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Department of

Cancer Biology

Recent Publications

The following are recent publications from cancer biology faculty members:

 

2018

Smith, Eric A; Krumpelbeck, Eric F; Jegga, Anil G; Prell, Malte; Matrka, Marie M; Kappes, Ferdinand; Greis, Kenneth D; Ali, Abdullah M; Meetei, Amom R; Wells, Susanne I 2018. The nuclear DEK interactome supports multi-functionality. Proteins, 86 1, 88-97

Su, Rui; Dong, Lei; Li, Chenying; Nachtergaele, Sigrid; Wunderlich, Mark; Qing, Ying; Deng, Xiaolan; Wang, Yungui; Weng, Xiaocheng; Hu, Chao; Yu, Mengxia; Skibbe, Jennifer; Dai, Qing; Zou, Dongling; Wu, Tong; Yu, Kangkang; Weng, Hengyou; Huang, Huilin; Ferchen, Kyle; Qin, Xi; Zhang, Bin; Qi, Jun; Sasaki, Atsuo T; Plas, David R; Bradner, James E; Wei, Minjie; Marcucci, Guido; Jiang, Xi; Mulloy, James C; Jin, Jie; He, Chuan; Chen, Jianjun 2018. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell, 172 1-2, 90-105.e23

Yang, Yongguang; Leonard, Marissa; Zhang, Yijuan; Zhao, Dan; Mahmoud, Charif; Khan, Shugufta; Wang, Jiang; Lower, Elyse E; Zhang, Xiaoting 2018. HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1. Cancer research, 78 2, 422-435

2017

Andrade, Kelsi; Fornetti, Jaime; Zhao, Ling; Miller, Scott C; Randall, R Lor; Anderson, Neysi; Waltz, Susan E; McHale, Mark; Welm, Alana L 2017. RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis. Science translational medicine, 9 374,

B. Bu, D. Li, J. Diao, B. Ji 2017. Mechanics of water pore formation in lipid membrane under electric field Acta Mech. Sin, 33 2, 23242

Bennett, Michael R; Pleasant, LaTawnya; Haffner, Christopher; Ma, Qing; Haffey, Wendy D; Ying, Jun; Wagner, Michael; Greis, Kenneth D; Devarajan, Prasad 2017. A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome. Biomarker insights, 12 , 1177271917695832

Berman, Adi Y; Manna, Subrata; Schwartz, Naomi S; Katz, Yardena E; Sun, Yang; Behrmann, Catherine A; Yu, Jane J; Plas, David R; Alayev, Anya; Holz, Marina K 2017. ERR? regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism. Signal transduction and targeted therapy, 2 ,

Bhattacharjee, Anukana; Wang, Yongyao; Diao, Jiajie; Price, Carolyn M 2017. Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST. Nucleic acids research, 45 21, 12311-12324

Bu, Bing; Tong, Xin; Li, Dechang; Hu, Yachong; He, Wangxiao; Zhao, Chunyu; Hu, Rui; Li, Xiaoqing; Shao, Yongping; Liu, Cong; Zhao, Qing; Ji, Baohua; Diao, Jiajie 2017. N-Terminal Acetylation Preserves ?-Synuclein from Oligomerization by Blocking Intermolecular Hydrogen Bonds. ACS chemical neuroscience, ,

Chen, Xiaoyi; Clark, Jason; Wunderlich, Mark; Fan, Cuiqing; Davis, Ashley; Chen, Song; Guan, Jun-Lin; Mulloy, James C; Kumar, Ashish; Zheng, Yi 2017. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy, 13 5, 955-966

Dwivedi, Pankaj; Greis, Kenneth D 2017. Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Experimental hematology, 46 , 9-20

Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salamonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Corrigendum: Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 4, 474

Fang, Jing; Bolanos, Lyndsey C; Choi, Kwangmin; Liu, Xiaona; Christie, Susanne; Akunuru, Shailaja; Kumar, Rupali; Wang, Dehua; Chen, Xiaoting; Greis, Kenneth D; Stoilov, Peter; Filippi, Marie-Dominique; Maciejewski, Jaroslaw P; Garcia-Manero, Guillermo; Weirauch, Matthew T; Salomonis, Nathan; Geiger, Hartmut; Zheng, Yi; Starczynowski, Daniel T 2017. Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nature immunology, 18 2, 236-245

Feng, Xuyang; Hsu, Shih-Jui; Kasbek, Christopher; Chaiken, Mary; Price, Carolyn M 2017. CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance. Nucleic acids research, 45 8, 4281-4293

He, Yun; Sun, Xiumei; Wang, Li; Mishina, Yuji; Guan, Jun-Lin; Liu, Fei 2017. Male germline recombination of a conditional allele by the widely used Dermo1-cre (Twist2-cre) transgene. Genesis (New York, N.Y. : 2000), ,

Hugo, Estefanía A; Cassels, Bruce K; Fierro, Angélica 2017. Functional roles of T3.37 and S5.46 in the activation mechanism of the dopamine D1 receptor. Journal of molecular modeling, 23 4, 142

Hunt, Brian G; Wang, Yuan-Liang; Chen, Min-Shan; Wang, Shao-Chun; Waltz, Susan E 2017. Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a PCNA-dependent manner. Environmental research, 159 , 588-594

J. Diao, L. Li, Y. Lai, Q. Zhong 2017. In vitro reconstitution of autophagosome-lysosome fusion Methods Enzymo, 586 , 365-376

Jiang, Xi; Hu, Chao; Ferchen, Kyle; Nie, Ji; Cui, Xiaolong; Chen, Chih-Hong; Cheng, Liting; Zuo, Zhixiang; Seibel, William; He, Chunjiang; Tang, Yixuan; Skibbe, Jennifer R; Wunderlich, Mark; Reinhold, William C; Dong, Lei; Shen, Chao; Arnovitz, Stephen; Ulrich, Bryan; Lu, Jiuwei; Weng, Hengyou; Su, Rui; Huang, Huilin; Wang, Yungui; Li, Chenying; Qin, Xi; Mulloy, James; Zheng, Yi; Diao, Jiajie; Jin, Jie; Li, Chong; Liu, Paul P; He, Chuan; Chen, Yuan; Chen, Jianjun 2017. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nature communications, 8 1, 2099

Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kohei; Li, Na; Kopras, Elizabeth J; Kwiatkowski, David J; Borchers, Michael T; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Mays, Maxwell; Sun, Yang; Plas, David R; Sun, Julia L; Franz, David N; Capal, Jamie K; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J 2017. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular cancer research : MCR, ,

Liu, Hongqi; Feng, Xizhi; Ennis, Kelli N; Behrmann, Catherine A; Sarma, Pranjal; Jiang, Tony T; Kofuji, Satoshi; Niu, Liang; Stratton, Yiwen; Thomas, Hala Elnakat; Yoon, Sang-Oh; Sasaki, Atsuo T; Plas, David R 2017. Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia. Cell reports, 18 9, 2088-2095

Orr-Asman, Melissa A; Chu, Zhengtao; Jiang, Min; Worley, Mariah; LaSance, Kathleen; Koch, Sheryl E; Carreira, Vinicius S; Dahche, Hanan M; Plas, David R; Komurov, Kakajan; Qi, Xiaoyang; Mercer, Carol A; Anthony, Lowell B; Rubinstein, Jack; Thomas, Hala E 2017. mTOR Kinase Inhibition Effectively Decreases Progression of a Subset of Neuroendocrine Tumors that Progress on Rapalog Therapy and Delays Cardiac Impairment. Molecular cancer therapeutics, 16 11, 2432-2441

Qing, Ying; Tian, Zhiqi; Bi, Ying; Wang, Yongyao; Long, Jiangang; Song, Chun-Xiao; Diao, Jiajie 2017. Quantitation and mapping of the epigenetic marker 5-hydroxymethylcytosine. BioEssays : news and reviews in molecular, cellular and developmental biology, 39 5,

Ruiz-Torres, Sasha J; Benight, Nancy M; Karns, Rebekah A; Lower, Elyse E; Guan, Jun-Lin; Waltz, Susan E 2017. HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical ?-catenin signaling. Oncotarget, ,

Song, Chun-Xiao; Yin, Senlin; Ma, Li; Wheeler, Amanda; Chen, Yu; Zhang, Yan; Liu, Bin; Xiong, Junjie; Zhang, Weihan; Hu, Jiankun; Zhou, Zongguang; Dong, Biao; Tian, Zhiqi; Jeffrey, Stefanie S; Chua, Mei-Sze; So, Samuel; Li, Weimin; Wei, Yuquan; Diao, Jiajie; Xie, Dan; Quake, Stephen R 2017. 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages. Cell research, ,

Tuttle, Traci R; Takiar, Vinita; Kumar, Bhavna; Kumar, Pawan; Ben-Jonathan, Nira 2017. Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells. Cancer letters, 389 , 33-40

Wacker, Rahel; Eickel, Nina; Schmuckli-Maurer, Jacqueline; Annoura, Takeshi; Niklaus, Livia; Khan, Shahid M; Guan, Jun-Lin; Heussler, Volker T 2017. LC3-association with the parasitophorous vacuole membrane of Plasmodium berghei liver stages follows a noncanonical autophagy pathway. Cellular microbiology, ,

Wang, Bo; Iyengar, Rekha; Li-Harms, Xiujie; Joo, Joung Hyuck; Wright, Christopher; Lavado, Alfonso; Horner, Linda; Yang, Mao; Guan, Jun-Lin; Frase, Sharon; Green, Douglas R; Cao, Xinwei; Kundu, Mondira 2017. The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy, , 1-16

Wang, Chenran; Yeo, Syn; Haas, Michael A; Guan, Jun-Lin 2017. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. The Journal of cell biology, 216 8, 2581-2596

Xia, Houjun; Wang, Wei; Crespo, Joel; Kryczek, Ilona; Li, Wei; Wei, Shuang; Bian, Zhaoqun; Maj, Tomasz; He, Mingxiao; Liu, Rebecca J; He, Youwen; Rattan, Ramandeep; Munkarah, Adnan; Guan, Jun-Lin; Zou, Weiping 2017. Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity. Science immunology, 2 17,

Y. Hu, Y. Lai, Y. Wang, M. Zhao, Y. Zhang, M. Crowe, Z. Tian, J. Long, J. Diao 2017. SNARE-reconstituted liposomes as controllable zeptoliter nanoreactors for macromolecules Adv. Biosys, 1 ,

Yeo, Syn Kok; Guan, Jun-Lin 2017. Breast Cancer: Multiple Subtypes within a Tumor? Trends in cancer, 3 11, 753-760

Yoon, Sang-Oh; Shin, Sejeong; Karreth, Florian A; Buel, Gwen R; Jedrychowski, Mark P; Plas, David R; Dedhar, Shoukat; Gygi, Steven P; Roux, Philippe P; Dephoure, Noah; Blenis, John 2017. Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Molecular cell, ,

Zhou, Zilan; Jafari, Mina; Sriram, Vishnu; Kim, Jinsoo; Lee, Joo-Youp; Ruiz-Torres, Sasha J; Waltz, Susan E 2017. Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy. Molecular pharmaceutics, 14 12, 4551-4559

Zhou, Zilan; Kennell, Carly; Jafari, Mina; Lee, Joo-Youp; Ruiz-Torres, Sasha J; Waltz, Susan E; Lee, Jing-Huei 2017. Sequential Delivery of Erlotinib and Doxorubicin for Enhanced Triple Negative Breast Cancer Treatment Using Polymeric Nanoparticle. International journal of pharmaceutics, ,

2016

Ben-Jonathan N, Hugo ER 2016. Bisphenols Come in Different Flavors: Is "S" Better Than "A"? Endocrinology, 157 , 1321-1323

Ben-Jonathan, Nira; Hugo, Eric R 2016. Bisphenols Come in Different Flavors: Is "S" Better Than "A"? Endocrinology, 157 4, 1321-3

Bhattacharjee, Anukana; Stewart, Jason; Chaiken, Mary; Price, Carolyn M 2016. STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function. PLoS genetics, 12 9, e1006342

Blanco, Víctor M; Chu, Zhengtao; LaSance, Kathleen; Gray, Brian D; Yan Pak, Koon; Rider, Therese; Greis, Kenneth D; Qi, Xiaoyang 2016. Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles. Oncotarget, ,

Borcherding DC, Tong W, Hugo ER, Barnard DF, Fox S, LaSance K, Shaughnessy E, Ben-Jonathan N 2016. Expression and therapeutic applications of dopamine receptor-1 (D1R) in breast cancer Oncogene, 35 , 3103-3113

Borcherding, D C; Tong, W; Hugo, E R; Barnard, D F; Fox, S; LaSance, K; Shaughnessy, E; Ben-Jonathan, N 2016. Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer. Oncogene, 35 24, 3103-13

Charles Truillet, John T. Cunningham, Matthew F. Parker, Loc T. Huynh, Crystal S. Conn, Davide Ruggero, Jason S. Lewis, Michael J. Evans 2016. Non-invasive measurement of mTORC1 signaling with 89Zr-transferrin Clinical Cancer Research, ,

Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin 2016. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes & development, 30 7, 856-69

Davis, Mindy I; Sasaki, Atsuo T; Simeonov, Anton 2016. Method for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase alpha in Quantitative High-Throughput Screening (qHTS) Bioluminescent Format. Methods in molecular biology (Clifton, N.J.), 1376 , 1-9

Fang J, Liu X, Bolanos L, Barker B, Rigolino C, Cortelezzi A, Oliva EN, Cuzzola M, Grimes HL, Fontanillo C, Komurov K, MacBeth K, Starczynowski DT 2016. A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes Nature Medicine, 22 7, 727

Ghosh, Joydeep; Kobayashi, Michihiro; Ramdas, Baskar; Chatterjee, Anindya; Ma, Peilin; Mali, Raghuveer Singh; Carlesso, Nadia; Liu, Yan; Plas, David R; Chan, Rebecca J; Kapur, Reuben 2016. S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance. The Journal of clinical investigation, 126 7, 2621-5

Gong, Jihong; Lai, Ying; Li, Xiaohong; Wang, Mengxian; Leitz, Jeremy; Hu, Yachong; Zhang, Yunxiang; Choi, Ucheor B; Cipriano, Daniel; Pfuetzner, Richard A; Südhof, Thomas C; Yang, Xiaofei; Brunger, Axel T; Diao, Jiajie 2016. C-terminal domain of mammalian complexin-1 localizes to highly curved membranes. Proceedings of the National Academy of Sciences of the United States of America, 113 47, E7590-E7599

Heaven, Michael R; Funk, Adam J; Cobbs, Archie L; Haffey, Wendy D; Norris, Jeremy L; McCullumsmith, Robert E; Greis, Kenneth D 2016. Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay. Journal of mass spectrometry : JMS, 51 1, 1-11

Hu, Rui; Diao, Jiajie; Li, Ji; Tang, Zhipeng; Li, Xiaoqing; Leitz, Jeremy; Long, Jiangang; Liu, Jiankang; Yu, Dapeng; Zhao, Qing 2016. Intrinsic and membrane-facilitated alpha-synuclein oligomerization revealed by label-free detection through solid-state nanopores Scientific reports, 6 , 20776

Huang, Huaiyi; Yang, Liang; Zhang, Pingyu; Qiu, Kangqiang; Huang, Juanjuan; Chen, Yu; Diao, JiaJie; Liu, Jiankang; Ji, Liangnian; Long, Jiangang; Chao, Hui 2016. Real-time tracking mitochondrial dynamic remodeling with two-photon phosphorescent iridium (III) complexes. Biomaterials, 83 , 321-31

Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Selective disulfide reduction for labeling and enhancement of Fab antibody fragments. Biochemical and biophysical research communications, 480 4, 752-757

Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2016. Structural characterization of expressed monoclonal antibodies by single sample mass spectral analysis after IdeS proteolysis. Biochemical and biophysical research communications, 477 3, 363-8

Klionsky DJ, Czyzyk-Krzeska MF, et al. 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy, 12 , 1-222

Lai, Ying; Choi, Ucheor B; Zhang, Yunxiang; Zhao, Minglei; Pfuetzner, Richard A; Wang, Austin L; Diao, Jiajie; Brunger, Axel T 2016. N-terminal domain of complexin independently activates calcium-triggered fusion. Proceedings of the National Academy of Sciences of the United States of America, 113 32, E4698-707

Leonard M and Zhang X 2016. First Therapeutic Aptamer: VEGF-Targeting Macugen Aptamers: Tools for Targeted Nanotherapy and Molecular Imaging, Pan Stanford Publishing , Page 319-335.

Malmersjö, Seth; Di Palma, Serena; Diao, Jiajie; Lai, Ying; Pfuetzner, Richard A; Wang, Austin L; McMahon, Moira A; Hayer, Arnold; Porteus, Matthew; Bodenmiller, Bernd; Brunger, Axel T; Meyer, Tobias 2016. Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion. The EMBO journal, ,

Pan, Ji-An; Sun, Yu; Jiang, Ya-Ping; Bott, Alex J; Jaber, Nadia; Dou, Zhixun; Yang, Bin; Chen, Juei-Suei; Catanzaro, Joseph M; Du, Chunying; Ding, Wen-Xing; Diaz-Meco, Maria T; Moscat, Jorge; Ozato, Keiko; Lin, Richard Z; Zong, Wei-Xing 2016. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular cell, 62 1, 149-151

Park, Sunmin; Buck, Michael D; Desai, Chandni; Zhang, Xin; Loginicheva, Ekaterina; Martinez, Jennifer; Freeman, Michael L; Saitoh, Tatsuya; Akira, Shizuo; Guan, Jun-Lin; He, You-Wen; Blackman, Marcia A; Handley, Scott A; Levine, Beth; Green, Douglas R; Reese, Tiffany A; Artyomov, Maxim N; Virgin, Herbert W 2016. Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation. Cell host & microbe, 19 1, 91-101

Santeford, Andrea; Wiley, Luke A; Park, Sunmin; Bamba, Sonya; Nakamura, Rei; Gdoura, Abdelaziz; Ferguson, Thomas A; Rao, P Kumar; Guan, Jun-Lin; Saitoh, Tatsuya; Akira, Shizuo; Xavier, Ramnik; Virgin, Herbert W; Apte, Rajendra S 2016. Impaired autophagy in macrophages promotes inflammatory eye disease. Autophagy, 12 10, 1876-1885

Sasaki, Atsuo T 2016. Dynamic Role of the GTP Energy Metabolism in Cancers. The Keio journal of medicine, 65 1, 21

Sedlacek, Christopher J; Nielsen, Susanne; Greis, Kenneth D; Haffey, Wendy D; Revsbech, Niels Peter; Ticak, Tomislav; Laanbroek, Hendrikus J; Bollmann, Annette 2016. Effects of Bacterial Community Members on the Proteome of the Ammonia-Oxidizing Bacterium Nitrosomonas sp. Strain Is79. Applied and environmental microbiology, 82 15, 4776-88

Song, Chun-Xiao; Diao, Jiajie; Brunger, Axel T; Quake, Stephen R 2016. Simultaneous single-molecule epigenetic imaging of DNA methylation and hydroxymethylation. Proceedings of the National Academy of Sciences of the United States of America, 113 16, 4338-43

Sumita, Kazutaka; Lo, Yu-Hua; Takeuchi, Koh; Senda, Miki; Kofuji, Satoshi; Ikeda, Yoshiki; Terakawa, Jumpei; Sasaki, Mika; Yoshino, Hirofumi; Majd, Nazanin; Zheng, Yuxiang; Kahoud, Emily Rose; Yokota, Takehiro; Emerling, Brooke M; Asara, John M; Ishida, Tetsuo; Locasale, Jason W; Daikoku, Takiko; Anastasiou, Dimitrios; Senda, Toshiya; Sasaki, Atsuo T 2016. The Lipid Kinase PI5P4Kbeta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Molecular cell, 61 2, 187-98

Sun, Chunhui; Yuan, Hebao; Wang, Li; Wei, Xiaoxi; Williams, Linford; Krebsbach, Paul H; Guan, Jun-Lin; Liu, Fei 2016. FAK Promotes Osteoblast Progenitor Cell Proliferation and Differentiation By Enhancing Wnt Signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, ,

Sun, Shaogang; Guan, Jun-Lin 2016. Modeling lymphangiosarcoma in mice. Cell cycle (Georgetown, Tex.), , 0

Takeuchi, Koh; Senda, Miki; Lo, Yu-Hua; Kofuji, Satoshi; Ikeda, Yoshiki; Sasaki, Atsuo T; Senda, Toshiya 2016. Structural reverse genetics study of the PI5P4K?-nucleotide complexes reveals the presence of the GTP bioenergetic system in mammalian cells. The FEBS journal, ,

Tuttle, Traci R; Mierzwa, Michelle L; Wells, Susanne I; Fox, Sejal R; Ben-Jonathan, Nira 2016. The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma. Cancer letters, 370 2, 279-85

Varney ME, Choi K, Bolanos L, Christie S, Fang J, Grimes HL, Maciejewski JP, Inoue JI, Starczynowski DT 2016. Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome Leukemia, 50 , 85

Wagener, Brant M; Hu, Meng; Zheng, Anni; Zhao, Xueke; Che, Pulin; Brandon, Angela; Anjum, Naseem; Snapper, Scott; Creighton, Judy; Guan, Jun-Lin; Han, Qimei; Cai, Guo-Qiang; Han, Xiaosi; Pittet, Jean-Francois; Ding, Qiang 2016. Neuronal Wiskott-Aldrich syndrome protein regulates TGF-?1-mediated lung vascular permeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30 7, 2557-69

Wang, Chenran; Chen, Song; Yeo, Syn; Karsli-Uzunbas, Gizem; White, Eileen; Mizushima, Noboru; Virgin, Herbert W; Guan, Jun-Lin 2016. Correction: Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of cell biology, 212 7, 879

Wang, Chenran; Chen, Song; Yeo, Syn; Karsli-Uzunbas, Gizem; White, Eileen; Mizushima, Noboru; Virgin, Herbert W; Guan, Jun-Lin 2016. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. The Journal of cell biology, 212 5, 545-60

Wang, Chuchu; Zhao, Chunyu; Li, Dan; Tian, Zhiqi; Lai, Ying; Diao, Jiajie; Liu, Cong 2016. Versatile Structures of α-Synuclein. Frontiers in molecular neuroscience, 9 , 48

Wang, Yongyao; Li, Linsen; Hou, Chen; Lai, Ying; Long, Jiangang; Liu, Jiankang; Zhong, Qing; Diao, Jiajie 2016. SNARE-mediated membrane fusion in autophagy. Seminars in cell & developmental biology, 60 , 97-104

X. Li, R. Hu, J. Li, X. Tong, J.J. Diao, D. Yu, Q. Zhao 2016. Non-sticky translocation of bio-molecules through Tween 20-coated solid-state nanopores in a wide pH range Appl. Phys. Lett, 109 , 143105

Yeo, Syn Kok; Guan, Jun-Lin 2016. Hierarchical heterogeneity in mammary tumors and its regulation by autophagy. Autophagy, 12 10, 1960-1961

Yeo, Syn Kok; Wen, Jian; Chen, Song; Guan, Jun-Lin 2016. Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgf?/Smad Signaling. Cancer research, 76 11, 3397-410

Z. Tian, Y. Hu, J. Long, J. Liu, J. Diao 2016. Single-molecule biophysical studies of neurotransmitter release Prog. Biochem. Biophys, 43 , 946

Zhang Y, Leonard M, Shu Y, Yang Y, Shu D, Guo P, and Zhang X. 2016. Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles ACS Nano , 11 1, 335-346

2015

Adams AK, Bolanos LC, Dexheimer PJ, Karns RA, Aronow BJ, Komurov K, Jegga AG, Casper KA, Patil YJ, Wilson KM, Starczynowski DT, Wells SI 2015. IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival Oncotarget, 6 41, 43395

Ågerstam, Helena; Karlsson, Christine; Hansen, Nils; Sandén, Carl; Askmyr, Maria; von Palffy, Sofia; Högberg, Carl; Rissler, Marianne; Wunderlich, Mark; Juliusson, Gunnar; Richter, Johan; Sjöström, Kjell; Bhatia, Ravi; Mulloy, James C; Järås, Marcus; Fioretos, Thoas 2015. Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America, 112 34, 10786-91

Benight, Nancy M; Wagh, Purnima K; Zinser, Glendon M; Peace, Belinda E; Stuart, William D; Vasiliauskas, Juozas; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2015. HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses. Oncotarget, 6 19, 17445-61

Benito, Juliana M; Godfrey, Laura; Kojima, Kensuke; Hogdal, Leah; Wunderlich, Mark; Geng, Huimin; Marzo, Isabel; Harutyunyan, Karine G; Golfman, Leonard; North, Phillip; Kerry, Jon; Ballabio, Erica; Chonghaile, Triona Ní; Gonzalo, Oscar; Qiu, Yihua; Jeremias, Irmela; Debose, LaKiesha; O'Brien, Eric; Ma, Helen; Zhou, Ping; Jacamo, Rodrigo; Park, Eugene; Coombes, Kevin R; Zhang, Nianxiang; Thomas, Deborah A; O'Brien, Susan; Kantarjian, Hagop M; Leverson, Joel D; Kornblau, Steven M; Andreeff, Michael; Müschen, Markus; Zweidler-McKay, Patrick A; Mulloy, James C; Letai, Anthony; Milne, Thomas A; Konopleva, Marina 2015. MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199. Cell reports, 13 12, 2715-27

Ben-Jonathan, Nira; Hugo, Eric 2015. Prolactin (PRL) in adipose tissue: regulation and functions. Advances in experimental medicine and biology, 846 , 1-35

Brunger, Axel T; Cipriano, Daniel J; Diao, Jiajie 2015. Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins. Critical reviews in biochemistry and molecular biology, 50 3, 231-41

Cost, Nicolas G; Czyzyk-Krzeska, Maria F 2015. Regulation of autophagy by two products of one gene: TRPM3 and miR-204. Molecular & cellular oncology, 2 4, e1002712

Demitrack, Elise S; Gifford, Gail B; Keeley, Theresa M; Carulli, Alexis J; VanDussen, Kelli L; Thomas, Dafydd; Giordano, Thomas J; Liu, Zhenyi; Kopan, Raphael; Samuelson, Linda C 2015. Notch signaling regulates gastric antral LGR5 stem cell function. The EMBO journal, 34 20, 2522-36

Diao, Jiajie; Grob, Patricia; Cipriano, Daniel J; Kyoung, Minjoung; Zhang, Yunxiang; Shah, Sachi; Nguyen, Amie; Padolina, Mark; Srivastava, Ankita; Vrljic, Marija; Shah, Ankita; Nogales, Eva; Chu, Steven; Brunger, Axel T 2015. Correction: Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. eLife, 4 , e12289

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