In his research, Tesfaye B. Mersha, PhD, combines quantitative, ancestry and statistical genomics approaches to unravel genetic and non-genetic contributions to complex diseases and racial disparities in human population, particularly asthma and asthma-related allergic disorders. Current research in his laboratory includes admixture and association analysis, transcriptome profiling and microbiome/epigenome analysis; and developing web-based bioinformatics tools specifically designed to integrate omics from public databases, such as 1000 Genomes Project, ENCODE and Epigenome Roadmap. Dr. Mersha's long-term career goals are to develop a program that will lead to an in-depth understanding of the complex interplay between genomic variations and environmental exposure risk factors in the etiology of complex diseases, including asthma.
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