Education/CredentialsFellowship: Yale University School of Medicine (Nephrology)Residency: Shiraz University School of Medicine (Internal Medicine)Medical Degree: Shiraz University School of Medicine Board Certifications & LicensesAmerican Board of Internal Medicine (Certification Date: 2000-08-22) - (Recertification Date: 2010-12-31)American Board of Internal Medicine (Nephrology) (Certification Date: 2018-10-03) Contact Information Email soleimm@ucmail.uc.edu Research InterestsIdentification, Cloning and Examination of Genes Regulating Acid Base Transport in the Kidney, Salt Absorption in the Kidney Distal Nephron and Blood Pressure Regulation Through the Generation and Examination of Transgenic Mice, Identification and Examination of Genes that Play Important Roles in Either Promoting or Protecting Against Tissue Injury in Kidney Damage Clinical Interests Nephrology Peer Reviewed Publications Amlal H, Xu J, Barone S, Zahedi K, Soleimani M 2013. The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion J Molec Med, 91 5, 561-572Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M 2013. Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects of bicarbonate absoprtion and ammonium excretion J Mol Med, , Soleimani M 2013. SLC26 Cl-HCO3- exchangers in the kidneys: roles in health and disease Kidney International, , Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall M 2012. SLC26A9-mediated chloride secretion prevents mucus obstruction in airwar inflammation J Clin Invest, , Li HC, Kucher V, Li EY, Conforti L, Zahedi K, Soleimani M 2012. The role of aspartic acid residues 405 and 416 of the kidney isotope od sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane Am J Physiol Cell Physiol, 302 12, C1713-C1730Soleimani S, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H 2012. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure Proc Natl Acad Sci U S A, 109 33, 13368-13373Zahedi K, Barone S, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Caero RA Jr, Soleimani M 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CC14-induced acute liver injury Am J Physiol: Gastrointestinal Liver Physiol, 303 5, G546-G560Xu J, Barone S, Li H, Holiday S, Zahedi K, Soleimani M 2011. Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney Kindey Int, 80 9, 926-937Amlal H, Petrovic S, Xu J, Wang Z, Sun X, Barone S, Soleimani M 2010. Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct Am J Physiol Cell Physiol, 299 1, C33-C41Barone S, Fussell SL, SIngh AK, Lucas F, Xu J, Kim C, Wu X, Yu Y, Amlal H, Seidler U, Zuo J, Soleimani M 2009. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension J Biol Chem, 287 , 2056-5066Li HC, Collier JH, Shawki A, Rudra JS, Li EY, Mackenzie B, Soleimani M 2009. Sequence- or position-specific mutations in the carboxyl terminal FL motif of the kidney sodium bicarbonate cotransporter (NBCI) disrupt its basolateral targeting and alpha-helical structure J Membr Biol, 228 , 111-124Xu J, Song P, Nakamura S, Miller M, Barone S, Alper SL, Riederer B, Bonhagen J, Arend LJ, Amlal H, Seidler U, Soleimani M 2009. Deletion of the chloride transporter Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion J Biol Chem, 282 , 29470-29479Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfield J, Seidler U, Soleimani M 2008. Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach Proc Natl Acad Sci USA, 105 , 17955-17960Rahmati N, Kunzelmann K, Kongsuphol P, Xu J, barone S, De Zeeuw C, Soleimani M . Slc26a11 is a Chloride Channel in the Brain: Expression in Purkinje Cells and Stimulatin of V H+-ATPase Pflugers Archive, ,
Research InterestsIdentification, Cloning and Examination of Genes Regulating Acid Base Transport in the Kidney, Salt Absorption in the Kidney Distal Nephron and Blood Pressure Regulation Through the Generation and Examination of Transgenic Mice, Identification and Examination of Genes that Play Important Roles in Either Promoting or Protecting Against Tissue Injury in Kidney Damage
Peer Reviewed Publications Amlal H, Xu J, Barone S, Zahedi K, Soleimani M 2013. The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion J Molec Med, 91 5, 561-572Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M 2013. Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects of bicarbonate absoprtion and ammonium excretion J Mol Med, , Soleimani M 2013. SLC26 Cl-HCO3- exchangers in the kidneys: roles in health and disease Kidney International, , Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall M 2012. SLC26A9-mediated chloride secretion prevents mucus obstruction in airwar inflammation J Clin Invest, , Li HC, Kucher V, Li EY, Conforti L, Zahedi K, Soleimani M 2012. The role of aspartic acid residues 405 and 416 of the kidney isotope od sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane Am J Physiol Cell Physiol, 302 12, C1713-C1730Soleimani S, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H 2012. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure Proc Natl Acad Sci U S A, 109 33, 13368-13373Zahedi K, Barone S, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Caero RA Jr, Soleimani M 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CC14-induced acute liver injury Am J Physiol: Gastrointestinal Liver Physiol, 303 5, G546-G560Xu J, Barone S, Li H, Holiday S, Zahedi K, Soleimani M 2011. Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney Kindey Int, 80 9, 926-937Amlal H, Petrovic S, Xu J, Wang Z, Sun X, Barone S, Soleimani M 2010. Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct Am J Physiol Cell Physiol, 299 1, C33-C41Barone S, Fussell SL, SIngh AK, Lucas F, Xu J, Kim C, Wu X, Yu Y, Amlal H, Seidler U, Zuo J, Soleimani M 2009. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension J Biol Chem, 287 , 2056-5066Li HC, Collier JH, Shawki A, Rudra JS, Li EY, Mackenzie B, Soleimani M 2009. Sequence- or position-specific mutations in the carboxyl terminal FL motif of the kidney sodium bicarbonate cotransporter (NBCI) disrupt its basolateral targeting and alpha-helical structure J Membr Biol, 228 , 111-124Xu J, Song P, Nakamura S, Miller M, Barone S, Alper SL, Riederer B, Bonhagen J, Arend LJ, Amlal H, Seidler U, Soleimani M 2009. Deletion of the chloride transporter Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion J Biol Chem, 282 , 29470-29479Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfield J, Seidler U, Soleimani M 2008. Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach Proc Natl Acad Sci USA, 105 , 17955-17960Rahmati N, Kunzelmann K, Kongsuphol P, Xu J, barone S, De Zeeuw C, Soleimani M . Slc26a11 is a Chloride Channel in the Brain: Expression in Purkinje Cells and Stimulatin of V H+-ATPase Pflugers Archive, ,
Amlal H, Xu J, Barone S, Zahedi K, Soleimani M 2013. The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion J Molec Med, 91 5, 561-572Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M 2013. Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects of bicarbonate absoprtion and ammonium excretion J Mol Med, , Soleimani M 2013. SLC26 Cl-HCO3- exchangers in the kidneys: roles in health and disease Kidney International, , Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall M 2012. SLC26A9-mediated chloride secretion prevents mucus obstruction in airwar inflammation J Clin Invest, , Li HC, Kucher V, Li EY, Conforti L, Zahedi K, Soleimani M 2012. The role of aspartic acid residues 405 and 416 of the kidney isotope od sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane Am J Physiol Cell Physiol, 302 12, C1713-C1730Soleimani S, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H 2012. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure Proc Natl Acad Sci U S A, 109 33, 13368-13373Zahedi K, Barone S, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Caero RA Jr, Soleimani M 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CC14-induced acute liver injury Am J Physiol: Gastrointestinal Liver Physiol, 303 5, G546-G560Xu J, Barone S, Li H, Holiday S, Zahedi K, Soleimani M 2011. Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney Kindey Int, 80 9, 926-937Amlal H, Petrovic S, Xu J, Wang Z, Sun X, Barone S, Soleimani M 2010. Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct Am J Physiol Cell Physiol, 299 1, C33-C41Barone S, Fussell SL, SIngh AK, Lucas F, Xu J, Kim C, Wu X, Yu Y, Amlal H, Seidler U, Zuo J, Soleimani M 2009. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension J Biol Chem, 287 , 2056-5066Li HC, Collier JH, Shawki A, Rudra JS, Li EY, Mackenzie B, Soleimani M 2009. Sequence- or position-specific mutations in the carboxyl terminal FL motif of the kidney sodium bicarbonate cotransporter (NBCI) disrupt its basolateral targeting and alpha-helical structure J Membr Biol, 228 , 111-124Xu J, Song P, Nakamura S, Miller M, Barone S, Alper SL, Riederer B, Bonhagen J, Arend LJ, Amlal H, Seidler U, Soleimani M 2009. Deletion of the chloride transporter Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion J Biol Chem, 282 , 29470-29479Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfield J, Seidler U, Soleimani M 2008. Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach Proc Natl Acad Sci USA, 105 , 17955-17960Rahmati N, Kunzelmann K, Kongsuphol P, Xu J, barone S, De Zeeuw C, Soleimani M . Slc26a11 is a Chloride Channel in the Brain: Expression in Purkinje Cells and Stimulatin of V H+-ATPase Pflugers Archive, ,