Today is Wednesday, Feb. 19, 2020

Department of Internal Medicine

Immunology, Allergy and Rheumatology

Photo of  William Ridgway, MD

William Ridgway, MD

Professor of Medicine, Division Director

Clinical Interest

Internal Medicine


Internal Medicine

  • Bachelor's Degree: Haverford College
  • Post-baccalaureate: Bryn Mawr College
  • Medical Degree: University of Rochester
  • Residency : Stanford University Hospital
  • Clinical Fellowship: Stanford University Hospital
  • Physician Postdoctoral Fellowship : Howard Hughes Medical Institute
  • Research Fellowship: Stanford University School of Medicine
  • Research Associate : Stanford University School of Medicine
Board Certifications & Licenses
  • American Board of Internal Medicine 09/22/1993
  • American Board of Internal Medicine (Rheumatology) 10/23/2008
Contact Information
  • Health Professions Building
  • 3255 Eden Ave
  • Suite 350
  • Cincinnati, Ohio 45267-0563
  • Office 513-558-4701
  • Fax 513-558-3799
  • Email

Peer Reviewed Publications

Forsberg, Matthew H; Ciecko, Ashley E; Bednar, Kyle J; Itoh, Arata; Kachapati, Kritika; Ridgway, William M; Chen, Yi-Guang 2017. CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. Journal of immunology (Baltimore, Md. : 1950), 198 10, 3857-3868

Itoh, Arata; Ridgway, William M 2017. Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes. ImmunoTargets and therapy, 6 , 31-38

Ma, Hong-Di; Ma, Wen-Tao; Liu, Qing-Zhi; Zhao, Zhi-Bin; Liu, Mu-Zi-Ying; Tsuneyama, Koichi; Gao, Jin-Ming; Ridgway, William M; Ansari, Aftab A; Gershwin, M Eric; Fei, Yun-Yun; Lian, Zhe-Xiong 2017. Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8(+) T cell activation. Journal of autoimmunity, 78 , 19-28

Yang, G-X; Sun, Y; Tsuneyama, K; Zhang, W; Leung, P S C; He, X-S; Ansari, A A; Bowlus, C; Ridgway, W M; Gershwin, M E 2016. Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice. Clinical and experimental immunology, 185 2, 154-64

Yang, Jing-Bo; Wang, Yin-Hu; Yang, Wei; Lu, Fang-Ting; Ma, Hong-Di; Zhao, Zhi-Bin; Jia, Yan-Jie; Tang, Wei; Tsuneyama, Koichi; Ridgway, William M; Gershwin, M Eric; Lian, Zhe-Xiong 2016. Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy. Journal of autoimmunity, 66 , 108-17

Bednar, Kyle J; Tsukamoto, Hiroki; Kachapati, Kritika; Ohta, Shoichiro; Wu, Yuehong; Katz, Jonathan D; Ascherman, Dana P; Ridgway, William M 2015. Reversal of New-Onset Type 1 Diabetes with an agonistic TLR4/MD-2 Monoclonal Antibody. Diabetes, ,

Wang, Yin-Hu; Yang, Wei; Yang, Jing-Bo; Jia, Yan-Jie; Tang, Wei; Gershwin, M Eric; Ridgway, William M; Lian, Zhe-Xiong 2015. Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis. Journal of autoimmunity, 59 , 26-37

Bednar, Kyle J; Ridgway, William M 2014. Targeting innate immunity for treatment of type 1 diabetes. Immunotherapy, 6 12, 1239-42

Huang, Wenting; Kachapati, Kritika; Adams, David; Wu, Yuehong; Leung, Patrick S C; Yang, Guo-Xiang; Zhang, Weici; Ansari, Aftab A; Flavell, Richard A; Gershwin, M Eric; Ridgway, William M 2014. Murine autoimmune cholangitis requires two hits: Cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. Journal of autoimmunity, ,

Ridgway, William M 2014. A new tool for dissecting genetic control of type 1 diabetes. Diabetes, 63 1, 56-8

Ridgway, William M; Gershwin, M Eric 2014. Prometheus unbound: NKT cells inhibit hepatic regeneration. Hepatology (Baltimore, Md.), 60 4, 1133-5

Wang, Jinjun; Yang, Guo-Xiang; Tsuneyama, Koichi; Gershwin, M Eric; Ridgway, William M; Leung, Patrick S C 2014. Animal models of primary biliary cirrhosis. Seminars in liver disease, 34 3, 285-96

Yang, Wei; Yao, Yuan; Yang, Yan-Qing; Lu, Fang-Ting; Li, Liang; Wang, Yin-Hu; Nakajima, Takahiko; Tsuneyama, Koichi; Ridgway, William M; Gershwin, M Eric; Lian, Zhe-Xiong 2014. Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2R? deleted mice. PloS one, 9 8, e105351

Kachapati, Kritika; Bednar, Kyle J; Adams, David E; Wu, Yuehong; Mittler, Robert S; Jordan, Michael B; Hinerman, Jennifer M; Herr, Andrew B; Ridgway, William M 2013. Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice. Journal of autoimmunity, 47 , 94-103

Kachapati, Kritika; Adams, David E; Wu, Yuehong; Steward, Charles A; Rainbow, Daniel B; Wicker, Linda S; Mittler, Robert S; Ridgway, William M 2012. The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. Journal of immunology (Baltimore, Md. : 1950), 189 10, 5001-15

Kachapati, Kritika; Adams, David; Bednar, Kyle; Ridgway, William M 2012. The non-obese diabetic (NOD) mouse as a model of human type 1 diabetes. Methods in molecular biology (Clifton, N.J.), 933 , 3-16

Mohammed, Javid P; Fusakio, Michael E; Rainbow, Daniel B; Moule, Carolyn; Fraser, Heather I; Clark, Jan; Todd, John A; Peterson, Laurence B; Savage, Paul B; Wills-Karp, Marsha; Ridgway, William M; Wicker, Linda S; Mattner, Jochen 2011. Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity. Journal of immunology (Baltimore, Md. : 1950), 187 1, 337-49