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Department of

Environmental Health

Aimin Chen, MD, PhD

  • MD: Nanjing Medical University
  • MS: Nanjing Medical University
  • PhD: Fudan University

Contact Information
  • 160 Panzeca Way
  • Kettering Lab Complex, Room 141
  • Cincinnati, Ohio 45267
  • Office 513-558-2129
  • Fax 513-558-4397
  • Email

Peer Reviewed Publications

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Braun, J. M., Chen, A., Romano, M. E., Calafat, A. M., Webster, G. M., Yolton, K., & Lanphear, B. P. 2016. Prenatal perfluoroalkyl substance exposure and child adiposity at 8 years of age: The HOME study. Obesity (Silver Spring, Md.), 24 1, 231-7

DeFranco, E., Moravec, W., Xu, F., Hall, E., Hossain, M., Haynes, E. N., Muglia, L., & Chen, A. 2016. Exposure to airborne particulate matter during pregnancy is associated with preterm birth: a population-based cohort study. Environmental Health : A Global Access Science Source, 15 1, 6

Khalil, N., Chen, A., Lee, M., Czerwinski, S. A., Ebert, J. R., DeWitt, J. C., & Kannan, K. 2016. Association of Perfluoroalkyl Substances, Bone Mineral Density, and Osteoporosis in the U.S. Population in NHANES 2009-2010. Environmental Health Perspectives, 124 1, 81-7

Moore, E., Blatt, K., Chen, A., Van Hook, J., & Defranco, E. A. 2016. Relationship of trimester specific smoking patterns and risk of preterm birth. American Journal of Obstetrics and Gynecology, ,

Vuong, A. M., Yolton, K., Webster, G. M., Sjödin, A., Calafat, A. M., Braun, J. M., Dietrich, K. N., Lanphear, B. P., & Chen, A. 2016. Prenatal polybrominated diphenyl ether and perfluoroalkyl substance exposures and executive function in school-age children. Environmental Research, ,

Zeng, X., Xu, X., Zheng, X., Reponen, T., Chen, A., & Huo, X. 2016. Heavy metals in PM2.5 and in blood, and children's respiratory symptoms and asthma from an e-waste recycling area. Environmental Pollution (Barking, Essex : 1987), 210 , 346-353

Blatt, K., Moore, E., Chen, A., Van Hook, J., & DeFranco, E. A. 2015. Association of reported trimester-specific smoking cessation with fetal growth restriction. Obstetrics and Gynecology, 125 6, 1452-9

Chen, A., Xu, F., Xie, C., Wu, T., Vuong, A. M., Miao, M., Yuan, W., & DeFranco, E. A. 2015. Gestational Weight Gain Trend and Population Attributable Risks of Adverse Fetal Growth Outcomes in Ohio. Paediatric and Perinatal Epidemiology, 29 4, 346-50

Chen, J., Zhong, C., Liang, H., Yang, Y., Zhang, O., Gao, E., Chen, A., Yuan, W., Wang, J., Sun, F., & Miao, M. 2015. The relationship between age at menarche and infertility among Chinese rural women. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 194 , 68-72

DeFranco, E., Hall, E., Hossain, M., Chen, A., Haynes, E. N., Jones, D., Ren, S., Lu, L., & Muglia, L. 2015. Air pollution and stillbirth risk: exposure to airborne particulate matter during pregnancy is associated with fetal death. PloS One, 10 3, e0120594

Donauer, S., Chen, A., Xu, Y., Calafat, A. M., Sjodin, A., & Yolton, K. 2015. Prenatal exposure to polybrominated diphenyl ethers and polyfluoroalkyl chemicals and infant neurobehavior. The Journal of Pediatrics, 166 3, 736-42

Heacock, M., Kelly, C. B., Asante, K. A., Birnbaum, L. S., Bergman, A. L., Bruné, M., Buka, I., Carpenter, D. O., Chen, A., Huo, X., Kamel, M., Landrigan, P. J., Magalini, F., Diaz-Barriga, F., Neira, M., Omar, M., Pascale, A., Ruchirawat, M., Sly, L., Sly, P. D., Van den Berg, M., & Suk, W. A. 2015. E-Waste and Harm to Vulnerable Populations: A Growing Global Problem. Environmental Health Perspectives, ,

Moore, E., Blatt, K., Chen, A., Van Hook, J., & DeFranco, E. A. 2015. Factors Associated with Smoking Cessation in Pregnancy. American Journal of Perinatology, ,

Romano, M. E., Webster, G. M., Vuong, A. M., Thomas Zoeller, R., Chen, A., Hoofnagle, A. N., Calafat, A. M., Karagas, M. R., Yolton, K., Lanphear, B. P., & Braun, J. M. 2015. Gestational urinary bisphenol A and maternal and newborn thyroid hormone concentrations: the HOME Study. Environmental Research, 138 , 453-60

Shen, Y., Zheng, Y., Jiang, J., Liu, Y., Luo, X., Shen, Z., Chen, X., Wang, Y., Dai, Y., Zhao, J., Liang, H., Chen, A., & Yuan, W. 2015. Higher urinary bisphenol A concentration is associated with unexplained recurrent miscarriage risk: evidence from a case-control study in eastern China. PloS One, 10 5, e0127886

Valent, A. M., Newman, T., Chen, A., Thompson, A., & DeFranco, E. 2015. Gestational age-specific neonatal morbidity among pregnancies complicated by advanced maternal age: a population-based retrospective cohort study. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , 1-6

Vuong, A. M., Webster, G. M., Romano, M. E., Braun, J. M., Zoeller, R. T., Hoofnagle, A. N., Sjödin, A., Yolton, K., Lanphear, B. P., & Chen, A. 2015. Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Thyroid Hormones in Maternal and Cord Sera: The HOME Study, Cincinnati, USA. Environmental Health Perspectives, 123 10, 1079-85

Yang, S., Chen, A., & Wu, T. 2015. Association of history of fracture with prehypertension and hypertension: a retrospective case-control study. BMC Musculoskeletal Disorders, 16 , 86

Braun, J. M., Kalkbrenner, A. E., Just, A. C., Yolton, K., Calafat, A. M., Sjödin, A., Hauser, R., Webster, G. M., Chen, A., & Lanphear, B. P. 2014. Gestational exposure to endocrine-disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4- and 5-year-old children: the HOME study. Environmental Health Perspectives, 122 5, 513-20

Chen, A., Yolton, K., Rauch, S. A., Webster, G. M., Hornung, R., Sjödin, A., Dietrich, K. N., & Lanphear, B. P. 2014. Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. children through 5 years of age: the HOME study. Environmental Health Perspectives, 122 8, 856-62

Kato, K., Wong, L., Chen, A., Dunbar, C., Webster, G. M., Lanphear, B. P., & Calafat, A. M. 2014. Changes in serum concentrations of maternal poly- and perfluoroalkyl substances over the course of pregnancy and predictors of exposure in a multiethnic cohort of Cincinnati, Ohio pregnant women during 2003-2006. Environmental Science & Technology, 48 16, 9600-8

Khalil, N., Chen, A., & Lee, M. 2014. Endocrine disruptive compounds and cardio-metabolic risk factors in children. Current Opinion in Pharmacology, 19C , 120-124

Wang, Y., Chen, A., Dietrich, K. N., Radcliffe, J., Caldwell, K. L., & Rogan, W. J. 2014. Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old urban inner-city children exposed to lead in the United States. Child Neuropsychology : A Journal on Normal and Abnormal Development in Childhood and Adolescence, 20 5, 527-38

Xu, X., Liu, J., Zeng, X., Lu, F., Chen, A., & Huo, X. 2014. Elevated serum polybrominated diphenyl ethers and alteration of thyroid hormones in children from guiyu, china. PloS One, 9 11, e113699

Cao, Y., Chen, A., Bottai, M., Caldwell, K. L., & Rogan, W. J. 2013. The impact of succimer chelation on blood cadmium in children with background exposures: a randomized trial. The Journal of Pediatrics, 163 2, 598-600

Chen, A., Kim, S. S., Chung, E., & Dietrich, K. N. 2013. Thyroid hormones in relation to lead, mercury, and cadmium exposure in the National Health and Nutrition Examination Survey, 2007-2008. Environmental Health Perspectives, 121 2, 181-6

Chen, A., Park, J., Linderholm, L., Rhee, A., Petreas, M., DeFranco, E. A., Dietrich, K. N., & Ho, S. 2013. Hydroxylated polybrominated diphenyl ethers in paired maternal and cord sera. Environmental Science & Technology, 47 8, 3902-8

Kamath-Rayne, B. D., DeFranco, E. A., Chung, E., & Chen, A. 2013. Subtypes of preterm birth and the risk of postneonatal death. The Journal of Pediatrics, 162 1, 28-34.e2

Kim, S., Arora, M., Fernandez, C., Landero, J., Caruso, J., & Chen, A. 2013. Lead, mercury, and cadmium exposure and attention deficit hyperactivity disorder in children. Environmental Research, 126 , 105-10

Haynes, E. N., Ryan, P., Chen, A., Brown, D., Roda, S., Kuhnell, P., Wittberg, D., Terrell, M., & Reponen, T. 2012. Assessment of personal exposure to manganese in children living near a ferromanganese refinery. The Science of the Total Environment, 427-428 , 19-25

Loftin, R., Chen, A., Evans, A., & DeFranco, E. 2012. Racial differences in gestational age-specific neonatal morbidity: further evidence for different gestational lengths. American Journal of Obstetrics and Gynecology, 206 3, 259.e1-6

Xu, X., Yang, H., Chen, A., Zhou, Y., Wu, K., Liu, J., Zhang, Y., & Huo, X. 2012. Birth outcomes related to informal e-waste recycling in Guiyu, China. Reproductive Toxicology (Elmsford, N.Y.), 33 1, 94-8

Akhtar, J. I., Irazuzta, J., & Chen, A. 2011. Learner's evaluation in paediatric intensive care unit. Emergency Medicine Journal : EMJ, 28 9, 758-60

Cao, Y., Chen, A., Jones, R. L., Radcliffe, J., Dietrich, K. N., Caldwell, K. L., Peddada, S., & Rogan, W. J. 2011. Efficacy of succimer chelation of mercury at background exposures in toddlers: a randomized trial. The Journal of Pediatrics, 158 3, 480-485.e1

Chen, A., Chung, E., DeFranco, E. A., Pinney, S. M., & Dietrich, K. N. 2011. Serum PBDEs and age at menarche in adolescent girls: analysis of the National Health and Nutrition Examination Survey 2003-2004. Environmental Research, 111 6, 831-7

Chen, A., Dietrich, K. N., Huo, X., & Ho, S. 2011. Developmental neurotoxicants in e-waste: an emerging health concern. Environmental Health Perspectives, 119 4, 431-8

Haynes, E. N., Chen, A., Ryan, P., Succop, P., Wright, J., & Dietrich, K. N. 2011. Exposure to airborne metals and particulate matter and risk for youth adjudicated for criminal activity. Environmental Research, 111 8, 1243-8

Liang, H., Gao, E., Chen, A., Luo, L., Cheng, Y., & Yuan, W. 2011. Mifepristone-induced abortion and vaginal bleeding in subsequent pregnancy. Contraception, 84 6, 609-14

Liu, J., Xu, X., Wu, K., Piao, Z., Huang, J., Guo, Y., Li, W., Zhang, Y., Chen, A., & Huo, X. 2011. Association between lead exposure from electronic waste recycling and child temperament alterations. Neurotoxicology, 32 4, 458-64

Shen, X., Nair, C. K., Aronow, W. S., Holmberg, M. J., Reddy, M., Anand, K., Hee, T., Chen, A., Fang, X., Maciejewski, S., & Esterbrooks, D. J. 2011. A new baseline scoring system may help to predict response to cardiac resynchronization therapy. Archives of Medical Science : AMS, 7 4, 627-33

Alla, V. M., Anand, K., Hundal, M., Chen, A., Karnam, S., Hee, T., Hunter, C., Mooss, A. N., Esterbrooks, D., & Mohiuddin, S. M. 2010. Impact of moderate to severe renal impairment on mortality and appropriate shocks in patients with implantable cardioverter defibrillators. Cardiology Research and Practice, 2010 , 150285

Cao, Y., Chen, A., Jones, R. L., Radcliffe, J., Caldwell, K. L., Dietrich, K. N., & Rogan, W. J. 2010. Does background postnatal methyl mercury exposure in toddlers affect cognition and behavior? Neurotoxicology, 31 1, 1-9

Guo, Y., Huo, X., Li, Y., Wu, K., Liu, J., Huang, J., Zheng, G., Xiao, Q., Yang, H., Wang, Y., Chen, A., & Xu, X. 2010. Monitoring of lead, cadmium, chromium and nickel in placenta from an e-waste recycling town in China. The Science of the Total Environment, 408 16, 3113-7

Ma, J., Lu, H., Xia, Y., Dong, H., Gu, A., Li, Z., Li, Z., Chen, A., Wang, X., & Wang, S. 2010. BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population. Biology of Reproduction, 83 4, 656-62

Miao, M., Gao, E., Chen, A., Luo, L., Cheng, Y., & Yuan, W. 2010. Mifepristone-induced abortion and duration of third stage labour in a subsequent pregnancy. Paediatric and Perinatal Epidemiology, 24 2, 125-30

Cao, Y., Chen, A., Radcliffe, J., Dietrich, K. N., Jones, R. L., Caldwell, K., & Rogan, W. J. 2009. Postnatal cadmium exposure, neurodevelopment, and blood pressure in children at 2, 5, and 7 years of age. Environmental Health Perspectives, 117 10, 1580-6

Chen, A., Feresu, S. A., Fernandez, C., & Rogan, W. J. 2009. Maternal obesity and the risk of infant death in the United States. Epidemiology (Cambridge, Mass.), 20 1, 74-81

Chen, A., Feresu, S. A., & Barsoom, M. J. 2009. Heterogeneity of preterm birth subtypes in relation to neonatal death. Obstetrics and Gynecology, 114 3, 516-22

Chen, A., Klebanoff, M. A., & Basso, O. 2009. Pre-pregnancy body mass index change between pregnancies and preterm birth in the following pregnancy. Paediatric and Perinatal Epidemiology, 23 3, 207-15

Eskenazi, B., Chevrier, J., Rosas, L. G., Anderson, H. A., Bornman, M. S., Bouwman, H., Chen, A., Cohn, B. A., de Jager, C., Henshel, D. S., Leipzig, F., Leipzig, J. S., Lorenz, E. C., Snedeker, S. M., & Stapleton, D. 2009. The Pine River statement: human health consequences of DDT use. Environmental Health Perspectives, 117 9, 1359-67

Gonsalves, W. I., Cornish, N., Moore, M., Chen, A., & Varman, M. 2009. Effects of volume and site of blood draw on blood culture results. Journal of Clinical Microbiology, 47 11, 3482-5

Pomajzl, R. J., Varman, M., Holst, A., & Chen, A. 2009. Hemolytic uremic syndrome (HUS)--incidence and etiologies at a regional Children's Hospital in 2001-2006. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 28 12, 1431-5

Zhu, Q., Gao, E., Chen, A., Luo, L., Cheng, Y., & Yuan, W. 2009. Mifepristone-induced abortion and placental complications in subsequent pregnancy. Human Reproduction (Oxford, England), 24 2, 315-9

Chen, A., Cai, B., Dietrich, K. N., Radcliffe, J., & Rogan, W. J. 2007. Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ? Pediatrics, 119 3, e650-8

Chen, A., & Basso, O. 2007. Does low maternal blood pressure during pregnancy increase the risk of perinatal death? Epidemiology (Cambridge, Mass.), 18 5, 619-22

Chen, A., Pennell, M. L., Klebanoff, M. A., Rogan, W. J., & Longnecker, M. P. 2006. Maternal smoking during pregnancy in relation to child overweight: follow-up to age 8 years. International Journal of Epidemiology, 35 1, 121-30

Chen, A., Rhoads, G. G., Cai, B., Salganik, M., & Rogan, W. J. 2006. The effect of chelation on blood pressure in lead-exposed children: a randomized study. Environmental Health Perspectives, 114 4, 579-83

Chen, A., Schwarz, D., Radcliffe, J., & Rogan, W. J. 2006. Maternal IQ, child IQ, behavior, and achievement in urban 5-7 year olds. Pediatric Research, 59 3, 471-7

Chen, A., Dietrich, K. N., Ware, J. H., Radcliffe, J., & Rogan, W. J. 2005. IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environmental Health Perspectives, 113 5, 597-601

Chen, A., Zhang, J., Zhou, L., Gao, E., Chen, L., Rogan, W. J., & Wolff, M. S. 2005. DDT serum concentration and menstruation among young Chinese women. Environmental Research, 99 3, 397-402

Chen, A., & Rogan, W. J. 2005. Improving behavior of lead-exposed children: micronutrient supplementation, chelation, or prevention. The Journal of Pediatrics, 147 5, 570-1

Rogan, W. J., & Chen, A. 2005. Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT). Lancet, 366 9487, 763-73

Chen, A., Yuan, W., Meirik, O., Wang, X., Wu, S., Zhou, L., Luo, L., Gao, E., & Cheng, Y. 2004. Mifepristone-induced early abortion and outcome of subsequent wanted pregnancy. American Journal of Epidemiology, 160 2, 110-7

Chen, A., & Rogan, W. J. 2004. Breastfeeding and the risk of postneonatal death in the United States. Pediatrics, 113 5, e435-9

Chen, A., & Rogan, W. J. 2004. Isoflavones in soy infant formula: a review of evidence for endocrine and other activity in infants. Annual Review of Nutrition, 24 , 33-54

Chen, A., & Rogan, W. J. 2003. Nonmalarial infant deaths and DDT use for malaria control. Emerging Infectious Diseases, 9 8, 960-4