Today is Tuesday, Oct. 16, 2018

Department of

Environmental Health

Photo of  Lynne Haber, PhD

Lynne Haber, PhD

Associate Professor, Adjunct; Senior Toxicologist

Education/Credentials
  • PhD: Massachusetts Institute of Technology
  • BS: University of California at Los Angeles

Board Certifications & Licenses
  • Diplomate, American Board of Toxicology (DABT) American Board of Toxicology, 2004, recertified 2009, 2014
Contact Information

Peer Reviewed Publications

Display All

Felter, Susan P; Foreman, Jennifer E; Boobis, Alan; Corton, J Christopher; Doi, Adriana M; Flowers, Lynn; Goodman, Jay; Haber, Lynne T; Jacobs, Abigail; Klaunig, James E; Lynch, Angela M; Moggs, Jonathan; Pandiri, Arun 2018. Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action. Regulatory toxicology and pharmacology : RTP, 92 , 1-7

Haber, Lynne T; Dourson, Michael L; Allen, Bruce C; Hertzberg, Richard C; Parker, Ann; Vincent, Melissa J; Maier, Andrew; Boobis, Alan R 2018. Benchmark dose (BMD) modeling: current practice, issues, and challenges. Critical reviews in toxicology, 48 5, 387-415

Haber, Lynne T; Bates, Hudson K; Allen, Bruce C; Vincent, Melissa J; Oller, Adriana R 2017. Derivation of an oral toxicity reference value for nickel. Regulatory toxicology and pharmacology : RTP, 87 Suppl 1 , S1-S18

Manjanatha, Mugimane G; Shelton, Sharon D; Chen, Ying; Parsons, Barbara L; Myers, Meagan B; McKim, Karen L; Gollapudi, B Bhaskar; Moore, Nigel P; Haber, Lynne T; Allen, Bruce; Moore, Martha M 2017. Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations. Environmental and molecular mutagenesis, 58 3, 122-134

Allen, Bruce C; Vincent, Melissa J; Liska, DeAnn; Haber, Lynne T 2016. Meta-regression analysis of the effect of trans fatty acids on low-density lipoprotein cholesterol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 98 Pt B, 295-307

Haber, Lynne T; Sandhu, Reena; Li-Muller, Angela; Mohapatra, Asish; Petrovic, Sanya; Meek, M E Bette 2016. Framework for human health risk assessment of non-cancer effects resulting from short-duration and intermittent exposures to chemicals. Journal of applied toxicology : JAT, 36 9, 1077-89

Reichard, John F; Haber, Lynne T 2016. Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 98 Pt B, 282-294

Shatkin, J A; Ong, Kimberly J; Beaudrie, Christian; Clippinger, Amy J; Hendren, Christine Ogilvie; Haber, Lynne T; Hill, Myriam; Holden, Patricia; Kennedy, Alan J; Kim, Baram; MacDonell, Margaret; Powers, Christina M; Sharma, Monita; Sheremeta, Lorraine; Stone, Vicki; Sultan, Yasir; Turley, Audrey; White, Ronald H 2016. Advancing Risk Analysis for Nanoscale Materials: Report from an International Workshop on the Role of Alternative Testing Strategies for Advancement. Risk analysis : an official publication of the Society for Risk Analysis, 36 8, 1520-37

Banda, Malathi; McKim, Karen L; Haber, Lynne T; MacGregor, Judith A; Gollapudi, B Bhaskar; Parsons, Barbara L 2015. Quantification of Kras mutant fraction in the lung DNA of mice exposed to aerosolized particulate vanadium pentoxide by inhalation. Mutation research. Genetic toxicology and environmental mutagenesis, 789-790 , 53-60

DeBord, D Gayle; Burgoon, Lyle; Edwards, Stephen W; Haber, Lynne T; Kanitz, M Helen; Kuempel, Eileen; Thomas, Russell S; Yucesoy, Berran 2015. Systems Biology and Biomarkers of Early Effects for Occupational Exposure Limit Setting. Journal of occupational and environmental hygiene, , 0

Manjanatha, Mugimane G; Shelton, Sharon D; Haber, Lynne; Gollapudi, Bhaskar; MacGregor, Judith A; Rajendran, Narayanan; Moore, Martha M 2015. Evaluation of cII mutations in lung of male Big Blue mice exposed by inhalation to vanadium pentoxide for up to 8 weeks. Mutation research. Genetic toxicology and environmental mutagenesis, 789-790 , 46-52

Sweeney, Lisa M; MacCalman, Laura; Haber, Lynne T; Kuempel, Eileen D; Tran, C Lang 2015. Bayesian evaluation of a physiologically-based pharmacokinetic (PBPK) model of long-term kinetics of metal nanoparticles in rats. Regulatory toxicology and pharmacology : RTP, 73 1, 151-63

Bette Meek, M E; Bolger, Michael; Bus, James S; Christopher, John; Conolly, Rory B; Lewis, R Jeffrey; Paolini, Gregory M; Schoeny, Rita; Haber, Lynne T; Rosenstein, Amy B; Dourson, Michael L 2013. A framework for fit-for-purpose dose response assessment. Regulatory toxicology and pharmacology : RTP, 66 2, 234-40

Dourson, Michael; Becker, Richard A; Haber, Lynne T; Pottenger, Lynn H; Bredfeldt, Tiffany; Fenner-Crisp, Penelope A 2013. Advancing human health risk assessment: integrating recent advisory committee recommendations. Critical reviews in toxicology, 43 6, 467-92

Hertzberg, Richard C; Pan, Yi; Li, Ruosha; Haber, Lynne T; Lyles, Robert H; Herr, David W; Moser, Virginia C; Simmons, Jane Ellen 2013. A four-step approach to evaluate mixtures for consistency with dose addition. Toxicology, 313 2-3, 134-44

Parsons, Barbara L; Manjanatha, Mugimane G; Myers, Meagan B; McKim, Karen L; Shelton, Sharon D; Wang, Yiying; Gollapudi, B Bhaskar; Moore, Nigel P; Haber, Lynne T; Moore, Martha M 2013. Temporal changes in K-ras mutant fraction in lung tissue of big blue B6C3F? mice exposed to ethylene oxide. Toxicological sciences : an official journal of the Society of Toxicology, 136 1, 26-38

Sweeney, Lisa M; Parker, Ann; Haber, Lynne T; Tran, C Lang; Kuempel, Eileen D 2013. Application of Markov chain Monte Carlo analysis to biomathematical modeling of respirable dust in US and UK coal miners. Regulatory toxicology and pharmacology : RTP, 66 1, 47-58

Maier, Andrew; Kohrman-Vincent, Melissa; Hertzberg, Richard; Allen, Bruce; Haber, Lynne T; Dourson, Michael 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide - additional insights based on mode of action. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50 5, 1763-75

Moser, Virginia C; Padilla, Stephanie; Simmons, Jane Ellen; Haber, Lynne T; Hertzberg, Richard C 2012. Impact of chemical proportions on the acute neurotoxicity of a mixture of seven carbamates in preweanling and adult rats. Toxicological sciences : an official journal of the Society of Toxicology, 129 1, 126-34

Mwanza, Jean-Claude; Lyke, Danielle F; Hertzberg, Richard C; Haber, Lynne; Kohrman-Vincent, Melissa; Li, Ruosha; Pan, Yi; Lyles, Robert H; Simmons, Jane Ellen; Macmillan, Denise K; Zehr, R Dan; Swank, Adam E; Herr, David W 2012. Cholinesterase inhibition and depression of the photic after discharge of flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur. Neurotoxicology, 33 3, 332-46

Rhomberg, Lorenz R; Goodman, Julie E; Haber, Lynne T; Dourson, Michael; Andersen, Melvin E; Klaunig, James E; Meek, Bette; Price, Paul S; McClellan, Roger O; Cohen, Samuel M 2011. Linear low-dose extrapolation for noncancer heath effects is the exception, not the rule. Critical reviews in toxicology, 41 1, 1-19

Hack, C Eric; Haber, Lynne T; Maier, Andrew; Shulte, Paul; Fowler, Bruce; Lotz, W Gregory; Savage, Russell E 2010. A Bayesian network model for biomarker-based dose response. Risk analysis : an official publication of the Society for Risk Analysis, 30 7, 1037-51

Maier, Andrew; Kohrman-Vincent, Melissa; Parker, Ann; Haber, Lynne T 2010. Evaluation of concentration-response options for diacetyl in support of occupational risk assessment. Regulatory toxicology and pharmacology : RTP, 58 2, 285-96

Haber, Lynne T; Maier, Andrew; Kroner, Oliver L; Kohrman, Melissa J 2009. Evaluation of human relevance and mode of action for tunica vaginalis mesotheliomas resulting from oral exposure to acrylamide. Regulatory toxicology and pharmacology : RTP, 53 2, 134-49

Dourson, Michael; Hertzberg, Richard; Allen, Bruce; Haber, Lynne; Parker, Ann; Kroner, Oliver; Maier, Andy; Kohrman, Melissa 2008. Evidence-based dose-response assessment for thyroid tumorigenesis from acrylamide. Regulatory toxicology and pharmacology : RTP, 52 3, 264-89

Moore, Martha M; Heflich, Robert H; Haber, Lynne T; Allen, Bruce C; Shipp, Annette M; Kodell, Ralph L 2008. Analysis of in vivo mutation data can inform cancer risk assessment. Regulatory toxicology and pharmacology : RTP, 51 2, 151-61

Stern, Bonnie Ransom; Solioz, Marc; Krewski, Daniel; Aggett, Peter; Aw, Tar-Ching; Baker, Scott; Crump, Kenny; Dourson, Michael; Haber, Lynne; Hertzberg, Rick; Keen, Carl; Meek, Bette; Rudenko, Larisa; Schoeny, Rita; Slob, Wout; Starr, Tom 2007. Copper and human health: biochemistry, genetics, and strategies for modeling dose-response relationships. Journal of toxicology and environmental health. Part B, Critical reviews, 10 3, 157-222

Schoeny, Rita; Haber, Lynne; Dourson, Michael 2006. Data considerations for regulation of water contaminants. Toxicology, 221 2-3, 217-24

Haber, L T; Patterson, J 2005. Report of an independent peer review of an acrylonitrile risk assessment. Human & experimental toxicology, 24 10, 487-527

Lipscomb, John C; Meek, M E Bette; Krishnan, Kannan; Kedderis, Gregory L; Clewell, Harvey; Haber, Lynne 2004. Incorporation of pharmacokinetic and pharmacodynamic data into risk assessments. Toxicology mechanisms and methods, 14 3, 145-58

Maier, Andrew; Savage, Russell E; Haber, Lynne T 2004. Assessing biomarker use in risk assessment--a survey of practitioners. Journal of toxicology and environmental health. Part A, 67 8-10, 687-95

Araya, Magdalena; Chen, Bingheng; Klevay, Leslie M; Strain, J J; Johnson, LuAnn; Robson, Paula; Shi, Wei; Nielsen, Forrest; Zhu, Huigang; Olivares, Manuel; Pizarro, Fernando; Haber, Lynne T 2003. Confirmation of an acute no-observed-adverse-effect and low-observed-adverse-effect level for copper in bottled drinking water in a multi-site international study. Regulatory toxicology and pharmacology : RTP, 38 3, 389-99

Gentry, P Robinan; Hack, C Eric; Haber, Lynne; Maier, Andrew; Clewell, Harvey J 2002. An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion. Toxicological sciences : an official journal of the Society of Toxicology, 70 1, 120-39

Haber, L T; Maier, A; Gentry, P R; Clewell, H J; Dourson, M L 2002. Genetic polymorphisms in assessing interindividual variability in delivered dose. Regulatory toxicology and pharmacology : RTP, 35 2 Pt 1, 177-97

Haber, Lynne T; Maier, Andrew 2002. Scientific criteria used for the development of occupational exposure limits for metals and other mining-related chemicals. Regulatory toxicology and pharmacology : RTP, 36 3, 262-79

Haber, L T; Maier, A; Zhao, Q; Dollarhide, J S; Savage, R E; Dourson, M L 2001. Applications of mechanistic data in risk assessment: the past, present, and future. Toxicological sciences : an official journal of the Society of Toxicology, 61 1, 32-9

Haber, L T; Diamond, G L; Zhao, Q; Erdreich, L; Dourson, M L 2000. Hazard identification and dose response of ingested nickel-soluble salts. Regulatory toxicology and pharmacology : RTP, 31 2 Pt 1, 231-41

Haber, L T; Erdreicht, L; Diamond, G L; Maier, A M; Ratney, R; Zhao, Q; Dourson, M L 2000. Hazard identification and dose response of inhaled nickel-soluble salts. Regulatory toxicology and pharmacology : RTP, 31 2 Pt 1, 210-30

Haber, L T; Allen, B C; Kimmel, C A 1998. Non-cancer risk assessment for nickel compounds: issues associated with dose-response modeling of inhalation and oral exposures. Toxicological sciences : an official journal of the Society of Toxicology, 43 2, 213-29

Haber, L T; Walker, G C 1991. Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities. The EMBO journal, 10 9, 2707-15