Today is Wednesday, Sep. 19, 2018

Department of

Internal Medicine - Biomedical Ultrasonics and Cavitation Laboratory

Dr. Haworth in his lab with students

The Biomedical Ultrasonics and Cavitation Laboratory (BUCL) is directed by Kevin Haworth, PhD and located in the interdisciplinary Cardiovascular Center (Room 3950) at the University of Cincinnati.  BUCL is a member of the Image-guided Ultrasound Therapeutics Laboratories

Our focus is on the development of ultrasound and cavitation for the improvement of human health. We have a particular focus on acoustic droplet vaporization and passive cavitation imaging.  

BUCL is always looking for highly motivated individuals to contribute to our research mission. Please contact us if you are interested in joining us. 


News and Announcements

2018

Frequency-domain Passive Cavitation Imaging Paper Recognized: Our 2017 paper on passive cavitation imaging was recognized as an Editor's Selection Article in April 2018 and August 2018.

Rohan Srivastava and Rachel Benton Present: Rohan Srivastava, a rising senior in the medical sciences undergraduate program and Rachel Benton in the neurobiology undergraduate program successfully presented their summer research projects Summer Capstone Symposium.

Ishan Anand Receives Schwartzman Scholarship:  Ishan Anand was selected as a 2019 Schwartzman Scholar and will pursue a fully-funded graduate degree at Tsinghua University.

Karla Mercado-Shekhar Receives Two Travel Awards to Present at the Acoustical Society of America Meeting: Karla Mercado-Shekhar, PhD received a Young Investigator Travel Grant from the Committee on Women in Acoustics and an Early Career Travel Award from the ASA to present her abstract on "Clot stiffness is inversely correlated with rt-PA thrombolytic efficacy in vitro" at the 175th Meeting of the ASA.

Haili Su Presents at the American Institute of Ultrasound in Medicine: Haili Su, MD, PhD presented her work on oxygen scavenging using ADV at the 2018 American Institute of Ultrasound in Medicine Convention.

Haworth Presents at Fields Institute: Kevin J. Haworth, PhD provided an invited lecture on passive cavitation imaging at the Fields Institute for Research in Mathematical Sciences for a workshop on High Intensity Focused Ultrasound: Mathematical Modeling and Clinical Applications.

Haworth Re-elected to American Institute of Ultrasound in Medicine Bioeffects Committee: Kevin J. Haworth, PhD was re-elected to the AIUM Bioeffects Committee to serve a three year term from 2018-2021.

2017

Karla Mercado-Shekhar Receives Early Career Travel Award: Karla P. Mercado-Shekhar was awarded a travel award by the Acoustical Society of America to support the presentation of her work on the effect of fluid parameters on ADV at the Acoustics '17 meeting.

Holland and Haworth Awarded Subcontract to Study Ultrasound-Mediated Drug Delivery: Continuing on a long-standing collaboration, Christy K. Holland, PhD and Kevin J. Haworth, PhD will be working with David D. McPherson, MD at the University of Texas Health Science Center at Houston and EKOS Corp. to establish an ultrasound-mediated drug delivery system using echogenic liposomes and an EkoSonic(R) ultrasound system for reducing neointimal hyperplasia following arterial stent deployments. The five year project will culminate with first-in-human trials.

Holland and Haworth Awarded Subcontract to Study Histotripsy: Kenneth B. Bader, PhD was awarded an NIH R01 to study histotripsy as a treatment for deep vein thrombosis.  This grant builds on the results obtained at the University of Cincinnati from a Focused Ultrasound Foundation grant.  Christy K. Holland, PhD and Kevin J. Haworth, PhD will lead supporting work in Cincinnati on pre-clinical studies and image-guidance of the therapy.

Haworth Co-Chairs Session at 2017 AIUM Convention: Kevin J. Haworth, PhD and Meaghan O'Reilly, PhD  co-chaired a special interest session on Monitoring at the 2017 AIUM Convention.

2016

Austin Wanek Receives Robert W. Young Award:  Austin Wanek received a Robert W. Young Award for Undergraduate Student Research in Acoustics from the Acoustical Society of America.

Kevin Haworth Awarded NIH K25 Mentored Quantiative Research Development Grant: Kevin J. Haworth, PhD, has received a four year NIH K25 Mentored Quantitative Research Development Award to investigate oxygen scavenging in myocardial  reperfusion injury.

Karla Mercado Awarded NIH Diversity Supplement:  Karla Mercado, PhD has received a 2 year award to study clot stiffness with ultrasound and its relationship to lytic susceptibility. This research will support Christy K. Holland's NIH-NINDS R01 on ultrasound assisted thrombolysis for stroke therapy.

Vincent Huang Wins First Place in the UC SURF Poster Competition:  Vincent Huang's summer research on the safety of acoustic droplet vaporization won one of two first place awards, out of over 200 posters, at the Summer Undergraduate Research Fellowship Poster Symposium.

Haworth Elected as President Elect of UC Chapter of Sigma Xi: Kevin J. Haworth, PhD was elected to serve as the Vice President and President-Elect of the UC Chapter of Sigma Xi for the 2016-2017 academic year.  Haworth will serve as President of the chapter during the 2017-2018 academic year.

Research Update, Histotripsy Standards and Lysis of Deep Vein Thrombosis: With the eventual goal to use focused ultrasound to dissolve chronic deep vein blood thrombi, Kenneth B. Bader, PhD and colleagues at the University of Cincinnati recently completed a study to develop standards to regulate microbubble cloud formation during histotripsy pulses.

2015

Haworth Awarded AHA Scientist Development Grant:  Kevin J. Haworth, PhD, has received a four year American Heart Association Award to investigate ultrasound-mediated oxygen scavenging to inhibit reperfusion injury.

Bader and Haworth Co-Chair Scientific Session at ASA: Kenneth B. Bader, PhD and Kevin J. Haworth, PhD co-chaired a scientific session on ultrasound-enhanced thrombolysis at the 170th meeting of the Acoustical Society of America.

Haworth Elected to American Institute of Ultrasound in Medicine Bioeffects Committee: Kevin J. Haworth, PhD was elected as a member of the AIUM Bioeffects Committee to serve a three year term from 2015-2018.

2014

Kenneth Bader receives Focused Ultrasound Foundation Award: The Focused Ultrasound Foundation awarded Kenneth B. Bader, PhD a grant to study histotripsy in collaboration with the FDA.  BUCL will provide expertise in passive cavitation imaging.

Haworth and Kripfgans Co-Chair Scientific Session at ASA: Kevin J. Haworth, PhD and Oliver D. Kripfgans, PhD co-chaired a scientific session on cavitation monitoring at the 168th meeting of the Acoustical Society of America.

2013

Haworth Receives Conference Attendance Grant:  The abstract provided by Kevin J. Haworth, PhD and colleagues for presentation at the Joint Meeting of the 21st International Congress on Acoustics and the Acoustical Society of America was selected for an ICA Young Scientist Award to support Dr. Haworth's presentation at the meeting.

Haworth Awarded NIH-CTSA KL2 Grant: Kevin J. Haworth, PhD received a 2 year NIH-CTSA KL2 award to investigate the potential of acoustic droplet vaporization as a therapy for ischemic stroke.

2012

Image-guided Ultrasound Therapeutics Lab to Present Research: Members of the Image-guided Ultrasound Therapeutics Laboratories travel to Kansas City, Missouri to present their research.  In all, 8 presentations were made from IgUTL at the 164th meeting of the Acoustical Society of America.