentations. Faculty will participate in monthly research meetings and presentations to explore potential research collaborations and joint research studies. Faculty will engage in joint mentoring and training the next generation of cardiovascular researchers. Faculty will collaborate on the submission of training grants, center grants, and larger PPG and U01 grants available at the time from NIH NHLBI. Annually, faculty evaluations will be performed by collecting specific information relevant to publications, including those naming the CCR, as well as the number of joint grants, collaborations, and mentorships.
H. Financial and Administrative Commitments: The administrative cost of the Center will be initially supported by the Dean of UC COM. Funds will also be earmarked for seminars and similar activities. At least two annual Requests for Applications (RFAs) ($50k each) will be made to promote internal collaborations, generate preliminary data for grants, as well a sponsor early career activities, travels, and attendance at seminars, both locally and nationally.
I. Statements for external funding: The COM has a core of early- and mid-career investigators with ongoing funding support and established collaborations. These scientists could easily serve as the Center’s core for joint grant submissions, such as those noted above.
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Cardiovascular Center231 Albert Sabin WayPO Box 670542Cincinnati, OH 45267-0542
Mail Location: 0542