Meet the Fan Lab
Dr. Xiaohong Wang, Research Scientist (email)
Research Scientist, graduated from Qinghai Medical College. She has been in Dr. Fan’s laboratory since 2007 and published 34 peer-reviewed papers. Dr. Xiaohong Wang has extensive expertise in animal models, animal
surgery of cecal ligation and puncture (CLP) and cardiac ischemia/reperfusion, in vivo and ex vivo myocardial function measurement, isolation of cardiac endothelial cells, fibroblasts, myocytes, and bone
marrow-derived macrophages (BMDMs) for cell culture. Specifically, Dr. Wang has investigated the role of miRNAs and exosomes in I/R-induced cardiac injury and diabetic cardiomyopathy, which resulted in 12 first-authored or co-authored
papers. Currently, she is a lab manager and involved in multiple research projects and animal surgery.
Dr. Rubab Akbar, Post-doc Fellow (email)
Dr. Akbar received her master’s degree from National Institute of Biotechnology and Genetic Engineering (NIBGE), Pakistan, and PhD degree from Zhejiang University, China. Subsequently, Rubab joined Dr. Fan’s lab in July 2022. She is currently investigating the effects of probiotic bacteria-released extracellular vesicles (BEVs) on macrophage efferocytosis in cardiac ischemia/reperfusion injury and repair. Her project will apply expertise including Western-blotting, q-PCR, Immunofluorescence staining, genotyping, and primary cell culture etc. In addition, she will be working on advanced techniques including Flow Cytometry analysis, cardiac Ischemia/reperfusion modeling, and bioinformatic analysis of gene-network pathways.
Dr. Hui-Hui Yang, Post-doc Fellow (email)
Dr. Yang received her M.S. and Ph.D. degrees from Central South University Xiangya Medical School. Subsequently, she joined the Zhang lab at the Central South University as post-doc fellow and conducted a project about glucose metabolism in LPS-tolerant macrophages during sepsis-induced immunosuppression. During her study at the Central South University, she had published 22 scientific papers, including 6 as the first (co-first) or corresponding (co-corresponding) author, and completed 6 research projects as PI. In 2022, Dr. Yang moved to USA and joined the Fan lab working on several projects about macrophage efferocytosis/phagocytosis, vascular leakage, and organ dysfunction during sepsis and septic shock. Dr. Yang has strong background in Molecular Cellular Biology and Immunology and has extensive experience in the study of inflammation-triggered organ injury, using in vitro cell culture and in vivo animal models.
Ms. Yue-Ying Liu, PhD Student (email)
Yueying is an intelligent and motivated individual with very good work ethic and creativity. She received her bachelor’s degree in Pharmacy and Master’s degree in Pharmaceutical Science from Yanbian University, China. Yue-Ying has excellent background and experience in molecular/cellular biology and immunology. In 2022, she was recruited into the PhD program of Pharmaceutical Sciences at the University of Cincinnati College of Pharmacy. She has well-received training started with flow cytometry analysis, genotyping, qPCR, primary cell culture, etc. Currently, Yueying’s PhD thesis project in the Fan lab focuses on investigating the role of Lcn10 in macrophage efferocytosis during myocardial ischemia/reperfusion and its underlying mechanisms, using in vitro cell culture, in vivo transgenic and knockout mouse models, RNA-seq and bioinformatics analysis.
Ms. Si-Ru Li, PhD Student (email)
Siru received her Bachelor’s degree from Shandong University of Traditional Chinese Medicine, majored in Pharmacy. She got her Master’s degree from Beijing University of Chinese Medicine, majored in Materia Medica. She received her second Master’s degree from New Jersey Institute of Technology, majored in Pharmaceutical Chemistry. Now she is a Ph.D. student in the program of Pharmaceutical Science at the University of Cincinnati College of Pharmacy. Ms. Li will conduct her PhD thesis project at the Fan lab and focus on developing natural nano-drug to test the effects of probiotic bacterial EVs in clearance of pathogen during sepsis and its underlying mechanism.
Contact UsDepartment of
Pharmacology and Systems Physiology
College of Medicine
231 Albert Sabin Way
Cincinnati, OH 45267-0575