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Is one of the nation's 1st environmental health science research programs and the region's only center of its kind.
Funded by the National Institute of Environmental Health Sciences, NIEHS award P30 ES006096.
CEG members are among those scientists and clinicians who were asked to provide expert help following the February 3, 2023, train derailment and environmental disaster in East Palestine, OH. This has included responding to media inquiries and stakeholder concerns. Individuals and groups who wish to learn more about strategies for addressing environmental health hazards are encouraged to click on the red button below for LESSONS LEARNED on the Road to Environmental Cleanup.
Lessons Learned
Lessons Learned was developed through collaborative efforts of the UC Center for Environmental Genetics, the University of Pennsylvania Center for Excellence in Environmental Toxicology, and the MIT Superfund Research Program Center
The Center for Environmental Genetics is one of the nation's 1st environmental health science research programs and the region's only center of its kind.
To continue to be a leading force in the study of gene-environment interactions (GXE) and research translation.
To conduct innovative, multidisciplinary GxE research and translate understanding of risk stratification to disease prevention via community empowerment. Our work serves the advancement of precision medicine and precision environmental health as we aim to make disease prevention and treatment as empirical as possible by taking account of an individual’s genomics, pre-existing conditions, exposures, and potential risk factors -- be they unique to that individual or the population segment in which he or she belongs (e.g., age group, race, ethnicity, sex, place of residence, etc.).
CEG researchers devote special attention to the early origins of disease; windows of susceptibility (e.g., in utero, puberty); the interplay between genetics and epigenetics; genomics, epigenomics and other -omics (proteomics, metabolomics, metagenomics, and metallomics); the influence of lifestyle modifiers such as diet or stress on epigenetic reprogramming; and, finally, the data void related to continuous lifelong editing of early developmental programming and the potential for transgenerational effects.
Learn more about CEG
The CEG is led by Director Susan M. Pinney, Ph.D., FACE. A Fellow of the American College of Epidemiology, Pinney has conducted research in environmental epidemiology for more than 35 years. She has served as the chief epidemiologist of the Fernald Medical Monitoring program (predecessor to the Fernald Community Cohort) since its inception, responsible for yearly data collection and periodic examinations on almost 10,000 cohort members, including the collection and storage of 160,000 biospecimens. Dr. Pinney also has been a member of the NCI-funded Genetic Epidemiology of Lung Cancer Consortium (GELCC) since its inception in 1997. Dr. Pinney collaborated with Dr. Marilyn Howarth of the University of Pennsylvania Center for Excellence in Environmental Toxicology and Dr. Kathleen Vandiver of the MIT Superfund Research Program Center to develop Lessons Learned on the Road to Environmental Cleanup, the set of a set of interactive educational modules, linked above, that revisit three major environmental clean-up sites and convey strategies that community members and other stakeholders can use to navigate what is often a tension-filled, long-term process.