Today is Thursday, Apr. 19, 2018

Department of

Environmental Health

Photo of  Mario Medvedovic, PhD

Mario Medvedovic, PhD

Professor and Director, Division of Biostatistics and Bioinformatics

  • Master's Degree: University of Zagreb
  • Master's Degree: Bowling Green State University
  • Doctoral Degree: University of Cincinnati

Research/Clinical Interests

Bioinformatics, Biostatistics and Biomedical Data Science

Contact Information
  • Kettering Laboratory
  • Room 110
  • 160 Panzeca Way
  • Cincinnati, Ohio 45267
  • Office 513-558-8564
  • Email

Peer Reviewed Publications

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Carreira, Vinicius S; Fan, Yunxia; Wang, Qing; Zhang, Xiang; Kurita, Hisaka; Ko, Chia-I; Naticchioni, Mindi; Jiang, Min; Koch, Sheryl; Medvedovic, Mario; Xia, Ying; Rubinstein, Jack; Puga, Alvaro 2015. Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes. Toxicological sciences : an official journal of the Society of Toxicology, 147 2, 425-35

Cheng, Xin-Hua; Black, Markaisa; Ustiyan, Vladimir; Le, Tien; Fulford, Logan; Sridharan, Anusha; Medvedovic, Mario; Kalinichenko, Vladimir V; Whitsett, Jeffrey A; Kalin, Tanya V 2014. SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene. PLoS genetics, 10 9, e1004656

Chen, Jing; Hu, Zhen; Phatak, Mukta; Reichard, John; Freudenberg, Johannes M; Sivaganesan, Siva; Medvedovic, Mario 2013. Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules. PLoS computational biology, 9 9, e1003198

Ma, Li; Tao, Yongzhen; Duran, Angeles; Llado, Victoria; Galvez, Anita; Barger, Jennifer F; Castilla, Elias A; Chen, Jing; Yajima, Tomoko; Porollo, Aleksey; Medvedovic, Mario; Brill, Laurence M; Plas, David R; Riedl, Stefan J; Leitges, Michael; Diaz-Meco, Maria T; Richardson, Adam D; Moscat, Jorge 2013. Control of nutrient stress-induced metabolic reprogramming by PKC? in tumorigenesis. Cell, 152 3, 599-611

Shioda, Toshi; Rosenthal, Noël F; Coser, Kathryn R; Suto, Mizuki; Phatak, Mukta; Medvedovic, Mario; Carey, Vincent J; Isselbacher, Kurt J 2013. Expressomal approach for comprehensive analysis and visualization of ligand sensitivities of xenoestrogen responsive genes. Proceedings of the National Academy of Sciences of the United States of America, 110 41, 16508-13

Freudenberg, Johannes M; Sivaganesan, Siva; Wagner, Michael; Medvedovic, Mario 2010. A semi-parametric Bayesian model for unsupervised differential co-expression analysis. BMC bioinformatics, 11 , 234

Medvedovic, M; Gear, R; Freudenberg, J M; Schneider, J; Bornschein, R; Yan, M; Mistry, M J; Hendrix, H; Karyala, S; Halbleib, D; Heffelfinger, S; Clegg, D J; Anderson, M W 2009. Influence of fatty acid diets on gene expression in rat mammary epithelial cells. Physiological genomics, 38 1, 80-8

Sartor, Maureen A; Leikauf, George D; Medvedovic, Mario 2009. LRpath: a logistic regression approach for identifying enriched biological groups in gene expression data. Bioinformatics (Oxford, England), 25 2, 211-7

Liu, Xiangdong; Jessen, Walter J; Sivaganesan, Siva; Aronow, Bruce J; Medvedovic, Mario 2007. Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data. BMC bioinformatics, 8 , 283

Liu, X; Sivaganesan, S; Yeung, K Y; Guo, J; Bumgarner, R E; Medvedovic, Mario 2006. Context-specific infinite mixtures for clustering gene expression profiles across diverse microarray dataset. Bioinformatics (Oxford, England), 22 14, 1737-44

Medvedovic, Mario; Tomlinson, Craig R; Call, Mindy K; Grogg, Matthew; Tsonis, Panagiotis A 2006. Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation. Molecular vision, 12 , 422-40

Nikiforova, M N; Stringer, J R; Blough, R; Medvedovic, M; Fagin, J A; Nikiforov, Y E 2000. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science (New York, N.Y.), 290 5489, 138-41