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Photo of  Joseph E. Palascak, MD

Joseph E. Palascak, MD

Education/Credentials
  • Fellowship : Thomas Jefferson University (Hematologic Research )
  • Residency: Thomas Jefferson University Hospital (Internal Medicine)
  • Medical Degree: Thomas Jefferson University, Jefferson Medical College
  • Bachelor's Degree: Duquesne University (Chemistry)
Board Certifications & Licenses

American Board of Internal Medicine (Hematology) (Certification Date: 1978-06-27)
American Board of Internal Medicine (Certification Date: 1975-06-18)

Contact Information
Research Interests

Hemophilia, Sickle Cell Disease, Hematology Oncology

Clinical Interests

Hematology

Anemia

Erythrocytosis

Hemochromotosis

Hemolysis

High platlet count

High red blood cells

Hypgammaglobulinemia

Immunodeficiency

Leuckopenia

Leukocytosis

Low platlet count

Low red blood cells

Lymphadenopathy

Neutropenia

Pancytopenia

Polycythemia vera

Thalassemia

Thrombocytopenia

Peer Reviewed Publications

Agne, J L; Ahmad, N; Palascak, J E; Khaled, R; Karim, N A 2015. VWD type 2N (Normandy) in two sisters. Haemophilia : the official journal of the World Federation of Hemophilia, 21 3, e223-5

Beg,M.S.; Komrokji,R.S.; Ahmed,K.; Safa,M.M. 2008. Oxaliplatin-induced immune mediated thrombocytopenia Cancer Chemotherapy and Pharmacology, , 1

Atiq,M.; Safa,M. 2007. Recurrent hypoglycemia associated with poorly differentiated carcinoma of the liver American Journal of Clinical Oncology: Cancer Clinical Trials, 30 2, 213

Jazieh,A.R.; Younas,A.; Safa,M.; Redmond,K.; Buncher,R.; Howington,J. 2007. Phase i clinical trial of concurrent paclitaxel, carboplatin, and external beam chest irradiation with glutamine in patients with locally advanced non-small cell lung cancer Cancer Investigation, 25 5, 294

Nahleh,Z.A.; Srikantiah,R.; Safa,M.; Jazieh,A.-R.; Muhleman,A.; Komrokji,R. 2007. Male breast cancer in the veterans affairs population: a comparative analysis Cancer, 109 8, 1471

Lowy,A.M.; Firdaus,I.; Roychowdhury,D.; Redmond,K.; Howington,J.A.; Sussman,J.J.; Safa,M.; Ahmad,S.A.; Reed,M.F.; Rose,P.; James,L.; Jazieh,A.R. 2006. A phase ii study of sequential neoadjuvant gemcitabine and paclitaxel, radiation therapy with cisplatin and 5-fluorouracil and surgery in locally advanced esophageal carcinoma American Journal of Clinical Oncology: Cancer Clinical Trials, 29 6, 555

Safa,M.; Jazieh,A.-R. 2006. Lack of a uniform approach to clinical research training for hematology oncology fellows Journal of Cancer Education, 21 3, 166

Goedert,J.J.; Siegel,J.; Miller,K.; Lederman,M.M.; Thompson,A.; Browning,B.; Gamerman,S.; McRedmond,K.; Withycombe,J.; Gruppo,R.; Stack,G.; Lusher,J.; Percy,L. 2005. Prevalence of conditions associated with human immunodeficiency and hepatits virus infections among persons with haemophilia, 2001-2003 Haemophilia, 11 5, 516

Parameswaran,R.; Shapiro,A.D.; Gill,J.C.; Kessler,C.M.; Abshire,T.; Angiolillo,A.; Boggio,L.; Cohen,A.; DiMichele,D.; Hanna,W.; Hoots,K.; Hord,J.; Key,N.; Konkle,B.; Kouides,P.; Kurczynski,E.; Marks,P.; Palascak,J.; Pipe,S.; Ragni,M.; Rivard,G.; Shopnick,R.; Tarantino,M.; Valentino,L.; Watts,R.; White,G. 2005. Dose effect and efficacy of rfviia in the treatment of haemophilia patients with inhibitors: analysis from the hemophilia and thrombosis research society registry Haemophilia, 11 2, 100

Thompson,A.R.; Gill,J.C.; Ewenstein,B.M.; Mueller-Velten,G.; Schwartz,B.A.; Abshire,T.; Ambinder,R.; Angiolillo,A.; Arkel,Y.; Beardsley,D.; Benjamin,R. 2004. Successful treatment for patients with von willebrand disease undergoing urgent surgery using factor viii/vwf concentrate (humate-p®) Haemophilia, 10 1, 42

Gill,J.C.; Ewenstein,B.M.; Thompson,A.R.; Mueller-Velten,G.; Schwartz,B.A.; Abshire,T.; Ambinder,R.; Angiolillo,A.; Arkel,Y.; Beardsley,D.; Benjamin,R.; Binder,M.; Charbel,F.; Cooper,B.; Cornell,N.; Czapek,E.; Eisenberg,P.; Ewenstein,B.; Garcia-Ortiz,S.; Gastineau,D.; Gill,J.; Heggie,G.; Heisel,M.; Joist,H.; Knupp,C.; Lewis,B.; Matthews,D.; McKenna,P.; Murukutla,S.; Palascak,J.; Penner,J.; Powell,J.; Ritter,H.; Francisco,R.; Shapiro,A.; Simpson,T.; Stanek,M.; Thompson,A.R.; Tongol,J.; Waterbury,L.; White,G.; Young,R. 2003. Successful treatment of urgent bleeding in von willebrand disease with factor viii/vwf concentrate (humate-p®): use of the ristocetin cofactor assay (vwf:rco) to measure potency and to guide therapy Haemophilia, 9 6, 688

Safa,M.; Lower,E.E.; Hasselgren,P.O.; Hungness,E.S.; Gazder,P.; Aron,B.; Shaughnessy,E.A.; Yassin,R. 2002. Bilateral synchronous breast cancer and her-2/neu overexpression Breast Cancer Research and Treatment, 72 3, 195

Hickman, M A; Bernstein, I L; Palascak, J E 2000. Successful administration of iron dextran in a patient who experienced a life threatening reaction to intravenous iron dextran. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 84 2, 262-3

Hickman,M.A.; Bernstein,I.L.; Palascak,J.E. 2000. Successful administration of iron dextran in a patient who experienced a life threatening reaction to intravenous iron dextran Annals of Allergy, Asthma and Immunology, 84 2, 262

Hungness,E.S.; Safa,M.; Shaughnessy,E.A.; Aron,B.S.; Gazder,P.A.; Hawkins,H.H.; Lower,E.E.; Seeskin,C.; Yassin,R.S.; Hasselgren,P.-O. 2000. Bilateral synchronous breast cancer: mode of detection and comparison of histologic features between the 2 breasts Surgery, 128 4, 702

Yasin,Z.; Retzinger,G.; Palascak,J. 2000. Thrombosis refractory to urokinase in a patient with pnh and factor v leiden mutation. is there a role for plasmaphersis? Blood, 98 11 PART II,

Yasin,Z.; Quick,D.; Thiagarajan,P.; Spoor,D.; Caraveo,J.; Palascak,J. 1999. Light-chain paraproteins with lupus anticoagulant activity American Journal of Hematology, 62 2, 99

Erslev, A J; Palascak, J E; Shaikh, B S; Martinez, J 1998. Platelet kinetics in autosomal dominant macrothrombocytopenia. The Journal of laboratory and clinical medicine, 131 6, 488-95; discussion 4

Erslev,A.J.; Palascak,J.E.; Shaikh,B.S.; Martinez,J. 1998. Platelet kinetics in autosomal dominant macrothrombocytopenia Journal of Laboratory and Clinical Medicine, 131 6, 488

Franco,R.; Barker-Gear,R.; Silberstein,E.; Mayfield,G.; Weiner,M.; Palascak,J.; Green,R. 1992. Sickle cells modified by an osmotic pulse in the presence of inositol hexaphosphate have decreased intracellular hemoglobin concentration and decreased in vitro sickling without prolonged in vivo survival Advances in Experimental Medicine and Biology, 326 , 325

Cotto,M.A.; Lutomski,D.M.; Palascak,J.E.; Fant,W.K.; LaFrance,R.J. 1990. Fat emulsion effects on prothrombin time in warfarin anticoagulated patients: an in vitro study Journal of Parenteral and Enteral Nutrition, 14 2, 201

Martelo, O J; Palascak, J E 1988. Platelet dysfunction and bleeding associated with beta-lactam antibiotics. The Journal of infectious diseases, 157 5, 1100-1

Martelo,O.J.; Palascak,J.E. 1988. Platelet dysfunction and bleeding associated with beta-lactam antibiotics. Journal of Infectious Diseases, 157 5, 1100

Lutomski,D.M.; Palascak,J.E.; Bower,R.H. 1987. Warfarin resistance associated with intravenous lipid administration Journal of Parenteral and Enteral Nutrition, 11 3, 316

Miller, M A; Palascak, J E; Thompson, M R; Martelo, O J 1985. A modified SDS agarose gel method for determining factor VIII von Willebrand factor multimers using commercially available reagents. Thrombosis research, 39 6, 777-80

Miller,M.A.; Palascak,J.E.; Thompson,M.R. 1985. A modified sds agarose gel method for determining factor viii von willebrand factor multimers using commercially available reagents Thrombosis Research, 39 6, 777

Martinez, J; Keane, P M; Gilman, P B; Palascak, J E 1983. The abnormal carbohydrate composition of the dysfibrinogenemia associated with liver disease. Annals of the New York Academy of Sciences, 408 , 388-96

Martinez, J; MacDonald, K A; Palascak, J E 1983. The role of sialic acid in the dysfibrinogenemia associated with liver disease: distribution of sialic acid on the constituent chains. Blood, 61 6, 1196-202

Martinez,J.; Keane,P.M.; Gilman,P.B.; Palascak,J.E. 1983. The abnormal carbohydrate composition of the dysfibrinogenemia associated with liver disease Annals of the New York Academy of Sciences, Vol. 408 , 388

Martinez,J.; MacDonald,K.A.; Palascak,J.E. 1983. The role of sialic acid in the dysfibrinogenemia associated with liver disease: distribution of sialic acid on the constituent chains Blood, 61 6, 1196

Lusher, J M; Shapiro, S S; Palascak, J E; Rao, A V; Levine, P H; Blatt, P M 1980. Efficacy of prothrombin-complex concentrates in hemophiliacs with antibodies to factor VIII: a multicenter therapeutic trial. The New England journal of medicine, 303 8, 421-5

Lusher, J M; Shapiro, S S; Palascak, J E; Rao, A V; Levine, P H; Blatt, P M 1980. Prothrombin complex concentrates in hemophiliacs with inhibitors--a multicenter therapeutic trial. Transactions of the Association of American Physicians, 93 , 175-81

Lusher,J.M.; Shapiro,S.S.; Palascak,J.E. 1980. Efficacy of prothrombin-complex concentrates in hemophiliacs with antibodies to factor viii. a multicenter therapeutic trial New England Journal of Medicine, 303 8, 421

Lusher,J.M.; Shapiro,S.S.; Palascak,J.E.; Rao,A.V.; Levine,P.H.; Blatt,P.M. 1980. Prothrombin complex concentrates in hemophiliacs with inhibitors--a multicenter therapeutic trial. Transactions of the Association of American Physicians, 93 , 175

Martinez, J; Palascak, J E; Kwasniak, D 1978. Abnormal sialic acid content of the dysfibrinogenemia associated with liver disease. The Journal of clinical investigation, 61 2, 535-8

Martinez,J.; Palascak,J.E.; Kwasniak,D. 1978. Abnormal sialic acid content of the dysfibrinogenemia associated with liver disease Journal of Clinical Investigation, 61 2, 535

Martinez,J.; Palascak,J.; Peters,C. 1977. Functional and metabolic properties of human asialofibrinogen Journal of Laboratory and Clinical Medicine, 89 2, 367

Palascak, J E; Martinez, J 1977. Dysfibrinogenemia associated with liver disease. The Journal of clinical investigation, 60 1, 89-95

Palascak, J E; Shapiro, S R 1977. Anti-factor VIII anamnesis after factor IX complex. The New England journal of medicine, 297 25, 1403

Palascak,J.E.; Martinez,J. 1977. Dysfibrinogenemia associated with liver disease Journal of Clinical Investigation, 60 1, 89

Palascak,J.E.; Shapiro,S.R. 1977. Anti-factor viii anamnesis after factor ix complex. New England Journal of Medicine, 297 25, 1403

Martinez, J; Palascak, J E; Peters, C L 1975. Proceedings: Functional and metabolic studies of human asialofibrinogen. Thrombosis et diathesis haemorrhagica, 34 1, 324

Martinez,J.; Palascak,J.E.; Peters,C.L. 1975. Proceedings: functional and metabolic studies of human asialofibrinogen. Thrombosis et diathesis haemorrhagica, 34 1, 324

Krauss J.S.;Lusher J.M.;Shapiro S.S.;Palascak J.E.;Levine P.H.;Blatt P.M. 12-11-1980. Treatment of Hemophilia with Prothrombincomplex Concentrates New England Journal of Medicine, 303 24, 1418

Franco R.;Barker-Gear R.;Silberstein E.;Mayfield G.;Weiner M.;Palascak J.;Green R. 12-01-1992. Sickle cells modified by an osmotic pulse in the presence of inositol hexaphosphate have decreased i Advances in Experimental Medicine and Biology, 326 , 325-331

Yasin Z.;Quick D.;Thiagarajan P.;Spoor D.;Caraveo J.;Palascak J. 10-13-1999. Light-chain paraproteins with lupus anticoagulant activity American Journal of Hematology, 62 2, 99-102

Goedert J.J.;Siegel J.;Miller K.;Lederman M.M.;Thompson A.;Browning B.;Gamerman S.;McRedmond K.;Withycombe J.;Gruppo R.;Stack G.;Lusher J.;Percy L.;Nugent D.;McDaniel M.;Manno C.;Butler R.;Wade A.;Angiolillo A.;Luban N.L.C.;Guelcher C.;Tarantino M.;Greer S.;Gill J.;Nelson J.;White G.;Fried M.;Grimsley A.L.;DiMichele D.;Goldberg I.;French J.;Hibner S.;Steinberg J.;Faust S.;Key N.;Hannemann V.;Kessler C.M.;Lee A.E.;Eyster M.E.;Galli K.;Jenkins G.;Bernstein Z.P.;Belling L.;Shapiro A.;Halley M.;Noblet P.;Jardine L.;Laudenbach L.;Lipton R.;Pece C.;Leissinger C.A.;Schmidt C.;Carr M.;Nolte M.;Manco-Johnson M.;Giambartolomei S.;Rubin S.H.;Belliveau D.;Aledort L.;McCarthy J.;Lemons R.;Bleak S.;Kraut E.;Witkoff L.;Sexauer C.;Kiplinger F.;Thompson A.;Cooper C.;Britton H.;Cobb K.;Reimers H.J.;Bagato J.A.;Powell J.S.;Herr M.;Scott K.;Hutter J.;Damiano M.L.;Navarro W.;Roth J.;Palascak J.;Sherman K.;Heffner M.;DiPaolo J.;Lammer M.;Iyer R.;Matthew P.;Schwartz M.;Konkle B.;Vijayanathan N.;Dugdale M.;Lilley D.;Hoots K.;Brown D.;Ullman M.;Neff A.;Klintworth S.;Sabio H.;Smith A.;Karafoulidou A. 09-01-2005. Prevalence of conditions associated with human immunodeficiency and hepatits virus infections among Haemophilia, 11 5, 516-528

Lusher J.M.;Shapiro S.S.;Palascak J.E.;Rao A.V.;Levine P.H.;Blatt P.M. 08-21-1980. Efficacy of Prothrombin-Complex Concentrates in Hemophiliacs with Antibodies to Factor VIII: A Multi New England Journal of Medicine, 303 8, 421-425

Manco-Johnson M.J.;Bomgaars L.;Palascak J.;Shapiro A.;Geil J.;Fritsch S.;Pavlova B.G.;Gelmont D. 07-01-2016. Efficacy and safety of protein C concentrate to treat purpura fulminans and thromboembolic events in Thrombosis and Haemostasis, 116 1, 58-68

Sherman K.E.;Ke R.;Rouster S.D.;Abdel-Hameed E.A.;Park C.;Palascak J.;Perelson A.S. 07-01-2016. Viral dynamic modelling of Hepatitis C and resistance-associated variants in haemophiliacs Haemophilia, 22 4, 543-548

Tsuang W.;Navaneethan U.;Ruiz L.;Palascak J.B.;Gelrud A. 04-01-2009. Hypertriglyceridemic pancreatitis: Presentation and management American Journal of Gastroenterology, 104 4, 984-991

Abildgaard C.F.;Lusher J.M.;Shapiro S.S.;Palascak J.E.;Levine P.H.;Blatt P.M. 03-12-1981. Hazards of Prothrombin-Complex Concentrates in Treatment of Hemophilia New England Journal of Medicine, 304 11, 670-671

Parameswaran R.;Shapiro A.;Gill J.;Kessler C.;Abshire T.;Angiolillo A.;Boggio L.;Cohen A.;DiMichele D.;Hanna W.;Hoots K.;Hord J.;Key N.;Konkle B.;Kouides P.;Kurczynski E.;Marks P.;Palascak J.;Pipe S.;Ragni M.;Rivard G.;Shopnick R.;Tarantino M.;Valentino L.;Watts R.;White G. 03-01-2005. Dose effect and efficacy of rFVIIa in the treatment of haemophilia patients with inhibitors: Analysi Haemophilia, 11 2, 100-106

Thompson A.R.;Gill J.C.;Ewenstein B.M.;Mueller-Velten G.;Schwartz B.A.;Abshire T.;Ambinder R.;Angiolillo A.;Arkel Y.;Beardsley D.;Benjamin R.;Binder M.;Bobrow S.;Charbel F.;Cooper B.;Cornell N.;Czapek E.;Eisenberg P.;Ewenstein B.;Garcia-Ortiz S.;Gastineau D.;Gill J.;Green D.;Heggie G.;Heisel M.;Joist H.;Knupp C.;Lewis B.;Matthews D.;McKenna P.;Murukutla S.;Palascak J.;Penner J.;Powell J.;Ritter H.;Francisco R.;Shapiro A.;Silver B.;Simpson T.;Stanek M.;Thompson A.R.;Tongol J.;Waterbury L.;White G.;Young R. 01-01-2004. Successful treatment for patients with von Willebrand disease undergoing urgent surgery using factor Haemophilia, 10 1, 42-51

Gill J.;Ewenstein B.;Thompson A.;Mueller-Velten G.;Schwartz B.;Abshire T.;Ambinder R.;Angiolillo A.;Arkel Y.;Beardsley D.;Benjamin R.;Binder M.;Charbel F.;Cooper B.;Cornell N.;Czapek E.;Eisenberg P.;Ewenstein B.;Garcia-Ortiz S.;Gastineau D.;Gill J.;Heggie G.;Heisel M.;Joist H.;Knupp C.;Lewis B.;Matthews D.;McKenna P.;Murukutla S.;Palascak J.;Penner J.;Powell J.;Ritter H.;Francisco R.;Shapiro A.;Simpson T.;Stanek M.;Thompson A.;Tongol J.;Waterbury L.;White G.;Young R. 01-01-2003. Successful treatment of urgent bleeding in von Willebrand disease with factor VIII/VWF concentrate ( Haemophilia, 9 6, 688-695

Martinez J.;Palascak J.;Peters C. 01-01-1977. Functional and metabolic properties of human asialofibrinogen The Journal of Laboratory and Clinical Medicine, 89 2, 367-377

Cotto, M A; Lutomski, D M; Palascak, J E; Fant, W K; LaFrance, R J . Fat emulsion effects on prothrombin time in warfarin anticoagulated patients: an in vitro study. JPEN. Journal of parenteral and enteral nutrition, 14 2, 201-3

Lutomski, D M; Palascak, J E; Bower, R H . Warfarin resistance associated with intravenous lipid administration. JPEN. Journal of parenteral and enteral nutrition, 11 3, 316-8