Skip to main content
Photo of  Michael Jankowski, PhD

Michael Jankowski, PhD

Research Interests

Our lab is interested in the molecular mechanisms of sensory neuron plasticity after peripheral injuries.  We have two main focuses: peripheral mechanisms of musculoskeletal pain specifically in the context of ischemia and the developmental sensitiza...

Education/Credentials
  • MS: University of Pittsburgh
  • BS: University of Pittsburgh
  • PhD: University of Pittsburgh
Contact Information
  • Cincinnati Children's Hospital Medical Center
  • 3333 Burnet Ave
  • Cincinnati, Ohio 45229
  • Office 5138037966
  • Email michael.jankowski@cchmc.org

Peer Reviewed Publications

He, Xuelian; Zhang, Liguo; Queme, Luis F; Liu, Xuezhao; Lu, Andrew; Waclaw, Ronald R; Dong, Xinran; Zhou, Wenhao; Kidd, Grahame; Yoon, Sung-Ok; Buonanno, Andres; Rubin, Joshua B; Xin, Mei; Nave, Klaus-Armin; Trapp, Bruce D; Jankowski, Michael P; Lu, Q Richard 2018. A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration. Nature medicine, 24 3, 338-351

Ross, Jessica L; Queme, Luis F; Lamb, Jordan E; Green, Kathryn J; Jankowski, Michael P 2018. Sex differences in primary muscle afferent sensitization following ischemia and reperfusion injury. Biology of sex differences, 9 1, 2

Jankowski, Michael P 2017. A new role of growth hormone and insulin-like growth factor receptor type 1 in neonatal inflammatory nociception: response to commentary. Pain reports, 2 4, e609

Jankowski, Michael P; Baumbauer, Kyle M; Wang, Ting; Albers, Kathryn M; Davis, Brian M; Koerber, H Richard 2017. Cutaneous neurturin overexpression alters mechanical, thermal, and cold responsiveness in physiologically identified primary afferents. Journal of neurophysiology, 117 3, 1258-1265

Jankowski, Michael P; Rau, Kristofer K; Koerber, H Richard 2017. Cutaneous TRPM8-expressing sensory afferents are a small population of neurons with unique firing properties. Physiological reports, 5 7,

Li, Zhuo; Peng, Yanyan; Hufnagel, Robert B; Hu, Yueh-Chiang; Zhao, Chuntao; Queme, Luis F; Khuchua, Zaza; Driver, Ashley M; Dong, Fei; Lu, Q Richard; Lindquist, Diana M; Jankowski, Michael P; Stottmann, Rolf W; Kao, Winston W Y; Huang, Taosheng 2017. Loss of SLC25A46 causes neurodegeneration by affecting mitochondrial dynamics and energy production in mice. Human molecular genetics, 26 19, 3776-3791

Liu, Xiaohua; Green, Kathryn J; Ford, Zachary K; Queme, Luis F; Lu, Peilin; Ross, Jessica L; Lee, Frank B; Shank, Aaron T; Hudgins, Renita C; Jankowski, Michael P 2017. Growth hormone regulates the sensitization of developing peripheral nociceptors during cutaneous inflammation. Pain, 158 2, 333-346

Queme, Luis F; Ross, Jessica L; Jankowski, Michael P 2017. Peripheral Mechanisms of Ischemic Myalgia. Frontiers in cellular neuroscience, 11 , 419

Ross, Jessica L; Queme, Luis F; Lamb, Jordan E; Green, Kathryn J; Ford, Zachary K; Jankowski, Michael P 2017. Interleukin 1? inhibition contributes to the antinociceptive effects of voluntary exercise on ischemia/reperfusion-induced hypersensitivity. Pain, ,

Molliver, Derek C; Rau, Kristofer K; Jankowski, Michael P; Soneji, Deepak J; Baumbauer, Kyle M; Koerber, H Richard 2016. Deletion of the murine ATP/UTP receptor P2Y2 alters mechanical and thermal response properties in polymodal cutaneous afferents. Neuroscience, 332 , 223-30

Queme, Luis F; Ross, Jessica L; Lu, Peilin; Hudgins, Renita C; Jankowski, Michael P 2016. Dual Modulation of Nociception and Cardiovascular Reflexes during Peripheral Ischemia through P2Y1 Receptor-Dependent Sensitization of Muscle Afferents. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 1, 19-30

Ross, Jessica L; Queme, Luis F; Cohen, Elysia R; Green, Kathryn J; Lu, Peilin; Shank, Aaron T; An, Suzie; Hudgins, Renita C; Jankowski, Michael P 2016. Muscle IL1? Drives Ischemic Myalgia via ASIC3-Mediated Sensory Neuron Sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 26, 6857-71

Wu, Lai Man Natalie; Wang, Jincheng; Conidi, Andrea; Zhao, Chuntao; Wang, Haibo; Ford, Zachary; Zhang, Liguo; Zweier, Christiane; Ayee, Brian G; Maurel, Patrice; Zwijsen, An; Chan, Jonah R; Jankowski, Michael P; Huylebroeck, Danny; Lu, Q Richard 2016. Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination. Nature neuroscience, 19 8, 1060-72

Pooya, Shabnam; Liu, Xiaona; Kumar, V B Sameer; Anderson, Jane; Imai, Fumiyasu; Zhang, Wujuan; Ciraolo, Georgianne; Ratner, Nancy; Setchell, Kenneth D R; Yoshida, Yutaka; Jankowski, Michael P; Dasgupta, Biplab 2015. Corrigendum: The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nature communications, 6 , 6075

Jankowski, Michael P; Ross, Jessica L; Weber, Jonathon D; Lee, Frank B; Shank, Aaron T; Hudgins, Renita C 2014. Age-dependent sensitization of cutaneous nociceptors during developmental inflammation. Molecular pain, 10 , 34

Pooya, Shabnam; Liu, Xiaona; Kumar, V B Sameer; Anderson, Jane; Imai, Fumiyasu; Zhang, Wujuan; Ciraolo, Georgianne; Ratner, Nancy; Setchell, Kenneth D R; Yoshida, Yutaka; Yutaka, Yoshida; Jankowski, Michael P; Dasgupta, Biplab 2014. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nature communications, 5 , 4993

Ross, Jessica L; Queme, Luis F; Shank, Aaron T; Hudgins, Renita C; Jankowski, Michael P 2014. Sensitization of group III and IV muscle afferents in the mouse after ischemia and reperfusion injury. The journal of pain : official journal of the American Pain Society, 15 12, 1257-70

Jankowski, Michael P; Rau, Kristofer K; Ekmann, Katrina M; Anderson, Collene E; Koerber, H Richard 2013. Comprehensive phenotyping of group III and IV muscle afferents in mouse. Journal of neurophysiology, 109 9, 2374-81

Jankowski, Michael P; Rau, Kristofer K; Soneji, Deepak J; Ekmann, Katrina M; Anderson, Collene E; Molliver, Derek C; Koerber, H Richard 2012. Purinergic receptor P2Y1 regulates polymodal C-fiber thermal thresholds and sensory neuron phenotypic switching during peripheral inflammation. Pain, 153 2, 410-9

Jankowski, Michael P; Soneji, Deepak J; Ekmann, Katrina M; Anderson, Collene E; Koerber, H Richard 2012. Dynamic changes in heat transducing channel TRPV1 expression regulate mechanically insensitive, heat sensitive C-fiber recruitment after axotomy and regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32 49, 17869-73

Li, Lishi; Rutlin, Michael; Abraira, Victoria E; Cassidy, Colleen; Kus, Laura; Gong, Shiaoching; Jankowski, Michael P; Luo, Wenqin; Heintz, Nathaniel; Koerber, H Richard; Woodbury, C Jeffery; Ginty, David D 2011. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell, 147 7, 1615-27

Molliver, Derek C; Rau, Kristofer K; McIlwrath, Sabrina L; Jankowski, Michael P; Koerber, H Richard 2011. The ADP receptor P2Y1 is necessary for normal thermal sensitivity in cutaneous polymodal nociceptors. Molecular pain, 7 , 13

Jankowski, Michael P; Rau, Kristofer K; Soneji, Deepak J; Anderson, Collene E; Koerber, H Richard 2010. Enhanced artemin/GFR?3 levels regulate mechanically insensitive, heat-sensitive C-fiber recruitment after axotomy and regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30 48, 16272-83

Koerber, H Richard; McIlwrath, Sabrina L; Lawson, Jeffrey J; Malin, Sacha A; Anderson, Collene E; Jankowski, Michael P; Davis, Brian M 2010. Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers. Molecular pain, 6 , 58

Jankowski, Michael P; Lawson, Jeffrey J; McIlwrath, Sabrina L; Rau, Kristofer K; Anderson, Collene E; Albers, Kathryn M; Koerber, H Richard 2009. Sensitization of cutaneous nociceptors after nerve transection and regeneration: possible role of target-derived neurotrophic factor signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29 6, 1636-47

Jankowski, Michael P; McIlwrath, Sabrina L; Jing, Xiaotang; Cornuet, Pamela K; Salerno, Kathleen M; Koerber, H Richard; Albers, Kathryn M 2009. Sox11 transcription factor modulates peripheral nerve regeneration in adult mice. Brain research, 1256 , 43-54

Rau, Kristofer K; McIlwrath, Sabrina L; Wang, Hong; Lawson, Jeffrey J; Jankowski, Michael P; Zylka, Mark J; Anderson, David J; Koerber, H Richard 2009. Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29 26, 8612-9

Jankowski, Michael P; Sesack, Susan R 2004. Prefrontal cortical projections to the rat dorsal raphe nucleus: ultrastructural features and associations with serotonin and gamma-aminobutyric acid neurons. The Journal of comparative neurology, 468 4, 518-29

Pinto, Aline; Jankowski, Michael; Sesack, Susan R 2003. Projections from the paraventricular nucleus of the thalamus to the rat prefrontal cortex and nucleus accumbens shell: ultrastructural characteristics and spatial relationships with dopamine afferents. The Journal of comparative neurology, 459 2, 142-55

Lu, Peilin; Hudgins, Renita C; Liu, Xiaohua; Ford, Zachary K; Hofmann, Megan C; Queme, Luis F; Jankowski, Michael Paul . Upregulation of P2Y1 in neonatal nociceptors regulates heat and mechanical sensitization during cutaneous inflammation. Molecular pain, 13 , 1744806917730255

Directory Search

Contact Us

Department of Anesthesiology

Medical Sciences Building
Room 3502
231 Albert Sabin Way
PO Box 670531
Cincinnati, OH 45267-0531

Mail Location: 0531
Phone: 513-558-2402
Fax: 513-558-0995
Email: mcclanpa@ucmail.uc.edu