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Department of

Environmental Health

Shuk-Mei Ho, PhD

Jacob G. Schmidlapp Professor and Chair of Environmental Health and Director of the Cincinnati Cancer Center

Education/Credentials
  • Bachelor's Degree: University of Hong Kong
  • Doctoral Degree: University of Hong Kong

Contact Information
  • Kettering Laboratory Room 130
  • 160 Panzeca Way
  • Cincinnati, Ohio 45267
  • Office 513-558-5701
  • Fax 513-558-0071
  • Email shuk-mei.ho@uc.edu

Peer Reviewed Publications

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Govindarajah, V., Leung, Y., Ying, J., Gear, R., Bornschein, R. L., Medvedovic, M., & Ho, S. 2016. In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands. The Journal of Nutritional Biochemistry, 29 , 73-82

Lam, H., Ho, S., Chen, J., Medvedovic, M., & Tam, N. N. C. 2016. Bisphenol A Disrupts HNF4?-Regulated Gene Networks Linking to Prostate Preneoplasia and Immune Disruption in Noble Rats. Endocrinology, 157 1, 207-19

Miller, M., Bailey, B., Govindarajah, V., Levin, L., Metzger, T., Pinney, S. M., Leung, Y., & Ho, S. 2016. A community survey on knowledge of the impact of environmental and epigenetic factors on health and disease. Perspectives in Public Health, ,

Schade, G. R., Holt, S., Zhang, X., Song, D., Wright, J. L., Zhao, S., Kolb, S., Lam, H., Levin, L., Leung, Y., Ho, S., & Stanford, J. L. 2016. Prostate Cancer Expression Profiles of Cytoplasmic ER?1 and Nuclear ER?2 Are Associated with Poor Outcomes following Radical Prostatectomy. The Journal of Urology, ,

Seachrist, D. D., Bonk, K. W., Ho, S., Prins, G. S., Soto, A. M., & Keri, R. A. 2016. A review of the carcinogenic potential of bisphenol A. Reproductive Toxicology (Elmsford, N.Y.), 59 , 167-82

Ho, S., Cheong, A., Lam, H., Hu, W., Shi, G., Zhu, X., Chen, J., Zhang, X., Medvedovic, M., Leung, Y., & Prins, G. S. 2015. Exposure of Human Prostaspheres to Bisphenol A Epigenetically Regulates SNORD Family Noncoding RNAs via Histone Modification. Endocrinology, 156 11, 3984-95

Ho, S., & Tam, N. N. C. 2015. Organoid model shows effect of BPA on prostate development. Nature Reviews. Urology, 12 12, 658-9

Martinez, A. M., Cheong, A., Ying, J., Xue, J., Kannan, K., Leung, Y., Thomas, M. A., & Ho, S. 2015. Effects of High-Butterfat Diet on Embryo Implantation in Female Rats Exposed to Bisphenol A. Biology of Reproduction, 93 6, 147

Panchanathan, R., Liu, H., Leung, Y., Ho, S., & Choubey, D. 2015. Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells. Molecular and Cellular Endocrinology, 415 , 45-55

Paquette, I. M., Ying, J., Shah, S. A., Abbott, D. E., & Ho, S. 2015. African Americans should be screened at an earlier age for colorectal cancer. Gastrointestinal Endoscopy, 82 5, 878-83

Tam, N. N., Zhang, X., Xiao, H., Song, D., Levin, L., Meller, J., & Ho, S. 2015. Increased susceptibility of estrogen-induced bladder outlet obstruction in a novel mouse model. Laboratory Investigation; A Journal of Technical Methods and Pathology, 95 5, 546-60

Warzak, D. A., Johnson, S. A., Ellersieck, M. R., Roberts, R. M., Zhang, X., Ho, S., & Rosenfeld, C. S. 2015. Effects of post-weaning diet on metabolic parameters and DNA methylation status of the cryptic promoter in the A(vy) allele of viable yellow mice. The Journal of Nutritional Biochemistry, 26 6, 667-74

Wong, R. L. Y., Wang, Q., Treviño, L. S., Bosland, M. C., Chen, J., Medvedovic, M., Prins, G. S., Kannan, K., Ho, S., & Walker, C. L. 2015. Identification of secretaglobin Scgb2a1 as a target for developmental reprogramming by BPA in the rat prostate. Epigenetics, 10 2, 127-34

Yang, S., Giovannucci, E., Bracken, B., Ho, S., & Wu, T. 2015. Association between plasma fluorescent oxidation products and erectile dysfunction: A prospective study. BMC Urology, 15 , 85

Yang, S., Pinney, S. M., Mallick, P., Ho, S., Bracken, B., & Wu, T. 2015. Impact of Oxidative Stress Biomarkers and Carboxymethyllysine (an Advanced Glycation End Product) on Prostate Cancer: A Prospective Study. Clinical Genitourinary Cancer, 13 5, e347-51

Ho, Shuk-Mei 2014. Battle against the odds: win with effort, attitude, and perseverance! Endocrine-related Cancer, 21 4, P19-24

Knower, K. C., To, S. Q., Leung, Y., Ho, S., & Clyne, C. D. 2014. Endocrine disruption of the epigenome: a breast cancer link. Endocrine-related Cancer, 21 2, T33-55

Lam, H., Ouyang, B., Chen, J., Ying, J., Wang, J., Wu, C., Jia, L., Medvedovic, M., Vessella, R. L., & Ho, S. 2014. Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer. Endocrine-related Cancer, 21 6, 903-14

Langevin, S. M., Pinney, S. M., Leung, Y., & Ho, S. 2014. Does epigenetic drift contribute to age-related increases in breast cancer risk? Epigenomics, 6 4, 367-9

Leung, Y., Chan, Q. K., Ng, C., Ma, F. M., Tse, H., To, K., Maranchie, J., Ho, S., & Lau, K. 2014. Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer. PloS One, 9 5, e98037

Prins, G. S., Hu, W., Shi, G., Hu, D., Majumdar, S., Li, G., Huang, K., Nelles, J. L., Ho, S., Walker, C. L., Kajdacsy-Balla, A., & van Breemen, R. B. 2014. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology, 155 3, 805-17

Tarapore, P., Ying, J., Ouyang, B., Burke, B., Bracken, B., & Ho, S. 2014. Exposure to bisphenol A correlates with early-onset prostate cancer and promotes centrosome amplification and anchorage-independent growth in vitro. PloS One, 9 3, e90332

Yang, W. S., Chadalapaka, G., Cho, S., Lee, S., Jin, U., Jutooru, I., Choi, K., Leung, Y., Ho, S., Safe, S., & Kim, K. 2014. The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis. Neoplasia (New York, N.Y.), 16 12, 1059-69

Brunst, K. J., Leung, Y., Ryan, P. H., Khurana Hershey, G. K., Levin, L., Ji, H., Lemasters, G. K., & Ho, S. 2013. Forkhead box protein 3 (FOXP3) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma. The Journal of Allergy and Clinical Immunology, 131 2, 592-4.e1-3

Chen, A., Park, J., Linderholm, L., Rhee, A., Petreas, M., DeFranco, E. A., Dietrich, K. N., & Ho, S. 2013. Hydroxylated polybrominated diphenyl ethers in paired maternal and cord sera. Environmental Science & Technology, 47 8, 3902-8

Chu, S., Zhang, H., Maher, C., McDonald, J. D., Zhang, X., Ho, S., Yan, B., Chillrud, S., Perera, F., Factor, P., & Miller, R. L. 2013. Prenatal and postnatal polycyclic aromatic hydrocarbon exposure, airway hyperreactivity, and Beta-2 adrenergic receptor function in sensitized mouse offspring. Journal of Toxicology, 2013 , 603581

Jin, C., Chen, J., Meng, Q., Carreira, V., Tam, N. N. C., Geh, E., Karyala, S., Ho, S., Zhou, X., Medvedovic, M., & Xia, Y. 2013. Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Developmental Biology, 374 1, 96-107

Lee, M., Ho, S., Tarapore, P., Chung, I., & Leung, Y. 2013. Estrogen receptor ? isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12. Neoplasia (New York, N.Y.), 15 11, 1262-71

Lee, M., Leung, Y., Chung, I., Tarapore, P., & Ho, S. 2013. Estrogen receptor ? (ER?1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent manner. The Journal of Biological Chemistry, 288 35, 25038-52

Lee, M., Ouyang, B., Ho, S., & Leung, Y. 2013. Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation. Molecular and Cellular Endocrinology, 376 1-2, 125-35

Ouyang, B., Bernstein, D. I., Lummus, Z. L., Ying, J., Boulet, L., Cartier, A., Gautrin, D., & Ho, S. 2013. Interferon-? promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma. Toxicological Sciences : An Official Journal of the Society of Toxicology, 133 2, 218-24

Smithrud, D. B., Wang, X., Tarapore, P., & Ho, S. 2013. Crown Ether Host-Rotaxanes as Cytotoxic Agents. ACS Medicinal Chemistry Letters, 4 1, 27-31

Wu, T., Wang, Y., Ho, S., & Giovannucci, E. 2013. Plasma levels of nitrate and risk of prostate cancer: a prospective study. Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology, 22 7, 1210-8

Greathouse, K. L., Bredfeldt, T., Everitt, J. I., Lin, K., Berry, T., Kannan, K., Mittelstadt, M. L., Ho, S., & Walker, C. L. 2012. Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. Molecular Cancer Research : MCR, 10 4, 546-57

Ho, S., Johnson, A., Tarapore, P., Janakiram, V., Zhang, X., & Leung, Y. 2012. Environmental epigenetics and its implication on disease risk and health outcomes. ILAR Journal / National Research Council, Institute of Laboratory Animal Resources, 53 3-4, 289-305

Isaac, J., Tarapore, P., Zhang, X., Lam, Y., & Ho, S. 2012. Site-specific S-nitrosylation of integrin ?6 increases the extent of prostate cancer cell migration by enhancing integrin ?1 association and weakening adherence to laminin-1. Biochemistry, 51 48, 9689-97

Lam, H., Suresh Babu, C. V., Wang, J., Yuan, Y., Lam, Y., Ho, S., & Leung, Y. 2012. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion. Molecular and Cellular Endocrinology, 358 1, 27-35

Leung, Y., Lee, M., Lam, H., Tarapore, P., & Ho, S. 2012. Estrogen receptor-beta and breast cancer: translating biology into clinical practice. Steroids, 77 7, 727-37

Ouyang, B., Baxter, C. S., Lam, H., Yeramaneni, S., Levin, L., Haynes, E., & Ho, S. 2012. Hypomethylation of dual specificity phosphatase 22 promoter correlates with duration of service in firefighters and is inducible by low-dose benzo[a]pyrene. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine, 54 7, 774-80

Privette Vinnedge, L. M., Ho, S., Wikenheiser-Brokamp, K. A., & Wells, S. I. 2012. The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer. PloS One, 7 10, e46985

Tang, W., Levin, L., Talaska, G., Cheung, Y. Y., Herbstman, J., Tang, D., Miller, R. L., Perera, F., & Ho, S. 2012. Maternal exposure to polycyclic aromatic hydrocarbons and 5'-CpG methylation of interferon-? in cord white blood cells. Environmental Health Perspectives, 120 8, 1195-200

Tang, W., Morey, L. M., Cheung, Y. Y., Birch, L., Prins, G. S., & Ho, S. 2012. Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life. Endocrinology, 153 1, 42-55

Walker, C. L., & Ho, S. 2012. Developmental reprogramming of cancer susceptibility. Nature Reviews. Cancer, 12 7, 479-86

Chen, A., Dietrich, K. N., Huo, X., & Ho, S. 2011. Developmental neurotoxicants in e-waste: an emerging health concern. Environmental Health Perspectives, 119 4, 431-8

Ho, S., Lee, M., Lam, H., & Leung, Y. 2011. Estrogens and prostate cancer: etiology, mediators, prevention, and management. Endocrinology and Metabolism Clinics of North America, 40 3, 591-614, ix

Howard, T. D., Ho, S., Zhang, L., Chen, J., Cui, W., Slager, R., Gray, S., Hawkins, G. A., Medvedovic, M., & Wagner, J. D. 2011. Epigenetic changes with dietary soy in cynomolgus monkeys. PloS One, 6 10, e26791

Hu, W., Shi, G., Lam, H., Hu, D., Ho, S., Madueke, I. C., Kajdacsy-Balla, A., & Prins, G. S. 2011. Estrogen-initiated transformation of prostate epithelium derived from normal human prostate stem-progenitor cells. Endocrinology, 152 6, 2150-63

Leung, Y., & Ho, S. 2011. Estrogen receptor ?: switching to a new partner and escaping from estrogen. Science Signaling, 4 168, pe19

Ouyang, B., Leung, Y., Wang, V., Chung, E., Levin, L., Bracken, B., Cheng, L., & Ho, S. 2011. ?-Methylacyl-CoA racemase spliced variants and their expression in normal and malignant prostate tissues. Urology, 77 1, 249.e1-7

Prins, G. S., Ye, S., Birch, L., Ho, S., & Kannan, K. 2011. Serum bisphenol A pharmacokinetics and prostate neoplastic responses following oral and subcutaneous exposures in neonatal Sprague-Dawley rats. Reproductive Toxicology (Elmsford, N.Y.), 31 1, 1-9

Tarapore, P., Shu, Y., Guo, P., & Ho, S. 2011. Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancers. Molecular Therapy : the Journal of the American Society of Gene Therapy, 19 2, 386-94

Zhang, X., & Ho, S. 2011. Epigenetics meets endocrinology. Journal of Molecular Endocrinology, 46 1, R11-32

Zhou, Q., Ching, A. K., Leung, W. K., Szeto, C. Y., Ho, S., Chan, P. K., Yuan, Y., Lai, P. B., Yeo, W., & Wong, N. 2011. Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma. International Journal of Oncology, 38 3, 721-31

Ho, Shuk-Mei 2010. Environmental epigenetics of asthma: an update. The Journal of Allergy and Clinical Immunology, 126 3, 453-65

Joseph, D., Ho, S., & Syed, V. 2010. Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer. Molecular Cancer Therapeutics, 9 2, 499-509

Lam, Y. W., Yuan, Y., Isaac, J., Babu, C. V. S., Meller, J., & Ho, S. 2010. Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells. PloS One, 5 2, e9075

Leung, Y., Lam, H., Wu, S., Song, D., Levin, L., Cheng, L., Wu, C., & Ho, S. 2010. Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion. Endocrine-related Cancer, 17 3, 675-89

Panchanathan, R., Shen, H., Zhang, X., Ho, S., & Choubey, D. 2010. Mutually positive regulatory feedback loop between interferons and estrogen receptor-alpha in mice: implications for sex bias in autoimmunity. PloS One, 5 5, e10868

Prins, G. S., & Ho, S. 2010. Early-life estrogens and prostate cancer in an animal model. Journal of Developmental Origins of Health and Disease, 1 6, 365-70

Tam, N. N. C., Szeto, C. Y. Y., Freudenberg, J. M., Fullenkamp, A. N., Medvedovic, M., & Ho, S. 2010. Research resource: estrogen-driven prolactin-mediated gene-expression networks in hormone-induced prostatic intraepithelial neoplasia. Molecular Endocrinology (Baltimore, Md.), 24 11, 2207-17

Curran, C. P., Park, R. M., Ho, S., & Haynes, E. N. 2009. Incorporating genetics and genomics in risk assessment for inhaled manganese: from data to policy. Neurotoxicology, 30 5, 754-60

Marston, D. A., McElhinney, L. M., Ali, Y. H., Intisar, K. S., Ho, S. M., Freuling, C., Müller, T., & Fooks, A. R. 2009. Phylogenetic analysis of rabies viruses from Sudan provides evidence of a viral clade with a unique molecular signature. Virus Research, 145 2, 244-50

Myers, J. P., vom Saal, F. S., Akingbemi, B. T., Arizono, K., Belcher, S., Colborn, T., Chahoud, I., Crain, D. A., Farabollini, F., Guillette, L. J., Hassold, T., Ho, S., Hunt, P. A., Iguchi, T., Jobling, S., Kanno, J., Laufer, H., Marcus, M., McLachlan, J. A., Nadal, A., Oehlmann, J., Olea, N., Palanza, P., Parmigiani, S., Rubin, B. S., Schoenfelder, G., Sonnenschein, C., Soto, A. M., Talsness, C. E., Taylor, J. A., Vandenberg, L. N., Vandenbergh, J. G., Vogel, S., Watson, C. S., Welshons, W. V., & Zoeller, R. T. 2009. Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environmental Health Perspectives, 117 3, 309-15

Ouyang, B., Bracken, B., Burke, B., Chung, E., Liang, J., & Ho, S. 2009. A duplex quantitative polymerase chain reaction assay based on quantification of alpha-methylacyl-CoA racemase transcripts and prostate cancer antigen 3 in urine sediments improved diagnostic accuracy for prostate cancer. The Journal of Urology, 181 6, 2508-13; discussion

Perera, F., Tang, W., Herbstman, J., Tang, D., Levin, L., Miller, R., & Ho, S. 2009. Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PloS One, 4 2, e4488

Schiewer, M. J., Morey, L. M., Burd, C. J., Liu, Y., Merry, D. E., Ho, S., & Knudsen, K. E. 2009. Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer. Oncogene, 28 7, 1016-27

Xiong, S. D., Yu, K., Liu, X. H., Yin, L. H., Kirschenbaum, A., Yao, S., Narla, G., DiFeo, A., Wu, J. B., Yuan, Y., Ho, S., Lam, Y. W., & Levine, A. C. 2009. Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells. International Journal of Cancer, 125 4, 774-82

Zhang, X., Leav, I., Revelo, M. P., Deka, R., Medvedovic, M., Jiang, Z., & Ho, S. 2009. Deletion hotspots in AMACR promoter CpG island are cis-regulatory elements controlling the gene expression in the colon. PLoS Genetics, 5 1, e1000334

Bakshi, S., Zhang, X., Godoy-Tundidor, S., Cheng, R. Y. S., Sartor, M. A., Medvedovic, M., & Ho, S. 2008. Transcriptome analyses in normal prostate epithelial cells exposed to low-dose cadmium: oncogenic and immunomodulations involving the action of tumor necrosis factor. Environmental Health Perspectives, 116 6, 769-76

Choubey, D., Deka, R., & Ho, S. 2008. Interferon-inducible IFI16 protein in human cancers and autoimmune diseases. Frontiers in Bioscience : A Journal and Virtual Library, 13 , 598-608

Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, A., McLachlan, J. A., Schwartz, J., Skakkebaek, N., Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C., & Guillette, L. J. 2008. Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertility and Sterility, 90 4, 911-40

Lam, Y. W., Tam, N. N. C., Evans, J. E., Green, K. M., Zhang, X., & Ho, S. 2008. Differential proteomics in the aging Noble rat ventral prostate. Proteomics, 8 13, 2750-63

Miller, R. L., & Ho, S. 2008. Environmental epigenetics and asthma: current concepts and call for studies. American Journal of Respiratory and Critical Care Medicine, 177 6, 567-73

Prins, G. S., Tang, W., Belmonte, J., & Ho, S. 2008. Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis. Basic & Clinical Pharmacology & Toxicology, 102 2, 134-8

Prins, G. S., Tang, W., Belmonte, J., & Ho, S. 2008. Developmental exposure to bisphenol A increases prostate cancer susceptibility in adult rats: epigenetic mode of action is implicated. Fertility and Sterility, 89 2 Suppl, e41

Tam, N. N. C., Szeto, C. Y., Sartor, M. A., Medvedovic, M., & Ho, S. 2008. Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17beta-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats. Neoplasia (New York, N.Y.), 10 1, 20-40

Tam, N. N. C., & Ho, S. 2008. Culture of whole embryonic kidneys: present status and beyond. The Journal of Urology, 179 1, 17

Tang, W., Newbold, R., Mardilovich, K., Jefferson, W., Cheng, R. Y. S., Medvedovic, M., & Ho, S. 2008. Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology, 149 12, 5922-31

Alimirah, F., Panchanathan, R., Chen, J., Zhang, X., Ho, S., & Choubey, D. 2007. Expression of androgen receptor is negatively regulated by p53. Neoplasia (New York, N.Y.), 9 12, 1152-9

Hess-Wilson, J. K., Webb, S. L., Daly, H. K., Leung, Y., Boldison, J., Comstock, C. E. S., Sartor, M. A., Ho, S., & Knudsen, K. E. 2007. Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status. Environmental Health Perspectives, 115 11, 1646-53

Syed, V., Mukherjee, K., Godoy-Tundidor, S., & Ho, S. 2007. Progesterone induces apoptosis in TRAIL-resistant ovarian cancer cells by circumventing c-FLIPL overexpression. Journal of Cellular Biochemistry, 102 2, 442-52

Tam, N. N. C., Leav, I., & Ho, S. 2007. Sex hormones induce direct epithelial and inflammation-mediated oxidative/nitrosative stress that favors prostatic carcinogenesis in the noble rat. The American Journal of Pathology, 171 4, 1334-41

Tang, W., & Ho, S. 2007. Epigenetic reprogramming and imprinting in origins of disease. Reviews in Endocrine & Metabolic Disorders, 8 2, 173-82

Zhang, X., Leung, Y., & Ho, S. 2007. AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells. Oncogene, 26 52, 7346-54

Ho, S., Leung, Y., & Chung, I. 2006. Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer. Annals of the New York Academy of Sciences, 1089 , 177-93

Ho, S., Tang, W., Belmonte de Frausto, J., & Prins, G. S. 2006. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Research, 66 11, 5624-32

Languino, L. R., & Ho, S. 2006. Androgen action series. Journal of Cellular Biochemistry, 99 2, 331-2

Leung, Y., Gao, Y., Lau, K., Zhang, X., & Ho, S. 2006. ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk. Neoplasia (New York, N.Y.), 8 4, 242-9

Leung, Y., Mak, P., Hassan, S., & Ho, S. 2006. Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling. Proceedings of the National Academy of Sciences of the United States of America, 103 35, 13162-7

Mak, P., Leung, Y., Tang, W., Harwood, C., & Ho, S. 2006. Apigenin suppresses cancer cell growth through ERbeta. Neoplasia (New York, N.Y.), 8 11, 896-904

Sun, C. Q., Arnold, R., Fernandez-Golarz, C., Parrish, A. B., Almekinder, T., He, J., Ho, S., Svoboda, P., Pohl, J., Marshall, F. F., & Petros, J. A. 2006. Human beta-defensin-1, a potential chromosome 8p tumor suppressor: control of transcription and induction of apoptosis in renal cell carcinoma. Cancer Research, 66 17, 8542-9

Tam, N. N. C., Nyska, A., Maronpot, R. R., Kissling, G., Lomnitski, L., Suttie, A., Bakshi, S., Bergman, M., Grossman, S., & Ho, S. 2006. Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants. The Prostate, 66 1, 57-69

Kim, J., Sun, P., Lam, Y., Troncoso, P., Sabichi, A. L., Babaian, R. J., Pisters, L. L., Pettaway, C. A., Wood, C. G., Lippman, S. M., McDonnell, T. J., Lieberman, R., Logothetis, C., & Ho, S. 2005. Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology, 14 7, 1697-702

Lam, Y. W., Mobley, J. A., Evans, J. E., Carmody, J. F., & Ho, S. 2005. Mass profiling-directed isolation and identification of a stage-specific serologic protein biomarker of advanced prostate cancer. Proteomics, 5 11, 2927-38

Leung, Y., Lau, K., Mobley, J., Jiang, Z., & Ho, S. 2005. Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis. Cancer Research, 65 9, 3726-34

Mukherjee, K., Syed, V., & Ho, S. 2005. Estrogen-induced loss of progesterone receptor expression in normal and malignant ovarian surface epithelial cells. Oncogene, 24 27, 4388-400

Syed, V., Mukherjee, K., Lyons-Weiler, J., Lau, K., Mashima, T., Tsuruo, T., & Ho, S. 2005. Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling. Oncogene, 24 10, 1774-87

Syed, V., Zhang, X., Lau, K., Cheng, R., Mukherjee, K., & Ho, S. 2005. Profiling estrogen-regulated gene expression changes in normal and malignant human ovarian surface epithelial cells. Oncogene, 24 55, 8128-43

Bostwick, D. G., Burke, H. B., Djakiew, D., Euling, S., Ho, S., Landolph, J., Morrison, H., Sonawane, B., Shifflett, T., Waters, D. J., & Timms, B. 2004. Human prostate cancer risk factors. Cancer, 101 10 Suppl, 2371-490

Ho, S., & Cheng, R. Y. S. 2004. A promising bladder cancer detection assay: the HA-HAase test. The Journal of Urology, 172 3, 824-5

Ho, Shuk-Mei 2004. Estrogens and anti-estrogens: key mediators of prostate carcinogenesis and new therapeutic candidates. Journal of Cellular Biochemistry, 91 3, 491-503

Lai, J. S., Brown, L. G., True, L. D., Hawley, S. J., Etzioni, R. B., Higano, C. S., Ho, S., Vessella, R. L., & Corey, E. 2004. Metastases of prostate cancer express estrogen receptor-beta. Urology, 64 4, 814-20

Mobley, J. A., Lam, Y. W., Lau, K. M., Pais, V. M., L'Esperance, J. O., Steadman, B., Fuster, L. M. B., Blute, R. D., Taplin, M. E., & Ho, S. M. 2004. Monitoring the serological proteome: the latest modality in prostate cancer detection. The Journal of Urology, 172 1, 331-7

Mobley, J. A., L'Esperance, J. O., Wu, M., Friel, C. J., Hanson, R. H., & Ho, S. 2004. The novel estrogen 17alpha-20Z-21-[(4-amino)phenyl]-19-norpregna-1,3,5(10),20-tetraene-3,17beta-diol induces apoptosis in prostate cancer cell lines at nanomolar concentrations in vitro. Molecular Cancer Therapeutics, 3 5, 587-95

Wu, M., & Ho, S. 2004. PMP24, a gene identified by MSRF, undergoes DNA hypermethylation-associated gene silencing during cancer progression in an LNCaP model. Oncogene, 23 1, 250-9

Zhu, X., Leav, I., Leung, Y., Wu, M., Liu, Q., Gao, Y., McNeal, J. E., & Ho, S. 2004. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. The American Journal of Pathology, 164 6, 2003-12

Zielie, P. J., Mobley, J. A., Ebb, R. G., Jiang, Z., Blute, R. D., & Ho, S. M. 2004. A novel diagnostic test for prostate cancer emerges from the determination of alpha-methylacyl-coenzyme a racemase in prostatic secretions. The Journal of Urology, 172 3, 1130-3

Ho, S., Lau, K., Mok, S. C., & Syed, V. 2003. Profiling follicle stimulating hormone-induced gene expression changes in normal and malignant human ovarian surface epithelial cells. Oncogene, 22 27, 4243-56

Ho, Shuk-Mei 2003. Estrogen, progesterone and epithelial ovarian cancer. Reproductive Biology and Endocrinology : RB & E, 1 , 73

Kwong, J., Lui, K., Chan, P. S. F., Ho, S., Wong, Y. C., Xuan, J. W., & Chan, F. L. 2003. Expression study of three secretory proteins (prostatic secretory protein of 94 amino acids, probasin, and seminal vesicle secretion II) in dysplastic and neoplastic rat prostates. The Prostate, 56 2, 81-97

Lau, K., Tam, N. N. C., Thompson, C., Cheng, R. Y. S., Leung, Y., & Ho, S. 2003. Age-associated changes in histology and gene-expression profile in the rat ventral prostate. Laboratory Investigation; A Journal of Technical Methods and Pathology, 83 5, 743-57

Leav, I., McNeal, J. E., Ho, S., & Jiang, Z. 2003. Alpha-methylacyl-CoA racemase (P504S) expression in evolving carcinomas within benign prostatic hyperplasia and in cancers of the transition zone. Human Pathology, 34 3, 228-33

Mobley, J. A., Leav, I., Zielie, P., Wotkowitz, C., Evans, J., Lam, Y., L'Esperance, B. S., Jiang, Z., & Ho, S. 2003. Branched fatty acids in dairy and beef products markedly enhance alpha-methylacyl-CoA racemase expression in prostate cancer cells in vitro. Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology, 12 8, 775-83

Pais, V., Leav, I., Lau, K., Jiang, Z., & Ho, S. 2003. Estrogen receptor-beta expression in human testicular germ cell tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research, 9 12, 4475-82

Syed, V., & Ho, S. 2003. Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL. Oncogene, 22 44, 6883-90

Tam, N. N. C., Gao, Y., Leung, Y., & Ho, S. 2003. Androgenic regulation of oxidative stress in the rat prostate: involvement of NAD(P)H oxidases and antioxidant defense machinery during prostatic involution and regrowth. The American Journal of Pathology, 163 6, 2513-22

Tam, N. N. C., Ghatak, S., & Ho, S. 2003. Sex hormone-induced alterations in the activities of antioxidant enzymes and lipid peroxidation status in the prostate of Noble rats. The Prostate, 55 1, 1-8

Adams, J. Y., Leav, I., Lau, K., Ho, S., & Pflueger, S. M. V. 2002. Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate. The Prostate, 52 1, 69-81

Ho, S., & Lau, K. 2002. DNA microarrays in prostate cancer. Current Urology Reports, 3 1, 53-60

Melnick, R., Lucier, G., Wolfe, M., Hall, R., Stancel, G., Prins, G., Gallo, M., Reuhl, K., Ho, S., Brown, T., Moore, J., Leakey, J., Haseman, J., & Kohn, M. 2002. Summary of the National Toxicology Program's report of the endocrine disruptors low-dose peer review. Environmental Health Perspectives, 110 4, 427-31

Syed, V., Ulinski, G., Mok, S. C., & Ho, S. 2002. Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells. Journal of the National Cancer Institute, 94 8, 617-29

Tekur, S., & Ho, S. 2002. Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines. Molecular Carcinogenesis, 33 1, 44-55

Thompson, C. J., Tam, N. N. C., Joyce, J. M., Leav, I., & Ho, S. 2002. Gene expression profiling of testosterone and estradiol-17 beta-induced prostatic dysplasia in Noble rats and response to the antiestrogen ICI 182,780. Endocrinology, 143 6, 2093-105

Chan, F. L., Choi, H. L., & Ho, S. M. 2001. Analysis of glycoconjugate patterns of normal and hormone-induced dysplastic Noble rat prostates, and an androgen-independent Noble rat prostate tumor, by lectin histochemistry and protein blotting. The Prostate, 46 1, 21-32

Leav, I., Lau, K. M., Adams, J. Y., McNeal, J. E., Taplin, M. E., Wang, J., Singh, H., & Ho, S. M. 2001. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. The American Journal of Pathology, 159 1, 79-92

Lee, T. M., Ho, S. M., Tsang, L. Y., Yang, S. H., Li, L. S., Chan, C. C., & Yang, S. Y. 2001. Effect on human attention of exposure to the electromagnetic field emitted by mobile phones. Neuroreport, 12 4, 729-31

Li, S. C., Chen, G. F., Chan, P. S., Choi, H. L., Ho, S. M., & Chan, F. L. 2001. Altered expression of extracellular matrix and proteinases in Noble rat prostate gland after long-term treatment with sex steroids. The Prostate, 49 1, 58-71

Syed, V., Ulinski, G., Mok, S. C., Yiu, G. K., & Ho, S. M. 2001. Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelial cells. Cancer Research, 61 18, 6768-76

Taplin, M. E., & Ho, S. M. 2001. Clinical review 134: The endocrinology of prostate cancer. The Journal of Clinical Endocrinology and Metabolism, 86 8, 3467-77

Tekur, S., Lau, K. M., Long, J., Burnstein, K., & Ho, S. M. 2001. Expression of RFG/ELE1alpha/ARA70 in normal and malignant prostatic epithelial cell cultures and lines: regulation by methylation and sex steroids. Molecular Carcinogenesis, 30 1, 1-13

Kwong, J., Xuan, J. W., Chan, P. S., Ho, S. M., & Chan, F. L. 2000. A comparative study of hormonal regulation of three secretory proteins (prostatic secretory protein-PSP94, probasin, and seminal vesicle secretion II) in rat lateral prostate. Endocrinology, 141 12, 4543-51

Lau, K. M., LaSpina, M., Long, J., & Ho, S. M. 2000. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Research, 60 12, 3175-82

Rauh-Adelmann, C., Lau, K. M., Sabeti, N., Long, J. P., Mok, S. C., & Ho, S. M. 2000. Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines. Molecular Carcinogenesis, 28 4, 236-46

Chan, F. L., & Ho, S. M. 1999. Comparative study of glycoconjugates of the rat prostatic lobes by lectin histochemistry. The Prostate, 38 1, 1-16

Lau, K. M., Mok, S. C., & Ho, S. M. 1999. Expression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells. Proceedings of the National Academy of Sciences of the United States of America, 96 10, 5722-7

Leav, I., Merk, F. B., Lee, K. F., Loda, M., Mandoki, M., McNeal, J. E., & Ho, S. M. 1999. Prolactin receptor expression in the developing human prostate and in hyperplastic, dysplastic, and neoplastic lesions. The American Journal of Pathology, 154 3, 863-70

Lee, K. F., Lau, K. M., & Ho, S. M. 1999. Effects of cadmium on metallothionein-I and metallothionein-II mRNA expression in rat ventral, lateral, and dorsal prostatic lobes: quantification by competitive RT-PCR. Toxicology and Applied Pharmacology, 154 1, 20-7

Lee, K. F., Lau, K. M., & Ho, S. M. 1999. Generation and characterization of hammerhead ribozymes targeting rodent metallothionein-I and -II ribonucleic acid. Toxicology and Applied Pharmacology, 161 3, 294-301

Walker, C., Ahmed, S. A., Brown, T., Ho, S. M., Hodges, L., Lucier, G., Russo, J., Weigel, N., Weise, T., & Vandenbergh, J. 1999. Species, interindividual, and tissue specificity in endocrine signaling. Environmental Health Perspectives, 107 Suppl 4 , 619-24

Ho, S. M., Leav, I., Ghatak, S., Merk, F., Jagannathan, V. S., & Mallery, K. 1998. Lack of association between enhanced TRPM-2/clusterin expression and increased apoptotic activity in sex-hormone-induced prostatic dysplasia of the Noble rat. The American Journal of Pathology, 153 1, 131-9

Hu, Y. F., Lau, K. M., Ho, S. M., & Russo, J. 1998. Increased expression of estrogen receptor beta in chemically transformed human breast epithelial cells. International Journal of Oncology, 12 6, 1225-8

Lau, K. M., Leav, I., & Ho, S. M. 1998. Rat estrogen receptor-alpha and -beta, and progesterone receptor mRNA expression in various prostatic lobes and microdissected normal and dysplastic epithelial tissues of the Noble rats. Endocrinology, 139 1, 424-7

Lane, K. E., Leav, I., Ziar, J., Bridges, R. S., Rand, W. M., & Ho, S. M. 1997. Suppression of testosterone and estradiol-17beta-induced dysplasia in the dorsolateral prostate of Noble rats by bromocriptine. Carcinogenesis, 18 8, 1505-10

Lane, K. E., Ricci, M. J., & Ho, S. M. 1997. Effect of combined testosterone and estradiol-17 beta treatment on the metabolism of E2 in the prostate and liver of noble rats. The Prostate, 30 4, 256-62

Ghatak, S., Oliveria, P., Kaplan, P., & Ho, S. M. 1996. Expression and regulation of metallothionein mRNA levels in the prostates of noble rats: lack of expression in the ventral prostate and regulation by sex hormones in the dorsolateral prostate. The Prostate, 29 2, 91-100

Ghatak, S., & Ho, S. M. 1996. Age-related changes in the activities of antioxidant enzymes and lipid peroxidation status in ventral and dorsolateral prostate lobes of noble rats. Biochemical and Biophysical Research Communications, 222 2, 362-7

Kaplan, P. J., Leav, I., Greenwood, J., Kwan, P. W., & Ho, S. M. 1996. Involvement of transforming growth factor alpha (TGFalpha) and epidermal growth factor receptor (EGFR) in sex hormone-induced prostatic dysplasia and the growth of an androgen-independent transplantable carcinoma of the prostate. Carcinogenesis, 17 12, 2571-9

Leav, I., Galluzzi, C. M., Ziar, J., Stork, P. J., Ho, S. M., & Loda, M. 1996. Mitogen-activated protein kinase and mitogen-activated kinase phosphatase-1 expression in the Noble rat model of sex hormone-induced prostatic dysplasia and carcinoma. Laboratory Investigation; A Journal of Technical Methods and Pathology, 75 3, 361-70

Ho, S. M., Leav, I., Merk, F. B., Yu, M., Kwan, P. W., & Ziar, J. 1995. Induction of atypical hyperplasia, apoptosis, and type II estrogen-binding sites in the ventral prostates of Noble rats treated with testosterone and pharmacologic doses of estradiol-17 beta. Laboratory Investigation; A Journal of Technical Methods and Pathology, 73 3, 356-65

Ho, S. M., & Yu, M. 1995. Hormonal regulation of nuclear type II estrogen binding sites in the dorsolateral prostate of noble rats. The Journal of Steroid Biochemistry and Molecular Biology, 52 3, 233-8

Ho, S. M., & Roy, D. 1994. Sex hormone-induced nuclear DNA damage and lipid peroxidation in the dorsolateral prostates of Noble rats. Cancer Letters, 84 2, 155-62

Ho, S. M., & Yu, M. 1993. Selective increase in type II estrogen-binding sites in the dysplastic dorsolateral prostates of noble rats. Cancer Research, 53 3, 528-32

Yu, M., Leav, B. A., Leav, I., Merk, F. B., Wolfe, H. J., & Ho, S. M. 1993. Early alterations in ras protooncogene mRNA expression in testosterone and estradiol-17 beta induced prostatic dysplasia of noble rats. Laboratory Investigation; A Journal of Technical Methods and Pathology, 68 1, 33-44

Leav, I., Kwan, P. W., Merk, F. B., Chang, C., & Ho, S. M. 1992. Immunohistochemical and in situ hybridization studies of androgen receptor expression in a transplantable androgen-independent prostatic carcinoma line (AIT) of Noble rats. Laboratory Investigation; A Journal of Technical Methods and Pathology, 67 6, 788-95

Ho, S M 1991. Prostatic androgen receptor and plasma testosterone levels in streptozotocin-induced diabetic rats. The Journal of Steroid Biochemistry and Molecular Biology, 38 1, 67-72

Ho, S. M., Press, D., & Yu, M. S. 1989. Effects of hypophysectomy and ovariectomy on hepatic estrogen receptor content in the turtle, Chrysemys picta. General and Comparative Endocrinology, 75 3, 466-71

Leav, I., Merk, F. B., Kwan, P. W., & Ho, S. M. 1989. Androgen-supported estrogen-enhanced epithelial proliferation in the prostates of intact Noble rats. The Prostate, 15 1, 23-40

Yu, M. S., & Ho, S. M. 1989. Seasonal variation in hepatic binding of estrogen in the turtle, Chrysemys picta. General and Comparative Endocrinology, 75 3, 472-80

Yu, M. S., & Ho, S. M. 1989. Nuclear acceptor sites for estrogen-receptor complexes in the liver of the turtle, Chrysemys picta. I. Sexual differences, species specificity and hormonal dependency. Molecular and Cellular Endocrinology, 61 1, 37-48

Yu, M., Cates, J., Leav, I., & Ho, S. M. 1989. Heterogeneity of [3H]estradiol binding sites in the rat prostate: properties and distribution of type I and type II sites. Journal of Steroid Biochemistry, 33 3, 449-57

Ho, S. M., Fehrer, S., Yu, M., Liang, L. C., & Press, D. 1988. High-affinity binding of [3H]estradiol-17 beta by an estrogen receptor in the liver of the turtle. General and Comparative Endocrinology, 70 3, 382-94

Ho, S. M., Leav, I., Damassa, D., Kwan, P. W., Merk, F. B., & Seto, H. S. 1988. Testosterone-mediated increase in 5 alpha-dihydrotestosterone content, nuclear androgen receptor levels, and cell division in an androgen-independent prostate carcinoma of Noble rats. Cancer Research, 48 3, 609-14

Leav, I., Ho, S. M., Ofner, P., Merk, F. B., Kwan, P. W., & Damassa, D. 1988. Biochemical alterations in sex hormone-induced hyperplasia and dysplasia of the dorsolateral prostates of Noble rats. Journal of the National Cancer Institute, 80 13, 1045-53

Ho, S. M., Lance, V., & Megaloudis, M. 1987. Plasma sex-steroid binding protein in a seasonally breeding reptile, Alligator mississippiensis. General and Comparative Endocrinology, 65 1, 121-32

Ho, S. M., Press, D., Liang, L. C., & Sower, S. 1987. Identification of an estrogen receptor in the testis of the sea lamprey, Petromyzon marinus. General and Comparative Endocrinology, 67 1, 119-25

Ho, S. M., & Levin, V. 1986. Induction of progesterone receptor by androgens in the mouse uterus. Molecular and Cellular Endocrinology, 46 2, 103-8

Ho, S. M., & Ofner, P. 1986. Prostatic cytosol binding of 5 alpha-androstane-3 beta, 17 beta-diol and estradiol-17 beta. Steroids, 47 1, 21-34

Hecht, N. B., Liem, H., Kleene, K. C., Distel, R. J., & Ho, S. M. 1984. Maternal inheritance of the mouse mitochondrial genome is not mediated by a loss or gross alteration of the paternal mitochondrial DNA or by methylation of the oocyte mitochondrial DNA. Developmental Biology, 102 2, 452-61

Ho, S. M., & Callard, I. P. 1984. High affinity binding of [3H]R5020 and [3H]progesterone by putative progesterone receptors in cytosol and nuclear extract of turtle oviduct. Endocrinology, 114 1, 70-9

Mak, P., Ho, S. M., & Callard, I. P. 1983. Characterization of an estrogen receptor in the turtle testis. General and Comparative Endocrinology, 52 2, 182-9

Ho, S. M., Taylor, S., & Callard, I. P. 1982. Effect of hypophysectomy and growth hormone on estrogen-induced vitellogenesis in the freshwater turtle, Chrysemys picta. General and Comparative Endocrinology, 48 2, 254-60

Mak, P., Ho, S. M., & Callard, I. P. 1982. Estrogen receptors in the turtle brain. Brain Research, 231 1, 63-74

Ho, S. M., Danko, D., & Callard, I. P. 1981. Effect of exogenous estradiol-17beta on plasma vitellogenin levels in male and female Chrysemys and its modulation by testosterone and progesterone. General and Comparative Endocrinology, 43 4, 413-21

Ho, S. M., Tsang, P., & Callard, I. P. 1980. Some properties of a steroid-binding protein in the plasma of an ovoviviparous dogfish, Squalus acanthias, at different stages of the life cycle. Biology of Reproduction, 23 2, 281-9

Gapp, D. A., Ho, S. M., & Callard, I. P. 1979. Plasma levels of vitellogenin in Chrysemys picta during the annual gonadal cycle: measurement by specific radioimmunoassay. Endocrinology, 104 3, 784-90

Bosland, M. C., Chung, L. W., Greenberg, N. M., Ho, S. M., Isaacs, J. T., Lane, K., Peehl, D. M., Thompson, T. C., van Steenbrugge, G. J., & van Weerden, W. M. . Recent advances in the development of animal and cell culture models for prostate cancer research A minireview. Urologic Oncology, 2 4, 99

Ho, S. M., Damassa, D., Kwan, P. W., Seto, H. S., & Leav, I. . Androgen receptor levels and androgen contents in the prostate lobes of intact and testosterone-treated Noble rats. Journal of Andrology, 6 5, 279-90

Ho, S., & Tang, W. . Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: an emphasis on fetal-based adult diseases. Reproductive Toxicology (Elmsford, N.Y.), 23 3, 267-82

Keri, R. A., Ho, S., Hunt, P. A., Knudsen, K. E., Soto, A. M., & Prins, G. S. . An evaluation of evidence for the carcinogenic activity of bisphenol A. Reproductive Toxicology (Elmsford, N.Y.), 24 2, 240-52

Prins, G. S., Birch, L., Tang, W., & Ho, S. . Developmental estrogen exposures predispose to prostate carcinogenesis with aging. Reproductive Toxicology (Elmsford, N.Y.), 23 3, 374-82

vom Saal, F. S., Akingbemi, B. T., Belcher, S. M., Birnbaum, L. S., Crain, D. A., Eriksen, M., Farabollini, F., Guillette, L. J., Hauser, R., Heindel, J. J., Ho, S., Hunt, P. A., Iguchi, T., Jobling, S., Kanno, J., Keri, R. A., Knudsen, K. E., Laufer, H., LeBlanc, G. A., Marcus, M., McLachlan, J. A., Myers, J. P., Nadal, A., Newbold, R. R., Olea, N., Prins, G. S., Richter, C. A., Rubin, B. S., Sonnenschein, C., Soto, A. M., Talsness, C. E., Vandenbergh, J. G., Vandenberg, L. N., Walser-Kuntz, D. R., Watson, C. S., Welshons, W. V., Wetherill, Y., & Zoeller, R. T. . Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reproductive Toxicology (Elmsford, N.Y.), 24 2, 131-8