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Department of

Environmental Health

Photo of  C. Ralph Buncher, ScD, MS

C. Ralph Buncher, ScD, MS

Education/Credentials
  • BS: Massachusetts Institute of Technology
  • MS: Harvard University
  • Sc.D.: Harvard University

Contact Information

Peer Reviewed Publications

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Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph 2016. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. The New England journal of medicine, 374 2, 113-23

Jenkins, Todd M; Buncher, C Ralph; Akers, Rachel; Daniels, Stephen R; Lawson, M Louise; Khoury, Philip R; Wilson, Tawny P; Inge, Thomas H 2013. Validation of a weight history questionnaire to identify adolescent obesity. Obesity surgery, 23 9, 1404-12

Yap, Tracey L; Kennerly, Susan M; Simmons, Mark R; Buncher, Charles R; Miller, Elaine; Kim, Jay; Yap, Winston Y 2013. Multidimensional team-based intervention using musical cues to reduce odds of facility-acquired pressure ulcers in long-term care: a paired randomized intervention study. Journal of the American Geriatrics Society, 61 9, 1552-9

Shire, Norah J; Rao, Marepalli B; Succop, Paul; Buncher, C Ralph; Andersen, Janet A; Butt, Adeel A; Chung, Raymond T; Sherman, Kenneth E 2009. Improving noninvasive methods of assessing liver fibrosis in patients with hepatitis C virus/human immunodeficiency virus co-infection. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 7 4, 471-80, 480.e1-2

Anderson, Marshall W; Goodin, Colleen; Zhang, Yu; Kim, Sangmi; Estensen, Richard D; Wiedmann, Timothy S; Sekar, Padmini; Buncher, C Ralph; Khoury, Jane C; Garbow, Joel R; You, Ming; Tichelaar, Jay W 2008. Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice. Carcinogenesis, 29 8, 1594-600

Bedard, Angela C; Huether, Carl A; Shooner, Kerry; Buncher, C Ralph; Warren, Nancy Steinberg 2007. Career research interests and training of genetic counseling students. Journal of genetic counseling, 16 5, 645-53

Comstock, C E S; Revelo, M P; Buncher, C R; Knudsen, K E 2007. Impact of differential cyclin D1 expression and localisation in prostate cancer. British journal of cancer, 96 6, 970-9

Clark, Heather M; Gamm, Jennifer; Huether, Carl A; Buncher, C Ralph; Pfau, Ruthann I Blough; Warren, Nancy Steinberg 2006. Genetic counselors and research: current practices and future directions. American journal of medical genetics. Part C, Seminars in medical genetics, 142C 4, 276-83

Gilbert, Donald L; Buncher, C Ralph 2006. Epileptiform discharges and the behavior of children with epilepsy. The Journal of pediatrics, 149 2, 283; author reply 28

Wetherill, Yelena B; Hess-Wilson, Janet K; Comstock, Clay E S; Shah, Supriya A; Buncher, C Ralph; Sallans, Larry; Limbach, Patrick A; Schwemberger, Sandy; Babcock, George F; Knudsen, Karen E 2006. Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer. Molecular cancer therapeutics, 5 12, 3181-90

Gilbert, Donald L; Buncher, C Ralph 2005. Assessment of scientific and ethical issues in two randomized clinical trial designs for patients with Tourette's syndrome: a model for studies of multiple neuropsychiatric diagnoses. The Journal of neuropsychiatry and clinical neurosciences, 17 3, 324-32

Khoury, J C; Miodovnik, M; Buncher, C R; Kalkwarf, H; McElvy, S; Khoury, P R; Sibai, B 2004. Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 15 1, 44-50

Gilbert, Donald L; Sethuraman, Gopalan; Kotagal, Uma; Buncher, C Ralph 2003. Meta-analysis of EEG test performance shows wide variation among studies. Neurology, 60 4, 564-70

Jazieh, Abdul R; Buncher, Charles R 2002. Racial and age-related disparities in obtaining screening mammography: results of a statewide database. Southern medical journal, 95 10, 1145-8

Pomerantz, W J; Dowd, M D; Buncher, C R 2001. Relationship between socioeconomic factors and severe childhood injuries. Journal of urban health : bulletin of the New York Academy of Medicine, 78 1, 141-51

Gilbert, D L; Buncher, C R 2000. An EEG should not be obtained routinely after first unprovoked seizure in childhood. Neurology, 54 3, 635-41

Iannaccone, S T; Russman, B S; Browne, R H; Buncher, C R; White, M; Samaha, F J 2000. Prospective analysis of strength in spinal muscular atrophy. DCN/Spinal Muscular Atrophy Group. Journal of child neurology, 15 2, 97-101

Buncher, C R; Morrison, J A 1998. Those confounding variables! The Journal of pediatrics, 133 2, 174-5

Linz, D H; Pinney, S M; Keller, J D; White, M; Buncher, C R 1998. Cluster analysis applied to building-related illness. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine, 40 2, 165-71

Creticos, P S; Reed, C E; Norman, P S; Khoury, J; Adkinson, N F; Buncher, C R; Busse, W W; Bush, R K; Gadde, J; Li, J T 1996. Ragweed immunotherapy in adult asthma. The New England journal of medicine, 334 8, 501-6

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R 1996. Possible misclassification did not obscure detection of exposure-response. American journal of industrial medicine, 30 5, 643-4

Russman, B S; Buncher, C R; White, M; Samaha, F J; Iannaccone, S T 1996. Function changes in spinal muscular atrophy II and III. The DCN/SMA Group. Neurology, 47 4, 973-6

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R 1995. Exposure-response analysis of mortality among coal miners in the United States. American journal of industrial medicine, 28 2, 167-84

Leikauf, G D; Kline, S; Albert, R E; Baxter, C S; Bernstein, D I; Bernstein, J; Buncher, C R 1995. Evaluation of a possible association of urban air toxics and asthma. Environmental health perspectives, 103 Suppl 6 , 253-71

Taha, J M; Tew, J M; Buncher, C R 1995. A prospective 15-year follow up of 154 consecutive patients with trigeminal neuralgia treated by percutaneous stereotactic radiofrequency thermal rhizotomy. Journal of neurosurgery, 83 6, 989-93

Betemps, E J; Buncher, C R; Clark, C S 1994. Proportional mortality analysis of wastewater treatment system workers by birthplace with comments on amyotrophic lateral sclerosis. Journal of occupational medicine. : official publication of the Industrial Medical Association, 36 1, 31-5

Samaha, F J; Buncher, C R; Russman, B S; White, M L; Iannaccone, S T; Barker, L; Burhans, K; Smith, C; Perkins, B; Zimmerman, L 1994. Pulmonary function in spinal muscular atrophy. Journal of child neurology, 9 3, 326-9

Tian, J J; Shukla, R; Buncher, C R 1994. On prediction of future observation in growth curve model. Statistics in medicine, 13 21, 2205-17

Betemps, E J; Buncher, C R 1993. Birthplace as a risk factor in motor neurone disease and Parkinson's disease. International journal of epidemiology, 22 5, 898-904

Betemps, E J; Somoza, E; Buncher, C R 1993. Hospital characteristics, diagnoses, and staff reasons associated with use of seclusion and restraint. Hospital & community psychiatry, 44 4, 367-71

Pavelic, Z P; Portugal, L G; Gootee, M J; Stambrook, P J; Smith, C; Mugge, R E; Pavelic, L; Wilson, K; Buncher, C R; Li, Y Q 1993. Retrieval of p53 protein in paraffin-embedded head and neck tumor tissues. Archives of otolaryngology--head & neck surgery, 119 11, 1206-9

Betemps, E J; Buncher, C R; Oden, M 1992. Length of time spent in seclusion and restraint by patients at 82 VA medical centers. Hospital & community psychiatry, 43 9, 912-4

Lanphear, B P; Buncher, C R 1992. Latent period for malignant mesothelioma of occupational origin. Journal of occupational medicine. : official publication of the Industrial Medical Association, 34 7, 718-21

Russman, B S; Iannacone, S T; Buncher, C R; Samaha, F J; White, M; Perkins, B; Zimmerman, L; Smith, C; Burhans, K; Barker, L 1992. Spinal muscular atrophy: new thoughts on the pathogenesis and classification schema. Journal of child neurology, 7 4, 347-53

Buncher, C R; Collins, J J; Halperin, W 1991. Possible progress and unresolved conflicts resulting from guidelines on good epidemiologic practices. Journal of occupational medicine. : official publication of the Industrial Medical Association, 33 12, 1261-4

Buncher, C R; Succop, P A; Dietrich, K N 1991. Structural equation modeling in environmental risk assessment. Environmental health perspectives, 90 , 209-13

Collins, J J; Buncher, C R; Halperin, W 1991. Managing the quality and conduct of epidemiologic studies. Journal of occupational medicine. : official publication of the Industrial Medical Association, 33 12, 1213-5

Denman, D L; Legorreta, R A; Kier, A B; Elson, H R; White, M L; Buncher, C R; Lewis, G C; Born, A M; Sundararaman, S; Aron, B S 1991. Therapeutic responses of spontaneous canine malignancies to combinations of radiotherapy and hyperthermia. International journal of radiation oncology, biology, physics, 21 2, 415-22

Foulkes, E C; Mort, T L; Buncher, C R 1991. Intestinal cadmium permeability in mature and immature rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 197 4, 477-81

Buncher, C R; Samaha, F; Iannaccone, S T; Russman, B S; Cook, J D; White, M; McLaughlin, C 1990. Statistical considerations in the study of spinal muscular atrophy. Dallas-Cincinnati-Newington Spinal Muscular Atrophy (DCN-SMA) Study Group. Muscle & nerve, 13 Suppl , S45-8

Dietrich, K N; Succop, P A; Bornschein, R L; Krafft, K M; Berger, O; Hammond, P B; Buncher, C R 1990. Lead exposure and neurobehavioral development in later infancy. Environmental health perspectives, 89 , 13-9

Buncher, C R 1989. Did formaldehyde cause lung cancer? Journal of occupational medicine. : official publication of the Industrial Medical Association, 31 11, 885

Shukla, R; Bornschein, R L; Dietrich, K N; Buncher, C R; Berger, O G; Hammond, P B; Succop, P A 1989. Fetal and infant lead exposure: effects on growth in stature. Pediatrics, 84 4, 604-12

Buncher, C R 1988. Statistics in sports injury research. The American journal of sports medicine, 16 Suppl 1 , S57-62

Fowler, N O; Gabel, M; Buncher, C R 1988. Cardiac tamponade: a comparison of right versus left heart compression. Journal of the American College of Cardiology, 12 1, 187-93

Keller, C S; Noyes, F R; Buncher, C R 1988. The medical aspects of soccer injury epidemiology. The American journal of sports medicine, 16 Suppl 1 , S105-12

Specker, B L; Saenger, E L; Buncher, C R; McDevitt, R A 1987. Pulmonary embolism and lung scanning: cost-effectiveness and benefit:risk. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 28 10, 1521-30

Saenger, E L; Buncher, C R; Specker, B L; McDevitt, R A 1985. Determination of clinical efficacy: nuclear medicine as applied to lung scanning. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 26 7, 793-806

Berlin, N I; Buncher, C R; Fontana, R S; Frost, J K; Melamed, M R 1984. The National Cancer Institute Cooperative Early Lung Cancer Detection Program. Results of the initial screen (prevalence). Early lung cancer detection: Introduction. The American review of respiratory disease, 130 4, 545-9

Bonventre, P F; Linnemann, C; Weckbach, L S; Staneck, J L; Buncher, C R; Vigdorth, E; Ritz, H; Archer, D; Smith, B 1984. Antibody responses to toxic-shock-syndrome (TSS) toxin by patients with TSS and by healthy staphylococcal carriers. The Journal of infectious diseases, 150 5, 662-6

Gartside, P S; Buncher, C R; Lerner, S 1982. Relationship of air lead and blood lead for workers at an automobile battery factory. International archives of occupational and environmental health, 50 1, 1-10

Linnemann, C C; Staneck, J L; Hornstein, S; Barden, T P; Rauh, J L; Bonventre, P F; Buncher, C R; Beiting, A 1982. The epidemiology of genital colonization with Staphylococcus aureus. Annals of internal medicine, 96 6 Pt 2, 940-4

Emmett, E A; Buncher, C R; Suskind, R B; Rowe, K W 1981. Skin and eye diseases among arc welders those exposed to welding operations. Journal of occupational medicine. : official publication of the Industrial Medical Association, 23 2, 85-90

Buncher, C R 1980. National Cancer Institute study: evaluation of computed tomography in the diagnosis of intracranial neoplasms. II. Was randomization necessary? Radiology, 136 3, 651-5

Elia, V J; Anderson, L A; Macdonald, T J; Carson, A; Buncher, C R; Brooks, S M 1980. Determination of urinary mandelic and phenylglyoxylic acids in styrene exposed workers and a control population. American Industrial Hygiene Association journal, 41 12, 922-6

Maxon, H R; Saenger, E L; Thomas, S R; Buncher, C R; Kereiakes, J G; Shafer, M L; McLaughlin, C A 1980. Clinically important radiation-associated thyroid disease. A controlled study. JAMA, 244 16, 1802-5

Tsang, R; Abrams, L; Joyce, T H; Buncher, C R; Steichen, J J 1979. Ionized Ca in neonates in relation to gestational age. The Journal of pediatrics, 94 1, 126-9

Mandybur, T I; Ormsby, I; Buncher, C R 1978. Enhanced development of mammary tumors in rats following transplacental and neonatal exposure to ethylnitrosourea. Cancer research, 38 10, 3182-5

Buncher, C R 1977. The golden fleece award: a control? Science (New York, N.Y.), 197 4308, 1036

Buncher, C R 1977. Health records. Science (New York, N.Y.), 195 4277, 440

Glueck, C J; Mellies, M J; Srivastava, L; Knowles, H C; Fallat, R W; Tsang, R C; Wacholder, S; Buncher, C R 1977. Insulin, obesity, and triglyceride interrelationships in sixteen children with familial hypertriglyceridemia. Pediatric research, 11 1 Pt 1, 13-9

Kuzma, R J; Kuzma, C M; Buncher, C R 1977. Ohio drinking water source and cancer rates. American journal of public health, 67 8, 725-9

Maxon, H R; Thomas, S R; Saenger, E L; Buncher, C R; Kereiakes, J G 1977. Ionizing irradiation and the induction of clinically significant disease in the human thyroid gland. The American journal of medicine, 63 6, 967-78

Buncher, C R 1976. On professor Okun's paper. American journal of public health, 66 11, 1108

Linnemann, C C; Levinson, J E; Buncher, C R; Schiff, G M 1975. Rubella antibody levels in juvenile rheumatoid arthritis. Annals of the rheumatic diseases, 34 4, 354-8

Namboodiri, K K; Elston, R C; Glueck, C J; Fallat, R; Buncher, C R; Tsang, R 1975. Bivariate analyses of cholesterol and triglyceride levels in families in which probands have type IIb lipoprotein phenotype. American journal of human genetics, 27 4, 454-71

Plank, S J; Buncher, C R 1975. Maternal ABO groups and the sex ratio of live births. Human heredity, 25 3, 226-33

Glueck, C J; Fallat, R W; Tsang, R; Buncher, C R 1974. Hyperlipemia in progeny of parents with myocardial infarction before age 50. American journal of diseases of children (1960), 127 1, 70-5

Lutmer, R F; Parsons, D; Glueck, C J; Morrison, J A; Stewart, L; Brazier, J B; Buncher, C R; Ishikawa, T T 1974. Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma. Journal of lipid research, 15 6, 611-4

Buncher, C R 1973. Sounding board "administratively significant". The New England journal of medicine, 289 3, 155-6

Glueck, C J; Fallat, R; Buncher, C R; Tsang, R; Steiner, P 1973. Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds. Metabolism: clinical and experimental, 23 2, 1403-28

Glueck, C J; Tsang, R; Fallat, R; Buncher, C R; Evans, G; Steiner, P 1973. Familial hypertriglyceridemia: studies in 130 children and 45 siblings of 36 index cases. Metabolism: clinical and experimental, 22 10, 1287-309

Tal, C; Raychaudhuri, A; Megel, H; Herberman, R B; Buncher, C R 1973. Simplified technique for the T-globulin cancer test. Journal of the National Cancer Institute, 51 1, 33-43

Blackwell, B; Bloomfield, S S; Buncher, C R 1972. Demonstration to medical students of placebo responses and non-drug factors. Lancet (London, England), 1 7763, 1279-82

Sampson, R J; Key, C R; Buncher, C R; Iijima, S 1971. Smallest forms of papillary carcinoma of the thyroid. A study of 141 microcarcinomas less than 0.1 cm in greatest dimension. Archives of pathology, 91 4, 334-9

Sampson, R J; Key, C R; Buncher, C R; Oka, H; Iijima, S 1970. Papillary carcinoma of the thyroid gland. Sizes of 525 tumors found at autopsy in Hiroshima and Nagasaki. Cancer, 25 6, 1391-3

Sampson, R J; Oka, H; Key, C R; Buncher, C R; Iijima, S 1970. Metastases from occult thyroid carcinoma. An autopsy study from Hiroshima and Nagasaki, Japan. Cancer, 25 4, 803-11

Buncher, C R 1969. Cigarette smoking and duration of pregnancy. American journal of obstetrics and gynecology, 103 7, 942-6

Dear, H D; Buncher, C R; Sawayama, T 1969. Changes in electrocardiogram and serum potassium values following glucose ingestion. Archives of internal medicine, 124 1, 25-8

Kimura, K; Hiramoto, T; Buncher, C R 1969. Gastric xanthelasma. Archives of pathology, 87 1, 110-7

Sampson, R J; Key, C R; Buncher, C R; Iijima, S 1969. Thyroid carcinoma in Hiroshima and Nagasaki. I. Prevalence of thyroid carcinoma at autopsy. JAMA, 209 1, 65-70

Iannaccone, S T; Browne, R H; Samaha, F J; Buncher, C R . Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group. Pediatric neurology, 9 3, 187-93

Kaufman, R A; Carroll, C D; Buncher, C R . Atlantooccipital junction: standards for measurement in normal children. AJNR. American journal of neuroradiology, 8 6, 995-9

Keller, C S; Noyes, F R; Buncher, C R . The medical aspects of soccer injury epidemiology. The American journal of sports medicine, 15 3, 230-7

Maxon, H R; Saenger, E L; Buncher, C R; Thomas, S R; Kereiakes, J G; Shafer, M L; McLaughlin, C A . Radiation-associated carcinoma of the salivary glands. A controlled study. The Annals of otology, rhinology, and laryngology, 90 2 Pt 1, 107-8

Rice, Carol; Jin, Na; Cocco, P; Dosemeci, M; Buncher, C R . The exposure metric: does including time since exposure in the calculation of working lifetime exposure provide a better understanding of disease risk than the cumulative exposure? La Medicina del lavoro, 102 4, 343-9