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Department of

Environmental Health

Aimin Chen, MD, PhD

Education/Credentials
  • MD: Nanjing Medical University
  • MS: Nanjing Medical University
  • PhD: Fudan University

Contact Information
  • 160 Panzeca Way
  • Kettering Lab Complex, Room 141
  • Cincinnati, Ohio 45267
  • Office 513-558-2129
  • Fax 513-558-4397
  • Email aimin.chen@uc.edu

Peer Reviewed Publications

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Braun, J. M.; Chen, A.; Romano, M. E.; Calafat, A. M.; Webster, G. M.; Yolton, K.; Lanphear, B. P.; 2016. Prenatal perfluoroalkyl substance exposure and child adiposity at 8 years of age: The HOME study. Obesity (Silver Spring, Md.), 24 1, 231-7

Braun, J. M.; Kalloo, G.; Chen, A.; Dietrich, K. N.; Liddy-Hicks, S.; Morgan, S.; Xu, Y.; Yolton, K.; Lanphear, B. P.; 2016. Cohort Profile: The Health Outcomes and Measures of the Environment (HOME) study. International journal of epidemiology, ,

DeFranco, E.; Moravec, W.; Xu, F.; Hall, E.; Hossain, M.; Haynes, E. N.; Muglia, L.; Chen, A.; 2016. Exposure to airborne particulate matter during pregnancy is associated with preterm birth: a population-based cohort study. Environmental health : a global access science source, 15 1, 6

Khalil, N.; Chen, A.; Lee, M.; Czerwinski, S. A.; Ebert, J. R.; DeWitt, J. C.; Kannan, K.; 2016. Association of Perfluoroalkyl Substances, Bone Mineral Density, and Osteoporosis in the U.S. Population in NHANES 2009-2010. Environmental health perspectives, 124 1, 81-7

Liu, R.; Xu, X.; Zhang, Y.; Zheng, X.; Kim, S. S.; Dietrich, K. N.; Ho, S.; Reponen, T.; Chen, A.; Huo, X.; 2016. Thyroid Hormone Status in Umbilical Cord Serum is Positively Associated with Male Anogenital Distance. The Journal of clinical endocrinology and metabolism, , jc20153872

Moore, E.; Blatt, K.; Chen, A.; Van H. J.; Defranco, E. A.; 2016. Relationship of trimester specific smoking patterns and risk of preterm birth. American journal of obstetrics and gynecology, ,

Romano, M. E.; Xu, Y.; Calafat, A. M.; Yolton, K.; Chen, A.; Webster, G. M.; Eliot, M. N.; Howard, C. R.; Lanphear, B. P.; Braun, J. M.; 2016. Maternal serum perfluoroalkyl substances during pregnancy and duration of breastfeeding. Environmental research, ,

Stacy, S. L.; Eliot, M.; Calafat, A. M.; Chen, A.; Lanphear, B.; Hauser, R.; Pap; onatos, G. D.; Sathyanarayana, S.; Ye, X.; Yolton, K.; Braun, J.; 2016. Patterns, Variability, and Predictors of Urinary Bisphenol A Concentrations during Childhood. Environmental science & technology, ,

Vuong, A. M.; Braun, J. M.; Sjödin,; reas; Webster, G. M.; Yolton, K.; Lanphear, B. P.; Chen, A.; 2016. Prenatal Polybrominated Diphenyl Ether Exposure and Body Mass Index in Children Up To 8 Years of Age. Environmental health perspectives, ,

Vuong, A. M.; Yolton, K.; Webster, G. M.; Sjödin,; reas; Calafat, A. M.; Braun, J. M.; Dietrich, K. N.; Lanphear, B. P.; Chen, A.; 2016. Prenatal polybrominated diphenyl ether and perfluoroalkyl substance exposures and executive function in school-age children. Environmental research, ,

Yekeen, T. A.; Xu, X.; Zhang, Y.; Wu, Y.; Kim, S.; Reponen, T.; Dietrich, K. N.; Ho, S.; Chen, A.; Huo, X.; 2016. Assessment of health risk of trace metal pollution in surface soil and road dust from e-waste recycling area in China. Environmental science and pollution research international, ,

Zeng, X.; Xu, X.; Zheng, X.; Reponen, T.; Chen, A.; Huo, X.; 2016. Heavy metals in PM2.5 and in blood, and children's respiratory symptoms and asthma from an e-waste recycling area. Environmental pollution (Barking, Essex : 1987), 210 , 346-353

Zhang, H.; Yolton, K.; Webster, G. M.; Sjödin,; reas; Calafat, A. M.; Dietrich, K. N.; Xu, Y.; Xie, C.; Braun, J. M.; Lanphear, B. P.; Chen, A.; 2016. Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children. Environmental health perspectives, ,

Blatt, K.; Moore, E.; Chen, A.; Van H. J.; DeFranco, E. A.; 2015. Association of reported trimester-specific smoking cessation with fetal growth restriction. Obstetrics and gynecology, 125 6, 1452-9

Chen, A.; Xu, F.; Xie, C.; Wu, T.; Vuong, A. M.; Miao, M.; Yuan, W.; DeFranco, E. A.; 2015. Gestational Weight Gain Trend and Population Attributable Risks of Adverse Fetal Growth Outcomes in Ohio. Paediatric and perinatal epidemiology, 29 4, 346-50

Chen, J.; Zhong, C.; Liang, H.; Yang, Y.; Zhang, O.; Gao, E.; Chen, A.; Yuan, W.; Wang, J.; Sun, F.; Miao, M.; 2015. The relationship between age at menarche and infertility among Chinese rural women. European journal of obstetrics, gynecology, and reproductive biology, 194 , 68-72

DeFranco, E.; Hall, E.; Hossain, M.; Chen, A.; Haynes, E. N.; Jones, D.; Ren, S.; Lu, L.; Muglia, L.; 2015. Air pollution and stillbirth risk: exposure to airborne particulate matter during pregnancy is associated with fetal death. PloS one, 10 3, e0120594

Donauer, S.; Chen, A.; Xu, Y.; Calafat, A. M.; Sjodin,; reas; Yolton, K.; 2015. Prenatal exposure to polybrominated diphenyl ethers and polyfluoroalkyl chemicals and infant neurobehavior. The Journal of pediatrics, 166 3, 736-42

Heacock, M.; Kelly, C. B.; Asante, K. A.; Birnbaum, L. S.; Bergman, A. L.; Bruné, M.; Buka, I.; Carpenter, D. O.; Chen, A.; Huo, X.; Kamel, M.; L; rigan, P. J.; Magalini, F.; Diaz-Barriga, F.; o; Neira, M.; Omar, M.; Pascale, A.; Ruchirawat, M.; Sly, L.; Sly, P. D.; Van d. B. M.; Suk, W. A.; 2015. E-Waste and Harm to Vulnerable Populations: A Growing Global Problem. Environmental health perspectives, ,

Moore, E.; Blatt, K.; Chen, A.; Van H. J.; DeFranco, E. A.; 2015. Factors Associated with Smoking Cessation in Pregnancy. American journal of perinatology, ,

Romano, M. E.; Webster, G. M.; Vuong, A. M.; Thomas Z. R.; Chen, A.; Hoofnagle,; rew N.; Calafat, A. M.; Karagas, M. R.; Yolton, K.; Lanphear, B. P.; Braun, J. M.; 2015. Gestational urinary bisphenol A and maternal and newborn thyroid hormone concentrations: the HOME Study. Environmental research, 138 , 453-60

Shen, Y.; Zheng, Y.; Jiang, J.; Liu, Y.; Luo, X.; Shen, Z.; Chen, X.; Wang, Y.; Dai, Y.; Zhao, J.; Liang, H.; Chen, A.; Yuan, W.; 2015. Higher urinary bisphenol A concentration is associated with unexplained recurrent miscarriage risk: evidence from a case-control study in eastern China. PloS one, 10 5, e0127886

Valent, A. M.; Newman, T.; Chen, A.; Thompson, A.; DeFranco, E.; 2015. Gestational age-specific neonatal morbidity among pregnancies complicated by advanced maternal age: a population-based retrospective cohort study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , 1-6

Vuong, A. M.; Webster, G. M.; Romano, M. E.; Braun, J. M.; Zoeller, R. T.; Hoofnagle,; rew N.; Sjödin,; reas; Yolton, K.; Lanphear, B. P.; Chen, A.; 2015. Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Thyroid Hormones in Maternal and Cord Sera: The HOME Study, Cincinnati, USA. Environmental health perspectives, 123 10, 1079-85

Yang, S.; Chen, A.; Wu, T.; 2015. Association of history of fracture with prehypertension and hypertension: a retrospective case-control study. BMC musculoskeletal disorders, 16 , 86

Braun, J. M.; Kalkbrenner, A. E.; Just, A. C.; Yolton, K.; Calafat, A. M.; Sjödin,; reas; Hauser, R.; Webster, G. M.; Chen, A.; Lanphear, B. P.; 2014. Gestational exposure to endocrine-disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4- and 5-year-old children: the HOME study. Environmental health perspectives, 122 5, 513-20

Chen, A.; Yolton, K.; Rauch, S. A.; Webster, G. M.; Hornung, R.; Sjödin,; reas; Dietrich, K. N.; Lanphear, B. P.; 2014. Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. children through 5 years of age: the HOME study. Environmental health perspectives, 122 8, 856-62

Kato, K.; Wong, L.; Chen, A.; Dunbar, C.; Webster, G. M.; Lanphear, B. P.; Calafat, A. M.; 2014. Changes in serum concentrations of maternal poly- and perfluoroalkyl substances over the course of pregnancy and predictors of exposure in a multiethnic cohort of Cincinnati, Ohio pregnant women during 2003-2006. Environmental science & technology, 48 16, 9600-8

Khalil, N.; Chen, A.; Lee, M.; 2014. Endocrine disruptive compounds and cardio-metabolic risk factors in children. Current opinion in pharmacology, 19C , 120-124

Wang, Y.; Chen, A.; Dietrich, K. N.; Radcliffe, J.; Caldwell, K. L.; Rogan, W. J.; 2014. Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old urban inner-city children exposed to lead in the United States. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 20 5, 527-38

Xu, X.; Liu, J.; Zeng, X.; Lu, F.; Chen, A.; Huo, X.; 2014. Elevated serum polybrominated diphenyl ethers and alteration of thyroid hormones in children from guiyu, china. PloS one, 9 11, e113699

Cao, Y.; Chen, A.; Bottai, M.; Caldwell, K. L.; Rogan, W. J.; 2013. The impact of succimer chelation on blood cadmium in children with background exposures: a randomized trial. The Journal of pediatrics, 163 2, 598-600

Chen, A.; Kim, S. S.; Chung, E.; Dietrich, K. N.; 2013. Thyroid hormones in relation to lead, mercury, and cadmium exposure in the National Health and Nutrition Examination Survey, 2007-2008. Environmental health perspectives, 121 2, 181-6

Chen, A.; Park, J.; Linderholm, L.; Rhee, A.; ra; Petreas, M.; DeFranco, E. A.; Dietrich, K. N.; Ho, S.; 2013. Hydroxylated polybrominated diphenyl ethers in paired maternal and cord sera. Environmental science & technology, 47 8, 3902-8

Kamath-Rayne, B. D.; DeFranco, E. A.; Chung, E.; Chen, A.; 2013. Subtypes of preterm birth and the risk of postneonatal death. The Journal of pediatrics, 162 1, 28-34.e2

Kim, S.; Arora, M.; Fern; ez, C.; L; ero, J.; Caruso, J.; Chen, A.; 2013. Lead, mercury, and cadmium exposure and attention deficit hyperactivity disorder in children. Environmental research, 126 , 105-10

Haynes, E. N.; Ryan, P.; Chen, A.; Brown, D.; Roda, S.; y; Kuhnell, P.; Wittberg, D.; Terrell, M.; Reponen, T.; 2012. Assessment of personal exposure to manganese in children living near a ferromanganese refinery. The Science of the total environment, 427-428 , 19-25

Loftin, R.; Chen, A.; Evans, A.; DeFranco, E.; 2012. Racial differences in gestational age-specific neonatal morbidity: further evidence for different gestational lengths. American journal of obstetrics and gynecology, 206 3, 259.e1-6

Xu, X.; Yang, H.; Chen, A.; Zhou, Y.; Wu, K.; Liu, J.; Zhang, Y.; Huo, X.; 2012. Birth outcomes related to informal e-waste recycling in Guiyu, China. Reproductive toxicology (Elmsford, N.Y.), 33 1, 94-8

Akhtar, J. I.; Irazuzta, J.; Chen, A.; 2011. Learner's evaluation in paediatric intensive care unit. Emergency medicine journal : EMJ, 28 9, 758-60

Cao, Y.; Chen, A.; Jones, R. L.; Radcliffe, J.; Dietrich, K. N.; Caldwell, K. L.; Peddada, S.; Rogan, W. J.; 2011. Efficacy of succimer chelation of mercury at background exposures in toddlers: a randomized trial. The Journal of pediatrics, 158 3, 480-485.e1

Chen, A.; Chung, E.; DeFranco, E. A.; Pinney, S. M.; Dietrich, K. N.; 2011. Serum PBDEs and age at menarche in adolescent girls: analysis of the National Health and Nutrition Examination Survey 2003-2004. Environmental research, 111 6, 831-7

Chen, A.; Dietrich, K. N.; Huo, X.; Ho, S.; 2011. Developmental neurotoxicants in e-waste: an emerging health concern. Environmental health perspectives, 119 4, 431-8

Haynes, E. N.; Chen, A.; Ryan, P.; Succop, P.; Wright, J.; Dietrich, K. N.; 2011. Exposure to airborne metals and particulate matter and risk for youth adjudicated for criminal activity. Environmental research, 111 8, 1243-8

Liang, H.; Gao, E.; Chen, A.; Luo, L.; Cheng, Y.; Yuan, W.; 2011. Mifepristone-induced abortion and vaginal bleeding in subsequent pregnancy. Contraception, 84 6, 609-14

Liu, J.; Xu, X.; Wu, K.; Piao, Z.; Huang, J.; Guo, Y.; Li, W.; Zhang, Y.; Chen, A.; Huo, X.; 2011. Association between lead exposure from electronic waste recycling and child temperament alterations. Neurotoxicology, 32 4, 458-64

Shen, X.; Nair, C.; ra K.; Aronow, W. S.; Holmberg, M. J.; Reddy, M.; An; , K.; Hee, T.; Chen, A.; Fang, X.; Maciejewski, S.; Esterbrooks, D. J.; 2011. A new baseline scoring system may help to predict response to cardiac resynchronization therapy. Archives of medical science : AMS, 7 4, 627-33

Alla, V. M.; An; , K.; Hundal, M.; eep; Chen, A.; Karnam, S.; Hee, T.; Hunter, C.; Mooss, A. N.; Esterbrooks, D.; Mohiuddin, S. M.; 2010. Impact of moderate to severe renal impairment on mortality and appropriate shocks in patients with implantable cardioverter defibrillators. Cardiology research and practice, 2010 , 150285

Cao, Y.; Chen, A.; Jones, R. L.; Radcliffe, J.; Caldwell, K. L.; Dietrich, K. N.; Rogan, W. J.; 2010. Does background postnatal methyl mercury exposure in toddlers affect cognition and behavior? Neurotoxicology, 31 1, 1-9

Guo, Y.; Huo, X.; Li, Y.; Wu, K.; Liu, J.; Huang, J.; Zheng, G.; Xiao, Q.; Yang, H.; Wang, Y.; Chen, A.; Xu, X.; 2010. Monitoring of lead, cadmium, chromium and nickel in placenta from an e-waste recycling town in China. The Science of the total environment, 408 16, 3113-7

Ma, J.; Lu, H.; Xia, Y.; Dong, H.; Gu, A.; Li, Z.; Li, Z.; Chen, A.; Wang, X.; Wang, S.; 2010. BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population. Biology of reproduction, 83 4, 656-62

Miao, M.; Gao, E.; Chen, A.; Luo, L.; Cheng, Y.; Yuan, W.; 2010. Mifepristone-induced abortion and duration of third stage labour in a subsequent pregnancy. Paediatric and perinatal epidemiology, 24 2, 125-30

Cao, Y.; Chen, A.; Radcliffe, J.; Dietrich, K. N.; Jones, R. L.; Caldwell, K.; Rogan, W. J.; 2009. Postnatal cadmium exposure, neurodevelopment, and blood pressure in children at 2, 5, and 7 years of age. Environmental health perspectives, 117 10, 1580-6

Chen, A.; Feresu, S. A.; Barsoom, M. J.; 2009. Heterogeneity of preterm birth subtypes in relation to neonatal death. Obstetrics and gynecology, 114 3, 516-22

Chen, A.; Feresu, S. A.; Fern; ez, C.; Rogan, W. J.; 2009. Maternal obesity and the risk of infant death in the United States. Epidemiology (Cambridge, Mass.), 20 1, 74-81

Chen, A.; Klebanoff, M. A.; Basso, O.; 2009. Pre-pregnancy body mass index change between pregnancies and preterm birth in the following pregnancy. Paediatric and perinatal epidemiology, 23 3, 207-15

Eskenazi, B.; Chevrier, J.; Rosas, L. G.; ; erson, H. A.; Bornman, M. S.; Bouwman, H.; Chen, A.; Cohn, B. A.; de J. C.; Henshel, D. S.; Leipzig, F.; Leipzig, J. S.; Lorenz, E. C.; Snedeker, S. M.; Stapleton, D.; 2009. The Pine River statement: human health consequences of DDT use. Environmental health perspectives, 117 9, 1359-67

Gonsalves, W. I.; Cornish, N.; Moore, M.; Chen, A.; Varman, M.; 2009. Effects of volume and site of blood draw on blood culture results. Journal of clinical microbiology, 47 11, 3482-5

Pomajzl, R. J.; Varman, M.; Holst, A.; Chen, A.; 2009. Hemolytic uremic syndrome (HUS)--incidence and etiologies at a regional Children's Hospital in 2001-2006. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 28 12, 1431-5

Zhu, Q.; Gao, E.; Chen, A.; Luo, L.; Cheng, Y.; Yuan, W.; 2009. Mifepristone-induced abortion and placental complications in subsequent pregnancy. Human reproduction (Oxford, England), 24 2, 315-9

Chen, A.; Basso, O.; 2007. Does low maternal blood pressure during pregnancy increase the risk of perinatal death? Epidemiology (Cambridge, Mass.), 18 5, 619-22

Chen, A.; Cai, B.; Dietrich, K. N.; Radcliffe, J.; Rogan, W. J.; 2007. Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ? Pediatrics, 119 3, e650-8

Chen, A.; Pennell, M. L.; Klebanoff, M. A.; Rogan, W. J.; Longnecker, M. P.; 2006. Maternal smoking during pregnancy in relation to child overweight: follow-up to age 8 years. International journal of epidemiology, 35 1, 121-30

Chen, A.; Rhoads, G. G.; Cai, B.; Salganik, M.; Rogan, W. J.; 2006. The effect of chelation on blood pressure in lead-exposed children: a randomized study. Environmental health perspectives, 114 4, 579-83

Chen, A.; Schwarz, D.; Radcliffe, J.; Rogan, W. J.; 2006. Maternal IQ, child IQ, behavior, and achievement in urban 5-7 year olds. Pediatric research, 59 3, 471-7

Chen, A.; Dietrich, K. N.; Ware, J. H.; Radcliffe, J.; Rogan, W. J.; 2005. IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environmental health perspectives, 113 5, 597-601

Chen, A.; Rogan, W. J.; 2005. Improving behavior of lead-exposed children: micronutrient supplementation, chelation, or prevention. The Journal of pediatrics, 147 5, 570-1

Chen, A.; Zhang, J.; Zhou, L.; Gao, E.; Chen, L.; Rogan, W. J.; Wolff, M. S.; 2005. DDT serum concentration and menstruation among young Chinese women. Environmental research, 99 3, 397-402

Rogan, W. J.; Chen, A.; 2005. Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT). Lancet, 366 9487, 763-73

Chen, A.; Rogan, W. J.; 2004. Breastfeeding and the risk of postneonatal death in the United States. Pediatrics, 113 5, e435-9

Chen, A.; Rogan, W. J.; 2004. Isoflavones in soy infant formula: a review of evidence for endocrine and other activity in infants. Annual review of nutrition, 24 , 33-54

Chen, A.; Yuan, W.; Meirik, O.; Wang, X.; Wu, S.; Zhou, L.; Luo, L.; Gao, E.; Cheng, Y.; 2004. Mifepristone-induced early abortion and outcome of subsequent wanted pregnancy. American journal of epidemiology, 160 2, 110-7

Chen, A.; Rogan, W. J.; 2003. Nonmalarial infant deaths and DDT use for malaria control. Emerging infectious diseases, 9 8, 960-4