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Department of

Surgery

Photo of  Michael Edwards, MD

Michael Edwards, MD

Professor

Education/Credentials
  • Bachelor's Degree: University of Georgia
  • Medical Degree: Emory University
  • General Surgery Residency: University of Louisville
  • Fellowship in General Surgical Oncology: MD Anderson Cancer Center

Board Certifications & Licenses
  • American Board of Surgery 02/23/1987
Contact Information
  • Medical Sciences Building
  • SRU Room 1469
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513-558-5333
  • Email michael.edwards@uc.edu

Peer Reviewed Publications

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Baduva, Käthe; Büchter, Lara; Kreyenkamp, Katja; Westphal, Linnea; Wilker, Barbara; Kohnen, Marcus; Schuchman, Edward H; Edwards, Michael J; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander 2019. Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 52 5, 1092-1102

Lee, Tiffany C; Kaiser, Tiffany E; Alloway, Rita; Woodle, Ervin Steve; Edwards, Michael J; Shah, Shimul A 2019. Telemedicine Based Remote Home Monitoring After Liver Transplantation: Results of a Randomized Prospective Trial. Annals of surgery, 270 3, 564-572

Popkirov, Stoyan; Nicholson, Timothy R; Bloem, Bastiaan R; Cock, Hannah R; Derry, Christopher P; Duncan, Roderick; Dworetzky, Barbara A; Edwards, Mark J; Espay, Alberto J; Hallett, Mark; Lang, Anthony E; Leach, John Paul; Lehn, Alexander; McGonigal, Aileen; Morgante, Francesca; Perez, David L; Reuber, Markus; Richardson, Mark P; Smith, Philip; Stamelou, Maria; Tijssen, Marina A J; Tinazzi, Michele; Carson, Alan J; Stone, Jon 2019. Hiding in Plain Sight: Functional Neurological Disorders in the News. The Journal of neuropsychiatry and clinical neurosciences, , appineuropsych190100

Seitz, Aaron P; Schumacher, Fabian; Baker, Jennifer; Soddemann, Matthias; Wilker, Barbara; Caldwell, Charles C; Gobble, Ryan M; Kamler, Markus; Becker, Katrin Anne; Beck, Sascha; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich 2019. Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia. Journal of molecular medicine (Berlin, Germany), 97 8, 1195-1211

Becker, Katrin Anne; Fahsel, Björn; Kemper, Hannes; Mayeres, Joelina; Li, Cao; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Sehl, Carolin; Kohnen, Marcus; Edwards, Michael J; Grassmé, Heike; Caldwell, Charles C; Seitz, Aaron; Fraunholz, Martin; Gulbins, Erich 2018. Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide. Infection and immunity, 86 1,

Becker, Katrin Anne; Riethmüller, Joachim; Seitz, Aaron P; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C; Edwards, Michael J; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich 2018. Sphingolipids as targets for inhalation treatment of cystic fibrosis. Advanced drug delivery reviews, 133 , 66-75

Cortez, Alexander R; Dhar, Vikrom K; Sussman, Jeffrey J; Pritts, Timothy A; Edwards, Michael J; Quillin, R Cutler 2018. Not all operative experiences are created equal: a 19-year analysis of a single center's case logs. The Journal of surgical research, 229 , 127-133

Cortez, Alexander R; Katsaros, Gianna D; Dhar, Vikrom K; Drake, F Thurston; Pritts, Timothy A; Sussman, Jeffrey J; Edwards, Michael J; Quillin, R Cutler 2018. Narrowing of the surgical resident operative experience: A 27-year analysis of national ACGME case logs. Surgery, 164 3, 577-582

Gulbins, Anne; Schumacher, Fabian; Becker, Katrin Anne; Wilker, Barbara; Soddemann, Matthias; Boldrin, Francesco; Müller, Christian P; Edwards, Michael J; Goodman, Michael; Caldwell, Charles C; Kleuser, Burkhard; Kornhuber, Johannes; Szabo, Ildiko; Gulbins, Erich 2018. Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide. Molecular psychiatry, 23 12, 2324-2346

Jung, Andrew D; Dhar, Vikrom K; Hoehn, Richard S; Atkinson, Sarah J; Johnson, Bobby L; Rice, Teresa; Snyder, Jonathan R; Rafferty, Janice F; Edwards, Michael J; Paquette, Ian M 2018. Enhanced Recovery after Colorectal Surgery: Can We Afford Not to Use It? Journal of the American College of Surgeons, 226 4, 586-593

Keitsch, Simone; Riethmüller, Joachim; Soddemann, Matthias; Sehl, Carolin; Wilker, Barbara; Edwards, Michael J; Caldwell, Charles C; Fraunholz, Martin; Gulbins, Erich; Becker, Katrin Anne 2018. Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of ?-toxin. Biological chemistry, 399 10, 1203-1213

Kim, Young; Cortez, Alexander R; Wima, Koffi; Dhar, Vikrom K; Athota, Krishna P; Schrager, Jason J; Pritts, Timothy A; Edwards, Michael J; Shah, Shimul A 2018. Impact of Preoperative Opioid Use After Emergency General Surgery. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 22 6, 1098-1103

Dhar, Vikrom K; Levinsky, Nick C; Xia, Brent T; Abbott, Daniel E; Wilson, Gregory C; Sussman, Jeffrey J; Smith, Milton T; Poreddy, Sampath; Choe, Kyuran; Hanseman, Dennis J; Edwards, Michael J; Ahmad, Syed A 2016. The natural history of chronic pancreatitis after operative intervention: The need for revisional operation. Surgery, ,

Ertel, Audrey E; Wima, Koffi; Chang, Alex L; Hoehn, Richard S; Hohmann, Samual F; Edwards, Michael J; Abbott, Daniel E; Shah, Shimul A 2016. Risk of Reoperation Within 90 Days of Liver Transplantation: A Necessary Evil? Journal of the American College of Surgeons, 222 4, 419-28

Hoehn, Richard S; Jernigan, Peter L; Chang, Alex L; Edwards, Michael J; Caldwell, Charles C; Gulbins, Erich; Pritts, Timothy A 2016. Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 1, 331-40

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A 2016. Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation. Annals of surgery, ,

Hoehn, Richard; Monse, Marlene; Pohl, Ella; Wranik, Sina; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Kornhuber, Johannes; Kohnen, Marcus; Edwards, Michael J; Grassmé, Heike; Gulbins, Erich 2016. Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System. Neuro-Signals, 24 1, 48-58

McMasters, Kelly M; Egger, Michael E; Edwards, Michael J; Ross, Merrick I; Reintgen, Douglas S; Noyes, R Dirk; Martin, Robert C G; Goydos, James S; Beitsch, Peter D; Urist, Marshall M; Ariyan, Stephan; Sussman, Jeffrey J; Davidson, B Scott; Gershenwald, Jeffrey E; Hagendoorn, Lee J; Stromberg, Arnold J; Scoggins, Charles R 2016. Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 34 10, 1079-86

Nojima, Hiroyuki; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B 2016. Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. Journal of hepatology, 64 1, 60-8

Quillin, Ralph C; Cortez, Alexander R; Pritts, Timothy A; Hanseman, Dennis J; Edwards, Michael J; Davis, Bradley R 2016. Operative Variability Among Residents Has Increased Since Implementation of the 80-Hour Workweek. Journal of the American College of Surgeons, 222 6, 1201-10

Quillin, Ralph C; Cortez, Alexander R; Pritts, Timothy A; Hanseman, Dennis J; Edwards, Michael J; Davis, Bradley R 2016. Surgical resident learning styles have changed with work hours. The Journal of surgical research, 200 1, 39-45

Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C 2016. Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection. Journal of leukocyte biology, ,

Carpinteiro, Alexander; Becker, Katrin Anne; Japtok, Lukasz; Hessler, Gabriele; Keitsch, Simone; Požgajovà, Miroslava; Schmid, Kurt W; Adams, Constantin; Müller, Stefan; Kleuser, Burkhard; Edwards, Michael J; Grassmé, Heike; Helfrich, Iris; Gulbins, Erich 2015. Regulation of hematogenous tumor metastasis by acid sphingomyelinase. EMBO molecular medicine, 7 6, 714-34

Gulbins, Erich; Walter, Silke; Becker, Katrin Anne; Halmer, Ramona; Liu, Yang; Reichel, Martin; Edwards, Michael J; Müller, Christian P; Fassbender, Klaus; Kornhuber, Johannes 2015. A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression. Journal of neurochemistry, 134 2, 183-92

Henry, Brian D; Neill, Daniel R; Becker, Katrin Anne; Gore, Suzanna; Bricio-Moreno, Laura; Ziobro, Regan; Edwards, Michael J; Mühlemann, Kathrin; Steinmann, Jörg; Kleuser, Burkhard; Japtok, Lukasz; Luginbühl, Miriam; Wolfmeier, Heidi; Scherag, André; Gulbins, Erich; Kadioglu, Aras; Draeger, Annette; Babiychuk, Eduard B 2015. Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. Nature biotechnology, 33 1, 81-8

Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B 2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice. Hepatology research : the official journal of the Japan Society of Hepatology, 45 3, 305-14

Wilson, Gregory C; Freeman, Christopher M; Kuethe, Joshua W; Quillin, Ralph C; Nojima, Hiroyuki; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B 2015. CXC chemokine receptor-4 signaling limits hepatocyte proliferation after hepatic ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 308 8, G702-9

Wilson, Gregory C; Kuboki, Satoshi; Freeman, Christopher M; Nojima, Hiroyuki; Schuster, Rebecca M; Edwards, Michael J; Lentsch, Alex B 2015. CXC chemokines function as a rheostat for hepatocyte proliferation and liver regeneration. PloS one, 10 3, e0120092

Wilson, Gregory C; Sutton, Jeffrey M; Smith, Milton T; Schmulewitz, Nathan; Salehi, Marzieh; Choe, Kyuran A; Levinsky, Nick C; Brunner, John E; Abbott, Daniel E; Sussman, Jeffrey J; Edwards, Michael J; Ahmad, Syed A 2015. Completion pancreatectomy and islet cell autotransplantation as salvage therapy for patients failing previous operative interventions for chronic pancreatitis. Surgery, 158 4, 872-8; discussion 87

Abbott, Daniel E; Sutton, Jeffrey M; Edwards, Michael J 2014. Making the case for cost-effectiveness research. Journal of surgical oncology, 109 6, 509-15

Freeman, Christopher M; Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Johnson, Bobby L; Sutton, Jeffrey M; Schuster, Rebecca M; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B 2014. Characterization of microparticles after hepatic ischemia-reperfusion injury. PloS one, 9 5, e97945

Pewzner-Jung, Yael; Tavakoli Tabazavareh, Shaghayegh; Grassmé, Heike; Becker, Katrin Anne; Japtok, Lukasz; Steinmann, Jörg; Joseph, Tammar; Lang, Stephan; Tuemmler, Burkhard; Schuchman, Edward H; Lentsch, Alex B; Kleuser, Burkhard; Edwards, Michael J; Futerman, Anthony H; Gulbins, Erich 2014. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. EMBO molecular medicine, 6 9, 1205-14

Sutton, Jeffrey M; Kooby, David A; Wilson, Gregory C; Squires, M Hart; Hanseman, Dennis J; Maithel, Shishir K; Bentrem, David J; Weber, Sharon M; Cho, Clifford S; Winslow, Emily R; Scoggins, Charles R; Martin, Robert C G; Kim, Hong Jin; Baker, Justin J; Merchant, Nipun B; Parikh, Alexander A; Abbott, Daniel E; Edwards, Michael J; Ahmad, Syed A 2014. Perioperative blood transfusion is associated with decreased survival in patients undergoing pancreaticoduodenectomy for pancreatic adenocarcinoma: a multi-institutional study. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 18 9, 1575-87

Sutton, Jeffrey M; Wilson, Gregory C; Paquette, Ian M; Wima, Koffi; Hanseman, Dennis J; Quillin, R Cutler; Sussman, Jeffrey J; Edwards, Michael J; Ahmad, Syed A; Shah, Shimul A; Abbott, Daniel E 2014. Cost effectiveness after a pancreaticoduodenectomy: bolstering the volume argument. HPB : the official journal of the International Hepato Pancreato Biliary Association, 16 12, 1056-61

Wilson, Gregory C; Sutton, Jeffrey M; Abbott, Daniel E; Smith, Milton T; Lowy, Andrew M; Matthews, Jeffrey B; Rilo, Horacio L R; Schmulewitz, Nathan; Salehi, Marzieh; Choe, Kyuran; Brunner, John; Hanseman, Dennis J; Sussman, Jeffrey J; Edwards, Michael J; Ahmad, Syed A 2014. Long-term outcomes after total pancreatectomy and islet cell autotransplantation: is it a durable operation? Annals of surgery, 260 4, 659-65; discussion 6

Alexander, J Wesley; Van Sweringen, Heather; Vanoss, Katherine; Hooker, Edmond A; Edwards, Michael J 2013. Surveillance of bacterial colonization in operating rooms. Surgical infections, 14 4, 345-51

Quillin, Ralph C; Burns, Justin M; Pineda, Jaime A; Hanseman, Dennis; Rudich, Steven M; Edwards, Michael J; Tevar, Amit D 2013. Laparoscopic cholecystectomy in the cirrhotic patient: predictors of outcome. Surgery, 153 5, 634-40

Quillin, Ralph C; Pritts, Timothy A; Tevar, Amit D; Hanseman, Dennis J; Edwards, Michael J; Davis, Bradley R 2013. Students' expectations on the surgery clerkship exceed those of residents and faculty. The Journal of surgical research, 184 1, 495-500

Van Sweringen, Heather L; Sakai, Nozomu; Quillin, Ralph C; Bailey, Jeff; Schuster, Rebecca; Blanchard, John; Goetzman, Holly; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B 2013. Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 57 1, 331-8

Wilson, Gregory C; Quillin, Ralph C; Hanseman, Dennis J; Lewis, Jaime D; Edwards, Michael J; Shaughnessy, Elizabeth A 2013. Incidence and predictors of neuropathic pain following breast surgery. Annals of surgical oncology, 20 10, 3330-4

Ahmad, Syed A; Edwards, Michael J; Sutton, Jeffrey M; Grewal, Sanjeet S; Hanseman, Dennis J; Maithel, Shishir K; Patel, Sameer H; Bentram, David J; Weber, Sharon M; Cho, Clifford S; Winslow, Emily R; Scoggins, Charles R; Martin, Robert C; Kim, Hong Jin; Baker, Justin J; Merchant, Nipun B; Parikh, Alexander A; Kooby, David A 2012. Factors influencing readmission after pancreaticoduodenectomy: a multi-institutional study of 1302 patients. Annals of surgery, 256 3, 529-37

Belizaire, Ritha M; Prakash, Priya S; Richter, Jillian R; Robinson, Bryce R; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B; Pritts, Timothy A 2012. Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation. Journal of the American College of Surgeons, 214 4, 648-55; discussion 6

Quillin, Ralph C; Pritts, Timothy A; Davis, Bradley R; Hanseman, Dennis; Collins, Jocelyn M; Athota, Krishna P; Edwards, Michael J; Tevar, Amit D 2012. Surgeons underestimate their influence on medical students entering surgery. The Journal of surgical research, 177 2, 201-6

Sakai, Nozomu; Van Sweringen, Heather L; Belizaire, Ritha M; Quillin, Ralph Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells. Journal of gastroenterology and hepatology, 27 10, 1609-16

Sakai, Nozomu; Van Sweringen, Heather L; Quillin, R Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 56 4, 1468-78

Sakai, Nozomu; Van Sweringen, Heather L; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2012. Receptor activator of nuclear factor-?B ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice. Hepatology (Baltimore, Md.), 55 3, 888-97

Van Sweringen, Heather L; Hanseman, Dennis J; Ahmad, Syed A; Edwards, Michael J; Sussman, Jeffrey J 2012. Predictors of survival in patients with high-grade peritoneal metastases undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Surgery, 152 4, 617-24; discussion 6

Alexander, J Wesley; Solomkin, Joseph S; Edwards, Michael J 2011. Updated recommendations for control of surgical site infections. Annals of surgery, 253 6, 1082-93

Clarke, Callisia; Kuboki, Satoshi; Sakai, Nozomu; Kasten, Kevin R; Tevar, Amit D; Schuster, Rebecca; Blanchard, John; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B 2011. CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury. Hepatology (Baltimore, Md.), 53 1, 261-71

Clarke, Callisia; Sakai, Nozomu; Tevar, Amit D; Schuster, Rebecca; Edwards, Michael J; Lentsch, Alex B 2011. STAT3 does not regulate acute liver injury after ischemia/reperfusion. The Journal of surgical research, 171 2, 814-8

Sakai, N; Kuboki, S; Van Sweringen, H L; Tevar, A D; Schuster, R; Blanchard, J; Edwards, M J; Lentsch, A B 2011. CXCR1 deficiency does not alter liver regeneration after partial hepatectomy in mice. Transplantation proceedings, 43 5, 1967-70

Tevar, Amit D; Clarke, Callisia N; Schuster, Rebecca; Wang, Jiang; Edwards, Michael J; Lentsch, Alex B 2011. The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis. The Journal of surgical research, 169 1, e7-14

Van Sweringen, Heather L; Sakai, Nozomu; Tevar, Amit D; Burns, Justin M; Edwards, Michael J; Lentsch, Alex B 2011. CXC chemokine signaling in the liver: impact on repair and regeneration. Hepatology (Baltimore, Md.), 54 4, 1445-53

Lewis, Jaime D; Chagpar, Anees B; Shaughnessy, Elizabeth A; Nurko, Jacob; McMasters, Kelly; Edwards, Michael J 2010. Excellent outcomes with adjuvant toremifene or tamoxifen in early stage breast cancer. Cancer, 116 10, 2307-15

Sakai, Nozomu; Clarke, Callisia N; Schuster, Rebecca; Blanchard, John; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B 2010. Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes. World journal of gastroenterology, 16 30, 3816-26

Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B 2009. Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. American journal of physiology. Gastrointestinal and liver physiology, 296 2, G266-74

Huber, Nadine; Sakai, Nozomu; Eismann, Thorsten; Shin, Thomas; Kuboki, Satoshi; Blanchard, John; Schuster, Rebecca; Edwards, Michael J; Wong, Hector R; Lentsch, Alex B 2009. Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion. Hepatology (Baltimore, Md.), 49 5, 1718-28

Kuboki, Satoshi; Sakai, Nozomu; Clarke, Callisia; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B 2009. The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury. Journal of hepatology, 51 2, 296-306

Kuboki, Satoshi; Sakai, Nozomu; Tschöp, Johannes; Edwards, Michael J; Lentsch, Alex B; Caldwell, Charles C 2009. Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury. American journal of physiology. Gastrointestinal and liver physiology, 296 5, G1054-9

Lewis, Jaime D; Pritts, Timothy A; Lentsch, Alex B; Edwards, Michael J 2009. The University of Cincinnati College of Medicine Department of Surgery. The American surgeon, 75 2, 113-9

Kuboki, Satoshi; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B 2008. Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice. Hepatology (Baltimore, Md.), 48 4, 1213-23

Chagpar,A.B.; McMasters,K.M.; Saul,J.; Nurko,J.; Martin,R.C.,2nd; Scoggins,C.R.; Edwards,M.J. 2007. Body mass index influences palpability but not stage of breast cancer at diagnosis The American Surgeon, 73 6, 555

Chagpar,R.B.; Ross,M.I.; Reintgen,D.S.; Edwards,M.J.; Scoggins,C.R.; Martin,R.C.,2nd; Noyes,R.D.; Goydos,J.S.; Beitsch,P.D.; Urist,M.M.; Ariyan,S.; Davidson,B.S.; Sussman,J.J.; McMasters,K.M. 2007. Factors associated with improved survival among young adult melanoma patients despite a greater incidence of sentinel lymph node metastasis The Journal of surgical research, 143 1, 164

Ali,A.T.; Clagett,G.P.; Edwards,M.J. 2006. Complex venous and arterial reconstruction with deep vein after pelvic exenterative surgery: a case report The American Surgeon, 72 1, 22

Chagpar,A.B.; McMasters,K.M.; Martin,R.C.; Thoene,C.; Nurko,J.Y.; Edwards,M.J.; North American Fareston Tamoxifen Adjuvant Trial 2006. Determinants of early distant metastatic disease in elderly patients with breast cancer American Journal of Surgery, 192 3, 317

Scoggins,C.R.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Goydos,J.S.; Beitsch,P.D.; Urist,M.M.; Ariyan,S.; Davidson,B.S.; Sussman,J.J.; Edwards,M.J.; Martin,R.C.; Lewis,A.M.; Stromberg,A.J.; Conrad,A.J.; Hagendoorn,L.; Albrecht,J.; McMasters,K.M. 2006. Prospective multi-institutional study of reverse transcriptase polymerase chain reaction for molecular staging of melanoma Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 18, 2849

Scoggins,C.R.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Goydos,J.S.; Beitsch,P.D.; Urist,M.M.; Ariyan,S.; Sussman,J.J.; Edwards,M.J.; Chagpar,A.B.; Martin,R.C.; Stromberg,A.J.; Hagendoorn,L.; McMasters,K.M.; Sunbelt Melanoma Trial 2006. Gender-related differences in outcome for melanoma patients Annals of Surgery, 243 5, 693

Buschemeyer,W.C.,3rd; Cunningham,D.K.; Edwards,M.J. 2005. Surgical training and implementation of emerging surgical technologies American Journal of Surgery, 190 2, 166

Conn,C.A.; McMasters,K.M.; Edwards,M.J.; Martin,R.C. 2005. Acceptance of sentinel lymph node biopsy of the breast by all general surgeons in kentucky The breast journal, 11 4, 231

Edwards MJ 2005. Substantive fulfillment of the Polk Prophecy Am J Surg, 190 , 157

Martin,R.C.,2nd; Chagpar,A.; Scoggins,C.R.; Edwards,M.J.; Hagendoorn,L.; Stromberg,A.J.; McMasters,K.M.; University of Louisville Breast Cancer Sentinel Lymph Node Study 2005. Clinicopathologic factors associated with false-negative sentinel lymph-node biopsy in breast cancer Annals of Surgery, 241 6, 1005

Martin,R.C.,2nd; Scoggins,C.R.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Edwards,M.J.; McMasters,K.M. 2005. Is incisional biopsy of melanoma harmful? American Journal of Surgery, 190 6, 913

Nurko,J.; Edwards,M.J. 2005. Image-guided breast surgery American Journal of Surgery, 190 2, 221

Nurko,J.; Mabry,C.D.; Whitworth,P.; Jarowenko,D.; Oetting,L.; Potruch,T.; Han,L.; Edwards,M.J. 2005. Interim results from the fibroadenoma cryoablation treatment registry American Journal of Surgery, 190 4, 647

Nurko,J.; Mancino,A.T.; Whitacre,E.; Edwards,M.J. 2005. Surgical benefits conveyed by biopsy site marking system using ultrasound localization American Journal of Surgery, 190 4, 618

Chagpar,A.; Martin,R.C.,3rd; Chao,C.; Wong,S.L.; Edwards,M.J.; Tuttle,T.; McMasters,K.M. 2004. Validation of subareolar and periareolar injection techniques for breast sentinel lymph node biopsy Archives of surgery (Chicago, Ill.: 1960), 139 6, 614

Chao,C.; Martin,R.C.,2nd; Ross,M.I.; Reintgen,D.S.; Edwards,M.J.; Noyes,R.D.; Hagendoorn,L.J.; Stromberg,A.J.; McMasters,K.M. 2004. Correlation between prognostic factors and increasing age in melanoma Annals of surgical oncology, 11 3, 259

Chao,C.; Wong,S.L.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Ley,P.; McGlothin,T.; Laidley,A.; Simpson,D.; Edwards,M.J.; McMasters,K.M.; For the University of Louisville Breast Cancer Study Group 2004. Sentinel lymph node biopsy for breast cancer: improvement in results over time The breast journal, 10 4, 337

Edwards,M.J.; Broadwater,R.; Tafra,L.; Jarowenki,D.; Mabry,C.; Beitsch,P.; Whitworth,P.; Martin,R.C.; Oetting,L. 2004. Progressive adoption of cryoablative therapy for breast fibroadenoma in community practice American Journal of Surgery, 188 3, 221

Martin,R.C.; Edwards,M.J.; McMasters,K.M. 2004. Morbidity of adjuvant hepatic arterial infusion pump chemotherapy in the management of colorectal cancer metastatic to the liver American Journal of Surgery, 188 6, 714

Sloan,D.A.; Plymale,M.A.; Donnelly,M.B.; Schwartz,R.W.; Edwards,M.J.; Bland,K.I. 2004. Enhancing the clinical skills of surgical residents through structured cancer education Annals of Surgery, 239 4, 561

Beitsch,P.D.; Lerner,A.G.; Laidley,A.L.; Tafra,L.; Edwards,M.J. 2003. Who are we and what do we think? American Journal of Surgery, 186 4, 321

Chao,C.; Edwards,M.J.; Abell,T.; Wong,S.L.; Simpson,D.; McMasters,K.M. 2003. Palpable breast carcinomas: a hypothesis for clinically relevant lymphatic drainage in sentinel lymph node biopsy The breast journal, 9 1, 26

Chao,C.; Edwards,M.J.; Wolfson,S.; Sewell,C.; Edwards,D.; McMasters,K.M. 2003. Paget's disease of the male breast: an unusual case of dermal invasion The breast journal, 9 3, 254

Chao,C.; Wong,S.L.; Edwards,M.J.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Stadelmann,W.K.; Lentsch,E.; McMasters,K.M.; Sunbelt Melanoma Trial Group 2003. Sentinel lymph node biopsy for head and neck melanomas Annals of surgical oncology, 10 1, 21

Edwards,M. 2003. The nouns that define us American Journal of Surgery, 186 4, 317

Edwards,M.J. 2003. Office-based and intraoperative ultrasound enhance surgeon's care of breast disease patients Annals of surgical oncology, 10 2, 201

Gamel,J.W.; Bonadonna,G.; Valagussa,P.; Edwards,M.J. 2003. Refined measurement of outcome for adjuvant breast carcinoma therapy Cancer, 97 5, 1139

Wrightson,W.R.; Wong,S.L.; Edwards,M.J.; Chao,C.; Reintgen,D.S.; Ross,M.I.; Noyes,R.D.; Viar,V.; Cerrito,P.B.; McMasters,K.M.; Sunbelt Melanoma Trial Study Group 2003. Complications associated with sentinel lymph node biopsy for melanoma Annals of surgical oncology, 10 6, 676

Chao,C.; DeWeese,R.C.; Juhl,G.L.; McMasters,K.M.; Edwards,M.J. 2002. State-of-the-art breast care: multidisciplinary breast conference The Journal of the Kentucky Medical Association, 100 4, 138

Chao,C.; McMasters,K.M.; Edwards,M.J. 2002. Advances in the treatment of soft-tissue sarcomas The Journal of the Kentucky Medical Association, 100 1, 10

Chao,C.; Wong,S.L.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Cerrito,P.B.; Edwards,M.J.; McMasters,K.M.; Sunbelt Melanoma Trial Group 2002. Patterns of early recurrence after sentinel lymph node biopsy for melanoma American Journal of Surgery, 184 6, 520

Gamel,J.W.; George,S.L.; Edwards,M.J.; Seigler,H.F. 2002. The long-term clinical course of patients with cutaneous melanoma Cancer, 95 6, 1286

Kato,A.; Edwards,M.J.; Lentsch,A.B. 2002. Gene deletion of nf-kappa b p50 does not alter the hepatic inflammatory response to ischemia/reperfusion Journal of hepatology, 37 1, 48

Kato,A.; Graul-Layman,A.; Edwards,M.J.; Lentsch,A.B. 2002. Promotion of hepatic ischemia/reperfusion injury by il-12 is independent of stat4 Transplantation, 73 7, 1142

Kato,A.; Singh,S.; McLeish,K.R.; Edwards,M.J.; Lentsch,A.B. 2002. Mechanisms of hypothermic protection against ischemic liver injury in mice American journal of physiology.Gastrointestinal and liver physiology, 282 4, G608

Martin,R.C.,2nd; Vitale,G.C.; Reed,D.N.; Larson,G.M.; Edwards,M.J.; McMasters,K.M. 2002. Cost comparison of endoscopic stenting vs surgical treatment for unresectable cholangiocarcinoma Surgical endoscopy, 16 4, 667

McMasters,K.M.; Chao,C.; Wong,S.L.; Martin,R.C.,3rd; Edwards,M.J. 2002. Sentinel lymph node biopsy in patients with ductal carcinoma in situ: a proposal Cancer, 95 1, 15

McMasters,K.M.; Chao,C.; Wong,S.L.; Wrightson,W.R.; Ross,M.I.; Reintgen,D.S.; Noyes,R.D.; Cerrito,P.B.; Edwards,M.J.; Sunbelt Melanoma Trial Group 2002. Interval sentinel lymph nodes in melanoma Archives of surgery (Chicago, Ill.: 1960), 137 5, 543

McMasters,K.M.; Wong,S.L.; Edwards,M.J.; Chao,C.; Ross,M.I.; Noyes,R.D.; Viar,V.; Cerrito,P.B.; Reintgen,D.S. 2002. Frequency of nonsentinel lymph node metastasis in melanoma Annals of surgical oncology, 9 2, 137

Tien,H.Y.; McMasters,K.M.; Edwards,M.J.; Chao,C. 2002. Sentinel lymph node metastasis in anal melanoma: a case report International journal of gastrointestinal cancer, 32 1, 53

Wong,S.L.; Abell,T.D.; Chao,C.; Edwards,M.J.; McMasters,K.M. 2002. Optimal use of sentinel lymph node biopsy versus axillary lymph node dissection in patients with breast carcinoma: a decision analysis Cancer, 95 3, 478

Wong,S.L.; Chao,C.; Edwards,M.J.; Carlson,D.J.; Laidley,A.; Noyes,R.D.; McGlothin,T.; Ley,P.B.; Tuttle,T.; Schadt,M.; Pennington,R.; Legenza,M.; Morgan,J.; McMasters,K.M.; University of Louisville Breast Cancer Study Group 2002. Frequency of sentinel lymph node metastases in patients with favorable breast cancer histologic subtypes American Journal of Surgery, 184 6, 492

Wong,S.L.; Edwards,M.J.; Chao,C.; Simpson,D.; McMasters,K.M. 2002. The effect of lymphatic tumor burden on sentinel lymph node biopsy results The breast journal, 8 4, 192

Wong,S.L.; Edwards,M.J.; Chao,C.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Laidley,A.L.; McGlothin,T.Q.; Ley,P.B.; Brown,C.M.; Glaser,R.L.; Pennington,R.E.; Turk,P.S.; Simpson,D.; McMasters,K.M.; University of Louisville Breast Cancer Study Group 2002. The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy Annals of surgical oncology, 9 3, 272

Chao,C.; Wong,S.L.; Ackermann,D.; Simpson,D.; Carter,M.B.; Brown,C.M.; Edwards,M.J.; McMasters,K.M. 2001. Utility of intraoperative frozen section analysis of sentinel lymph nodes in breast cancer American Journal of Surgery, 182 6, 609

Chao,C.; Wong,S.L.; Woo,C.; Edwards,M.J.; Tuttle,T.; Noyes,R.D.; Carlson,D.J.; Turk,P.; Simpson,D.; McMasters,K.M. 2001. Reliable lymphatic drainage to axillary sentinel lymph nodes regardless of tumor location within the breast American Journal of Surgery, 182 4, 307

Dowlat,K.; Robinson,D.; Schwartzberg,B.; Singletary,E.; Pass,H.; Gittleman,M.; Edwards,M. 2001. 2001 image-guided percutaneous breast cancer ablation meeting at the american society of breast surgeons American Journal of Surgery, 182 4, 429

Edwards,M.J.; Mahoney,M.C. 2001. Image-guided needle breast biopsy Breast disease, 12 , 13

Lentsch,A.B.; Kato,A.; Davis,B.; Wang,W.; Chao,C.; Edwards,M.J. 2001. Stat4 and stat6 regulate systemic inflammation and protect against lethal endotoxemia The Journal of clinical investigation, 108 10, 1475

Martin,R.C.,2nd; Edwards,M.J.; McMasters,K.M. 2001. Histoplasmosis as an isolated liver lesion: review and surgical therapy The American Surgeon, 67 5, 430

McMasters,K.M.; Reintgen,D.S.; Ross,M.I.; Gershenwald,J.E.; Edwards,M.J.; Sober,A.; Fenske,N.; Glass,F.; Balch,C.M.; Coit,D.G. 2001. Sentinel lymph node biopsy for melanoma: controversy despite widespread agreement Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 19 11, 2851

McMasters,K.M.; Reintgen,D.S.; Ross,M.I.; Wong,S.L.; Gershenwald,J.E.; Krag,D.N.; Noyes,R.D.; Viar,V.; Cerrito,P.B.; Edwards,M.J. 2001. Sentinel lymph node biopsy for melanoma: how many radioactive nodes should be removed? Annals of surgical oncology, 8 3, 192

McMasters,K.M.; Wong,S.L.; Chao,C.; Woo,C.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Laidley,A.L.; McGlothin,T.Q.; Ley,P.B.; Brown,C.M.; Glaser,R.L.; Pennington,R.E.; Turk,P.S.; Simpson,D.; Edwards,M.J.; University of Louisville Breast Cancer Study Group 2001. Defining the optimal surgeon experience for breast cancer sentinel lymph node biopsy: a model for implementation of new surgical techniques Annals of Surgery, 234 3, 292

McMasters,K.M.; Wong,S.L.; Edwards,M.J.; Ross,M.I.; Chao,C.; Noyes,R.D.; Viar,V.; Cerrito,P.B.; Reintgen,D.S. 2001. Factors that predict the presence of sentinel lymph node metastasis in patients with melanoma Surgery, 130 2, 151

McMasters,K.M.; Wong,S.L.; Martin,R.C.,2nd; Chao,C.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Laidley,A.L.; McGlothin,T.Q.; Ley,P.B.; Brown,C.M.; Glaser,R.L.; Pennington,R.E.; Turk,P.S.; Simpson,D.; Cerrito,P.B.; Edwards,M.J.; University of Louisville Breast Cancer Study Group 2001. Dermal injection of radioactive colloid is superior to peritumoral injection for breast cancer sentinel lymph node biopsy: results of a multiinstitutional study Annals of Surgery, 233 5, 676

Wong,S.L.; Chao,C.; Edwards,M.J.; Simpson,D.; McMasters,K.M.; University of Louisville Breast Cancer Study Group 2001. The use of cytokeratin staining in sentinel lymph node biopsy for breast cancer American Journal of Surgery, 182 4, 330

Wong,S.L.; Chao,C.; Edwards,M.J.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Laidley,A.L.; McGlothin,T.Q.; Ley,P.B.; Brown,C.M.; Glaser,R.L.; Pennington,R.E.; Turk,P.S.; Simpson,D.; McMasters,K.M. 2001. Accuracy of sentinel lymph node biopsy for patients with t2 and t3 breast cancers The American Surgeon, 67 6, 522

Wong,S.L.; Edwards,M.J.; Chao,C.; Simpson,D.; McMasters,K.M. 2001. Radiofrequency ablation for unresectable hepatic tumors American Journal of Surgery, 182 6, 552

Wong,S.L.; Edwards,M.J.; Chao,C.; Tuttle,T.M.; Noyes,R.D.; Carlson,D.J.; Cerrito,P.B.; McMasters,K.M. 2001. Sentinel lymph node biopsy for breast cancer: impact of the number of sentinel nodes removed on the false-negative rate Journal of the American College of Surgeons, 192 6, 684

Wong,S.L.; Edwards,M.J.; Chao,C.; Tuttle,T.M.; Noyes,R.D.; Woo,C.; Cerrito,P.B.; McMasters,K.M.; University of Louisville Breast Cancer Sentinel Lymph Node Study Group 2001. Predicting the status of the nonsentinel axillary nodes: a multicenter study Archives of surgery (Chicago, Ill.: 1960), 136 5, 563

Wrightson,W.R.; Wong,S.L.; Edwards,M.J.; Chao,C.; Conrad,A.J.; Albrecht,J.; Viar,V.; McMasters,K.M. 2001. Reverse transcriptase-polymerase chain reaction (rt-pcr) analysis of nonsentinel nodes following completion lymphadenectomy for melanoma The Journal of surgical research, 98 1, 47

Bergamini,T.M.; Edwards,M.J. 2000. Vascular problems of the pelvis Journal of surgical oncology, 73 4, 263

Edwards,M.J.; Whitworth,P.; Tafra,L.; McMasters,K.M. 2000. The details of successful sentinel lymph node staging for breast cancer American Journal of Surgery, 180 4, 257

Friedell,G.H.; Ross,F.E.; Tucker,T.C.; Cook,C.C.,3rd; Doering,D.L.; Hilgers,R.; Milburn,C.S.; Pursell,S.H.; Spires,S.E.; Hinton,M.; Sorrell,C.; Edwards,M.J. 2000. Cervical cancer in kentucky The Journal of the Kentucky Medical Association, 98 9, 398

Kato A, Lentsch AB, Edwards MJ 2000. Activation of Stat6 regulates hepatic ischemia/reperfusion injury Surgical Forum, 191 4, S24

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. 2000. Reduced hepatic ischemia/reperfusion injury by il-4: potential anti-inflammatory role of stat6 Inflammation research : official journal of the European Histamine Research Society ...[et al.], 49 6, 275

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. 2000. Regulation of liver inflammatory injury by signal transducer and activator of transcription-6 The American journal of pathology, 157 1, 297

Lentsch,A.B.; Kato,A.; Yoshidome,H.; McMasters,K.M.; Edwards,M.J. 2000. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury Hepatology (Baltimore, Md.), 32 2, 169

Martin,R.C.,2nd; Edwards,M.J.; Cawte,T.G.; Sewell,C.L.; McMasters,K.M. 2000. Basosquamous carcinoma: analysis of prognostic factors influencing recurrence Cancer, 88 6, 1365

Martin,R.C.,2nd; Edwards,M.J.; Wong,S.L.; Tuttle,T.M.; Carlson,D.J.; Brown,C.M.; Noyes,R.D.; Glaser,R.L.; Vennekotter,D.J.; Turk,P.S.; Tate,P.S.; Sardi,A.; Cerrito,P.B.; McMasters,K.M. 2000. Practical guidelines for optimal gamma probe detection of sentinel lymph nodes in breast cancer: results of a multi-institutional study. for the university of louisville breast cancer study group Surgery, 128 2, 139

Martin,R.C.,2nd; Osborne,D.L.; Edwards,M.J.; Wrightson,W.; McMasters,K.M. 2000. Giant cell tumor of tendon sheath, tenosynovial giant cell tumor, and pigmented villonodular synovitis: defining the presentation, surgical therapy and recurrence Oncology reports, 7 2, 413

McMasters,K.M.; Tuttle,T.M.; Carlson,D.J.; Brown,C.M.; Noyes,R.D.; Glaser,R.L.; Vennekotter,D.J.; Turk,P.S.; Tate,P.S.; Sardi,A.; Cerrito,P.B.; Edwards,M.J. 2000. Sentinel lymph node biopsy for breast cancer: a suitable alternative to routine axillary dissection in multi-institutional practice when optimal technique is used Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 18 13, 2560

McMasters,K.M.; Wong,S.L.; Tuttle,T.M.; Carlson,D.J.; Brown,C.M.; Dirk Noyes,R.; Glaser,R.L.; Vennekotter,D.J.; Turk,P.S.; Tate,P.S.; Sardi,A.; Edwards,M.J. 2000. Preoperative lymphoscintigraphy for breast cancer does not improve the ability to identify axillary sentinel lymph nodes Annals of Surgery, 231 5, 724

Tafra,L.; McMasters,K.M.; Whitworth,P.; Edwards,M.J. 2000. Credentialing issues with sentinel lymph node staging for breast cancer American Journal of Surgery, 180 4, 268

Whitworth,P.; McMasters,K.M.; Tafra,L.; Edwards,M.J. 2000. State-of-the-art lymph node staging for breast cancer in the year 2000 American Journal of Surgery, 180 4, 262

Wrightson,W.R.; Edwards,M.J.; McMasters,K.M. 2000. The role of the ultrasonically activated shears and vascular cutting stapler in hepatic resection The American Surgeon, 66 11, 1037

Yoshidome,H.; Miyazaki,M.; Shimizu,H.; Ito,H.; Nakagawa,K.; Ambiru,S.; Nakajima,N.; Edwards,M.J.; Lentsch,A.B. 2000. Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion Journal of hepatology, 33 1, 59

Klimberg,V.S.; Galandiuk,S.; Singletary,E.S.; Cohen,A.; Sener,S.; Talamonti,M.S.; Witt,T.R.; Niederhuber,J.E.; Edwards,M.J. 1999. Society of surgical oncology: statement on genetic testing for cancer susceptibilty. committee on issues and governmental affairs of the society of surgical oncology Annals of surgical oncology, 6 5, 507

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. 1999. Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2 Cancer immunology, immunotherapy : CII, 47 5, 243

Lentsch,A.B.; Yoshidome,H.; Kato,A.; Warner,R.L.; Cheadle,W.G.; Ward,P.A.; Edwards,M.J. 1999. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice Hepatology (Baltimore, Md.), 30 6, 1448

Lentsch,A.B.; Yoshidome,H.; Warner,R.L.; Ward,P.A.; Edwards,M.J. 1999. Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion Gastroenterology, 117 4, 953

McMasters KM, Martin KD, Edwards MJ 1999. Sentinel lymph node biopsy for pelvic malignancies J Pelvic Surg, 5 , 166

Polk,H.C.,Jr; Edwards,M.J. 1999. Post-perfusion recurrent melanoma Annals of surgical oncology, 6 6, 524

Wrightson,W.R.; Edwards,M.J.; McMasters,K.M. 1999. Primary squamous cell carcinoma of the breast presenting as a breast abscess The American Surgeon, 65 12, 1153

Yoshidome,H.; Edwards,M.J. 1999. An embryological perspective on congenital portacaval shunt: a rare anomaly in a patient with hepatocellular carcinoma The American Journal of Gastroenterology, 94 9, 2537

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. 1999. Interleukin-10 inhibits pulmonary nf-kappab activation and lung injury induced by hepatic ischemia-reperfusion The American Journal of Physiology, 277 5 Pt 1, L919

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. 1999. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappab Hepatology (Baltimore, Md.), 30 1, 203

Yoshidome,H.; Kato,A.; Miyazaki,M.; Edwards,M.J.; Lentsch,A.B. 1999. Il-13 activates stat6 and inhibits liver injury induced by ischemia/reperfusion The American journal of pathology, 155 4, 1059

Yoshidome,H.; Lentsch,A.B.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. 1999. Enhanced pulmonary expression of cxc chemokines during hepatic ischemia/reperfusion-induced lung injury in mice The Journal of surgical research, 81 1, 33

Yoshidome,H.; McMasters,K.M.; Edwards,M.J. 1999. Management issues regarding hepatic adenomatosis The American Surgeon, 65 11, 1070

Edwards,M.J. 1998. Access to quality cancer care: consensus statement of the american federation of clinical oncologic societies Annals of surgical oncology, 5 7, 657

Edwards,M.J. 1998. Surgical oncology Journal of the American College of Surgeons, 186 2, 222

Edwards,M.J.; Bonadonna,G.; Valagussa,P.; Gamel,J.W. 1998. End points in the analysis of breast cancer survival: relapse versus death from tumor Surgery, 124 2, 197

Edwards,M.J.; Gamel,J.W.; Feuer,E.J. 1998. Improvement in the prognosis of breast cancer from 1965 to 1984 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16 3, 1030

Edwards,M.J.; Gamel,J.W.; Vaughan,W.P.; Wrightson,W.R. 1998. Infiltrating ductal carcinoma of the breast: the survival impact of race Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16 8, 2693

Edwards,M.J.; Martin,K.D.; McMasters,K.M. 1998. Lymphatic mapping and sentinel lymph node biopsy in the staging of melanoma Surgical oncology, 7 1-2, 51

Ehringer,W.D.; Edwards,M.J.; Wintergerst,K.A.; Cox,A.; Miller,F.N. 1998. An increase in endothelial intracellular calcium and f-actin precedes the extravasation of interleukin-2-activated lymphocytes Microcirculation (New York, N.Y.: 1994), 5 1, 71

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Miller,F.N. 1998. N omega-nitro-l-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2 Journal of leukocyte biology, 63 1, 22

Lentsch,A.B.; Yoshidome,H.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. 1998. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and kc Hepatology (Baltimore, Md.), 27 4, 1172

Lentsch,A.B.; Yoshidome,H.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. 1998. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and kupffer cells Hepatology (Baltimore, Md.), 27 2, 507

McMasters,K.M.; Giuliano,A.E.; Ross,M.I.; Reintgen,D.S.; Hunt,K.K.; Byrd,D.R.; Klimberg,V.S.; Whitworth,P.W.; Tafra,L.C.; Edwards,M.J. 1998. Sentinel-lymph-node biopsy for breast cancer--not yet the standard of care The New England journal of medicine, 339 14, 990

Yoshidome H, Edwards MJ, Lentsch AB 1998. Protective effects of interleukin-10 on hepatic ischemia/reperfusion injury: Reduction of NF-kB and pro-inflammatory cytokine production Surgical Forum, 49 , 180

Edwards,M.J.; Israel,P.Z. 1997. Beyond the credentialing and privileging controversy surrounding image-guided breast biopsy. the rationale for a national registry for quantifying outcomes Bulletin of the American College of Surgeons, 82 6, 20

Edwards,M.J.; McMasters,K.M.; Acland,R.D.; Papp,K.K.; Garrison,R.N. 1997. Oral presentations for surgical meetings The Journal of surgical research, 68 1, 87

Edwards,M.J.; Nakagawa,K.; McMasters,K.M. 1997. En bloc pancreaticoduodenectomy and colectomy for duodenal neoplasms Southern medical journal, 90 7, 733

Ehringer,W.D.; Edwards,M.J.; Gray,R.D.; Miller,F.N. 1997. Bradykinin antagonizes the effects of alpha-thrombin Inflammation, 21 3, 279

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. 1997. Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation The American Journal of Physiology, 272 4 Pt 1, G727

Lentsch,A.B.; Nakagawa,K.; Yoshidome,H.; Gerassimides,A.; Miller,F.N.; Edwards,M.J. 1997. Distinct biological activities of recombinant forms of human interleukin-2 in vivo Cancer immunology, immunotherapy : CII, 43 6, 331

Sloan,D.A.; Donnelly,M.B.; Plymale,M.A.; Schwartz,R.W.; Edwards,M.J.; Singletary,S.E.; Evans,D.B.; Souba,W.W.; Gadd,M.; Bland,K.I. 1997. Improving residents' clinical skills with the structured clinical instruction module for breast cancer: results of a multiinstitutional study. breast cancer education working group Surgery, 122 2, 324

Sloan,D.A.; Donnelly,M.B.; Schwartz,R.W.; Plymale,M.A.; Strodel,W.E.; Kenady,D.E.; McGrath,P.C.; Edwards,M.J.; Singletary,S.E.; Evans,D.B.; Souba,W.W.; Bland,K.I. 1997. The multidisciplinary structured clinical instruction module as a vehicle for cancer education American Journal of Surgery, 173 3, 220

Yoshidome H, Lentsch AB, Miller FN, Miyazaki M, Edwards MJ 1997. Roles of macrophage inflammatory protein-2 and KC in hepatic ischemia reperfusion in mice Surgical Forum, 48 , 193

Anderson,J.A.; Lentsch,A.B.; Hadjiminas,D.J.; Miller,F.N.; Martin,A.W.; Nakagawa,K.; Edwards,M.J. 1996. The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in c57bl/6 mice The Journal of clinical investigation, 97 8, 1952

Edwards,M.J.; Anderson,J.A.; Angel,J.R.; Harty,J.I. 1996. Spontaneous regression of primary and metastatic renal cell carcinoma The Journal of urology, 155 4, 1385

Edwards,M.J.; Gable,D.R.; Lentsch,A.B.; Richardson,J.D. 1996. The rationale for esophagectomy as the optimal therapy for barrett's esophagus with high-grade dysplasia Annals of Surgery, 223 5, 585

Ehringer,W.D.; Edwards,M.J.; Miller,F.N. 1996. Mechanisms of alpha-thrombin, histamine, and bradykinin induced endothelial permeability Journal of cellular physiology, 167 3, 562

Gamel,J.W.; Edwards,M.J. 1996. Parametric models of therapeutic efficacy in breast cancer The New England journal of medicine, 334 19, 1270

Lentsch,A.B.; Edwards,M.J.; Miller,F.N. 1996. Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity The Journal of laboratory and clinical medicine, 128 1, 75

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Nakagawa,K.; Wellhausen,S.R.; Miller,F.N. 1996. Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in c3h/hen mice Journal of leukocyte biology, 60 1, 51

McMasters,K.M.; Edwards,M.J. 1996. Liver cryosurgery The Journal of the Kentucky Medical Association, 94 6, 222

Nakagawa,K.; Miller,F.N.; Sims,D.E.; Lentsch,A.B.; Miyazaki,M.; Edwards,M.J. 1996. Mechanisms of interleukin-2-induced hepatic toxicity Cancer research, 56 3, 507

Yoshidome H, Lentsch AB, Nakagawa K, Miller FN, Miyazaki M, Edwards MJ 1996. Preservation of cysteine at amino acid 125 in IL-2 is critical for the pentoxifylline inhibition of IL-2 toxicity Surgical Forum, 47 , 515

Acland RD, Edwards MJ, Papp KK 1995. Effective lecturing: Cardinal virtues, deadly sins Focus on Surgical Education, 13 , 29

Anderson,J.A.; Knott,A.W.; Wilson,M.A.; Garrison,R.N.; Sims,D.E.; Edwards,M.J. 1995. The effect of soluble tumor necrosis factor receptor-ii on endotoxin-mediated hemodynamic instability The Journal of surgical research, 58 1, 53

Anderson,J.A.; Woodcock,T.M.; Harty,J.I.; Knott,A.W.; Edwards,M.J. 1995. The effects of oral pentoxifylline on interleukin-2 toxicity in patients with metastatic renal cell carcinoma European journal of cancer (Oxford, England : 1990), 31A 5, 714

Nakagawa,K.; Miller,F.N.; Knott,A.W.; Edwards,M.J. 1995. Pentoxifylline inhibits fmlp-induced macromolecular leakage The American Journal of Physiology, 269 1 Pt 2, H239

Quinn,T.D.; Polk,H.C.,Jr; Edwards,M.J. 1995. Hyperthermic isolated limb perfusion increases circulating levels of inflammatory cytokines Cancer immunology, immunotherapy : CII, 40 4, 272

Theuer,C.J.; Wilson,M.A.; Spain,D.A.; Edwards,M.J.; Garrison,R.N. 1995. Alpha-adrenergic receptor antagonism prevents intestinal vasoconstriction but not hypoperfusion following resuscitated hemorrhage The Journal of surgical research, 59 2, 292

Anderson,J.A.; Miller,F.N.; Sims,D.E.; Edwards,M.J. 1994. Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cells The Journal of surgical research, 56 6, 485

Edwards,M.J. 1994. Breast conserving surgery for early cancer: who, when, where, and how? The Journal of the Kentucky Medical Association, 92 5, 176

Edwards,M.J.; Bentley,F.R. 1994. Major hepatic resection under total vascular exclusion with extracorporeal venovenous bypass The American Surgeon, 60 4, 231

Heniford,B.T.; Edwards,M.J.; Wilson,M.A.; Klar,E.A.; Doak,K.W.; Miller,F.N. 1994. Interleukin-8 suppresses the toxicity and antitumor effect of interleukin-2 The Journal of surgical research, 56 1, 82

Quinn,T.D.; Miller,F.N.; Wilson,M.A.; Garrison,R.N.; Anderson,J.A.; Lenz,L.G.; Edwards,M.J. 1994. Interleukin-2-induced lymphocyte infiltration of multiple organs is differentially suppressed by soluble tumor necrosis factor receptor The Journal of surgical research, 56 2, 117

Sims,D.E.; Miller,F.N.; Horne,M.M.; Edwards,M.J. 1994. Interleukin-2 alters the positions of capillary and venule pericytes in rat cremaster muscle Journal of submicroscopic cytology and pathology, 26 4, 507

Edwards,M.J.; Heniford,B.T.; Miller,F.N. 1993. Tumor necrosis factor mediates disseminated intravascular inflammation (dii) in the genesis of multiple organ edema The Journal of surgical research, 54 2, 140

Edwards,M.J.; Abney,D.L.; Heniford,B.T.; Miller,F.N. 1992. Passive immunization against tumor necrosis factor inhibits interleukin-2-induced microvascular alterations and reduces toxicity Surgery, 112 2, 480

Edwards,M.J.; Heniford,B.T.; Klar,E.A.; Doak,K.W.; Miller,F.N. 1992. Pentoxifylline inhibits interleukin-2-induced toxicity in c57bl/6 mice but preserves antitumor efficacy The Journal of clinical investigation, 90 2, 637

Edwards,M.J.; Heniford,B.T.; Miller,F.N. 1992. Mast cell degranulation inhibits il-2-induced microvascular protein leakage The Journal of surgical research, 52 5, 429

Edwards,M.J.; Miller,F.N.; Sims,D.E.; Abney,D.L.; Schuschke,D.A.; Corey,T.S. 1992. Interleukin 2 acutely induces platelet and neutrophil-endothelial adherence and macromolecular leakage Cancer research, 52 12, 3425

Heniford BT, Edwards MJ, Klar EA, Miller FN 1992. Interleukin-8 suppresses interleukin-2-induced toxicity Surgical Forum, 43 , 465

Broadwater,J.R.; Edwards,M.J.; Kuglen,C.; Hortobagyi,G.N.; Ames,F.C.; Balch,C.M. 1991. Mastectomy following preoperative chemotherapy. strict operative criteria control operative morbidity Annals of Surgery, 213 2, 126

Edwards,M.J.; Abney,D.L.; Miller,F.N. 1991. Pentoxifylline inhibits interleukin-2-induced leukocyte-endothelial adherence and reduces systemic toxicity Surgery, 110 2, 199

Edwards,M.J.; Schuschke,D.A.; Abney,D.L.; Miller,F.N. 1991. Interleukin-2 acutely induces protein leakage from the microcirculation The Journal of surgical research, 50 6, 609

Broadwater,J.R.; Henderson,M.A.; Bell,J.L.; Edwards,M.J.; Smith,G.J.; McCready,D.R.; Swanson,R.S.; Hardy,M.E.; Shenk,R.R.; Lawson,M. 1990. Outpatient percutaneous central venous access in cancer patients American Journal of Surgery, 160 6, 676

Edwards,M.J. 1990. Current management of soft tissue sarcomas The Journal of the Kentucky Medical Association, 88 9, 497

Edwards,M.J.; Soong,S.J.; Boddie,A.W.; Balch,C.M.; McBride,C.M. 1990. Isolated limb perfusion for localized melanoma of the extremity. a matched comparison of wide local excision with isolated limb perfusion and wide local excision alone Archives of surgery (Chicago, Ill.: 1960), 125 3, 317

Broadwater JR, Edwards MJ, Hohn D, Balch CM 1989. A formal curriculum for clinical research Focus on Surgical Education, 6 , 12

Edwards,M.J.; Balch,C.M. 1989. Surgical aspects of lymphoma Advances in Surgery, 22 , 225

Edwards,M.J.; Boddie,A.W.,Jr; Ames,F.C.; McBride,C.M. 1989. Isolated limb perfusion for stage i melanoma of the extremity: a comparison of melphalan and dacarbazine (dtic) Southern medical journal, 82 8, 985

Edwards,M.J.; Hirsch,R.M.; Broadwater,J.R.; Netscher,D.T.; Ames,F.C. 1989. Squamous cell carcinoma arising in previously burned or irradiated skin Archives of surgery (Chicago, Ill.: 1960), 124 1, 115

Siddik,Z.H.; Edwards,M.J.; Boddie,A.W. 1989. Isolated limb perfusion with chemotherapeutic agents for melanoma: a reevaluation of drug dosimetry European journal of cancer & clinical oncology, 25 10, 1393

Baldwin B, Edwards MJ, Romsdahl M 1988. Squamous cell carcinoma arising in recessive epidermolysis bullosa dystrophica Cancer Bulletin, 40 , 393

Bull,J.M.; Strebel,F.R.; Sunderland,B.A.; Bulger,R.E.; Edwards,M.; Siddik,Z.H.; Newman,R.A. 1988. O-(beta-hydroxyethyl)-rutoside-mediated protection of renal injury associated with cis-diamminedichloroplatinum(ii)/hyperthermia treatment Cancer research, 48 8, 2239

Edwards MJ, Siddik ZH 1988. Hyperthermic potentiation of carboplatin-induced cytotoxicity: Potential implications for isolated limb perfusion for melanoma Surgical Forum, 39 , 433

Edwards,M.J.; Broadwater,J.R.; Bell,J.L.; Ames,F.C.; Balch,C.M. 1988. Economic impact of reducing hospitalization for mastectomy patients Annals of Surgery, 208 3, 330

Edwards,M.J.; Richardson,J.D.; Klamer,T.W. 1988. Management of aortic prosthetic infections American Journal of Surgery, 155 2, 327

Baker, Jennifer E; Boudreau, Ryan M; Seitz, Aaron P; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J . Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era? Surgical infections, 19 8, 792-803

Hoehn, Richard S; Davis, Bradley R; Huber, Nathan L; Edwards, Michael J; Lungu, Douglas; Logan, Jocelyn M . A systematic approach to developing a global surgery elective. Journal of surgical education, 72 4, e15-20

Quillin, Ralph C; Pritts, Timothy A; Hanseman, Dennis J; Edwards, Michael J; Davis, Bradley R . How residents learn predicts success in surgical residency. Journal of surgical education, 70 6, 725-30