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Department of

Molecular Genetics, Biochemistry & Microbiology

Molecular Genetics Track Course Work Descriptions

Molecular and Cellular Biology
26 GNTD 7001
Fall Semester
4 graduate credits
Course Directors: Iain Cartwright, PhD, and Robert Brackenbury, PhD, and William Miller, Ph.D.

Primarily a lecture-based course that represents the first course in the core curriculum series that is designed for all first-year graduate students in the College of Medicine. Topics include DNA replication, recombination and repair; cell cycle regulation; transcriptional regulation; translational regulation; protein trafficking etc.


Biochemistry and Cellular Metabolism
26 GNTD 7002
Spring Semester
3 graduate credits
Course Director: Michael Lieberman, PhD and Paul Rosevear, PhD

Primarily a lecture-based course that represents the second course in the core curriculum series that is designed to be inclusive to all first-year graduate students in the College of Medicine. Topics include protein structure and function; enzyme kinetics and regulation; and metabolism.


Introductory Microbiology 
26 MG 7003
Fall Semester
3 graduate credits
Course Director: Richard Thompson, PhD

This course will provide a foundation in the biology of prokaryotes and viruses. Topics include viral replication and growth, prokaryotic structure and function, bacterial genetics, antibiotics and an introduction to basic immunological principles. Molgen Students should register for 3 credits, while student not needing the introduction to immunological principles should register for 2 credits.


Mechanisms of Signal Transduction
26 MG 7024
Spring Semester
2 graduate credits
Course Director: William Miller, PhD

Provides a research literature-based view of modern aspects of signal transduction and includes student-driven discussions of seminal papers in the signal transduction field. Topics include receptor mediated signal transduction originating at the plasma membrane and cover major effector pathways including those leading to second messenger generation, kinase cascade assembly and activation of transcription factors. Signaling mechanisms related to cellular homeostasis, developmental biology, immunology and cancer will also be discussed.


Immunology
26 MG 7023
Spring Semester
2 graduate credits
Course Director: John Monaco, PhD

A comprehensive introductory level immunology course for graduate students, advanced undergraduates, technicians and fellows. It will cover basic immunochemistry and cellular and molecular immunology.


Advanced Topics in Macromolecular Structure Determination
26 MG 8010
Spring Semester  (even years)
1 graduate credit
Course Directors: Rhett Kovall, PhD and Tom Thompson, PhD

The Advanced Topics in Macromolecular Structure Determination course will discuss contemporary issues regarding macromolecular X-ray crystallography such as new computational techniques and programs, advances in protein expression, purification, crystallization, unique problems regarding phasing, X-ray data collection, model building and interpretation. Students will be required to lead a topic discussion. 


Special Topics in Macromolecular Crystallography
26 MG 8004C
Fall Semester (odd years)
1-3 graduate credits
Course Directors: Rhett Kovall, PhD and Tom Thompson, PhD

The advanced topics course will explore the principles, methodologies and practical applications of macromolecular crystallography in contemporary structural biology research. In addition to understanding the central issues that underlie macromolecular structure determination by crystallographic methods, students will learn through hands-on experiments of the practical aspects for growing crystals, collecting and analyzing X-ray diffraction data, and ultimately determining crystal structures.

Molecular and Cell Biology Text

More Information

For more information on the graduate program, please contact us:

Brenda Cole
Graduate Program Manager

Molecular Genetics, Biochemistry and Microbiology
University of Cincinnati College of Medicine
P.O. Box 670524
231 Albert Sabin Way
Cincinnati, OH 45267-0524 

Phone: 513-558-5510
Email: brenda.cole@uc.edu