About the Chair
Shuk-Mei Ho, PhD is internationally recognized for her expertise in the role of hormones and endocrine disruptors on disease development including tumorigenesis in the prostate, ovary, endometrium and breast. The 2015 recipient of the University of Cincinnati’s Rieveschl Award for Distinguished Scientific Research, she has made major contributions to our understanding of the impact of heavy metals, oxidative stress and inflammation on carcinogenesis; the discovery of biomarkers for cancer detection and patient classification, and mechanism-based drug development. Dr. Ho’s research employs state-of-the-art investigative tools for genomics, transcriptomics, proteomics, epigenomics, and informatics research focused on improving predictive, preventive medicine.
Dr. Ho’s work explores the developmental origins of disease susceptibility by applying epigenetics to epidemiological studies, thereby addressing two important challenges of research in environmental exposure and human health: multiple exposures at various developmental stages and the trans-generational effects of exposure. Her recent findings on exposure to endocrine disrupting compounds (EDC), including Bisphenol A, have helped to better inform the clinical and public health communities about in utero exposure to EDC in food and drinking water. She also has obtained preliminary data implicating epigenetic dysregulation of transcriptional regulation as the bases of polycyclic aromatic hydrocarbon (PAH)-associated disorders such as asthma and cancer.
Dr. Ho is an active participant in the Endocrine Society, the Society of Toxicology, the American Association for Cancer Research, Prostate Cancer Research Program, the American Urologic Society and the Society for Basic Urologic Research (SBUR). She is past president of the latter. Today she regularly chairs scientific review and policy committees for the National Institutes of Health and the Department of Defense. She is a member of the Integration Panel of the Department of Defense Congressionally Directed Prostate Cancer Research Program, and serves on the Emerging Science Committee of the National Academy of Science. Dr. Ho has been honored by the Ohio Senate (127th General Assembly) and has received the Women in Urology Award from the SBUR and the Society of Women in Urology. In August 2014, she was profiled in the journal of Endocrine Related Cancer as a nationally and internationally recognized leader in the field.
Dr. Ho has published more than 200 papers in prestigious, peer-reviewed journals. She is Jacob G. Schmidlapp Professor and Chair of the University of Cincinnati Department of Environmental Health and Director of the Cincinnati Cancer Center. She also serves as the Director of the NIEHS funded Center for Environmental Genetics and Director of the Genomics Epigenomics and Sequencing Core.