Find a Clinical Trial
Participation in a Clinical Trial
The involvement of UC and its neurology physicians in research studies is crucial to understanding diseases and developing new ways to understand, prevent or treat health problems.
Research studies, or trials as they are often called, depend on volunteers who agree to be part of carefully controlled tests that measure the effects of medications, medical treatments or devices. By volunteering, you can further medical knowledge and potentially help others.
The UC Neurology Department is conducting the following clinical trials:
Stroke | Epilepsy | Multiple Sclerosis | Neuromuscular | Parkinson's/Movement Disorders | Headache | Pediatric Neurology
Stroke Research
Genetic and Environmental Risk Factors of Hemorrhagic Stroke (GERFHS) – Coordinating Center
Funded by: NINDS/NIH
Principal Investigator: Daniel Woo, MD
Study Status: Active, Recruiting
Contact: Mary Haverbusch, RN: 513-558-3992, Mary.Haverbusch@uc.edu
A grant under the NINDS’ Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) program
Funded by: NINDS/NIH
Principal Investigator: Joseph Broderick, MD
Study Status: Active, Recruiting
Contact: Emily Goodall, RN: 513-558-3072, Emily.Goodall@uc.edu
The Spot Sign for Predicting and Treating Intracerebral Hemorrhage Growth (STOP-IT) – Coordinating Center
Funded by: NIH/NINDS
Principal Investigator: Matthew Flaherty, MD
Study Status: Active, Recruiting
Contact: Janice Carrozzella, RN, BA, CCRA, CCRC: 513-475-8793, Janice.Carrozzella@uc.edu
Ethnic/Racial Variations with Intracerebral Hemorrhage (ERICH)
Funded by: NINDS/National Institutes of Health
Principal Investigator: Daniel Woo, MD
Study Status: Active, Recruiting
Contact: Jennifer Osborne, RN: 513-558-4241, jennifer.osborne@uc.edu
Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke Trial (POINT)
Funded by: NINDS/National Institutes of Health through NETT (Neurological Emergencies Treatment Trials) Network
Principal Investigator: Dawn Kleindorfer, MD
Study Status: Active, Recruiting
Contact: Irene Ewing, RN: 513-558-2430, irene.ewing@uc.edu
Stroke Hyperglycemic Insulin Network Effort (SHINE) Trial
Funded by: NINDS/National Institutes of Health through NETT (Neurological Emergencies Treatment Trials) Network
Principal Investigator: Opeolu Adeoye, MD
Study Status: Active, Recruiting
Contact: Irene Ewing, RN: 513-558-2430, irene.ewing@uc.edu
Penumbral Relation to Clinical Outcome and Time (PREDICT) Study
Funded by: ARRS Scholarship Grant
Principal Investigator: Pooja Khatri, MD
Study Status: Active, Recruiting
Contact: Emily Goodall, RN: 513-558-3072, emily.goodgall@uc.edu
Epilepsy Research
Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: single-dose open label 6-period replicate design (single-dose study)
Funded by: University of Cincinnati American Epilepsy Society, Epilepsy Foundation
Primary Investigator: Michael Privitera, MD
Study Status: Active, Recruiting starting March 2013
Contact: Donna Schwieterman: 513-475-8781, schwied@uc.edu
Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Chronic-dose 4-period replicate design (chronic dose)
Funded by: University of Cincinnati American Epilepsy Society, Epilepsy Foundation
Primary Investigator: Michael Privitera, MD
Study Status: Active, Recruiting
Contact: Donna Schwieterman: 513-475-8781, schwied@uc.edu
Stress Related Seizures Database
Funded by: Pamela and Charles L. Shor Foundation for Epilepsy Research
Primary Investigator: Michael Privitera, MD
Study Status: Active, Recruiting
Contact: Donna Schwieterman: 513-475-8781, schwied@uc.edu
Stress Management for Living with Epilepsy (SMILE)
Funded by: Charles L. Shor Foundation
Primary Investigator: Michael Privitera, MD
Study Status: Active, Recruiting
Contact: Adrienne Fleck, RN: 513-558-3726, adrienne.fleck@uc.edu
Multiple Sclerosis Research
A Phase 1b, Dose-Escalating, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Eficacy of Subcutaneous ELND002 in Patients with Secondary Progressive or Relapsing Remitting Multiple Sclerosis
Principal Investigator: Maria Melanson, MD
Study Status: Active, Not Recruiting
Contact: Judy Morgan: 513-475-8741, morganjd@uc.edu
An Open-Label, Long-Term, Follow-Up Study of Subcutaneous ELND002 in Patients with Relapsing Forms of Multiple Sclerosis
Principal Investigator: Maria Melanson, MD
Study Status: Active, Not Recruiting
Contact: Judy Morgan: 513-475-8741, morganjd@uc.edu
JCV Antibody Program in Patients with Relapsing Multiple Sclerosis Receiving or Considering Treatment with Tysabri: STRATIFY-2
Principal Investigator: Maria Melanson, MD
Study Status: Active, Not Recruiting
Contact: Judy Morgan: 513-475-8741, morganjd@uc.edu
Neuromuscular Research
National Registry of Veterans with Amyotrophic Lateral Sclerosis
Funded by: Department of Veterans Affairs
Principal Investigator: Laura Sams, MD
Contact: VA Neurology: 513-475-6318
ALS research group DNA banking study
Funded by: NIH
Principal Investigator: Laura Sams, MD
Contact: UC Health Neurology: 513-475-8730
Movement Disorders and Parkinson's Disease Research
Psychogenic Tremor: Functional Magnetic Resonance Study of Emotional Processing
Funded by: NIH
Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Erin Neefus, BS: 513-558-6555, erin.neefus@uc.edu
Sensory and Emotional Processing in Psychogenic Dystonia: a Functional Magnetic Resonance Imaging Study
Funded by: NIH
Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Erin Neefus, BS: 513-558-6555, erin.neefus@uc.edu
Validation of a Non-Motor Fluctuation Assessment instrument (NoMoFA) for Parkinson's Disease
Funded by: Unfunded
Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Jaya Mishra, PhD: 513-558-0169, jaya.mishra@uc.edu
The PaGeR Study: Using Multiplex Families to Map Genes that Modify Sesceptiblity and Age at Onset of Parkinson's Disease
Funded by: NIH/Univeristy of Washington
Site Principal Investigator: Fredy J. Revilla, MD
Study Status: Active, Recruiting
Contact: Jaya Mishra, PhD: 513-558-0169, jaya.mishra@uc.edu
PANUC Study Core
Funded by: NIH/Univeristy of Washington
Site Principal Investigator: Fredy J. Revilla, MD
Study Status: Active, Recruiting
Contact: Jaya Mishra, PhD: 513-558-0169, jaya.mishra@uc.edu
Tremor Retrainment as a Therapeutic Strategy for Patients with Psychogenic Tremor: A Proof-Of-Concept Feasibility Study
Funded by: Cleveland Medical Devices, Inc.
Site Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Jaya Mishra, PhD: 513-558-0169, jaya.mishra@uc.edu
A multi-centre, randomized, double-blind, placebo-controlled, parallel-group, multiple oral dose study to assess the efficacy, safety, and tolerability of AQW051 in reducing L-dopa induced dyskinesias in Parkinson’s patients with moderate to severe L-dopa induced dyskinesias
Funded by: Novartis
Site Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Erin Neefus, BS: 513-558-6555, erin.neefus@uc.edu
The Parkinson’s Progression Markers Initiative (PPMI)
Funded by: Michael J Fox Foundation
Site Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Kristy Espay 513-558-6517, kristy.sullivan@uc.edu
Natural History and Bio-specimen Repository for Dystonia
Funded by: NIH/NINDS
Site Principal Investigator: Alberto Espay, MD
Study Status: Active, Recruiting
Contact: Jaya Mishra, PhD: 513-558-0169, jaya.mishra@uc.edu
Headache Research
There are no open studies at this time.
Pediatric Neurology Research
UC pediatric neurology research is conducted at Cincinnati Children's Hospital Medical Center. Learn more about current research activities.