Today is Tuesday, Jan. 22, 2019

Department of Environmental Health

Center for Environmental Genetics

Recent CEG Publications

  • Cover of the Journal of Applied ToxicologyHufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV. Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F<sub>1</sub> fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects. J Appl Toxicol. 2018 Dec 18. PMID: 30561030. 
  • Cover of the journal Chronic Diseases and Translational Medicine Li T, Hu R, Chen Z, Li Q, Huang S, Zhu Z, Zhou LF. Fine particulate matter (PM<sub>2.5</sub>): The culprit for chronic lung diseases in China. Chronic Dis Transl Med. 2018 Aug 28;4(3):176-186. doi: 10.1016/j.cdtm.2018.07.002. eCollection 2018 Sep. PMID: 30276364; PMCID: PMC6160608. Dr. Shouxiong Huang is another successful CEG Next Generation Biomedical Investigator (NGBI award, 2014--2015).
  • Sharma M, Zhang X, Huang S. Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking. J Vis Exp. 2018 Oct 29;(140). doi: 10.3791/57528. PMID: 30417862. Listen to Dr. Shouxiong Huang very briefly introduce the article here on the publisher's website.

  • Cover of the journal Pediatric ResearchBuck CO, Eliot MN, Kelsey KT, Calafat AM, Chen A, Ehrlich S, Lanphear BP, Braun JM. Prenatal exposure to perfluoroalkyl substances and adipocytokines: the HOME Study. Pediatr Res. 2018 Sep 13. doi: 10.1038/s41390-018-0170-1. [Epub ahead of print] PMID: 30250302. Dr Shelley Ehrlich received a $20,0000 CEG Innovator award (CEG Pilot Projects Program) in 2014 for another collaborative study of Bisphenol A (BPA) microRNA and Gestational Diabetes Mellitus (GDM).
  • Choi H, Dostal M, Pastorkova A, Rossner P Jr, Sram RJ, Ho SM.  Greater susceptibility of girls to airborne Benzo[a]pyrene for obesity-associated childhood asthma.  Environ Int. 2018 Sep 17;121(Pt 1):308-316. doi: 10.1016/j.envint.2018.08.061. [Epub ahead of print] PMID: 30237028 [PubMed - as supplied by publisher]
  • Cover of the Journal of Exposure Science and Environmental Epidemiology, June 2018Kim S, Xu X, Zhang Y, Zheng X, Liu R, Dietrich K, Reponen T, Ho SM, Xie C, Sucharew H, Huo X, Chen A. Metal concentrations in pregnant women and neonates from informal electronic waste recycling. J Expo Sci Environ Epidemiol. 2018 Aug 15. doi: 10.1038/s41370-018-0054-9. PMID: 30111780.
  • Giannini CM, Herrick RL, Buckholz JM, Daniels AR, Biro FM, Pinney SM . Comprehension and Perceptions of Study Participants Upon Receiving Perfluoroalkyl Substance Exposure Biomarker Results. Int J Hyg Environ Health. 2018 Jul 16. pii: S1438-4639(18)30148-2. PMID: 30025914.
  • Cover of the journal Carcinogenesis, June 2018Andrade EB, Magalhães A, Puga A, Costa M, Bravo J, Portugal CC, Ribeiro A, Correia-Neves M, Faustino A, Firon A, Trieu-Cuot P, Summavielle T, Ferreira P. A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection. Nat Commun. 2018 Aug 7;9(1):3138. doi: 10.1038/s41467-018-05492-y. PMID: 30087335;  PMCID: PMC6081475.
  • Blake BE, Pinney SM, Hines EP, Fenton SE, Ferguson KK. Associations between serum perfluoroalkyl substance (PFAS) levels and measures of thyroid hormone, kidney function, and body mass index in the Fernald Community Cohort. Environ Pollution. In press 2018 July.
  • Byun J, Schwartz AG, Lusk C, Wenzlaff AS… Pinney SM, Bailey-Wilson JE, Amos CI. Genome-wide Association Study of Familial Lung Cancer. Carcinogenesis. 2018 Jun 19. PMID: 29924316
  • Tommie J, Pinney SM, Nommsen-Rivers L. Serum Vitamin D status and breast cancer risk by receptor status: A systematic review. Nutrition and Cancer: An International Journal. 2018 May 21:1-17. doi: 10.1080/01635581.2018.1470653. [Epub ahead of print] PMID: 29781719
  • Cover of the journal Environmental PollutionPaulik LB, Hobbie KA, Rohlman D, Smith BW, Scott RP, Kincl L, Haynes EN, Anderson KA. Environmental and individual PAH exposures near rural natural gas extraction. Environ Pollut. 2018 May 29;241:397-405. doi: 10.1016/j. envpol.2018.05.010. [Epub ahead of print] PMID: 29857308.
  • Biro FM, Pajak A, Wolff MS, Pinney SM, Windham GC, Galvez MP, Greenspan LC, Kushi LH, Teitelbaum SL. Age of menarche in a longitudinal US cohort. In press and published online, Journal of Pediatric and Adolescent Gynecology, May 11, 2018. Doi:10.1016/j.jpag.2018.05.002. PMID: 29758276
  • Cover of the journal OBESITY June 2018Li N, Yolton K, Lanphear BP, Chen A, Kalkwarf HJ, Braun JM. Impact of Early- life Weight Status on Cognitive Abilities in Children. Obesity (Silver Spring). 2018 Jun;26(6):1088-1095. doi: 10.1002/oby.22192. PMID: 29797555. PMCID: PMC5975980.
  • Dunaway S, Odin R, Zhou L, Ji L, Zhang Y, Kadekaro AL. Natural Antioxidants: Multiple Mechanisms to Protect Skin From Solar Radiation. Front Pharmacol. 2018 Apr 24;9:392. doi: 10.3389/fphar.2018.00392. eCollection 2018. Review. PMID: 29740318. PMCID: PMC5928335. Drs. Yuhang Zhang and Analuisa Kadekaro are CEG associate members.
  • Vought V, Wang HS. Impact of common environmental chemicals bisphenol A and bisphenol S on the physiology of Lumbriculus variegatus. Environ Toxicol Pharmacol. 2018 May 8;60:225-229. [Epub ahead of print] PMID: 29763883
  • Cover of the journal EPIGENETICS, March 2018 Leung YK, Ouyang B, Niu L, Xie C, Ying J, Medvedovic M, Chen A, Weihe P, Valvi D, Grandjean P, Ho SM. Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics. 2018 Mar 21:1-32. PMID: 29560787. Lead author Dr. Yuet-Kin (Ricky) Leung directs the CEG Integrative Technologies Support (ITS Core). Co-authors Bin Ouyang MD, Liang Niu PhD, Changchun Xie PhD, Jun Ying PhD, Mario Medvedovic PhD, Aimin Chen MD, PhD, and Shuk-Mei Ho PhD are also CEG members. Dr. Shuk-Mei Ho, Director.
  • Cover of the journal EPIGENETICSVonHandorf A, Sánchez-Martín FJ, Biesiada J, Zhang H, Zhang X, Medvedovic M, Puga A. Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes. Epigenetics. 2018 Mar 21:1-32. PMID: 29561703. Lead author Andrew VonHandorf, PhDc was a 2017 CEG New Investigator Scholar, funded for the project “Effects of exposure to hexavalent chromium\ Cr(VI) exposure on CTCF regulated transcription and the Cohesin complex: Role in carcinogenesis” (Mentor: Alvaro Puga, PhD).
  • Zhang X, Chen X, Weirauch MT, Zhang X, Burleson JD, Brandt EB, Ji H. Diesel exhaust and house dust mite allergen lead to common changes in the airway methylome and hydroxymethylome. Environ Epigenet. 2018 Jul 27;4(3):dvy020. doi: 10.1093/eep/dvy020. eCollection 2018 Jul. PMID: 30090644; PMCID: PMC6063278. Xiang Zhang, PhD manages the CEG Genomics & Epigenomics Sequencing Core (GESC). Hong Ji, PhD is a CEG member and Assistant Professor of Pediatrics, Cincinnati Children's Hospital Medical Center (CCHMC). 
  • Cover of the journal NATURE, April 26, 2018Sun C, Benlekbir S, Venkatakrishnan P, Wang Y, Hong S, Hosler J, Tajkhorshid E, Rubinstein JL, Gennis RB. Structure of the alternative complex III in a supercomplex with cytochrome oxidase. Nature. 2018 Apr 25. PMID: 29695868. Jack Rubinstein, MD, is a CEG Clinical member and has collaborated with Dr. Alvaro Puga (NIEHS 5 R0 1ES024744) and Dr. Hong Sheng Wang (NIEHS R01 ES027855) on the study of fetal origins of adult cardiovascular disease. Yuhang Wang, PhD, is an Associate member of the CEG.