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Department of

Environmental Health

Photo of Susan Kasper, PhD

Susan Kasper, PhD

Associate Professor, Department of Environmental Health, UC College of Medicine

  • B.Sc. Honours: University of Manitoba
  • M.S.: University of Manitoba
  • Ph.D.: University of Manitoba

Contact Information
  • Department of Environmental Health
  • Kettering Laboratory
  • Office 513-558-2126
  • Email

Peer Reviewed Publications

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Zhou, Jian; Giridhar, Premkumar Vummidi; Kasper, Susan; Papautsky, Ian 2014. Modulation of rotation-induced lift force for cell filtration in a low aspect ratio microchannel. Biomicrofluidics, 8 4, 044112

Cai, Yuqi; Balli, David; Ustiyan, Vladimir; Fulford, Logan; Hiller, Andrea; Misetic, Vinko; Zhang, Yufang; Paluch, Andrew M; Waltz, Susan E; Kasper, Susan; Kalin, Tanya V 2013. Foxm1 expression in prostate epithelial cells is essential for prostate carcinogenesis. The Journal of biological chemistry, 288 31, 22527-41

Zhou, Jian; Giridhar, Premkumar Vummidi; Kasper, Susan; Papautsky, Ian 2013. Modulation of aspect ratio for complete separation in an inertial microfluidic channel. Lab on a chip, 13 10, 1919-29

Zhou, Jian; Kasper, Susan; Papautsky, Ian 2013. Enhanced size-dependent trapping of particles using microvortices. Microfluidics and nanofluidics, 15 5,

Williams, Karin; Ghosh, Ritwik; Giridhar, Premkumar Vummidi; Gu, Guangyu; Case, Thomas; Belcher, Scott M; Kasper, Susan 2012. Inhibition of stathmin1 accelerates the metastatic process. Cancer research, 72 20, 5407-17

Liu, June; Pascal, Laura E; Isharwal, Sudhir; Metzger, Daniel; Ramos Garcia, Raquel; Pilch, Jan; Kasper, Susan; Williams, Karin; Basse, Per H; Nelson, Joel B; Chambon, Pierre; Wang, Zhou 2011. Regenerated luminal epithelial cells are derived from preexisting luminal epithelial cells in adult mouse prostate. Molecular endocrinology (Baltimore, Md.), 25 11, 1849-57

Zhang, JianFeng; Gao, Nan; DeGraff, David J; Yu, Xiuping; Sun, Qian; Case, Thomas C; Kasper, Susan; Matusik, Robert J 2010. Characterization of cis elements of the probasin promoter necessary for prostate-specific gene expression. The Prostate, 70 9, 934-51

Chaurand, Pierre; Rahman, Mohammad A; Hunt, Tamela; Mobley, James A; Gu, Guangyu; Latham, Joey C; Caprioli, Richard M; Kasper, Susan 2008. Monitoring mouse prostate development by profiling and imaging mass spectrometry. Molecular & cellular proteomics : MCP, 7 2, 411-23

Ghosh, Ritwik; Gu, Guangyu; Tillman, Erin; Yuan, Jialing; Wang, Yongqing; Fazli, Ladan; Rennie, Paul S; Kasper, Susan 2007. Increased expression and differential phosphorylation of stathmin may promote prostate cancer progression. The Prostate, 67 10, 1038-52

Gipp, Jerry; Gu, Guangyu; Crylen, Curtis; Kasper, Susan; Bushman, Wade 2007. Hedgehog pathway activity in the LADY prostate tumor model. Molecular cancer, 6 , 19

Gu, Guangyu; Yuan, Jialing; Wills, Marcia; Kasper, Susan 2007. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer research, 67 10, 4807-15

Tillman, J Erin; Yuan, Jialing; Gu, Guangyu; Fazli, Ladan; Ghosh, Ritwik; Flynt, Alex S; Gleave, Martin; Rennie, Paul S; Kasper, Susan 2007. DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. Cancer research, 67 10, 4630-7

Pitkänen-Arsiola, Tiina; Tillman, J Erin; Gu, Guangyu; Yuan, Jialing; Roberts, Richard L; Wantroba, Marcus; Coetzee, Gerhard A; Cookson, Michael S; Kasper, Susan 2006. Androgen and anti-androgen treatment modulates androgen receptor activity and DJ-1 stability. The Prostate, 66 11, 1177-93

Wang, Yongqing; Kasper, Susan; Yuan, Jialing; Jin, Ren Jie; Zhang, Jianfeng; Ishii, Kenichiro; Wills, Marcia L; Hayward, Simon W; Matusik, Robert J 2006. Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer. Laboratory investigation; a journal of technical methods and pathology, 86 10, 1074-88

Jin, Ren Jie; Wang, Yongqing; Masumori, Naoya; Ishii, Kenichiro; Tsukamoto, Taiji; Shappell, Scott B; Hayward, Simon W; Kasper, Susan; Matusik, Robert J 2004. NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice. Cancer research, 64 15, 5489-95

Masumori, Naoya; Tsuchiya, Karen; Tu, William H; Lee, Charles; Kasper, Susan; Tsukamoto, Taiji; Shappell, Scott B; Matusik, Robert J 2004. An allograft model of androgen independent prostatic neuroendocrine carcinoma derived from a large probasin promoter-T antigen transgenic mouse line. The Journal of urology, 171 1, 439-42

Zhang, JianFeng; Gao, Nan; Kasper, Susan; Reid, Kimberly; Nelson, Colleen; Matusik, Robert J 2004. An androgen-dependent upstream enhancer is essential for high levels of probasin gene expression. Endocrinology, 145 1, 134-48

Zhang, Ye; Yu, Jiang; Unni, Emmanual; Shao, Tsang C; Nan, Bicheng; Snabboon, Thiti; Kasper, Susan; Andriani, Francesca; Denner, Larry; Marcelli, Marco 2002. Monogene and polygene therapy for the treatment of experimental prostate cancers by use of apoptotic genes bax and bad driven by the prostate-specific promoter ARR(2)PB. Human gene therapy, 13 17, 2051-64

Kasper, S; Rennie, P S; Bruchovsky, N; Sheppard, P C; Cheng, H; Lin, L; Shiu, R P; Snoek, R; Matusik, R J 1994. Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene. The Journal of biological chemistry, 269 50, 31763-9

Leite, V; Vrontakis, M E; Kasper, S; Friesen, H G 1993. Bromocriptine inhibits galanin gene expression in the rat pituitary gland. Molecular and cellular neurosciences, 4 5, 418-23

Kasper, S; Popescu, R A; Torsello, A; Vrontakis, M E; Ikejiani, C; Friesen, H G 1992. Tissue-specific regulation of vasoactive intestinal peptide messenger ribonucleic acid levels by estrogen in the rat. Endocrinology, 130 4, 1796-801

Fink, J S; Verhave, M; Kasper, S; Tsukada, T; Mandel, G; Goodman, R H 1988. The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer. Proceedings of the National Academy of Sciences of the United States of America, 85 18, 6662-6

Kasper, S; Friesen, H G 1986. Human pituitary tissue secretes a potent growth factor for chondrocyte proliferation. The Journal of clinical endocrinology and metabolism, 62 1, 70-6

Rowe, J M; Kasper, S; Shiu, R P; Friesen, H G 1986. Purification and characterization of a human mammary tumor-derived growth factor. Cancer research, 46 3, 1408-12

Kasper, S; Worsley, I G; Rowe, J M; Shiu, R P; Friesen, H G 1982. Chondrocyte growth factor from the human pituitary gland. The Journal of biological chemistry, 257 9, 5226-30

Kendig, Eric L; Buesing, Dana R; Christie, Susie M; Cookman, Clifford J; Gear, Robin B; Hugo, Eric R; Kasper, Susan N; Kendziorski, Jessica A; Ungi, Kevin R; Williams, Karin; Belcher, Scott M . Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17?-ethinyl estradiol in CD1 mice. International journal of toxicology, 31 6, 537-50

Tu, William H; Thomas, Tania Z; Masumori, Naoya; Bhowmick, Neil A; Gorska, Agnieszka E; Shyr, Yu; Kasper, Susan; Case, Tom; Roberts, Richard L; Shappell, Scott B; Moses, Harold L; Matusik, Robert J . The loss of TGF-beta signaling promotes prostate cancer metastasis. Neoplasia (New York, N.Y.), 5 3, 267-77