Today is Sunday, Dec. 15, 2019

Department of Internal Medicine

Cardiovascular Health and Disease

Photo of  Richard Becker, MD

Richard Becker, MD

Mabel Stonehill Endowed Professor of Medicine, University of Cincinnati College of Medicine; Chief, Division of Cardiovascular Health and Disease; Director and Physician-in-Chief, UC Heart, Lung and Vascular Institute; Director of Cardiovascular Services, UC Health

Education/Credentials
  • Medical Degree: University of Cincinnati College of Medicine
  • Residency, Internal Medicine: Cleveland Clinic Foundation
  • Fellowship, Cardiovascular Disease: University of Massachusetts Medical School

Research/Clinical Interests

My research focuses on platelets, coagulation proteins, nucleic acids, cell-free DNA-histone complexes and oligonucleotides as reversible antithrombotic agents. http://uchealth.com/physician/richard-becker/

Board Certifications & Licenses
  • American Board of Internal Medicine (Cardiovascular Disease) 11/06/1991
  • American Board of Internal Medicine 09/10/1986
Contact Information
  • University of Cincinnati College of Medicine
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513.558.1067
  • Fax 513.558.2884
  • Email richard.becker@uc.edu

Peer Reviewed Publications

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Balla, Somasekhara R; Cyr, Derek D; Lokhnygina, Yuliya; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Fox, Keith A A; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Mahaffey, Kenneth W; Nessel, Christopher C; Piccini, Jonathan P; Singer, Daniel E; Patel, Manesh R 2017. Relation of Risk of Stroke in Patients With Atrial Fibrillation to Body Mass Index (from Patients Treated With Rivaroxaban and Warfarin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation Trial). The American journal of cardiology, 119 12, 1989-1996

Ducrocq, Gregory; Schulte, Phillip J; Budaj, Andrzej; Cornel, Jan H; Held, Claes; Himmelmann, Anders; Husted, Steen; Storey, Robert F; Cannon, Christopher P; Becker, Richard C; James, Stefan K; Katus, Hugo A; Lopes, Renato D; Sorbets, Emmanuel; Wallentin, Lars; Steg, Philippe Gabriel 2017. Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes. American heart journal, 186 , 91-99

Feigal, Jacob P; Boyle, Stephen H; Samad, Zainab; Velazquez, Eric J; Wilson, Jennifer L; Becker, Richard C; Williams, Redford B; Kuhn, Cynthia M; Ortel, Thomas L; Rogers, Joseph G; O'Connor, Christopher M; Jiang, Wei 2017. Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia. Journal of psychosomatic research, 93 , 14-18

Jiang, Rong; Babyak, Michael A; Brummett, Beverly H; Hauser, Elizabeth R; Shah, Svati H; Becker, Richard C; Siegler, Ilene C; Singh, Abanish; Haynes, Carol; Chryst-Ladd, Megan; Craig, Damian M; Williams, Redford B 2017. Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort. American heart journal, 190 , 40-45

Johnson, David A; Lieberman, David; Inadomi, John M; Ladabaum, Uri; Becker, Richard C; Gross, Seth A; Hood, Kristin L; Kushins, Susan; Pochapin, Mark; Robertson, Douglas J 2017. Increased Post-procedural Non-gastrointestinal Adverse Events After Outpatient Colonoscopy in High-risk Patients. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 15 6, 883-891.e9

Leef, George C; Hellkamp, Anne S; Patel, Manesh R; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Halperin, Jonathan L; Hankey, Graeme J; Hacke, Werner; Nessel, Christopher C; Singer, Daniel E; Fox, Keith A A; Mahaffey, Kenneth W; Piccini, Jonathan P 2017. Safety and Efficacy of Rivaroxaban in Patients With Cardiac Implantable Electronic Devices: Observations From the ROCKET AF Trial. Journal of the American Heart Association, 6 6,

Lindholm, Daniel; Hagström, Emil; James, Stefan K; Becker, Richard C; Cannon, Christopher P; Himmelmann, Anders; Katus, Hugo A; Maurer, Gerald; López-Sendón, José Luis; Steg, Philippe Gabriel; Storey, Robert F; Siegbahn, Agneta; Wallentin, Lars 2017. Growth Differentiation Factor 15 at 1 Month After an Acute Coronary Syndrome Is Associated With Increased Risk of Major Bleeding. Journal of the American Heart Association, 6 4,

Lindholm, Daniel; James, Stefan K; Bertilsson, Maria; Becker, Richard C; Cannon, Christopher P; Giannitsis, Evangelos; Harrington, Robert A; Himmelmann, Anders; Kontny, Frederic; Siegbahn, Agneta; Steg, Philippe Gabriel; Storey, Robert F; Velders, Matthijs A; Weaver, W Douglas; Wallentin, Lars 2017. Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome. Clinical chemistry, 63 2, 573-584

Lindner, Samuel M; Fordyce, Christopher B; Hellkamp, Anne S; Lokhnygina, Yuliya; Piccini, Jonathan P; Breithardt, Günter; Mahaffey, Kenneth W; Singer, Daniel E; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Berkowitz, Scott D; Nessel, Christopher C; Becker, Richard C; Fox, Keith A A; Patel, Manesh R 2017. Treatment Consistency Across Levels of Baseline Renal Function With Rivaroxaban or Warfarin: A ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) Analysis. Circulation, 135 10, 1001-1003

Lowenstern, Angela; Storey, Robert F; Neely, Megan; Sun, Jie-Lena; Angiolillo, Dominick J; Cannon, Christopher P; Himmelmann, Anders; Huber, Kurt; James, Stefan K; Katus, Hugo A; Morais, Joao; Siegbahn, Agneta; Steg, Phillippe Gabriel; Wallentin, Lars; Becker, Richard C 2017. Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome. Journal of thrombosis and thrombolysis, 44 2, 145-153

Nimjee, Shahid M; White, Rebekah R; Becker, Richard C; Sullenger, Bruce A 2017. Aptamers as Therapeutics. Annual review of pharmacology and toxicology, 57 , 61-79

Pollack, Charles V; Davoudi, Farideh; Diercks, Deborah B; Becker, Richard C; James, Stefan K; Lim, Soo Teik; Schulte, Phillip J; Spinar, Jindrich; Steg, Philippe Gabriel; Storey, Robert F; Himmelmann, Anders; Wallentin, Lars; Cannon, Christopher P 2017. Relative efficacy and safety of ticagelor vs clopidogrel as a function of time to invasive management in non-ST-segment elevation acute coronary syndrome in the PLATO trial. Clinical cardiology, 40 6, 390-398

Staudacher, Dawid L; Putz, Vera; Heger, Lukas; Reinöhl, Jochen; Hortmann, Marcus; Zelenkofske, Steven L; Becker, Richard C; Rusconi, Christopher P; Bode, Christoph; Ahrens, Ingo 2017. Direct factor IXa inhibition with the RNA-aptamer pegnivacogin reduces platelet reactivity in vitro and residual platelet aggregation in patients with acute coronary syndromes. European heart journal. Acute cardiovascular care, , 2048872617703065

Sun, Julia L; Boyle, Stephen H; Samad, Zainab; Babyak, Michael A; Wilson, Jennifer L; Kuhn, Cynthia; Becker, Richard C; Ortel, Thomas L; Williams, Redford B; Rogers, Joseph G; O'Connor, Christopher M; Velazquez, Eric J; Jiang, Wei 2017. Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients. European journal of preventive cardiology, 24 6, 591-599

Sun, Yihong; Hu, Dayi; Stevens, Susanna; Lokhnygina, Yuliya; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Mahaffey, Kenneth W; Nessel, Christopher C; Piccini, Jonathan P; Singer, Daniel E; Fox, Keith A A; Patel, Manesh R 2017. Efficacy and safety of rivaroxaban versus warfarin in patients from mainland China with nonvalvular atrial fibrillation: A subgroup analysis from the ROCKET AF trial. Thrombosis research, 156 , 184-190

Washam, Jeffrey B; Hellkamp, Anne S; Lokhnygina, Yuliya; Piccini, Jonathan P; Berkowitz, Scott D; Nessel, Christopher C; Becker, Richard C; Breithardt, Günter; Fox, Keith A A; Halperin, Jonathan L; Hankey, Graeme J; Mahaffey, Kenneth W; Singer, Daniel E; Patel, Manesh R 2017. Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial). The American journal of cardiology, 120 4, 588-594

Abo-Salem, Elsayed; Becker, Richard C 2016. Reversal of novel oral anticoagulants. Current opinion in pharmacology, 27 , 86-91

Björquist, Anna; Di Buduo, Christian A; Femia, Eti A; Storey, Robert F; Becker, Richard C; Balduini, Alessandra; Nylander, Sven; Cattaneo, Marco 2016. Studies of the interaction of ticagrelor with the P2Y13 receptor and with P2Y13-dependent pro-platelet formation by human megakaryocytes. Thrombosis and haemostasis, 116 6, 1079-1088

Breithardt, Günter; Baumgartner, Helmut; Berkowitz, Scott D; Hellkamp, Anne S; Piccini, Jonathan P; Lokhnygina, Yuliya; Halperin, Jonathan L; Singer, Daniel E; Hankey, Graeme J; Hacke, Werner; Becker, Richard C; Nessel, Christopher C; Mahaffey, Kenneth W; Califf, Robert M; Fox, Keith A A; Patel, Manesh R 2016. Native valve disease in patients with non-valvular atrial fibrillation on warfarin or rivaroxaban. Heart (British Cardiac Society), 102 13, 1036-43

DeVore, Adam D; Hellkamp, Anne S; Becker, Richard C; Berkowitz, Scott D; Breithardt, Guenter; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Mahaffey, Kenneth W; Nessel, Christopher C; Singer, Daniel E; Fox, Keith A A; Patel, Manesh R; Piccini, Jonathan P 2016. Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 18 8, 1135-42

Fordyce, Christopher B; Hellkamp, Anne S; Lokhnygina, Yuliya; Lindner, Samuel M; Piccini, Jonathan P; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Fox, Keith A A; Mahaffey, Kenneth W; Nessel, Christopher C; Singer, Daniel E; Patel, Manesh R 2016. On-Treatment Outcomes in Patients With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF. Circulation, 134 1, 37-47

Johansson, Åsa; Eriksson, Niclas; Lindholm, Daniel; Varenhorst, Christoph; James, Stefan; Syvänen, Ann-Christine; Axelsson, Tomas; Siegbahn, Agneta; Barratt, Bryan J; Becker, Richard C; Himmelmann, Anders; Katus, Hugo A; Steg, Philippe Gabriel; Storey, Robert F; Wallentin, Lars 2016. Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome. Human molecular genetics, 25 7, 1447-56

Kayse, Regina; Becker, Richard C 2016. The case for preoperative aspirin administration in patients undergoing elective CABG: is it open or closed? Annals of translational medicine, 4 Suppl 1, S26

Kim, Joonseok; Becker, Richard C 2016. Aspirin dosing frequency in the primary and secondary prevention of cardiovascular events. Journal of thrombosis and thrombolysis, ,

Muntner, Paul; Becker, Richard C; Calhoun, David; Chen, Daian; Cowley, Allen W; Flynn, Joseph T; Grobe, Justin L; Kidambi, Srividya; Kotchen, Theodore A; Lackland, Daniel T; Leslie, Kimberly K; Li, Yingchuan; Liang, Mingyu; Lloyd, Augusta; Mattson, David L; Mendizabal, Brenda; Mitsnefes, Mark; Nair, Anand; Pierce, Gary L; Pollock, Jennifer S; Safford, Monika M; Santillan, Mark K; Sigmund, Curt D; Thomas, Stephen J; Urbina, Elaine M 2016. Introduction to the American Heart Association's Hypertension Strategically Focused Research Network. Hypertension (Dallas, Tex. : 1979), 67 4, 674-80

Nimjee, Shahid M; Povsic, Thomas J; Sullenger, Bruce A; Becker, Richard C 2016. Translation and Clinical Development of Antithrombotic Aptamers. Nucleic acid therapeutics, 26 3, 147-55

Piccini, Jonathan P; Hellkamp, Anne S; Washam, Jeffrey B; Becker, Richard C; Breithardt, Günter; Berkowitz, Scott D; Halperin, Jonathan L; Hankey, Graeme J; Hacke, Werner; Mahaffey, Kenneth W; Nessel, Christopher C; Singer, Daniel E; Fox, Keith A A; Patel, Manesh R 2016. Response by Piccini et al to Letters Regarding Article, "Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation". Circulation, 134 2, e7-8

Pokorney, Sean D; Piccini, Jonathan P; Stevens, Susanna R; Patel, Manesh R; Pieper, Karen S; Halperin, Jonathan L; Breithardt, Günter; Singer, Daniel E; Hankey, Graeme J; Hacke, Werner; Becker, Richard C; Berkowitz, Scott D; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M 2016. Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF. Journal of the American Heart Association, 5 3, e002197

Povsic, Thomas J; Lawrence, Monica G; Lincoff, A Michael; Mehran, Roxana; Rusconi, Christopher P; Zelenkofske, Steven L; Huang, Zhen; Sailstad, Jeffrey; Armstrong, Paul W; Steg, P Gabriel; Bode, Christoph; Becker, Richard C; Alexander, John H; Adkinson, N Franklin; Levinson, Arnold I 2016. Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. The Journal of allergy and clinical immunology, 138 6, 1712-1715

Ruff, Christian T; Ansell, Jack E; Becker, Richard C; Benjamin, Emelia J; Deicicchi, David J; Mark Estes, N A; Ezekowitz, Michael D; Fanikos, John; Fareed, Jawed; Garcia, David; Giugliano, Robert P; Goldhaber, Samuel Z; Granger, Christopher; Healey, Jeff S; Hull, Russell; Hylek, Elaine M; Libby, Peter; Lopes, Renato D; Mahaffey, Kenneth W; Mega, Jessica; Piazza, Gregory; Sasahara, Arthur A; Sorond, Farzaneh A; Spyropoulos, Alex C; Walenga, Jeanine M; Weitz, Jeffrey I 2016. North American Thrombosis Forum, AF Action Initiative Consensus Document. The American journal of medicine, 129 5 Suppl, S1-S29

Shah, Rohan; Hellkamp, Anne; Lokhnygina, Yuliya; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Fox, Keith A A; Nessel, Christopher C; Mahaffey, Kenneth W; Piccini, Jonathan P; Singer, Daniel E; Patel, Manesh R 2016. Use of concomitant aspirin in patients with atrial fibrillation: Findings from the ROCKET AF trial. American heart journal, 179 , 77-86

Sherwood, Matthew W; Cyr, Derek D; Jones, W Schuyler; Becker, Richard C; Berkowitz, Scott D; Washam, Jeffrey B; Breithardt, Günter; Fox, Keith A A; Halperin, Jonathan L; Hankey, Graeme J; Singer, Daniel E; Piccini, Jonathan P; Nessel, Christopher C; Mahaffey, Kenneth W; Patel, Manesh R 2016. Use of Dual Antiplatelet Therapy and Patient Outcomes in Those Undergoing Percutaneous Coronary Intervention: The ROCKET AF Trial. JACC. Cardiovascular interventions, 9 16, 1694-702

Shimada, Yuichi J; Bansilal, Sameer; Wiviott, Stephen D; Becker, Richard C; Harrington, Robert A; Himmelmann, Anders; Neely, Benjamin; Husted, Steen; James, Stefan K; Katus, Hugo A; Lopes, Renato D; Steg, Ph Gabriel; Storey, Robert F; Wallentin, Lars; Cannon, Christopher P 2016. Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial. American heart journal, 177 , 1-8

Vemulapalli, Sreekanth; Hellkamp, Anne S; Jones, W Schuyler; Piccini, Jonathan P; Mahaffey, Kenneth W; Becker, Richard C; Hankey, Graeme J; Berkowitz, Scott D; Nessel, Christopher C; Breithardt, Günter; Singer, Daniel E; Fox, Keith A A; Patel, Manesh R 2016. Blood pressure control and stroke or bleeding risk in anticoagulated patients with atrial fibrillation: Results from the ROCKET AF Trial. American heart journal, 178 , 74-84

Bansilal, Sameer; Bloomgarden, Zachary; Halperin, Jonathan L; Hellkamp, Anne S; Lokhnygina, Yuliya; Patel, Manesh R; Becker, Richard C; Breithardt, Günter; Hacke, Werner; Hankey, Graeme J; Nessel, Christopher C; Singer, Daniel E; Berkowitz, Scott D; Piccini, Jonathan P; Mahaffey, Kenneth W; Fox, Keith A A 2015. Efficacy and safety of rivaroxaban in patients with diabetes and nonvalvular atrial fibrillation: the Rivaroxaban Once-daily, Oral, Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF Trial). American heart journal, 170 4, 675-682.e8

Becker, Richard A; Ankley, Gerald T; Edwards, Stephen W; Kennedy, Sean W; Linkov, Igor; Meek, Bette; Sachana, Magdalini; Segner, Helmut; Van Der Burg, Bart; Villeneuve, Daniel L; Watanabe, Haruna; Barton-Maclaren, Tara S 2015. Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence. Regulatory toxicology and pharmacology : RTP, 72 3, 514-37

Becker, Richard A; Friedman, Katie Paul; Simon, Ted W; Marty, M Sue; Patlewicz, Grace; Rowlands, J Craig 2015. An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity--proof of concept. Regulatory toxicology and pharmacology : RTP, 71 3, 398-408

Becker, Richard A; Patlewicz, Grace; Simon, Ted W; Rowlands, J Craig; Budinsky, Robert A 2015. The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor. Regulatory toxicology and pharmacology : RTP, 73 1, 172-90

Becker, Richard C 2015. The biochemistry, enzymology and pharmacology of non-vitamin K anticoagulant drug reversal agents and antidotes. Journal of thrombosis and thrombolysis, ,

Becker, Richard C 2015. Measurement tools and antidotes for non-vitamin K oral anticoagulants. Journal of thrombosis and thrombolysis, ,

Becker, Richard C; Helmy, Tarek 2015. Are at least 12 months of dual antiplatelet therapy needed for all patients with drug-eluting stents? Not all patients with drug-eluting stents need at least 12 months of dual antiplatelet therapy. Circulation, 131 22, 2010-9; discussion 2

Borgert, Christopher J; Wise, Kimberly; Becker, Richard A 2015. Modernizing problem formulation for risk assessment necessitates articulation of mode of action. Regulatory toxicology and pharmacology : RTP, 72 3, 538-51

Douketis, James D; Spyropoulos, Alex C; Kaatz, Scott; Becker, Richard C; Caprini, Joseph A; Dunn, Andrew S; Garcia, David A; Jacobson, Alan; Jaffer, Amir K; Kong, David F; Schulman, Sam; Turpie, Alexander G G; Hasselblad, Vic; Ortel, Thomas L 2015. Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation. The New England journal of medicine, 373 9, 823-33

Ducrocq, Gregory; Schulte, Phillip J; Becker, Richard C; Cannon, Christopher P; Harrington, Robert A; Held, Claes; Himmelmann, Anders; Lassila, Riitta; Storey, Robert F; Sorbets, Emmanuel; Wallentin, Lars; Steg, Philippe Gabriel 2015. Association of spontaneous and procedure-related bleeds with short- and long-term mortality after acute coronary syndromes: an analysis from the PLATO trial. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 11 8, 737-45

Ganjehei, Leila; Becker, Richard C 2015. Aspirin dosing in cardiovascular disease prevention and management: an update. Journal of thrombosis and thrombolysis, 40 4, 499-511

Hagström, Emil; James, Stefan K; Bertilsson, Maria; Becker, Richard C; Himmelmann, Anders; Husted, Steen; Katus, Hugo A; Steg, Philippe Gabriel; Storey, Robert F; Siegbahn, Agneta; Wallentin, Lars 2015. Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study. European heart journal, ,

Jiang, Wei; Boyle, Stephen H; Ortel, Thomas L; Samad, Zainab; Velazquez, Eric J; Harrison, Robert W; Wilson, Jennifer; Kuhn, Cynthia; Williams, Redford B; O'Connor, Christopher M; Becker, Richard C 2015. Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study. American heart journal, 169 4, 496-507.e1

Johansson, Åsa; Eriksson, Niclas; Becker, Richard C; Storey, Robert F; Himmelmann, Anders; Hagström, Emil; Varenhorst, Christoph; Axelsson, Tomas; Barratt, Bryan J; James, Stefan K; Katus, Hugo A; Steg, Philippe Gabriel; Syvänen, Ann-Christine; Wallentin, Lars; Siegbahn, Agneta 2015. NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO). Circulation. Cardiovascular genetics, 8 3, 498-506

Kang, Hyun-Jae; Clare, Robert M; Gao, Runlin; Held, Claes; Himmelmann, Anders; James, Stefan K; Lim, Soo Teik; Santoso, Anwar; Yu, Cheuk-Man; Wallentin, Lars; Becker, Richard C 2015. Ticagrelor versus clopidogrel in Asian patients with acute coronary syndrome: A retrospective analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial. American heart journal, 169 6, 899-905.e1

Krishnamoorthy, Arun; Sherwood, Matthew W; Lopes, Renato D; Becker, Richard C 2015. The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials. American heart journal, 169 3, 315-22

Lincoff, A Michael; Mehran, Roxana; Povsic, Thomas J; Zelenkofske, Steven L; Huang, Zhen; Armstrong, Paul W; Steg, P Gabriel; Bode, Christoph; Cohen, Mauricio G; Buller, Christopher; Laanmets, Peep; Valgimigli, Marco; Marandi, Toomas; Fridrich, Viliam; Cantor, Warren J; Merkely, Bela; Lopez-Sendon, Jose; Cornel, Jan H; Kasprzak, Jaroslaw D; Aschermann, Michael; Guetta, Victor; Morais, Joao; Sinnaeve, Peter R; Huber, Kurt; Stables, Rod; Sellers, Mary Ann; Borgman, Marilyn; Glenn, Lauren; Levinson, Arnold I; Lopes, Renato D; Hasselblad, Vic; Becker, Richard C; Alexander, John H 2015. Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial. Lancet (London, England), ,

Mahaffy, P R; Webster, C R; Stern, J C; Brunner, A E; Atreya, S K; Conrad, P G; Domagal-Goldman, S; Eigenbrode, J L; Flesch, G J; Christensen, L E; Franz, H B; Freissinet, C; Glavin, D P; Grotzinger, J P; Jones, J H; Leshin, L A; Malespin, C; McAdam, A C; Ming, D W; Navarro-Gonzalez, R; Niles, P B; Owen, T; Pavlov, A A; Steele, A; Trainer, M G; Williford, K H; Wray, J J 2015. Mars atmosphere. The imprint of atmospheric evolution in the D/H of Hesperian clay minerals on Mars. Science (New York, N.Y.), 347 6220, 412-4

Patlewicz, Grace; Simon, Ted W; Rowlands, J Craig; Budinsky, Robert A; Becker, Richard A 2015. Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes. Regulatory toxicology and pharmacology : RTP, 71 3, 463-77

Piccini, Jonathan P; Hellkamp, Anne S; Washam, Jeffrey B; Becker, Richard C; Breithardt, Günter; Berkowitz, Scott D; Halperin, Jonathan L; Hankey, Graeme J; Hacke, Werner; Mahaffey, Kenneth W; Nessel, Christopher C; Singer, Daniel E; Fox, Keith A A; Patel, Manesh R 2015. Polypharmacy and the Efficacy and Safety of Rivaroxaban versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation. Circulation, ,

Plunkett, Laura M; Kaplan, A Michael; Becker, Richard A 2015. Challenges in using the ToxRefDB as a resource for toxicity prediction modeling. Regulatory toxicology and pharmacology : RTP, 72 3, 610-4

Sherwood, Matthew W; Nessel, Christopher C; Hellkamp, Anne S; Mahaffey, Kenneth W; Piccini, Jonathan P; Suh, Eun-Young; Becker, Richard C; Singer, Daniel E; Halperin, Jonathan L; Hankey, Graeme J; Berkowitz, Scott D; Fox, Keith A A; Patel, Manesh R 2015. Gastrointestinal Bleeding in Patients With Atrial Fibrillation Treated With Rivaroxaban or Warfarin: ROCKET AF Trial. Journal of the American College of Cardiology, 66 21, 2271-81

Singer, Daniel E; Hellkamp, Anne S; Yuan, Zhong; Lokhnygina, Yuliya; Patel, Manesh R; Piccini, Jonathan P; Hankey, Graeme J; Breithardt, Günter; Halperin, Jonathan L; Becker, Richard C; Hacke, Werner; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M 2015. Alternative calculations of individual patient time in therapeutic range while taking warfarin: results from the ROCKET AF trial. Journal of the American Heart Association, 4 3, e001349

Steinberg, Benjamin A; Hellkamp, Anne S; Lokhnygina, Yuliya; Patel, Manesh R; Breithardt, Günter; Hankey, Graeme J; Becker, Richard C; Singer, Daniel E; Halperin, Jonathan L; Hacke, Werner; Nessel, Christopher C; Berkowitz, Scott D; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M; Piccini, Jonathan P 2015. Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial. European heart journal, 36 5, 288-96

Varenhorst, Christoph; Eriksson, Niclas; Johansson, Åsa; Barratt, Bryan J; Hagström, Emil; Åkerblom, Axel; Syvänen, Ann-Christine; Becker, Richard C; James, Stefan K; Katus, Hugo A; Husted, Steen; Steg, Ph Gabriel; Siegbahn, Agneta; Voora, Deepak; Teng, Renli; Storey, Robert F; Wallentin, Lars 2015. Effect of genetic variations on ticagrelor plasma levels and clinical outcomes. European heart journal, 36 29, 1901-12

Velders, Matthijs A; Wallentin, Lars; Becker, Richard C; van Boven, Adrianus J; Himmelmann, Anders; Husted, Steen; Katus, Hugo A; Lindholm, Daniel; Morais, Joao; Siegbahn, Agneta; Storey, Robert F; Wernroth, Lisa; James, Stefan K 2015. Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: Insights from the Platelet Inhibition and Patient Outcomes trial. American heart journal, 169 6, 879-889.e7

Webster, Christopher R; Mahaffy, Paul R; Atreya, Sushil K; Flesch, Gregory J; Mischna, Michael A; Meslin, Pierre-Yves; Farley, Kenneth A; Conrad, Pamela G; Christensen, Lance E; Pavlov, Alexander A; Martín-Torres, Javier; Zorzano, María-Paz; McConnochie, Timothy H; Owen, Tobias; Eigenbrode, Jennifer L; Glavin, Daniel P; Steele, Andrew; Malespin, Charles A; Archer, P Douglas; Sutter, Brad; Coll, Patrice; Freissinet, Caroline; McKay, Christopher P; Moores, John E; Schwenzer, Susanne P; Bridges, John C; Navarro-Gonzalez, Rafael; Gellert, Ralf; Lemmon, Mark T 2015. Mars atmosphere. Mars methane detection and variability at Gale crater. Science (New York, N.Y.), 347 6220, 415-7

Abo-Salem, Elsayed; Becker, Richard 2014. Transitioning to and from the novel oral anticoagulants: a management strategy for clinicians. Journal of thrombosis and thrombolysis, 37 3, 372-9

Ahmad, Tariq; Becker, Richard C 2014. The unmet need for philanthropic funding of early career cardiovascular investigators. Journal of thrombosis and thrombolysis, 37 4, 527-31

Akerblom, Axel; Eriksson, Niclas; Wallentin, Lars; Siegbahn, Agneta; Barratt, Bryan J; Becker, Richard C; Budaj, Andrzej; Himmelmann, Anders; Husted, Steen; Storey, Robert F; Johansson, Asa; James, Stefan K 2014. Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study. American heart journal, 168 1, 96-102.e2

Becker, Richard C 2014. Editor's page. Journal of thrombosis and thrombolysis, 37 2, 216

Breithardt, Günter; Baumgartner, Helmut; Berkowitz, Scott D; Hellkamp, Anne S; Piccini, Jonathan P; Stevens, Susanna R; Lokhnygina, Yuliya; Patel, Manesh R; Halperin, Jonathan L; Singer, Daniel E; Hankey, Graeme J; Hacke, Werner; Becker, Richard C; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M 2014. Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial. European heart journal, 35 47, 3377-85

Daly, Patrick L; Becker, Richard C 2014. Pharmacogenetics of antiplatelet therapy. Current atherosclerosis reports, 16 5, 411

Goodman, Shaun G; Wojdyla, Daniel M; Piccini, Jonathan P; White, Harvey D; Paolini, John F; Nessel, Christopher C; Berkowitz, Scott D; Mahaffey, Kenneth W; Patel, Manesh R; Sherwood, Matthew W; Becker, Richard C; Halperin, Jonathan L; Hacke, Werner; Singer, Daniel E; Hankey, Graeme J; Breithardt, Gunter; Fox, Keith A A; Califf, Robert M 2014. Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation). Journal of the American College of Cardiology, 63 9, 891-900

Halperin, Jonathan L; Hankey, Graeme J; Wojdyla, Daniel M; Piccini, Jonathan P; Lokhnygina, Yuliya; Patel, Manesh R; Breithardt, Günter; Singer, Daniel E; Becker, Richard C; Hacke, Werner; Paolini, John F; Nessel, Christopher C; Mahaffey, Kenneth W; Califf, Robert M; Fox, Keith A A 2014. Efficacy and Safety of Rivaroxaban Compared With Warfarin Among Elderly Patients With Nonvalvular Atrial Fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). Circulation, 130 2, 138-46

Hankey, Graeme J; Stevens, Susanna R; Piccini, Jonathan P; Lokhnygina, Yuliya; Mahaffey, Kenneth W; Halperin, Jonathan L; Patel, Manesh R; Breithardt, Günter; Singer, Daniel E; Becker, Richard C; Berkowitz, Scott D; Paolini, John F; Nessel, Christopher C; Hacke, Werner; Fox, Keith A A; Califf, Robert M 2014. Intracranial hemorrhage among patients with atrial fibrillation anticoagulated with warfarin or rivaroxaban: the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation. Stroke; a journal of cerebral circulation, 45 5, 1304-12

Husted, Steen; James, Stefan K; Bach, Richard G; Becker, Richard C; Budaj, Andrzej; Heras, Magda; Himmelmann, Anders; Horrow, Jay; Katus, Hugo A; Lassila, Riita; Morais, Joao; Nicolau, José C; Steg, Ph Gabriel; Storey, Robert F; Wojdyla, Daniel; Wallentin, Lars 2014. The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial. European heart journal, 35 23, 1541-50

Mahaffey, Kenneth W; Held, Claes; Wojdyla, Daniel M; James, Stefan K; Katus, Hugo A; Husted, Steen; Steg, Philippe Gabriel; Cannon, Christopher P; Becker, Richard C; Storey, Robert F; Khurmi, Nardev S; Nicolau, José C; Yu, Cheuk-Man; Ardissino, Diego; Budaj, Andrzej; Morais, Joao; Montgomery, Debra; Himmelmann, Anders; Harrington, Robert A; Wallentin, Lars 2014. Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial. Journal of the American College of Cardiology, 63 15, 1493-9

Patel, Manesh R; Becker, Richard C; Wojdyla, Daniel M; Emanuelsson, Hakan; Hiatt, William R; Horrow, Jay; Husted, Steen; Mahaffey, Kenneth W; Steg, P Gabriel; Storey, Robert F; Wallentin, Lars; James, Stefan K 2014. Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial. European journal of preventive cardiology, ,

Patlewicz, Grace; Ball, Nicholas; Becker, Richard A; Booth, Ewan D; Cronin, Mark T D; Kroese, Dinant; Steup, David; van Ravenzwaay, Ben; Hartung, Thomas 2014. Read-across approaches--misconceptions, promises and challenges ahead. ALTEX, 31 4, 387-96

Piccini, Jonathan P; Garg, Jyotsna; Patel, Manesh R; Lokhnygina, Yuliya; Goodman, Shaun G; Becker, Richard C; Berkowitz, Scott D; Breithardt, Günter; Hacke, Werner; Halperin, Jonathan L; Hankey, Graeme J; Nessel, Christopher C; Mahaffey, Kenneth W; Singer, Daniel E; Califf, Robert M; Fox, Keith A A 2014. Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial. European heart journal, 35 28, 1873-80

Piccini, Jonathan P; Hellkamp, Anne S; Lokhnygina, Yuliya; Patel, Manesh R; Harrell, Frank E; Singer, Daniel E; Becker, Richard C; Breithardt, Günter; Halperin, Jonathan L; Hankey, Graeme J; Berkowitz, Scott D; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M 2014. Relationship between time in therapeutic range and comparative treatment effect of rivaroxaban and warfarin: results from the ROCKET AF trial. Journal of the American Heart Association, 3 2, e000521

Povsic, Thomas J; Vavalle, John P; Alexander, John H; Aberle, Laura H; Zelenkofske, Steven L; Becker, Richard C; Buller, Christopher E; Cohen, Mauricio G; Cornel, Jan H; Kasprzak, Jaroslaw D; Montalescot, Gilles; Fail, Peter S; Sarembock, Ian J; Mehran, Roxana 2014. Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, ,

Samad, Zainab; Boyle, Stephen; Ersboll, Mads; Vora, Amit N; Zhang, Ye; Becker, Richard C; Williams, Redford; Kuhn, Cynthia; Ortel, Thomas L; Rogers, Joseph G; O'Connor, Christopher M; Velazquez, Eric J; Jiang, Wei 2014. Sex differences in platelet reactivity and cardiovascular and psychological response to mental stress in patients with stable ischemic heart disease: insights from the REMIT study. Journal of the American College of Cardiology, 64 16, 1669-78

Schlaudecker, Jeffrey; Becker, Richard 2014. Inflammatory response and thrombosis in older individuals. Seminars in thrombosis and hemostasis, 40 6, 669-74

Sherwood, Matthew W; Douketis, James D; Patel, Manesh R; Piccini, Jonathan P; Hellkamp, Anne S; Lokhnygina, Yuliya; Spyropoulos, Alex C; Hankey, Graeme J; Singer, Daniel E; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M; Becker, Richard C 2014. Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF). Circulation, 129 18, 1850-9

Smiley, Dia A; Becker, Richard C 2014. Factor IXa as a target for anticoagulation in thrombotic disorders and conditions. Drug discovery today, ,

Steinberg, Benjamin A; Hellkamp, Anne S; Lokhnygina, Yuliya; Halperin, Jonathan L; Breithardt, Günter; Passman, Rod; Hankey, Graeme J; Patel, Manesh R; Becker, Richard C; Singer, Daniel E; Hacke, Werner; Berkowitz, Scott D; Nessel, Christopher C; Mahaffey, Kenneth W; Fox, Keith A A; Califf, Robert M; Piccini, Jonathan P 2014. Use and outcomes of antiarrhythmic therapy in patients with atrial fibrillation receiving oral anticoagulation: results from the ROCKET AF trial. Heart rhythm : the official journal of the Heart Rhythm Society, 11 6, 925-32

Steinhubl, Steven R; Eikelboom, John W; Hylek, Elaine M; Dauerman, Harold L; Smyth, Susan S; Becker, Richard C 2014. Antiplatelet therapy in prevention of cardio- and venous thromboembolic events. Journal of thrombosis and thrombolysis, 37 3, 362-71

Storey, Robert F; Kotha, Jayaprakash; Smyth, Susan S; Moliterno, David J; Rorick, Tyrus L; Moccetti, Tiziano; Valgimigli, Marco; Dery, Jean Pierre; Cornel, Jan H; Thomas, Gregory S; Huber, Kurt; Harrington, Robert A; Hord, Edward; Judge, Heather M; Chen, Edmond; Strony, John; Mahaffey, Kenneth W; Tricoci, Pierluigi; Becker, Richard C; Jennings, Lisa K 2014. Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy. Thrombosis and haemostasis, 111 5, 883-91

Voora, Deepak; Becker, Richard C 2014. A freeze on tailored antiplatelet therapy? Circulation, 129 21, 2088-90

Wallentin, Lars; Becker, Richard C; Cannon, Christopher P; Held, Claes; Himmelmann, Anders; Husted, Steen; James, Stefan K; Katus, Hugo A; Mahaffey, Kenneth M; Pieper, Karen S; Storey, Robert F; Steg, Philippe Gabriel; Harrington, Robert A 2014. No misrepresentation of vital status follow-up in PLATO: Predefined analyses guarantee the integrity of the benefits of ticagrelor over clopidogrel in the PLATO trial: Commentary on: DiNicolantonio JJ, Tomek A, Misrepresentation of vital status follow-up: Challenging the integrity of the PLATO trial and the claimed mortality benefit of ticagrelor versus clopidogrel, International Journal of Cardiology, 2013 Serebruany VL. Discrepancies in the primary PLATO trial publication and the FDA reviews, International Journal of Cardiology, 2014. International journal of cardiology, ,

Wallentin, Lars; Becker, Richard C; Cannon, Christopher P; Held, Claes; Himmelmann, Anders; Husted, Steen; James, Stefan K; Katus, Hugo S; Mahaffey, Kenneth W; Pieper, Karen S; Storey, Robert F; Steg, Philippe Gabriel; Harrington, Robert A 2014. Review of the accumulated PLATO documentation supports reliable and consistent superiority of ticagrelor over clopidogrel in patients with acute coronary syndrome: Commentary on: DiNicolantonio JJ, Tomek A, Inactivations, deletions, non-adjudications, and downgrades of clinical endpoints on ticagrelor: serious concerns over the reliability of the PLATO trial, International Journal of Cardiology, 2013. International journal of cardiology, 170 3, e59-62

Wallentin, Lars; Lindholm, Daniel; Siegbahn, Agneta; Wernroth, Lisa; Becker, Richard C; Cannon, Christopher P; Cornel, Jan H; Himmelmann, Anders; Giannitsis, Evangelos; Harrington, Robert A; Held, Claes; Husted, Steen; Katus, Hugo A; Mahaffey, Kenneth W; Steg, Ph Gabriel; Storey, Robert F; James, Stefan K 2014. Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation, 129 3, 293-303

Welsby, Ian J; Phillips-Bute, Barbara; Mathew, Joseph P; Newman, Mark F; Becker, Richard; Rao, Sunil; Milano, Carmelo A; Stafford-Smith, Mark 2014. ABO blood group influences transfusion and survival after cardiac surgery. Journal of thrombosis and thrombolysis, ,

Wisler, James W; Becker, Richard C 2014. Antithrombotic therapy: new areas to understand efficacy and bleeding. Expert opinion on therapeutic targets, 18 12, 1427-34

Wong, Ka Sing Lawrence; Hu, Dai Yi; Oomman, Abraham; Tan, Ru-San; Patel, Manesh R; Singer, Daniel E; Breithardt, Günter; Mahaffey, Kenneth W; Becker, Richard C; Califf, Robert; Fox, Keith A A; Berkowitz, Scott D; Hacke, Werner; Hankey, Graeme J 2014. Rivaroxaban for stroke prevention in East Asian patients from the ROCKET AF trial. Stroke; a journal of cerebral circulation, 45 6, 1739-47

Åkerblom, Axel; Wallentin, Lars; Larsson, Anders; Siegbahn, Agneta; Becker, Richard C; Budaj, Andrzej; Himmelmann, Anders; Horrow, Jay; Husted, Steen; Storey, Robert F; Asenblad, Nils; James, Stefan K 2013. Cystatin C- and creatinine-based estimates of renal function and their value for risk prediction in patients with acute coronary syndrome: results from the PLATelet Inhibition and Patient Outcomes (PLATO) study. Clinical chemistry, 59 9, 1369-75

Becker, Richard C 2013. A thought experiment in contemporary drug development: informed bench-to-bedside strategies. Journal of the American Heart Association, 2 1, e000031

Berger, Jeffrey S; Becker, Richard C; Kuhn, Cynthia; Helms, Michael J; Ortel, Thomas L; Williams, Redford 2013. Hyperreactive platelet phenotypes: relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co-stimulation. Thrombosis and haemostasis, 109 1, 85-92

Bernacki, Gwen M; Becker, Richard C 2013. Oral anticoagulants in older adults with atrial fibrillation. Journal of thrombosis and thrombolysis, ,

Brummett, Beverly H; Babyak, Michael A; Jiang, Rong; Shah, Svati H; Becker, Richard C; Haynes, Carol; Chryst-Ladd, Megan; Craig, Damian M; Hauser, Elizabeth R; Siegler, Ilene C; Kuhn, Cynthia M; Singh, Abanish; Williams, Redford B 2013. A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events. PloS one, 8 12, e82781

Dewald, Tracy A; Becker, Richard C 2013. The pharmacology of novel oral anticoagulants. Journal of thrombosis and thrombolysis, ,

Jackson, Larry R; Becker, Richard C 2013. Novel oral anticoagulants: pharmacology, coagulation measures, and considerations for reversal. Journal of thrombosis and thrombolysis, ,

James, Stefan K; Storey, Robert F; Pieper, Karen S; Cannon, Christopher P; Becker, Richard C; Steg, Philippe Gabriel; Wallentin, Lars; Harrington, Robert A 2013. Response to letter regarding article, "Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials". Stroke; a journal of cerebral circulation, 44 8, e95-6

Krishnan, Anandi; Vogler, Erwin A; Sullenger, Bruce A; Becker, Richard C 2013. The effect of surface contact activation and temperature on plasma coagulation with an RNA aptamer directed against factor IXa. Journal of thrombosis and thrombolysis, 35 1, 48-56

Mahaffey, Kenneth W; Wojdyla, Daniel; Hankey, Graeme J; White, Harvey D; Nessel, Christopher C; Piccini, Jonathan P; Patel, Manesh R; Berkowitz, Scott D; Becker, Richard C; Halperin, Jonathan L; Singer, Daniel E; Califf, Robert M; Fox, Keith A A; Breithardt, Günter; Hacke, Werner 2013. Clinical outcomes with rivaroxaban in patients transitioned from vitamin K antagonist therapy: a subgroup analysis of a randomized trial. Annals of internal medicine, 158 12, 861-8

Mentz, Robert J; Becker, Richard C 2013. Funding opportunities for clinical investigators in the early stages of career development in cardiovascular research. Journal of thrombosis and thrombolysis, ,

Patel, Manesh R; Hellkamp, Anne S; Lokhnygina, Yuliya; Piccini, Jonathan P; Zhang, Zhongxin; Mohanty, Surya; Singer, Daniel E; Hacke, Werner; Breithardt, Günter; Halperin, Jonathan L; Hankey, Graeme J; Becker, Richard C; Nessel, Christopher C; Berkowitz, Scott D; Califf, Robert M; Fox, Keith A A; Mahaffey, Kenneth W 2013. Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). Journal of the American College of Cardiology, 61 6, 651-8

Piccini, Jonathan P; Stevens, Susanna R; Chang, YuChiao; Singer, Daniel E; Lokhnygina, Yuliya; Go, Alan S; Patel, Manesh R; Mahaffey, Kenneth W; Halperin, Jonathan L; Breithardt, Günter; Hankey, Graeme J; Hacke, Werner; Becker, Richard C; Nessel, Christopher C; Fox, Keith A A; Califf, Robert M 2013. Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts. Circulation, 127 2, 224-32

Povsic, Thomas J; Vavalle, John P; Aberle, Laura H; Kasprzak, Jaroslaw D; Cohen, Mauricio G; Mehran, Roxana; Bode, Christoph; Buller, Christopher E; Montalescot, Gilles; Cornel, Jan H; Rynkiewicz, Andrzej; Ring, Michael E; Zeymer, Uwe; Natarajan, Madhu; Delarche, Nicolas; Zelenkofske, Steven L; Becker, Richard C; Alexander, John H 2013. A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial. European heart journal, 34 31, 2481-9

Rodés-Cabau, Josep; Dauerman, Harold L; Cohen, Mauricio G; Mehran, Roxana; Small, Eric M; Smyth, Susan S; Costa, Marco A; Mega, Jessica L; O'Donoghue, Michelle L; Ohman, E Magnus; Becker, Richard C 2013. Antithrombotic Treatment in Transcatheter Aortic Valve Implantation: Insights for Cerebrovascular and Bleeding Events. Journal of the American College of Cardiology, ,

Singer, Daniel E; Hellkamp, Anne S; Piccini, Jonathan P; Mahaffey, Kenneth W; Lokhnygina, Yuliya; Pan, Guohua; Halperin, Jonathan L; Becker, Richard C; Breithardt, Günter; Hankey, Graeme J; Hacke, Werner; Nessel, Christopher C; Patel, Manesh R; Califf, Robert M; Fox, Keith A A 2013. Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial. Journal of the American Heart Association, 2 1, e000067

Vavalle, John P; Povsic, Thomas J; Aberle, Laura H; Zelenkofske, Steven L; Mehran, Roxana; Kasprzak, Jaroslaw D; Bode, Christoph; Buller, Christopher E; Montalescot, Gilles; Cornel, Jan H; Becker, Richard C; Alexander, John H; Cohen, Mauricio G 2013. Safety of very early sheath removal in patients treated with REG1 for acute coronary syndromes: insights from the RADAR trial. The Journal of invasive cardiology, 25 11, 593-9

Voora, Deepak; Cyr, Derek; Lucas, Joseph; Chi, Jen-Tsan; Dungan, Jennifer; McCaffrey, Timothy A; Katz, Richard; Newby, L Kristin; Kraus, William E; Becker, Richard C; Ortel, Thomas L; Ginsburg, Geoffrey S 2013. Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. Journal of the American College of Cardiology, 62 14, 1267-76

Wong, Michael H; Atreya, Sushil K; Mahaffy, Paul N; Franz, Heather B; Malespin, Charles; Trainer, Melissa G; Stern, Jennifer C; Conrad, Pamela G; Manning, Heidi L K; Pepin, Robert O; Becker, Richard H; McKay, Christopher P; Owen, Tobias C; Navarro-González, Rafael; Jones, John H; Jakosky, Bruce M; Steele, Andrew 2013. Isotopes of nitrogen on Mars: Atmospheric measurements by?Curiosity's mass spectrometer. Geophysical research letters, 40 23, 6033-6037

Xu, Weixian; Holmes, Dajuanicia N; Becker, Richard C; Roe, Matthew T; Peterson, Eric D; Wang, Tracy Y 2013. Comparison of long-term outcomes between older Asian and white patients with non-ST-segment elevation myocardial infarction: findings from CRUSADE-CMS database. American heart journal, 166 6, 1050-5

Akerblom, Åxel; Wallentin, Lars; Siegbahn, Agneta; Becker, Richard C; Budaj, Andrzej; Buck, Kristen; Giannitsis, Evangelos; Horrow, Jay; Husted, Steen; Katus, Hugo A; Steg, Philippe Gabriel; Storey, Robert F; Åsenblad, Nils; James, Stefan K 2012. Cystatin C and estimated glomerular filtration rate as predictors for adverse outcome in patients with ST-elevation and non-ST-elevation acute coronary syndromes: results from the Platelet Inhibition and Patient Outcomes study. Clinical chemistry, 58 1, 190-9

Angiolillo, Dominick J; Schneider, David J; Bhatt, Deepak L; French, William J; Price, Matthew J; Saucedo, Jorge F; Shaburishvili, Tamaz; Huber, Kurt; Prats, Jayne; Liu, Tiepu; Harrington, Robert A; Becker, Richard C 2012. Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials. Journal of thrombosis and thrombolysis, 34 1, 44-55

Chan, Mark Y; Lin, Min; Lucas, Joseph; Moseley, Arthur; Thompson, J Will; Cyr, Derek; Ueda, Hitoshi; Kajikawa, Mariko; Ortel, Thomas L; Becker, Richard C 2012. Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitor. Thrombosis and haemostasis, 108 6, 1180-91

Chan, Mark Y; Tan, Karen; Tan, Huay-Cheem; Huan, Pei-Tee; Li, Bei; Phua, Qian-Hui; Lee, Hong-Kai; Lee, Chi-Hang; Low, Adrian; Becker, Richard C; Ong, Wen-Chong; Richards, Mark A; Salim, Agus; Tai, E-Shyong; Koay, Evelyn 2012. CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects. Pharmacogenomics, 13 5, 533-42

Hankey, Graeme J; Patel, Manesh R; Stevens, Susanna R; Becker, Richard C; Breithardt, Günter; Carolei, Antonio; Diener, Hans-Christoph; Donnan, Geoffrey A; Halperin, Jonathan L; Mahaffey, Kenneth W; Mas, Jean-Louis; Massaro, Ayrton; Norrving, Bo; Nessel, Christopher C; Paolini, John F; Roine, Risto O; Singer, Daniel E; Wong, Lawrence; Califf, Robert M; Fox, Keith A A; Hacke, Werner 2012. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. Lancet neurology, 11 4, 315-22

Husted, Steen; James, Stefan; Becker, Richard C; Horrow, Jay; Katus, Hugo; Storey, Robert F; Cannon, Christopher P; Heras, Magda; Lopes, Renato D; Morais, Joao; Mahaffey, Kenneth W; Bach, Richard G; Wojdyla, Daniel; Wallentin, Lars 2012. Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial. Circulation. Cardiovascular quality and outcomes, 5 5, 680-8

Nimjee, Shahid M; Lohrmann, Jens D; Wang, Haichen; Snyder, David J; Cummings, Thomas J; Becker, Richard C; Oney, Sabah; Sullenger, Bruce A 2012. Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor. Molecular therapy : the journal of the American Society of Gene Therapy, 20 2, 391-7

Rowley, Jesse W; Finn, Aloke V; French, Patricia A; Jennings, Lisa K; Bluestein, Danny; Gross, Peter L; Freedman, Jane E; Steinhubl, Steven R; Zimmerman, Guy A; Becker, Richard C; Dauerman, Harold L; Smyth, Susan S 2012. Cardiovascular devices and platelet interactions: understanding the role of injury, flow, and cellular responses. Circulation. Cardiovascular interventions, 5 2, 296-304

Wisler, James W; Becker, Richard C 2012. A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation. Critical pathways in cardiology, 11 2, 55-61

Wisler, James W; Becker, Richard C 2012. Oral factor Xa inhibitors for the long-term management of ACS. Nature reviews. Cardiology, 9 7, 392-401

Wisler, James W; Washam, Jeffrey B; Becker, Richard C 2012. Evaluation of dose requirements for prolonged bivalirudin administration in patients with renal insufficiency and suspected heparin-induced thrombocytopenia. Journal of thrombosis and thrombolysis, 33 3, 287-95

Ahmad, Tariq; Voora, Deepak; Becker, Richard C 2011. The pharmacogenetics of antiplatelet agents: towards personalized therapy? Nature reviews. Cardiology, 8 10, 560-71

Becker, Richard C 2011. Early-onset obesity and the unwanted promise of thrombosis. Journal of thrombosis and thrombolysis, 32 1, 125-8

Faxon, David P; Eikelboom, John W; Berger, Peter B; Holmes, David R; Bhatt, Deepak L; Moliterno, David J; Becker, Richard C; Angiolillo, Dominick J 2011. Consensus document: antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting. A North-American perspective. Thrombosis and haemostasis, 106 4, 572-84

Fox, Keith A A; Piccini, Jonathan P; Wojdyla, Daniel; Becker, Richard C; Halperin, Jonathan L; Nessel, Christopher C; Paolini, John F; Hankey, Graeme J; Mahaffey, Kenneth W; Patel, Manesh R; Singer, Daniel E; Califf, Robert M 2011. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. European heart journal, 32 19, 2387-94

Held, Claes; Asenblad, Nils; Bassand, Jean Pierre; Becker, Richard C; Cannon, Christopher P; Claeys, Marc J; Harrington, Robert A; Horrow, Jay; Husted, Steen; James, Stefan K; Mahaffey, Kenneth W; Nicolau, José C; Scirica, Benjamin M; Storey, Robert F; Vintila, Marius; Ycas, Joseph; Wallentin, Lars 2011. Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial. Journal of the American College of Cardiology, 57 6, 672-84

Lopes, Renato D; Becker, Richard C; Alexander, John H; Armstrong, Paul W; Califf, Robert M; Chan, Mark Y; Crowther, Mark; Granger, Christopher B; Harrington, Robert A; Hylek, Elaine M; James, Stefan K; Jolicoeur, E Marc; Mahaffey, Kenneth W; Newby, L Kristin; Peterson, Eric D; Pieper, Karen S; Van de Werf, Frans; Wallentin, Lars; White, Harvey D; Carvalho, Antonio C; Giraldez, Roberto R; Guimaraes, Helio P; Nader, Helena B; Kalil, Renato A K; Bizzachi, Joyce M A; Lopes, Antonio C; Garcia, David A 2011. Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil. Journal of thrombosis and thrombolysis, 32 2, 242-66

Povsic, Thomas J; Cohen, Mauricio G; Mehran, Roxana; Buller, Christopher E; Bode, Christoph; Cornel, Jan H; Kasprzak, Jaros?aw D; Montalescot, Gilles; Joseph, Diane; Wargin, William A; Rusconi, Christopher P; Zelenkofske, Steven L; Becker, Richard C; Alexander, John H 2011. A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: design and rationale of the RADAR Phase IIb trial. American heart journal, 161 2, 261-268.e1-2

Povsic, Thomas J; Wargin, William A; Alexander, John H; Krasnow, Joshua; Krolick, Merill; Cohen, Mauricio G; Mehran, Roxana; Buller, Christopher E; Bode, Christoph; Zelenkofske, Steven L; Rusconi, Christopher P; Becker, Richard C 2011. Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy. European heart journal, 32 19, 2412-9

Storey, Robert F; Becker, Richard C; Harrington, Robert A; Husted, Steen; James, Stefan K; Cools, Frank; Steg, Philippe Gabriel; Khurmi, Nardev S; Emanuelsson, Håkan; Cooper, Anna; Cairns, Richard; Cannon, Christopher P; Wallentin, Lars 2011. Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. European heart journal, 32 23, 2945-53

Storey, Robert F; Becker, Richard C; Harrington, Robert A; Husted, Steen; James, Stefan K; Cools, Frank; Steg, Philippe Gabriel; Khurmi, Nardev S; Emanuelsson, Hakan; Lim, Soo Teik; Cannon, Christopher P; Katus, Hugo A; Wallentin, Lars 2011. Pulmonary function in patients with acute coronary syndrome treated with ticagrelor or clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] pulmonary function substudy). The American journal of cardiology, 108 11, 1542-6

Woodruff, Rebecca S; Sullenger, Bruce; Becker, Richard C 2011. The many faces of the contact pathway and their role in thrombosis. Journal of thrombosis and thrombolysis, 32 1, 9-20

Xu, Weixian; Wang, Tracy Y; Becker, Richard C 2011. Hematologic diseases: from within the heart. Revista española de cardiología (English ed.), 64 7, 606-13

Becker, Richard C; Gurbel, Paul A 2010. Platelet P2Y12 receptor antagonist pharmacokinetics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies. Thrombosis and haemostasis, 103 3, 535-44

Brummett, Beverly H; Boyle, Stephen H; Ortel, Thomas L; Becker, Richard C; Siegler, Ilene C; Williams, Redford B 2010. Associations of depressive symptoms, trait hostility, and gender with C-reactive protein and interleukin-6 response after emotion recall. Psychosomatic medicine, 72 4, 333-9

Cannon, Christopher P; Harrington, Robert A; James, Stefan; Ardissino, Diego; Becker, Richard C; Emanuelsson, Håkan; Husted, Steen; Katus, Hugo; Keltai, Matyas; Khurmi, Nardev S; Kontny, Frederic; Lewis, Basil S; Steg, Philippe Gabriel; Storey, Robert F; Wojdyla, Daniel; Wallentin, Lars 2010. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study. Lancet, 375 9711, 283-93

Chan, Mark Y; Becker, Richard C; Sim, Ling-Ling; Tan, Virlynn; Lee, Chi-Hang; Low, Adrian F H; Teo, Swee-Guan; Ng, Kheng-Siang; Tan, Huay-Cheem; Yeo, Tiong-Cheng 2010. Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function. Annals of the Academy of Medicine, Singapore, 39 3, 179-84

Cohen, Mauricio G; Purdy, Drew A; Rossi, Joseph S; Grinfeld, Liliana R; Myles, Shelley K; Aberle, Laura H; Greenbaum, Adam B; Fry, Edward; Chan, Mark Y; Tonkens, Ross M; Zelenkofske, Steven; Alexander, John H; Harrington, Robert A; Rusconi, Christopher P; Becker, Richard C 2010. First clinical application of an actively reversible direct factor IXa inhibitor as an anticoagulation strategy in patients undergoing percutaneous coronary intervention. Circulation, 122 6, 614-22

Katz, Jason N; Shah, Bimal R; Volz, Elizabeth M; Horton, John R; Shaw, Linda K; Newby, L Kristin; Granger, Christopher B; Mark, Daniel B; Califf, Robert M; Becker, Richard C 2010. Evolution of the coronary care unit: clinical characteristics and temporal trends in healthcare delivery and outcomes. Critical care medicine, 38 2, 375-81

Krishnan, Anandi; Lopes, Renato D; Alexander, John H; Becker, Richard C; Goldstein, Larry B 2010. Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician. Journal of thrombosis and thrombolysis, 29 3, 368-77

Lopes, Renato D; Garcia, David; Becker, Richard C; Granger, Christopher B; Newby, L Kristin; Alexander, John H; Jolicoeur, E Marc; Handler, Allison; Pieper, Karen S; Carvalho, Antonio C; Guimaraes, Helio P; Chamone, Dalton A F; Baruzzi, Antonio C; Machado, Fabio S; Timerman, Ari; Lopes, Antonio C 2010. Highlights from the II International Symposium of Thrombosis and Anticoagulation (ISTA), October 22-23, 2009, São Paulo, Brazil. Journal of thrombosis and thrombolysis, 29 4, 395-408

Mackman, Nigel; Becker, Richard C 2010. DVT: a new era in anticoagulant therapy. Arteriosclerosis, thrombosis, and vascular biology, 30 3, 369-71

Povsic, Thomas J; Sullenger, Bruce A; Zelenkofske, Steven L; Rusconi, Christopher P; Becker, Richard C 2010. Translating nucleic acid aptamers to antithrombotic drugs in cardiovascular medicine. Journal of cardiovascular translational research, 3 6, 704-16

Rao, Sunil V; Melloni, Chiara; Myles-Dimauro, Shelley; Broderick, Samuel; Kosinski, Andrzej S; Kleiman, Neal S; Dzavík, Vladimír; Tanguay, Jean Francois; Chandna, Harish; Gammon, Roger; Rivera, Ernesto; Alexander, John H; Fier, Ian; Roach, James; Becker, Richard C 2010. Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial. Circulation, 121 15, 1713-21

Steg, Philippe Gabriel; James, Stefan; Harrington, Robert A; Ardissino, Diego; Becker, Richard C; Cannon, Christopher P; Emanuelsson, Håkan; Finkelstein, Ariel; Husted, Steen; Katus, Hugo; Kilhamn, Jan; Olofsson, Sylvia; Storey, Robert F; Weaver, W Douglas; Wallentin, Lars 2010. Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation, 122 21, 2131-41

Wallentin, Lars; James, Stefan; Storey, Robert F; Armstrong, Martin; Barratt, Bryan J; Horrow, Jay; Husted, Steen; Katus, Hugo; Steg, P Gabriel; Shah, Svati H; Becker, Richard C 2010. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet, 376 9749, 1320-8

Williams, Marlene S; Weiss, Ethan J; Sabatine, Marc S; Simon, Daniel I; Bahou, Wadie F; Becker, Lewis C; Parise, Leslie V; Dauerman, Harold L; French, Patricia A; Smyth, Susan S; Becker, Richard C 2010. Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. Arteriosclerosis, thrombosis, and vascular biology, 30 12, 2372-84

Woodruff, Becky; Sullenger, Bruce; Becker, Richard C 2010. Antithrombotic therapy in acute coronary syndrome: how far up the coagulation cascade will we go? Current cardiology reports, 12 4, 315-20

Becker, Richard C; Chan, Mark Y 2009. REG-1, a regimen comprising RB-006, a Factor IXa antagonist, and its oligonucleotide active control agent RB-007 for the potential treatment of arterial thrombosis. Current opinion in molecular therapeutics, 11 6, 707-15

Becker, Richard C; Scheiman, James; Dauerman, Harold L; Spencer, Frederick; Rao, Sunil; Sabatine, Marc; Johnson, David A; Chan, Frances; Abraham, Neena S; Quigley, Eamonn M M 2009. Management of platelet-directed pharmacotherapy in patients with atherosclerotic coronary artery disease undergoing elective endoscopic gastrointestinal procedures. The American journal of gastroenterology, 104 12, 2903-17

Berger, Jeffrey S; Elliott, Laine; Gallup, Dianne; Roe, Matthew; Granger, Christopher B; Armstrong, Paul W; Simes, R John; White, Harvey D; Van de Werf, Frans; Topol, Eric J; Hochman, Judith S; Newby, L Kristin; Harrington, Robert A; Califf, Robert M; Becker, Richard C; Douglas, Pamela S 2009. Sex differences in mortality following acute coronary syndromes. JAMA : the journal of the American Medical Association, 302 8, 874-82

Chan, Mark Y; Weitz, Jeffrey I; Merhi, Yahye; Harrington, Robert A; Becker, Richard C 2009. Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs. Journal of thrombosis and thrombolysis, 28 3, 366-80

Kiefer, Todd L; Becker, Richard C 2009. Inhibitors of platelet adhesion. Circulation, 120 24, 2488-95

Smyth, S S; McEver, R P; Weyrich, A S; Morrell, C N; Hoffman, M R; Arepally, G M; French, P A; Dauerman, H L; Becker, R C 2009. Platelet functions beyond hemostasis. Journal of thrombosis and haemostasis : JTH, 7 11, 1759-66

Smyth, Susan S; Woulfe, Donna S; Weitz, Jeffrey I; Gachet, Christian; Conley, Pamela B; Goodman, Shaun G; Roe, Matthew T; Kuliopulos, Athan; Moliterno, David J; French, Patricia A; Steinhubl, Steven R; Becker, Richard C 2009. G-protein-coupled receptors as signaling targets for antiplatelet therapy. Arteriosclerosis, thrombosis, and vascular biology, 29 4, 449-57

Wallentin, Lars; Becker, Richard C; Budaj, Andrzej; Cannon, Christopher P; Emanuelsson, Håkan; Held, Claes; Horrow, Jay; Husted, Steen; James, Stefan; Katus, Hugo; Mahaffey, Kenneth W; Scirica, Benjamin M; Skene, Allan; Steg, Philippe Gabriel; Storey, Robert F; Harrington, Robert A ; Freij, Anneli; Thorsén, Mona 2009. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. The New England journal of medicine, 361 11, 1045-57

Becker, Richard C; Sane, David 2008. Early career investigator's circle: identifying and nurturing the next generation of scientists and scientific writers. Journal of thrombosis and thrombolysis, 26 2, 165

Berger, Jeffrey S; Frye, Carla B; Harshaw, Qing; Edwards, Fred H; Steinhubl, Steven R; Becker, Richard C 2008. Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysis. Journal of the American College of Cardiology, 52 21, 1693-701

Chan, Mark Y; Becker, Richard C; Harrington, Robert A; Peterson, Eric D; Armstrong, Paul W; White, Harvey; Fox, Keith A A; Ohman, E Magnus; Roe, Matthew T 2008. Noninvasive, medical management for non-ST-elevation acute coronary syndromes. American heart journal, 155 3, 397-407

Douketis, James D; Berger, Peter B; Dunn, Andrew S; Jaffer, Amir K; Spyropoulos, Alex C; Becker, Richard C; Ansell, Jack 2008. The perioperative management of antithrombotic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest, 133 6 Suppl, 299S-339S

Lohrmann, Jens; Becker, Richard C 2008. New anticoagulants--the path from discovery to clinical practice. The New England journal of medicine, 358 26, 2827-9

Becker, Richard C 2007. Off-target properties of pharmacotherapy and the importance of mechanistic investigations in early clinical phase drug development. Journal of thrombosis and thrombolysis, 23 2, 159-61

Gurbel, Paul A; Becker, Richard C; Mann, Kenneth G; Steinhubl, Steven R; Michelson, Alan D 2007. Platelet function monitoring in patients with coronary artery disease. Journal of the American College of Cardiology, 50 19, 1822-34

Katz, Jason N; Turer, Aslan T; Becker, Richard C 2007. Cardiology and the critical care crisis: a perspective. Journal of the American College of Cardiology, 49 12, 1279-82

Dyke, Christopher K; Steinhubl, Steven R; Kleiman, Neal S; Cannon, Richard O; Aberle, Laura G; Lin, Min; Myles, Shelley K; Melloni, Chiara; Harrington, Robert A; Alexander, John H; Becker, Richard C; Rusconi, Christopher P 2006. First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Circulation, 114 23, 2490-7

Patel, Manesh R; Meine, Trip J; Lindblad, Lauren; Griffin, Jeffrey; Granger, Christopher B; Becker, Richard C; Van de Werf, Frans; White, Harvey; Califf, Robert M; Harrington, Robert A 2006. Cardiac tamponade in the fibrinolytic era: analysis of >100,000 patients with ST-segment elevation myocardial infarction. American heart journal, 151 2, 316-22

Krishnan, Ranjini; Becker, Richard J; Beighley, Lisa M; López-Candales, Angel 2005. Impact of body mass index on markers of left ventricular thickness and mass calculation: results of a pilot analysis. Echocardiography (Mount Kisco, N.Y.), 22 3, 203-10

Becker, Richard C; Alexander, John H; Li, Youfu; Robertson, Thomas; Kunitada, Satoshi; Spencer, Frederick A; Yang, Hongqiu; Harrington, Robert A 2004. Vascular endothelial tissue factor pathway inhibitor kinetics in culture following exposure to DX-9065a--a selective and direct factor Xa inhibitor. Journal of thrombosis and thrombolysis, 18 3, 193-7

Ali, Omar A; Okike, Nsidinanya; Hogan, Robert G; Becker, Richard C 2002. Intramural hematoma of the thoracic aorta in a woman with neurofibromatosis. The Annals of thoracic surgery, 73 3, 958-60

Becker, Richard C 2002. Choice of agents to limit the coagulation cascade in acute coronary syndromes. Current cardiology reports, 4 4, 272-7

Becker, Richard C; Spencer, Frederick A; Gibson, Michael; Rush, Janet E; Sanderink, Gerard; Murphy, Sabina A; Ball, Steven P; Antman, Elliott M 2002. Influence of patient characteristics and renal function on factor Xa inhibition pharmacokinetics and pharmacodynamics after enoxaparin administration in non-ST-segment elevation acute coronary syndromes. American heart journal, 143 5, 753-9

Becker, Richard; Smith, Marion; Maier, Jerry 2002. 1Q[3a]. Are hospitals focusing enough on disaster readiness? Hospitals & health networks / AHA, 76 7, 30

Bonow, Robert O; Mitch, William E; Nesto, Richard W; O'Gara, Patrick T; Becker, Richard C; Clark, Luther T; Hunt, Sharon; Jialal, Ishwarlal; Lipshultz, Stephen E; Loh, Evan 2002. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group V: management of cardiovascular-renal complications. Circulation, 105 18, e159-64

Dyke, Christopher K; Becker, Richard C; Kleiman, Neal S; Hochman, Judith S; Bovill, Edwin G; Lincoff, A Michael; Gerstenblith, Gary; Dzavik, Vladimir; Gardner, Laura H; Hasselblad, Vic; Zillman, Linda A; Shimoto, Yoshimasa; Robertson, Thomas L; Kunitada, Satoshi; Armstrong, Paul W; Harrington, Robert A 2002. First experience with direct factor Xa inhibition in patients with stable coronary disease: a pharmacokinetic and pharmacodynamic evaluation. Circulation, 105 20, 2385-91

Harrold, Leslie R; Gurwitz, Jerry H; Tate, Janet P; Becker, Richard; Stuart, Tammy; Elwell, Anne; Radford, Martha 2002. Physician attitudes concerning anticoagulation services in the long-term care setting. Journal of thrombosis and thrombolysis, 14 1, 59-64

Li, You Fu; Spencer, Frederick A; Becker, Richard C 2002. Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa receptor-directed platelet inhibition. American heart journal, 143 4, 725-32

Becker, Richard C.; Spencer, Frederick A. 2001. Moving Up the Coagulation Cascade: Potential Factor X Inhibition for Percutaneous Coronary Intervention. Current interventional cardiology reports, 3 3, 251-259

Boyle, Stephen H; Samad, Zainab; Becker, Richard C; Williams, Redford; Kuhn, Cynthia; Ortel, Thomas L; Kuchibhatla, Maragatha; Prybol, Kevin; Rogers, Joseph; O'Connor, Christopher; Velazquez, Eric J; Jiang, Wei . Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease. Psychosomatic medicine, 75 9, 822-31