Today is Tuesday, Oct. 15, 2019

Department of

Internal Medicine - Biomedical Ultrasonics and Cavitation Laboratory

Publications

For the most up-to-date list, please find our publications via Scopus, ORCIDPubMed, or Google Scholar.

Last updated 6 October 2019

Peer-Reviewed Publications

  1. Patrick H. Kee, Melanie R. Moody, Shao-Ling Huang, Hyunggun Kim, Xing Yin, Tao Peng, Susan T. Laing, Melvin E. Klegerman, Mohammad H. Rahbar, Deborah Vela, Curtis Genstler, Kevin J. Haworth, Christy K. Holland, David D. McPherson. (accepted) “Stabilizing peri- stent restenosis using a novel therapeutic carrier.” JACC: Basic to Translational Science.

  2. Robert Kleven, Himanshu Shekhar, Kunal Karani, Nuria Salido, T. Douglas Mast, Kevin J. Haworth, Christy K. Holland. (2019) “The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro.” Physics in Medicine and Biology. 64(16):165015(1-17) doi: 10.1088/1361-6560/ab293b

  3. Karla P. Mercado-Shekhar, Haili Su, Deepak S. Kalaikadal, John N. Lorenz, Raj M. Manglik, Christy K. Holland, Andrew N. Redington, Kevin J. Haworth. (2019) “Acoustic droplet vaporization-mediated dissolved oxygen scavenging in blood-mimicking fluids, plasma, and blood.” Ultrasonics Sonochemistry. 56:114-124 doi: 10.1016/j.ultsonch.2019.03.029

  4. Himanshu Shekhar, Pala Arunkumar, Tao Peng, Melanie R. Moody, Kevin J. Haworth, Shaoling Huang, David D. McPherson, Christy K. Holland. (2019) “Lipid-shelled microbubbles for ultrasound-triggered release of xenon.” Neurotherapeutics. doi: 10.1007/s13311-019-00733-4

  5. Khoi Nguyen, Hsuan-Yeh Pan, Kevin J. Haworth, Eric Mahoney, Karla P. Mercado-Shekhar, Chia-Ying Lin, Zhe Zhang, Yoonjee Park. (2019) “Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a Potential Degenerative Disc Disease Treatment.” Ultrasound in Medicine and Biology. 45(1):160-169 doi: 10.1016/j.ultrasmedbio.2018.09.014

  6. Karla P. Mercado-Shekhar, Robert Kleven, Hermes Aponte Rivera, Ryden Lewis, Kunal B. Karani, Hendrick J. Vos, Todd A. Abruzzo, Kevin J. Haworth, Christy K. Holland. (2018) “The Effect of Clot Stiffness on rt-PA Lytic Susceptibility In Vitro.” Ultrasound in Medicine and Biology. 44(12):2710-2727 doi: 10.1016/j.ultrasmedbio.2018.08.005 

  7. Kenneth B. Bader, Kevin J. Haworth, Adam D. Maxwell, and Christy K. Holland. (2018). Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-induced Liq- uefaction In Vitro. IEEE Medical Imaging. 37(1):106-115 doi: 10.1109/TMI.2017.2735238

  8. Kevin J. Haworth, Kenneth B. Bader, Kyle T. Rich, Christy K. Holland, T. Douglas Mast. (2017). Quantitative Frequency-Domain Passive Cavitation Imaging. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 64(1):177-191 doi: 10.1109/TUFFC.2016.2620492

  9. Mark J. Schulz, Guangfeng Hou, Vianessa Ng, Massoud Rabiee, Marc Cahay, Sumeet Chaud- hary, Dustin Lindley, Devika Chauhan, Michael Paine, Dineshwaran Vijayakumar, Chenhao Xu, Zhangzhang Yin, Kevin J. Haworth, Yijun Liu, Murali Sundaram, Weifeng Li, David Mast, Vesselin N. Shanov. (2017). Science to commercialization of carbon nanotube sheet and yarn. WSEAS Transactions on Applied and Theoretical Mechanics. 12:41-50.

  10. Jonathan T. Sutton, Kevin J. Haworth, Shiva Kumar Shanmukhappa, Melanie R. Moody, Melvin R. Klegerman, Joseph K. Griffin, Daniella M. Patton, David D. McPherson, Christy K. Holland. (2016). Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug Delivery. 23(9):3594-3605 doi: 10.1080/10717544.2016.1212441

  11. Kenneth B. Bader, Kevin J. Haworth, Himanshu Shekhar, Adam Maxwell, Tao Peng, David D. McPherson, Christy K. Holland. (2016). Efficacy of histotripsy combined with rt-PA in vitro. Physics in Medicine and Biology. 61(14):5253-5274 doi: 10.1088/0031-9155/61/14/5253

  12. Karla P. Mercado, Kirthi Radhakrishnan, Kyle Stewart, Lindsay Snider, Devin Ryan, Kevin J. Haworth. (2016). Empirical model for size isolating ultrasound-triggered phase-shift emulsions using differential centrifugation. Journal of the Acoustical Society of America - Express Letters. 135(5):EL142-148 doi: 10.1121/1.4946831

  13. Kirthi Radhakrishnan, Christy K. Holland, Kevin J. Haworth. (2016). Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics Sonochemistry. 31:394-403 doi: 10.1016/j.ultsonch.2016.01.019

  14. Kevin J. Haworth, Jason L. Raymond, Kirthi Radhakrishnan, Melanie R. Moody, Shaoling Huang, Tao Peng, Himanshu Shekhar, Melvin E. Klegerman, Hyunggun Kim, David D. McPherson, and Christy K. Holland. (2016). Trans-stent B-mode ultrasound and passive cav- itation imaging. Ultrasound in Medicine and Biology. 42(2):518-527 doi: 10.1016/j.ultrasmedbio.2015.08.014

  15. Melvin E. Klegerman, Ali K. Naji, Kevin J. Haworth, Yuejiao Zou, Eva Golunski, Tao Peng, George L. Britton, Shao-Ling Huang, Christy K. Holland, David D. McPherson. (2016). Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of Liposome Research. 26(1):47-56 doi: 10.3109/08982104.2015.1029494

  16. Kevin J. Haworth, Vasant A. Salgaonkar, Nicholas M. Corregan, Christy K. Holland, T. Douglas Mast. (2015). Using passive cavitation images to classify high-intensity focused ultrasound lesions. Ultrasound in Medicine and Biology. 41(9):2420-2434 doi: 10.1016/j.ultrasmedbio.2015.04.025

  17. Kevin J. Haworth, Christopher R. Weidner, Todd A. Abruzzo, Jason T. Shearn, Christy K. Holland. (2015). Mechanical properties and fibrin characteristics of endovascular coil- clot complexes: Relevance to endovascular cerebral aneurysm repair paradigms. Journal of NeuroInterventional Surgery. 7(4):291-296 doi: 10.1136/neurintsurg-2013-011076

  18. Kirthi Radhakrishnan, Kevin J. Haworth, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2015). Loss of echogenicity and onset of cavitation from echogenic liposomes: Pulse repetition frequency independence. Ultrasound in Medicine and Biology. 41(1):208-221 doi: 10.1016/j.ultrasmedbio.2014.08.021

  19. Jason L. Raymond, Kevin J. Haworth, Kenneth B. Bader, Kirthi Radhakrishnan, Joseph K. Griffin, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2014). Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in Medicine and Biology. 40(2):410-421 doi: 10.1016/j.ultrasmedbio.2013.09.018

  20. Kirthi Radhakrishnan, Kenneth B. Bader, Kevin J. Haworth, Jonathan A. Kopechek, Jason L. Raymond, Bin Huang, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2013). Relationship between cavitation and loss of echogenicity from ultrasound contrast agents.Physics in Medicine and Biology. 58(18):6541-6563 doi: 10.1088/0031-9155/58/18/6541

  21. Sheryl E. Koch, Kevin J. Haworth, Nathan Robbins, Margaret A. Smith, Navneet Lather, Ahmad Anjak, Min Jiang, Priyanka Varma, W. Keith Jones, and Jack Rubinstein. (2013). Age and gender related changes in myocardial function in wild type FVB/N mice as evaluated by conventional and vector velocity echocardiography imaging. Ultrasound in Medicine and Biology. 39(11):2034-2043 doi: 10.1016/j.ultrasmedbio.2013.04.002

  22. Jonathan T. Sutton, Kevin J. Haworth, Gail J. Pyne-Geithman, Christy K. Holland. (2013). Ultrasound-mediated drug delivery for cardiovascular disease. Expert Opinions on Drug De- livery. 10(5):573-592 doi: 10.1517/17425247.2013.772578

  23. Jonathan A. Kopechek, Kevin J. Haworth, Kirthi Radhakrishnan, Shao-Ling Huang, Melvin E. Klegerman, David D. McPherson, Christy K. Holland. (2013). The impact of microbub- bles on measurement of drug release from echogenic liposomes. UItrasonics Sonochemistry. 20(4):1121-1130 doi: 10.1016/j.ultsonch.2012.12.005

  24. Robert Littleton, Kevin J. Haworth, Hong Tang, Kenneth Setchell, Sandra Nelson, Jay Hove. (2013). Automated in vivo platform for the discovery of functional food treatments of hypercholesterolemia in zebrafish. PLoS ONE. 8(1):e52409 1-9 doi: 10.1371/journal.pone.0052409

  25. Kirthi Radhakrishnan, Kevin J. Haworth, Shao-Ling Huang, Melvin E. Klegerman, David D. McPherson, Christy K. Holland. (2012). Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in Medicine and Biology. 38(11):1970-1981 doi: 10.1016/j.ultrasmedbio.2012.06.012

  26. Kevin J. Haworth, T. Douglas Mast, Kirthi Radhakrishnan, Mark T. Burgess, Jonathan A. Kopechek, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2012). Passive imaging with pulsed ultrasound insonations. Journal of the Acoustical Society of America. 132(1):544-553 doi: 10.1121/1.4728230

  27. Jonathan A. Kopechek, Kevin J. Haworth, Jason L. Raymond, T. Douglas Mast, Stephen R. Perrin Jr., Melvin E. Klegerman, Shao-Ling Huang, Tyrone M. Porter, David D. McPherson, Christy K. Holland. (2011). Acoustic characterization of echogenic liposomes: frequency- dependent attenuation and backscatter. Journal of the Acoustical Society of America. 130(5, Pt. 2):3472-3481 doi: 10.1121/1.3626124

  28. Man Zhang, Mario L. Fabiilli, Kevin J. Haworth, Frederic R. Padilla, Scott D. Swanson, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2011). Acoustic droplet vaporization for enhancement of thermal ablation by high intensity focused ultrasound. Academic Radiology. 18(9):1123-1132 doi: 10.1016/j.acra.2011.04.012

  29. Kathryn E. Hitchcock, Nikolas M. Ivancevich, Kevin J. Haworth, Danielle N. Caudell, Deborah C. Vela, Jonathan T. Sutton, Gail J. Pyne-Geithman, Christy K. Holland. (2011). Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultra- sound in Medicine and Biology. 37(8):1240-1251, doi: 10.1016/j.ultrasmedbio.2011.05.011

  30. Man Zhang, Mario L. Fabiilli, Kevin J. Haworth, J. Brian Fowlkes, Oliver D. Kripfgans, William W. Roberts, Kimberly A. Ives, Paul L. Carson. (2010). Initial investigation of acoustic droplet vaporization for occlusion in canine kidney. Ultrasound in Medicine and Biology. 36(10):1691-1703, doi: 10.1016/j.ultrasmedbio.2010.06.020

  31. Mario L. Fabiilli, Kevin J. Haworth, Ian E. Sebastian, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2010). Delivery of chlorambucil using acoustically-triggered, perfluoropen- tane emulsions. Ultrasound in Medicine and Biology. 36(8):1364-1375, doi: 10.1016/j.ultrasmedbio.2010.04.019

  32. Kevin J. Haworth, J. Brian Fowlkes, Paul L. Carson, Oliver D. Kripfgans. (2009). Gen- eralized shot noise model for time-reversal in multiple-scattering media allowing for arbitrary inputs and windowing. Journal of the Acoustical Society of America. 125(5):3129-3140, doi: 10.1121/1.3106133

  33. Mario L. Fabiilli, Kevin J. Haworth, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2009). The role of inertial cavitation in acoustic droplet vaporization. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 56(5):1006-1017, doi: 10.1109/TUFFC.2009.1132

  34. Kevin J. Haworth, J. Brian Fowlkes, Paul L. Carson, Oliver D. Kripfgans. (2008). To- wards aberration correction of transcranial ultrasound using acoustic droplet vaporization.Ultrasound in Medicine and Biology. 34(3):435-445, doi: 10.1016/j.ultrasmedbio.2007.08.004

  35. Kevin J. Haworth, J. Brian Fowlkes, Paul L. Carson, Oliver D. Kripfgans. (2008). To- wards aberration correction of transcranial ultrasound using acoustic droplet vaporization.Ultrasound in Medicine and Biology. 34(3):435-445, doi: 10.1016/j.ultrasmedbio.2007.08.004

Proceedings Articles

  1. Kevin J. Haworth, Bryan H. Goldstein, Karla P. Mercado-Shekhar, Rohan Srivastava, P. Arunkumar, Haili Su, Ellena M. Privitera, Christy K. Holland, Andrew N. Redington. (2017). Dissolved Oxygen Scavenging by Acoustic Droplet Vaporization using Intravascular Ultra- sound. 2017 IEEE International Ultrasonics Symposium Proceedings. 1:1-4 doi: 10.1109/ULT- SYM.2017.8091704
  2.  Kevin J. Haworth, Vasant A. Salgaonkar, Nicholas M. Corregan, Christy K. Holland, T. Douglas Mast. (2013). Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver. Proceedings of Meetings on Acoustics. 19:075022 doi: 10.1121/1.4800327
  3. Kevin J. Haworth, Oliver D. Kripfgans. (2008). Initial Growth of Ultrasonically Vaporized Perfluorocarbon Microdroplets. 2008 IEEE International Ultrasonics Symposium Proceedings. 1:623-626
  4. Kevin J. Haworth, Mario L. Fabiilli, J. Brian Fowlkes, Man Zhang, Oliver D. Kripfgans, William W. Roberts, Paul L. Carson. (2008). Mean Echo Power as a Measure of Flow Reduction for Bubble Occlusion Therapy. 2008 IEEE International Ultrasonics Symposium Proceedings. 1:768-771
  5. Mario L. Fabiilli, Kevin J. Haworth, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2008). The Role of Inertial Cavitation in Acoustic Droplet Vaporization. 2008 IEEE Inter- national Ultrasonics Symposium Proceedings. 1:776-779