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Department of

Pharmacology & Systems Physiology 

Photo of  William Ball, PhD

William Ball, PhD

Professor, Pharmacology & Cell Biophysics

Education/Credentials
  • Doctoral Degree: University of California at Los Angeles
  • Master's Degree.: California State University at San Diego
  • Bachelor's Degree: San Diego State College

Contact Information
  • Cardiovascular Center
  • Room CVC 5939
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 4526700575
  • Office 513-558-2388
  • Fax 513-558-9969
  • Email william.ball@uc.edu

Peer Reviewed Publications

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Ball, W.J. Jr., Garbett, N.C , Tabet, M.R., Tabaja, N., Norman, A.B. 2014. The Re- Engineered Humanized anti-Cocaine Monoclonal Antibody h2E2: Analysis of its Thermo- and pH -Stability and Energetics of Ligand Bindings In preparation, ,

Felicia C.T. Gooden, Hanna Dasenbrock, Kelli Edwards, Michael R. Tabet, William J. Ball, and Andrew B. Norman 2014. The effects of humanized anti-cocaine monoclonal antibody h2E2 on distribution and metabolism of cocaine in vivo and in vitro. In Preparation, ,

Hanna N. Wetzel, Felicia C.T. Gooden, Michael R. Tabet, William J. Ball, Andrew B. Norman 2014. The effects of a humanized recombinant anti-cocaine monoclonal antibody on the disposition of cocaethylene in mice In Preparation., ,

Norman, Andrew B; Gooden, Felicia C T; Tabet, Michael R; Ball, William J 2014. A Recombinant Humanized Anti-cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats. Drug metabolism and disposition: the biological fate of chemicals, ,

Wetzel, Hanna N; Tabet, Michael R; Ball, William J; Norman, Andrew B 2014. The effects of a humanized recombinant anti-cocaine monoclonal antibody on the disposition of cocaethylene in mice. International immunopharmacology, 23 2, 387-90

Norman, Andrew B; Ball, William J 2012. Predicting the clinical efficacy and potential adverse effects of a humanized anticocaine monoclonal antibody. Immunotherapy, 4 3, 335-43

Lape, Michael; Paula, Stefan; Ball, William J 2010. A molecular model for cocaine binding by the immunotherapeutic human/mouse chimeric monoclonal antibody 2E2. European journal of medicinal chemistry, 45 6, 2291-8

Norman, Andrew B; Norman, Mantana K; Buesing, William R; Tabet, Michael R; Tsibulsky, Vladimir L; Ball, William J 2009. The effect of a chimeric human/murine anti-cocaine monoclonal antibody on cocaine self-administration in rats. The Journal of pharmacology and experimental therapeutics, 328 3, 873-81

Seligson, D., Rajasekaran, S. A., Yu, H., Liu, X., Eeva, M., Tze, S., Ball, W. J. Jr., Horvath, S., deKernin, J. and Rajasekaran, A. K. 2008. Na, K-ATPase α1-Subunit Predicts Survival in Renal Clear Cell Carcinoma. J. Urology, 179 , 338-345

Norman, A.B., Tabet, M.R., Norman, M.K., Buesing, W.R., Pesce, A.J. and Ball, W.J. 2007. A Chimeric human/murine Anti-cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Mice. J. Pharmacology Experimental Therapeutics, 320 , 145-153

Norman, Andrew B; Tabet, Michael R; Norman, Mantana K; Buesing, William R; Pesce, Amadeo J; Ball, William J 2007. A chimeric human/murine anticocaine monoclonal antibody inhibits the distribution of cocaine to the brain in mice. The Journal of pharmacology and experimental therapeutics, 320 1, 145-53

Keenan, S.M., DeLisle, R.K., Paula, S., Welsh, W.J. and Ball, W.J. 2005. Elucidation of the Na+, K+-ATPase Digitalis Binding Site J. Mol. Graphics & Modeling., 23 , 465-475

Keenan, Susan M; DeLisle, Robert K; Welsh, William J; Paula, Stefan; Ball, William J 2005. Elucidation of the Na+, K+-ATPase digitalis binding site. Journal of molecular graphics & modelling, 23 6, 465-75

Paula, S., Monson, N. and Ball, W. J. Jr. 2005. Molecular Modeling of Cardiac Glycoside Binding to the Human Sequence Monoclonal Antibody 1B3. Proteins: Structure, Function and Bioinform., 60 , 382-391

Paula, S., Tabet, M. R. and Ball, W. J. Jr. 2005. Interactions between Cardiac Glycosides and Na/K-ATPase: 3D Structure-Activity Relationship Models for Ligand Binding to the E2-Pi form of the Enzyme versus Activity Inhibition. Biochem., 44 , 498-510

Paula, Stefan; Monson, Nancy; Ball, William James 2005. Molecular modeling of cardiac glycoside binding by the human sequence monoclonal antibody 1B3. Proteins, 60 3, 382-91

Paula, Stefan; Tabet, Michael R; Ball, William James 2005. Interactions between cardiac glycosides and sodium/potassium-ATPase: three-dimensional structure-activity relationship models for ligand binding to the E2-Pi form of the enzyme versus activity inhibition. Biochemistry, 44 2, 498-510

Paula, S. and Ball, W. J. Jr. 2004. Molecular Determinants of Thapsigargin Binding by SERCA Ca2+-ATPAse: A Computational Docking Study. Proteins: Structure, Function and Bioinform., 56 , 595-606

Paula, S., Tabet, M.R., Farr, C.D., Norman, A.B. and Ball, W.J. 2004. 3D-QSAR Modeling of Cocaine Binding by a Novel Human Antibody. J. Medicinal Chemistry, 47 , 133-142

Paula, Stefan; Ball, William James 2004. Molecular determinants of thapsigargin binding by SERCA Ca2+-ATPase: a computational docking study. Proteins, 56 3, 595-606

Paula, Stefan; Tabet, Michael R; Farr, Carol D; Norman, Andrew B; Ball, W James 2004. Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody. Journal of medicinal chemistry, 47 1, 133-42

Ball, W James; Farr, Carol D; Paula, Stefan; Keenan, Susan M; Delisle, Robert K; Welsh, William J 2003. Three-dimensional structure-activity relationship modeling of digoxin inhibition and docking to Na+,K+-ATPase. Annals of the New York Academy of Sciences, 986 , 296-7

Espineda, C., Seligson, D., Ball, W.J., Jr., Rao, J.Y., Palotie, A., Shi, T., Huang, Y., Horvath, S. and Rajasekaran, A.K. 2003. Analysis of the Clinical Significance of Na,K-ATPase - and -subunit Expression Profiles of the Bladder Cancer using Tissue Microassays Cancer, 97 , 1859-1868

Paula, S., Tabet, M., Keenan, S., Welsh, W. and Ball, W.J., Jr. 2003. 3D Structure-Activity Relationship Modeling of Cocaine Binding to Two Monoclonal Antibodies by Comparative Molecular Field Analysis. J. Mol. Biol., 325 , 515-530

Paula, Stefan; Tabet, Michael R; Keenan, Susan M; Welsh, William J; Ball, W James 2003. Three-dimensional structure-activity relationship modeling of cocaine binding to two monoclonal antibodies by comparative molecular field analysis. Journal of molecular biology, 325 3, 515-30

Farr, C.D., Burd, C., Tabet, M.R., Wang, X., Welsh, W.J. and Ball, W. J., Jr. 2002. Three-Dimensional Quantitative Structure-Activity Relationship of the Inhibition of the Na+,K+-ATPase by Cardiotonic Steroids Using Comparative Molecular Field Analysis. Biochemistry, 41 , 1137-1148

Farr, C.D., Tabet, M.R., Fishwild, D.M., Wang, X., Nair, A.C., Welsh, W.J. and Ball, W. J., Jr. 2002. Three-Dimensional Quantitative Structure Activity Relationship Analysis of Ligand Binding to Human Sequence Anti-Digoxin Monoclonal Antibodies Using Comparative Molecular Field Analysis J. Medicinal Chemistry, 45 , 3257-3270

Farr, Carol D; Burd, Craig; Tabet, Michael R; Wang, Xia; Welsh, William J; Ball, William J 2002. Three-dimensional quantitative structure-activity relationship study of the inhibition of Na(+),K(+)-ATPase by cardiotonic steroids using comparative molecular field analysis. Biochemistry, 41 4, 1137-48

Farr, Carol D; Tabet, Michael R; Ball, William J; Fishwild, Dianne M; Wang, Xia; Nair, Anil C; Welsh, William J 2002. Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis. Journal of medicinal chemistry, 45 15, 3257-70

Rajasekaran, S A; Palmer, L G; Quan, K; Harper, J F; Ball, W J; Bander, N H; Peralta Soler, A; Rajasekaran, A K 2001. Na,K-ATPase beta-subunit is required for epithelial polarization, suppression of invasion, and cell motility. Molecular biology of the cell, 12 2, 279-95

Rajasekaran, S.A., Palmer, L.G., Bander, N., Ball, W. J., Jr., Quan, K., Harper, J., Sober, A. and Rajasekaran, A.K. 2001. Na, K-ATPase -Subunit is Required for Epithelial Polarization, suppression of Invasion and Cell Mobility. Mol. Biology Cell, 12 2, 279-295

Ball, W J; Wang, Z; Malik, B; Kasturi, R; Dey, P; Short, M K; Margolies, M N 2000. Selection of peptidic mimics of digoxin from phage-displayed peptide libraries by anti-digoxin antibodies. Journal of molecular biology, 301 1, 101-15

Ball, W. J., Jr., Wang, Z.M., Malik, B., Kasturi, R., Dey, P., Short, M. and Margolies, M. 2000. Selection of Peptidic Mimics of Digoxin from Combinatorial Peptide Libraries by Anti-digoxin Antibodies J. Mol. Biol., 301 , 101-115

Ball, W J; Kasturi, R; Dey, P; Tabet, M; O'Donnell, S; Hudson, D; Fishwild, D 1999. Isolation and characterization of human monoclonal antibodies to digoxin. Journal of immunology (Baltimore, Md. : 1950), 163 4, 2291-8

Ball, W. J., Jr., Kasturi, R., Dey, P., O’Donnell, S., Hudson, D. and Fishwild, D. 1999. Isolation and Characterization of Human Monoclonal Antibodies to Digoxin J. Immunology, 163 , 2291-2298

Rajasekaran, S A; Ball, W J; Bander, N H; Liu, H; Pardee, J D; Rajasekaran, A K 1999. Reduced expression of beta-subunit of Na,K-ATPase in human clear-cell renal cell carcinoma. The Journal of urology, 162 2, 574-80

Rajasekaran, S., Ball, W.J., Bander, N.H., Liu, N.H., Pardee, J.D. and Rajasekaran, A.K. 1999. Reduced Expression of -Subunit of Na+,K+-ATPase in Human Clear-Cell Renal-Cell Carcinoma J. Urology, 162 , 574-580

Kasturi, R., Yuan, J., McLean, L., Margolies, M. and Ball, W. J., Jr. 1998. Identification of a Model Cardiac Glycoside Receptor. Biochemistry, 37 , 6658-6666

Kasturi, R; Yuan, J; McLean, L R; Margolies, M N; Ball, W J 1998. Identification of a model cardiac glycoside receptor: comparisons with Na+,K+-ATPase. Biochemistry, 37 19, 6658-66

Kasturi, R; McLean, L R; Margolies, M N; Ball, W J 1997. High affinity anti-digoxin antibodies as model receptors for cardiac glycosides. Comparisons with Na+,K(+)-ATPase. Annals of the New York Academy of Sciences, 834 , 634-6

Amler, E., Abbott, A., Malak, H., Lakowicz, J. and Ball, W. J., Jr. 1996. The Carbohydrate Moieties of the ß subunit of Na+,K+ ATPase: Their Lateral Motions and Proximity to the Cardiac Glycoside Site. Biophys. J., 70 , 182-193

Amler, E; Abbott, A; Malak, H; Lakowicz, J; Ball, W J 1996. The carbohydrate moieties of the beta-subunit of Na+, K(+)-ATPase: their lateral motions and proximity to the cardiac glycoside site. Biophysical journal, 70 1, 182-93

Therien, A G; Nestor, N B; Ball, W J; Blostein, R 1996. Tissue-specific versus isoform-specific differences in cation activation kinetics of the Na,K-ATPase. The Journal of biological chemistry, 271 12, 7104-12

Therien, A.G., Nestor, N.B., Ball, W. J., Jr. and Blostein, R. 1996. Tissue-Specific Versus Isoform-Specific Differences in Cation Activation Kinetics of the Na+,K+-ATPase. J. Biol. Chem., 271 , 7104-7112

Carl, S L; Felix, K; Caswell, A H; Brandt, N R; Ball, W J; Vaghy, P L; Meissner, G; Ferguson, D G 1995. Immunolocalization of sarcolemmal dihydropyridine receptor and sarcoplasmic reticular triadin and ryanodine receptor in rabbit ventricle and atrium. The Journal of cell biology, 129 3, 673-82

Carl, S.L., Felix, K., Caswell, A.H., Brandt, N.R., Ball, W.J., Vaghy, P., Meissner, G., and Ferguson, D.G. 1995. Immunolocalization of Sarcolemmal Dihydropyridine Receptor and Sarcoplasmic Reticular Triadin and Ryanodine Receptor in Rabbit Ventricle and Atrium. J. Cell Biology, 129 , 673-682

Sun, Y. and Ball, W. J., Jr. 1994. Identification of Antigenic Sites on the Na+,K+-ATPase * Subunit: Their sequences and the affects of thiol reduction upon their structure. Biochim. Biophys. Acta, 1207 , 236-248

Sun, Y; Ball, W J 1994. Identification of antigenic sites on the Na+/K(+)-ATPase beta-subunit: their sequences and the effects of thiol reduction upon their structure. Biochimica et biophysica acta, 1207 2, 236-48

Abbott, A. and Ball, W. J., Jr. 1993. The Epitope on for the Inhibitory Antibody M7 PB E9 Contains Ser 646 and Asp 652 of the Sheep Na+,K+ ATPase, * Subunit. Biochemistry, 32 , 3511-3518

Abbott, A; Ball, W J 1993. The epitope for the inhibitory antibody M7-PB-E9 contains Ser-646 and Asp-652 of the sheep Na+,K(+)-ATPase alpha-subunit. Biochemistry, 32 13, 3511-8

Malik, B., Jamieson, G., and Ball, W.J. 1993. Identification of the Amino Acids Comprising a Surface Exposed Epitope Within the Nucleotide-Binding Domain of the Na+,K+-ATPase Using a Random Peptide Library. Protein Sciences, 2 , 2103-2111

Malik, B; Jamieson, G A; Ball, W J 1993. Identification of the amino acids comprising a surface-exposed epitope within the nucleotide-binding domain of the Na+,K(+)-ATPase using a random peptide library. Protein science : a publication of the Protein Society, 2 12, 2103-11

Abbott, A. and Ball, W. J., Jr. 1992. The Inhibitory Monoclonal Antibody M7 PB E9 Stabilizes the E2 Conformational States of Na+,K+ ATPase. Biochemistry., 31 , 11236-11243

Abbott, A; Ball, W J 1992. The inhibitory monoclonal antibody M7-PB-E9 stabilizes E2 conformational states of Na+,K(+)-ATPase. Biochemistry, 31 45, 11236-43

Amler, E., Abbott, A. and Ball, W. J., Jr. 1992. Structural Dynamics and Oligomeric Interactions of Na+,K+ ATPase as Monitored Using Fluorescence Energy Transfer Biophys. J., 61 , 553-568

Amler, E; Abbott, A; Ball, W J 1992. Structural dynamics and oligomeric interactions of Na+,K(+)-ATPase as monitored using fluorescence energy transfer. Biophysical journal, 61 2, 553-68

Ball, W J; Abbott, A; Sun, Y; Malik, B 1992. Monoclonal antibodies and the identification of functional regions of the Na+,K(+)-ATPase. Annals of the New York Academy of Sciences, 671 , 436-9

Incerpi, S., Jefferson, J.R., Wood, W.G., Ball, W.J. and Schroeder, F. 1992. Na+ Pump and Plasma Membrane Structure in L Cell Fibroblasts Expressing Rat Liver Fatty Acid Binding Protein. Archives of Biochem. Biophys., 298 1, 35-42

Incerpi, S; Jefferson, J R; Wood, W G; Ball, W J; Schroeder, F 1992. Na pump and plasma membrane structure in L-cell fibroblasts expressing rat liver fatty acid binding protein. Archives of biochemistry and biophysics, 298 1, 35-42

Sun, Y. and Ball, W. J., Jr. 1992. Determination of Na+,K+ ATPase * and ß isoforms and Kinetic Properties in Mammalian Liver. Amer. J. Physiol., 262 , C1491-C1499

Sun, Y; Ball, W J 1992. Determination of Na(+)-K(+)-ATPase alpha- and beta-isoforms and kinetic properties in mammalian liver. The American journal of physiology, 262 6 Pt 1, C1491-9

Abbott, A J; Amler, E; Ball, W J 1991. Immunochemical and spectroscopic characterization of two fluorescein 5'-isothiocyanate labeling sites on Na+,K(+)-ATPase. Biochemistry, 30 6, 1692-701

Abbott, A., Amler, E. and Ball, W. J., Jr. 1991. Spectroscopic Characterization of Two FITC Labeling Sites on Na+,K+ ATPase and Their Environments Biochemistry, 30 6, 1692-1701

Ting Beall, H.P., Beall, H.C., Hastings, D.F., Friedman, M.L. and Ball, W. J., Jr. 1990. Identification of Monoclonal Antibody Binding Domains on Na+,K+ ATPase by Immunoelectron Microscopy. FEBS Letters, 265 , 121-125

Ting-Beall, H P; Beall, H C; Hastings, D F; Friedman, M L; Ball, W J 1990. Identification of monoclonal antibody binding domains of Na+,K(+)-ATPase by immunoelectron microscopy. FEBS letters, 265 1-2, 121-5

Friedman, M L; Ball, W J 1989. Determination of monoclonal antibody-induced alterations in Na+/K+-ATPase conformations using fluorescein-labeled enzyme. Biochimica et biophysica acta, 995 1, 42-53

Friedman, M. and Ball, W. J., Jr. 1989. Determination of Monoclonal Antibody Induced Alterations in Na+,K+ ATPase Conformation Using Fluorescein labeled Enzyme. Biochim. Biophys. Acta, 995 , 42-53

Ball, W J; Kirley, T L; Lane, L K 1988. Preparation of antibodies to Na+,K+-ATPase and its subunits. Methods in enzymology, 156 , 87-101

Schwartz, A; Grupp, G; Wallick, E; Grupp, I L; Ball, W J 1988. Role of the Na+K+-ATPase in the cardiotonic action of cardiac glycosides. Progress in clinical and biological research, 268B , 321-38

Ball, W J; Friedman, M L 1987. Immunochemical evidence that the FITC-labeling site on Na+,K+-ATPase is not the ATP binding site. Biochemical and biophysical research communications, 148 1, 246-53

Ball, W J; Loftice, C D 1987. Immunochemical studies of (Na+ + K+)-ATPase using site-specific, synthetic peptide directed antibodies. Biochimica et biophysica acta, 916 1, 100-11

Ball, W. J., Jr. and Friedman, M.L. 1987. Immunochemical Evidence that the FITC Labeling Site on Na+,K+ ATPase is Not the ATP Binding Site Biochem. Biophys. Res. Commun., 148 , 246-253

Ball, W. J., Jr. and Loftice, C.D. 1987. Immunochemical Studies of (Na++K+) ATPase Using Site Specific Synthetic Peptide Directed Antibodies Biochim. Biophys. Acta., 916 , 100-111

Ball, W J 1986. Uncoupling of ATP binding to Na+,K+-ATPase from its stimulation of ouabain binding: studies of the inhibition of Na+,K+-ATPase by a monoclonal antibody. Biochemistry, 25 22, 7155-62

Ball, W J; Lane, L K 1986. Immunochemical comparison of cardiac glycoside-sensitive (lamb) and -insensitive (rat) kidney (Na+ + K+)-ATPase. Biochimica et biophysica acta, 873 1, 79-87

Ball, W. J., Jr. 1986. Uncoupling of ATP Binding to Na+,K+ ATPase from its Stimulation of Ouabain Binding Biochemistry, 25 , 7155-7162

Ball, W. J., Jr. and Lane, L.K. 1986. Immunochemical Comparison of Cardiac Glycoside Sensitive (lamb) and Insensitive (rat) Kidney Na+,K+ ATPases Biochim. Biophys. Acta, 873 , 79-87

Lane, L K; Kirley, T L; Ball, W J 1986. Structural studies on H+,K+-ATPase: determination of the NH2-terminal amino acid sequence and immunological cross-reactivity with Na+,K+-ATPase. Biochemical and biophysical research communications, 138 1, 185-92

Lane, L.K., Kirley, T.L. and Ball, W. J., Jr. 1986. Structural Studies on H+,K+ ATPase: Determination of the NH2 Terminal Amino Acid Sequence and Immunological Cross Reactivity with Na+,K+ ATPase Biochim. Biophys. Res. Comm., 138 , 185-192

Ball, W J 1984. Immunochemical characterization of a functional site of (Na+,K+)-ATPase. Biochemistry, 23 10, 2275-81

Ball, W. J., Jr. 1984. Immunochemical Characterization of a Functional Site of Na+,K+ ATPase Biochemistry, 23 , 2275-2281

Ball, W J; Collins, J H; Lane, L K; Schwartz, A 1983. Studies of the antigenic properties of the catalytic and glycoprotein subunits of Na+,K+-ATPase. Archives of biochemistry and biophysics, 221 2, 371-80

Ball, W. J., Jr., Collins, J.H., Lane, L.K. and Schwartz, A 1983. The Antigenic Properties of the * , ß , , Components of Na+,K+ ATPase, Current Topics in Membranes and Transport (Ed. F. Bronner and A. Kleinzeller) Academic Press, 19 , 781-785

Ball, W. J., Jr., Collins, J.H., Lane, L.K. and Schwartz, A. 1983. Studies of the Antigenic Properties of the Catalytic and Glycoprotein Subunits of Na+,K+ ATPase Arch. Biochem. Biophys., 221 , 371-380

Collins, J H; Zot, A S; Ball, W J; Lane, L K; Schwartz, A 1983. Tryptic digest of the alpha subunit of lamb kidney (Na+ + K+)-ATPase. Biochimica et biophysica acta, 742 2, 358-65

Collins, J.H., Zot, A.S., Ball, W. J., Jr., Lane, L.K. and Schwartz, A. 1983. Structure of Lamb Kidney Na+,K+ ATPase: Tryptic Digest of the * Subunit Biochim. Biophys. Acta, 742 , 358-365

Ball, W J; Schwartz, A 1982. Studies of the antigenic properties of sheep kidney Na+,K+-ATPase. Archives of biochemistry and biophysics, 217 1, 110-9

Ball, W J; Schwartz, A; Lessard, J L 1982. Isolation and characterization of monoclonal antibodies to (Na+ + K+)-ATPase. Biochimica et biophysica acta, 719 3, 413-23

Ball, W. J., Jr. and Schwartz, A. 1982. Studies of the Antigenic Properties of Sheep Kidney Na+,K+ ATPase Arch. Biochem. Biophys., 217 , 110-119

Ball, W. J., Jr., Schwartz, A. and Lessard, J. 1982. Isolation and Characterization of monoclonal antibodies to Na+,K+ ATPase Biochim. Biophys. Acta, 719 , 413-423

Ball, W J; Tse-Eng, D; Wallick, E T; Bilezikian, J P; Schwartz, A; Butler, V P 1981. Effect of quinidine on the digoxin receptor in vitro. The Journal of clinical investigation, 68 4, 1065-74

Ball, W. J., Jr., Tse Eng, D., Wallick, E. T., Bilezikjian, J. P., Schwartz, A. and Butler, V. P., Jr. 1981. Effect of Quinidine on the Digoxin Receptor In Vitro J. Clin. Invest., 68 , 1065-1074

Schwartz, A., Adams, R. J., Ball, W. J., Jr., Collins, J. H., Gupte, S., Lane, L. K. and Wallick, E. T. 1980. Structure, Function and Regulation of Kidney Na,K ATPase Inter. J. Biochem., 12 , 287-293

Schwartz, A; Adams, R J; Ball, W J; Collins, J H; Gupte, S S; Lane, L K; Reeves, A S; Wallick, E T 1980. Structure, function and regulation of Na-K-ATPase. The International journal of biochemistry, 12 1-2, 287-93

Ball, W J; Balis, M E 1976. Changes in ornithine decarboxylase activity in rat intestines during aging. Cancer research, 36 9 pt.1, 3312-6

Ball, W J; Salser, J S; Balis, M E 1976. Biochemical changes in preneoplastic rodent intestines. Cancer research, 36 7 PT 2, 2686-9

Ball, W. J., Jr. and Balis, M. E. 1976. Changes in Ornithine Decarboxylase Activity in Rat Intestines During Aging Cancer Res, 36 , 3312-3316

Ball, W. J., Jr., Salser, J. S. and Balis, M. E. 1976. Biochemical Changes in Preneoplastic Rodent Intestines Cancer Res., 36 , 2686-2689

Salser, J S; Ball, W J; Balis, M E 1976. Biochemical changes in premalignant intestines. Cancer research, 36 9 PT 2, 3495-8

Salser, J. S., Ball, W. J., Jr. and Balis, M. E. 1976. Biochemical Changes in Premalignant Intestine Cancer Res., 36 , 3494-3498

Ball, W J; Atkinson, D E 1975. Adenylate energy charge in Saccharomyces cerevisiae during starvation. Journal of bacteriology, 121 3, 975-82

Ball, W J; Csurny, R; Moller, M; Balis, M E 1975. Lack of effect of portacaval shunt on ornithine decarboxylase activity in regenerating rat liver. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 150 2, 380-4

Ball, W. J., Jr. and Atkinson, D. E. 1975. Adenylate Energy Charge in Saccharomyces cerevisiae During Starvation J. Bacteriol., 121 , 975-982

Ball, W. J., Jr., Csurny, R., Moller, M. and Balis, M. E. 1975. Lack of Effect of Portacaval Shunt on Ornithine Decarboxylase Activity in Regenerating Rat Liver Proc. Exp. Biol. Med., 150 , 380-384

Balis, M. E., Ball, W. J., Jr., Salser, J. S. and Yip, L. C 1974. Effect of Drugs on Cells at Various Stages of Differentiation in Intestinal Epithelium In: Priorities in Perinatal Pharmacology, Dancis J. and Hwang, J. D. eds., Raven press, ,

Stewart, C J; Thomas, J O; Ball, W J; Aguirre, A R 1968. Coenzyme A analogs. 3. The chemical synthesis of desulfopantetheine 4'-phosphate and its enzymatic conversion to desulfo-coenzyme A. Journal of the American Chemical Society, 90 18, 5000-4

Stewart, C. J., Thomas, J. O., Ball, W. J., Jr. and Aguirre, A. J 1968. Coenzyme A Analogs. III. J. Amer. Chem. Soc., 90 , 5000-5004

Stewart, C. J. and Ball, W. J 1966. Coenzyme A Analogs. II. Biochemistry, 5 , 3833-3836

Published Abstracts

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Fishwild, D., O’Donnell, S., Hudson, D., Deshpande, U., Qin, S., Mackay, C. and Ball, W. 1998. Human IgGk Antigen-specific High Affinity Monoclonal Antibodies from Transgenic Mice The FASEB Journal, 12 4, p. A309


Balshaw, D.M. and Ball, W.J., Jr. 1996. Conformational Changes as Determinants of the Sensitivity of the Sodium/Potassium ATPase to the Cardiac Glycosides. Biophys. J., 70 2, A326


Carl, S.L., Felix, K., Caswell, A.H., Brandt, N.R., Ball, W.J. Jr., Vaghy, P.L., Meissner, G. and Ferguson, D.G. 1996. Immunolocalization of DHP Receptors, Ryanodine receptors and Triadin, in Adult Rabbit Atrium and Ventricle Biophy. J., 62 2,


Therien, A.G., Ball, W.J. and Blostein, R. 1995. Tissue-specific Versus Isoform Specific Differences in Cation Activation Kinetics of the Na+,K+-ATPase. Biophys. J., 68 , A307


Caswell, A., Ball, W.J., Meissner, G., Brandt, W., Branschwig, J., Vaghy, P. and Ferguson, D. 1992. Immunofluorescence Localization of Triadin, DHP Receptors and Ryanodine Receptors in Skeletal and Heart Muscle. FASEB J., 6 Abst. 921, A161


Ball, W.J., Jr. and Schwartz, A. 1980. Studies of the Antigenic Properties of Na+,K+ ATPase Dependent ATPase Fed. Proc., 39 , 1676


Ball, W.J., Jr., Tse Eng, D., Bilezikian, J.P., Wallick, E.T., Schwartz, A. and Butler, V.P., Jr. 1979. Studies of a Quinidine Digoxin Interaction Fed. Proc., 38 3, 1042