Nov 17, 2020, 10:35

Mario is currently a senior at Xavier University, and is double majoring in Chemistry and Biophysics, along with minors in Math, Psychology, and Spanish. He was brought to the lab through UC’s SURF program (Summer Undergraduate Research Fellowship). After graduating from Xavier he plans to pursue an MD/PhD program. His current project focuses on the protein neural nitric oxide synthase (nNOS) and how its expression varies in brain tissue from subjects with or without schizophrenia. Nitric oxide modulates many synaptic proteins and is known to be dysregulated in schizophrenic neurons, making it an interesting protein to study. Specifically he has built an in silico protein-protein interactome for nNOS and is looking at mRNA expression levels of the targeted interacting proteins via PCR quantification. Additionally, he is working on an immunopurification of nNOS so that its interactome can be analyzed via mass spectrometry.

Name : Mario Cribari

Title : Undergraduate Student

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