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Role: Principal Investigator, Contact. Lewkowich Co-PI

Neuroimmune modulators of airway inflammation associated stress and fear responses

Using novel genetic mice models, this R21 investigates asthma-linked inflammatory mechanisms in driving posttraumatic behavior and physiology of relevance to PTSD.

02/01/2019 – 12/31/2021
Direct Costs: $255,202

I01 BX001075 (VA Merit Award)
Role: Principal Investigator

Neurovascular signaling and associated forebrain circuits in PTSD

This Merit review application focuses on how neurovascular signaling activates novel fear circuits that may contribute to PTSD susceptibility.

10/01/2020 – 09/30/2024
Direct Costs:$282,839

I01BX003858 (VA Merit Award)
Role: Co-Investigator (Herman, PI)

Neuropeptide Mechanisms and Stress Pathologies

This proposal examines the role of the prefrontal cortex pituitary adenylate cyclase-activating peptide (PACAP) in mitigating the effects of traumatic stress exposure in a preclinical model.

07/01/2017 – 12-31/2021
Direct Costs:$292,659

COM Research Innovation Pilot (RIP) Award
Role: Principal Investigator

Asthma and Fear: Cortical Transcriptomic profiling

This proposal examines the effects of aeroallergen-induced lung inflammation on brain transcriptomics, to identify relevant molecular targets and signaling pathways that may contribute to pulmonary inflammation-associated behavioral deficits.

Direct Costs: $30,000

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Pharmacology and Systems Physiology

College of Medicine
231 Albert Sabin Way
Cincinnati, OH 45267-0575

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