UC Receives $4.3 Million From NIH For Mouse Metabolic Phenotyping Center
CINCINNATI—Researchers at the University of
Cincinnati (UC) have been awarded a five-year, $4.3 million renewal
grant from the National Institutes of Health (NIH) to continue work
at the university’s Mouse Metabolic Phenotyping Center (MMPC)
in Reading, Ohio.
The MMPC is a NIH-sponsored resource that provides experimental
testing services to scientists studying diabetes, obesity, diabetic
complications and other metabolic diseases in mice; UC is one of
two of the original sites nationally to receive the renewed
"The grant is a great point of pride for my team and the
university. By awarding this grant, the NIH recognizes that our
contribution to diabetes and obesity research is strong and that
our staff is committed to promoting research for investigators
across the country,” says the center’s director Patrick
Tso, PhD, Mary Emery Professor of Pathology and Laboratory Medicine
UC College of Medicine.
At the center, researchers observe and report the various metabolic
and physiological functions of genetically-engineered mice sent to
UC from research institutions worldwide.
"We don’t generate the genetically modified mouse and we
don’t claim any credit for the outcomes,” Tso says,
citing the centers purpose as a way for investigators, especially
young investigators with limited research funding, to conduct
sophisticated phenotyping investigation in areas such as diabetes,
obesity and related metabolic diseases or conditions at a fraction
of the cost.
The MMPC program was established by the NIH for said purpose in
2001 to form a consortium of four centers including UC, from within
the U.S., both NIH and non-NIH funded. UC’s NIH funding was
renewed at NIH on March 14, 2016, and of the original four centers,
UC and Vanderbilt University are the only two centers to have
received continuous NIH funding. The consortium currently consists
of five centers.
The NIH grant award cites the UC MMPC as a "highly successful MMPC,
which has been thriving under the strong leadership of Dr. Patrick
Tso” and judged the overall merit of UC’s application
to be "Outstanding to Excellent.”
”The College of Medicine is proud to have such an
outstanding, talented group of investigators that not only perform
their own cutting edge research, but also facilitate investigation
and discovery by faculty around the country. We are grateful to Dr.
Tso for his exceptional leadership in sustaining this valuable
center,” says Melanie Cushion, PhD, senior associate dean of
research at the College of Medicine.
Other members of the UC center include: Sean Davidson, PhD,
professor, Philip Howles, PhD, associate professor, Min Liu,
PhD, professor, Laura Woollett, PhD, professor, all in the
University of Cincinnati College of Medicine’s Department of
Pathology and Laboratory Medicine’s and Steven Benoit, PhD,
associate professor, James Herman, PhD, professor, Yvonne
Ulrich-Lai, PhD, associate professor, Theresa Reyes, associate
professor, Stephen Woods, PhD, professor emeritus, all in the
college’s Department of Psychiatry of Behavioral
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